DK1809743T3 - Strukturel nukleinsyre-styret kemisk syntese - Google Patents

Strukturel nukleinsyre-styret kemisk syntese

Info

Publication number
DK1809743T3
DK1809743T3 DK05800754T DK05800754T DK1809743T3 DK 1809743 T3 DK1809743 T3 DK 1809743T3 DK 05800754 T DK05800754 T DK 05800754T DK 05800754 T DK05800754 T DK 05800754T DK 1809743 T3 DK1809743 T3 DK 1809743T3
Authority
DK
Denmark
Prior art keywords
nucleic acid
composition
chemical synthesis
reaction
structural nucleic
Prior art date
Application number
DK05800754T
Other languages
English (en)
Inventor
Nils Jakob Vest Hansen
Peter Blakskjaer
Margit Haahr Hansen
Lars Kolster Petersen
Tara Renee Heitner
Original Assignee
Vipergen Aps
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Vipergen Aps filed Critical Vipergen Aps
Application granted granted Critical
Publication of DK1809743T3 publication Critical patent/DK1809743T3/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/10—Processes for the isolation, preparation or purification of DNA or RNA
    • C12N15/1034—Isolating an individual clone by screening libraries
    • C12N15/1075—Isolating an individual clone by screening libraries by coupling phenotype to genotype, not provided for in other groups of this subclass
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
    • C07B61/00—Other general methods
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/10—Processes for the isolation, preparation or purification of DNA or RNA
    • C12N15/1034—Isolating an individual clone by screening libraries
    • C12N15/1068—Template (nucleic acid) mediated chemical library synthesis, e.g. chemical and enzymatical DNA-templated organic molecule synthesis, libraries prepared by non ribosomal polypeptide synthesis [NRPS], DNA/RNA-polymerase mediated polypeptide synthesis
DK05800754T 2004-11-08 2005-11-08 Strukturel nukleinsyre-styret kemisk syntese DK1809743T3 (da)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
EP04105597 2004-11-08
US68784905P 2005-06-07 2005-06-07
US72534705P 2005-10-11 2005-10-11
PCT/DK2005/000714 WO2006048025A1 (en) 2004-11-08 2005-11-08 Structural nucleic acid guided chemical synthesis

Publications (1)

Publication Number Publication Date
DK1809743T3 true DK1809743T3 (da) 2009-05-04

Family

ID=34929821

Family Applications (1)

Application Number Title Priority Date Filing Date
DK05800754T DK1809743T3 (da) 2004-11-08 2005-11-08 Strukturel nukleinsyre-styret kemisk syntese

Country Status (16)

Country Link
US (2) US8202823B2 (da)
EP (1) EP1809743B1 (da)
JP (1) JP4931825B2 (da)
KR (1) KR101411361B1 (da)
CN (3) CN101914528B (da)
AT (1) ATE419344T1 (da)
AU (1) AU2005300886B2 (da)
CA (1) CA2587010C (da)
DE (1) DE602005012139D1 (da)
DK (1) DK1809743T3 (da)
EA (1) EA024849B1 (da)
ES (1) ES2320361T3 (da)
IL (1) IL183013A (da)
NZ (1) NZ555698A (da)
WO (1) WO2006048025A1 (da)
ZA (1) ZA200704520B (da)

