NL7704425A - 1,3-dihydro-heteroarylspiro (isobenzofuranen). - Google Patents
1,3-dihydro-heteroarylspiro (isobenzofuranen).Info
- Publication number
- NL7704425A NL7704425A NL7704425A NL7704425A NL7704425A NL 7704425 A NL7704425 A NL 7704425A NL 7704425 A NL7704425 A NL 7704425A NL 7704425 A NL7704425 A NL 7704425A NL 7704425 A NL7704425 A NL 7704425A
- Authority
- NL
- Netherlands
- Prior art keywords
- isobenzofurans
- dihydro
- spiro
- heteroaryl
- heteroaryl spiro
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/24—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
- C07D213/28—Radicals substituted by singly-bound oxygen or sulphur atoms
- C07D213/30—Oxygen atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/26—Psychostimulants, e.g. nicotine, cocaine
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
- C07D333/02—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings
- C07D333/04—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom
- C07D333/06—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to the ring carbon atoms
- C07D333/22—Radicals substituted by doubly bound hetero atoms, or by two hetero atoms other than halogen singly bound to the same carbon atom
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Engineering & Computer Science (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Psychiatry (AREA)
- Veterinary Medicine (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Pain & Pain Management (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Furan Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US05/681,509 US4031224A (en) | 1976-04-29 | 1976-04-29 | 1,3-Dihydro-heteroarylspiro (isobenzofuran)s |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| NL7704425A true NL7704425A (nl) | 1977-11-01 |
Family
ID=24735573
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| NL7704425A NL7704425A (nl) | 1976-04-29 | 1977-04-22 | 1,3-dihydro-heteroarylspiro (isobenzofuranen). |
Country Status (22)
| Country | Link |
|---|---|
| US (1) | US4031224A (xx) |
| JP (1) | JPS52133974A (xx) |
| AT (1) | AT368502B (xx) |
| AU (1) | AU517471B2 (xx) |
| BE (1) | BE854133A (xx) |
| CA (1) | CA1084493A (xx) |
| DE (1) | DE2718455A1 (xx) |
| DK (1) | DK185977A (xx) |
| ES (1) | ES458127A1 (xx) |
| FI (1) | FI771337A (xx) |
| FR (1) | FR2349587A1 (xx) |
| GB (1) | GB1571077A (xx) |
| GR (1) | GR71645B (xx) |
| IE (1) | IE45037B1 (xx) |
| IL (1) | IL51957A0 (xx) |
| IT (1) | IT1113573B (xx) |
| LU (1) | LU77215A1 (xx) |
| NL (1) | NL7704425A (xx) |
| NO (1) | NO771442L (xx) |
| PT (1) | PT66492B (xx) |
| SE (1) | SE7704857L (xx) |
| ZA (1) | ZA772548B (xx) |
Families Citing this family (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4409229A (en) * | 1977-12-02 | 1983-10-11 | Hoechst-Roussel Pharmaceuticals, Inc. | Antidepressive and tranquilizing substituted 1,3-dihydrospiro[benzo(c)thiophene]s |
| IT1128095B (it) * | 1979-02-22 | 1986-05-28 | Wellcome Found | Derivati imidazolici e loro sali dotati di attivita farmacologica e procedimento per la loro preparazione |
| US4263317A (en) * | 1979-09-06 | 1981-04-21 | Hoechst-Roussel Pharmaceuticals, Inc. | Spiro[cyclohexane-1,1'(3'H)-isobenzofuran]s |
| US5206240A (en) * | 1989-12-08 | 1993-04-27 | Merck & Co., Inc. | Nitrogen-containing spirocycles |
| EP0450761A1 (en) * | 1990-03-02 | 1991-10-09 | Merck & Co. Inc. | Spirocyclic oxytocin antagonists |
