IL51957A0 - 1,3-dihydro-heteroarylspiro(isobenzofuran)s - Google Patents

1,3-dihydro-heteroarylspiro(isobenzofuran)s

Info

Publication number
IL51957A0
IL51957A0 IL51957A IL5195777A IL51957A0 IL 51957 A0 IL51957 A0 IL 51957A0 IL 51957 A IL51957 A IL 51957A IL 5195777 A IL5195777 A IL 5195777A IL 51957 A0 IL51957 A0 IL 51957A0
Authority
IL
Israel
Prior art keywords
heteroarylspiro
isobenzofuran
dihydro
Prior art date
Application number
IL51957A
Other languages
English (en)
Original Assignee
Hoechst Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoechst Ag filed Critical Hoechst Ag
Publication of IL51957A0 publication Critical patent/IL51957A0/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/24—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D213/28—Radicals substituted by singly-bound oxygen or sulphur atoms
    • C07D213/30—Oxygen atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/26—Psychostimulants, e.g. nicotine, cocaine
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
    • C07D333/02—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings
    • C07D333/04—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom
    • C07D333/06—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to the ring carbon atoms
    • C07D333/22—Radicals substituted by doubly bound hetero atoms, or by two hetero atoms other than halogen singly bound to the same carbon atom

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Psychiatry (AREA)
  • Veterinary Medicine (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Pain & Pain Management (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Furan Compounds (AREA)
IL51957A 1976-04-29 1977-04-27 1,3-dihydro-heteroarylspiro(isobenzofuran)s IL51957A0 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US05/681,509 US4031224A (en) 1976-04-29 1976-04-29 1,3-Dihydro-heteroarylspiro (isobenzofuran)s

Publications (1)

Publication Number Publication Date
IL51957A0 true IL51957A0 (en) 1977-06-30

Family

ID=24735573

Family Applications (1)

Application Number Title Priority Date Filing Date
IL51957A IL51957A0 (en) 1976-04-29 1977-04-27 1,3-dihydro-heteroarylspiro(isobenzofuran)s

Country Status (22)

Country Link
US (1) US4031224A (xx)
JP (1) JPS52133974A (xx)
AT (1) AT368502B (xx)
AU (1) AU517471B2 (xx)
BE (1) BE854133A (xx)
CA (1) CA1084493A (xx)
DE (1) DE2718455A1 (xx)
DK (1) DK185977A (xx)
ES (1) ES458127A1 (xx)
FI (1) FI771337A (xx)
FR (1) FR2349587A1 (xx)
GB (1) GB1571077A (xx)
GR (1) GR71645B (xx)
IE (1) IE45037B1 (xx)
IL (1) IL51957A0 (xx)
IT (1) IT1113573B (xx)
LU (1) LU77215A1 (xx)
NL (1) NL7704425A (xx)
NO (1) NO771442L (xx)
PT (1) PT66492B (xx)
SE (1) SE7704857L (xx)
ZA (1) ZA772548B (xx)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4409229A (en) * 1977-12-02 1983-10-11 Hoechst-Roussel Pharmaceuticals, Inc. Antidepressive and tranquilizing substituted 1,3-dihydrospiro[benzo(c)thiophene]s
IT1128095B (it) * 1979-02-22 1986-05-28 Wellcome Found Derivati imidazolici e loro sali dotati di attivita farmacologica e procedimento per la loro preparazione
US4263317A (en) * 1979-09-06 1981-04-21 Hoechst-Roussel Pharmaceuticals, Inc. Spiro[cyclohexane-1,1'(3'H)-isobenzofuran]s
US5206240A (en) * 1989-12-08 1993-04-27 Merck & Co., Inc. Nitrogen-containing spirocycles
EP0450761A1 (en) * 1990-03-02 1991-10-09 Merck & Co. Inc. Spirocyclic oxytocin antagonists
US5648352A (en) * 1991-09-13 1997-07-15 Merck & Co., Inc. Piperazinylcamphorsulfonyl oxytocin antagonists
US5693643A (en) * 1991-09-16 1997-12-02 Merck & Co., Inc. Hydantoin and succinimide-substituted derivatives of spiroindanylcamphorsulfonyl oxytocin antagonists
US6376505B1 (en) 1997-05-29 2002-04-23 Eli Lilly And Company 5-HT1A and 5-HT1Dαdalpha antagonists
JP2002500668A (ja) * 1997-05-29 2002-01-08 イーライ・リリー・アンド・カンパニー ５−ＨＴ▲下１Ａ▼および５−ＨＴ▲下１Ｄα▼アンタゴニスト
WO2011137024A1 (en) * 2010-04-26 2011-11-03 Merck Sharp & Dohme Corp. Novel spiropiperidine prolylcarboxypeptidase inhibitors

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3959475A (en) * 1973-12-12 1976-05-25 American Hoechst Corporation Substituted 1,3-dihydrospiro(isobenzofuran)s
US3980787A (en) * 1975-08-25 1976-09-14 American Hoechst Corporation 3-Phenylspiro[isobenzofuran-1,4'-piperidine]sulfenamides and derivatives

Also Published As

Publication number Publication date
FR2349587A1 (fr) 1977-11-25
ZA772548B (en) 1978-04-26
LU77215A1 (xx) 1977-12-01
ES458127A1 (es) 1978-11-01
JPS52133974A (en) 1977-11-09
IE45037B1 (en) 1982-06-02
FR2349587B1 (xx) 1980-03-07
DK185977A (da) 1977-10-30
BE854133A (fr) 1977-10-31
AU2464777A (en) 1978-11-02
SE7704857L (sv) 1977-10-30
CA1084493A (en) 1980-08-26
FI771337A (xx) 1977-10-30
IE45037L (en) 1977-10-29
ATA302677A (de) 1982-02-15
IT1113573B (it) 1986-01-20
NL7704425A (nl) 1977-11-01
NO771442L (no) 1977-11-01
PT66492B (de) 1978-12-14
PT66492A (de) 1977-05-01
GR71645B (xx) 1983-06-29
DE2718455A1 (de) 1977-11-10
AT368502B (de) 1982-10-25
AU517471B2 (en) 1981-08-06
US4031224A (en) 1977-06-21
GB1571077A (en) 1980-07-09

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