| US5648352A (en) * | 1991-09-13 | 1997-07-15 | Merck & Co., Inc. | Piperazinylcamphorsulfonyl oxytocin antagonists |
| US5693643A (en) * | 1991-09-16 | 1997-12-02 | Merck & Co., Inc. | Hydantoin and succinimide-substituted derivatives of spiroindanylcamphorsulfonyl oxytocin antagonists |
| US6376505B1 (en) | 1997-05-29 | 2002-04-23 | Eli Lilly And Company | 5-HT1A and 5-HT1Dαdalpha antagonists |
| JP2002500668A (ja) * | 1997-05-29 | 2002-01-08 | イーライ・リリー・アンド・カンパニー | ５−ＨＴ▲下１Ａ▼および５−ＨＴ▲下１Ｄα▼アンタゴニスト |
| WO2011137024A1 (en) * | 2010-04-26 | 2011-11-03 | Merck Sharp & Dohme Corp. | Novel spiropiperidine prolylcarboxypeptidase inhibitors |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3959475A (en) * | 1973-12-12 | 1976-05-25 | American Hoechst Corporation | Substituted 1,3-dihydrospiro(isobenzofuran)s |
| US3980787A (en) * | 1975-08-25 | 1976-09-14 | American Hoechst Corporation | 3-Phenylspiro[isobenzofuran-1,4'-piperidine]sulfenamides and derivatives |
-
1976
- 1976-04-29 US US05/681,509 patent/US4031224A/en not_active Expired - Lifetime
-
1977
- 1977-04-22 NL NL7704425A patent/NL7704425A/xx not_active Application Discontinuation
- 1977-04-23 ES ES458127A patent/ES458127A1/es not_active Expired
- 1977-04-26 DE DE19772718455 patent/DE2718455A1/de not_active Withdrawn
- 1977-04-26 NO NO771442A patent/NO771442L/no unknown
- 1977-04-27 FI FI771337A patent/FI771337A/fi not_active Application Discontinuation
- 1977-04-27 IL IL51957A patent/IL51957A0/xx unknown
- 1977-04-27 SE SE7704857A patent/SE7704857L/xx unknown
- 1977-04-27 LU LU77215A patent/LU77215A1/xx unknown
- 1977-04-27 IT IT22899/77A patent/IT1113573B/it active
- 1977-04-27 GR GR53305A patent/GR71645B/el unknown
- 1977-04-28 JP JP4976977A patent/JPS52133974A/ja active Pending
- 1977-04-28 DK DK185977A patent/DK185977A/da unknown
- 1977-04-28 GB GB17786/77A patent/GB1571077A/en not_active Expired
- 1977-04-28 IE IE856/77A patent/IE45037B1/en unknown
- 1977-04-28 AU AU24647/77A patent/AU517471B2/en not_active Expired
- 1977-04-28 ZA ZA00772548A patent/ZA772548B/xx unknown
- 1977-04-28 PT PT66492A patent/PT66492B/pt unknown
- 1977-04-28 AT AT0302677A patent/AT368502B/de not_active IP Right Cessation
- 1977-04-28 CA CA277,261A patent/CA1084493A/en not_active Expired
- 1977-04-29 BE BE177158A patent/BE854133A/xx unknown
- 1977-04-29 FR FR7713019A patent/FR2349587A1/fr active Granted
Also Published As
| Publication number | Publication date |
|---|---|
| FR2349587A1 (fr) | 1977-11-25 |
| ZA772548B (en) | 1978-04-26 |
| LU77215A1 (xx) | 1977-12-01 |
| ES458127A1 (es) | 1978-11-01 |
| JPS52133974A (en) | 1977-11-09 |
| IE45037B1 (en) | 1982-06-02 |
| FR2349587B1 (xx) | 1980-03-07 |
| DK185977A (da) | 1977-10-30 |
| BE854133A (fr) | 1977-10-31 |
| AU2464777A (en) | 1978-11-02 |
| SE7704857L (sv) | 1977-10-30 |
| CA1084493A (en) | 1980-08-26 |
| FI771337A (xx) | 1977-10-30 |
| IE45037L (en) | 1977-10-29 |
| ATA302677A (de) | 1982-02-15 |
| IT1113573B (it) | 1986-01-20 |
| NO771442L (no) | 1977-11-01 |
| PT66492B (de) | 1978-12-14 |
| IL51957A0 (en) | 1977-06-30 |
| PT66492A (de) | 1977-05-01 |
| GR71645B (xx) | 1983-06-29 |
| DE2718455A1 (de) | 1977-11-10 |
| AT368502B (de) | 1982-10-25 |
| AU517471B2 (en) | 1981-08-06 |
| US4031224A (en) | 1977-06-21 |
| GB1571077A (en) | 1980-07-09 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| BV | The patent application has lapsed |