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WO2002102820A1 (en) 2001-06-20 2002-12-27 Nuevolution A/S Nucleoside derivatives for library preparation
IL163822A0 (en) 2002-03-15 2005-12-18 Nuevolution As An improved method for synthesising templated molecules
WO2004013070A2 (en) 2002-08-01 2004-02-12 Nuevolution A/S Multi-step synthesis of templated molecules
PT1558744E (pt) 2002-10-30 2011-09-22 Nuevolution As Codificação enzimática
ATE450609T1 (de) 2002-12-19 2009-12-15 Nuevolution As Durch quasizufallsstrukturen und funktionen geführte synthesemethode
EP1597395A2 (en) 2003-02-21 2005-11-23 Nuevolution A/S Method for producing second-generation library
ATE424455T1 (de) 2003-03-20 2009-03-15 Nuevolution As Ligationsvermittelnde codierung von kleinen molekülen
EP1670939B1 (en) 2003-09-18 2009-11-04 Nuevolution A/S A method for obtaining structural information concerning an encoded molecule and method for selecting compounds
ATE447020T1 (de) 2004-03-22 2009-11-15 Nuevolution As Ligationscodierung unter verwendung von oligonukleotidbausteinen
US7727721B2 (en) 2005-03-08 2010-06-01 California Institute Of Technology Hybridization chain reaction amplification for in situ imaging
EP1931806B1 (en) 2005-10-07 2011-10-05 California Institute Of Technology Pkr activation via hybridization chain reaction
DE602006018648D1 (de) 2005-12-01 2011-01-13 Nuevolution As Enzymvermittelnde kodierungsmethoden für eine effiziente synthese von grossen bibliotheken
US7928211B2 (en) 2006-05-03 2011-04-19 Vipergen Pharmaceuticals Aps Method for preparing compounds by nucleic acid directed synthesis
US8318921B2 (en) 2007-03-01 2012-11-27 California Institute Of Technology Triggered RNAi
WO2008144562A1 (en) 2007-05-16 2008-11-27 California Institute Of Technology A versatile nucleic acid hairpin motif for programming biomolecular self-assembly pathways
EP2241640B1 (en) * 2008-01-22 2016-06-22 Hiroshima University Nucleic acid-binding protein assay method and kit
US8497364B2 (en) 2008-02-27 2013-07-30 California Institute Of Technology Triggered RNAi
US8241854B2 (en) 2008-05-22 2012-08-14 California Institute Of Technology Triggered RNAi
SG2014011381A (en) 2009-02-13 2014-06-27 Chem Inc X Methods of creating and screening dna-encoded libraries
CN102473248A (zh) * 2009-07-07 2012-05-23 宝洁公司 特性-空间相似度建模
ES2713873T3 (es) 2010-04-16 2019-05-24 Nuevolution As Complejos bifuncionales y métodos para hacer y utilizar tales complejos
US8658780B2 (en) 2010-05-18 2014-02-25 California Institute Of Technology Triggered covalent probes for imaging and silencing genetic expression
US9834439B2 (en) 2010-07-20 2017-12-05 California Institute Of Technology Biomolecular self-assembly
US8877438B2 (en) 2010-07-20 2014-11-04 California Institute Of Technology Self-assembled polynucleotide structure
US8962241B2 (en) 2010-07-20 2015-02-24 California Institute Of Technology Triggered molecular geometry based bioimaging probes
EP2622073B1 (en) * 2010-09-27 2018-04-18 Vipergen A method for making an enriched library
EP3828271A1 (en) 2011-09-07 2021-06-02 X-Chem, Inc. Methods for tagging dna-encoded libraries
US9078078B1 (en) * 2011-09-15 2015-07-07 Google Inc. Call forwarding methods and systems
EA034141B1 (ru) 2012-07-13 2020-01-09 Икс-Чем, Инк. Днк-кодированные библиотеки, содержащие связи кодирующих олигонуклеотидов, не доступные для считывания полимеразами
US9856472B2 (en) 2013-07-01 2018-01-02 California Institute Of Technology Small conditional RNAs
GB201322692D0 (en) 2013-12-20 2014-02-05 Philochem Ag Production of encoded chemical libraries
US20180340174A1 (en) 2014-11-11 2018-11-29 Nanocore Aps Method for identification of molecules with desired characteristics
NL2013857B1 (en) * 2014-11-21 2016-10-11 Piculet Biosciences Tech B V Self-assembled bivalent ligand complex (SABLC) libraries and methods for screening such libraries.
JP7283727B2 (ja) 2016-06-16 2023-05-30 ヘイスタック サイエンシィズ コーポレーション コードプローブ分子のコンビナトリアル合成が指令されかつ記録されたオリゴヌクレオチド
WO2018009463A2 (en) 2016-07-05 2018-01-11 California Institute Of Technology Fractional initiator hybridization chain reaction
US10815519B2 (en) 2016-08-30 2020-10-27 California Institute Of Technology Immunohistochemistry via hybridization chain reaction
EP3619340A4 (en) 2017-05-02 2021-01-20 Haystack Sciences Corporation MOLECULES FOR THE VERIFICATION OF OLIGONUCLEOTIDE DIRECTED COMBINATIONAL SYNTHESIS AND METHOD OF MANUFACTURING AND USING THEREOF
WO2019109046A1 (en) 2017-11-30 2019-06-06 Arrakis Therapeutics, Inc. Nucleic acid-binding photoprobes and uses thereof
GB201817321D0 (en) 2018-10-24 2018-12-05 Nanna Therapeutics Ltd Microbeads for tagless encoded chemical library screening
GB201821109D0 (en) * 2018-12-21 2019-02-06 Philochem Ag Nucleic acid encoded chemical libraries
WO2020152028A1 (en) * 2019-01-22 2020-07-30 Vipergen Aps A method for screening of an in vitro display library within a cell
US11873485B2 (en) 2021-01-26 2024-01-16 California Institute Of Technology Allosteric conditional guide RNAs for cell-selective regulation of CRISPR/Cas

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WO1985000813A1 (en) * 1983-08-03 1985-02-28 The Research Foundation Of State University Of New Nucleic acid branched junctions with precisely defined migrational mobility
US5386020A (en) * 1991-01-10 1995-01-31 New York University Multiply connected, three-dimensional nucleic acid structures
US5278051A (en) * 1991-12-12 1994-01-11 New York University Construction of geometrical objects from polynucleotides
US6072044A (en) * 1996-04-26 2000-06-06 New York University Nanoconstructions of geometrical objects and lattices from antiparallel nucleic acid double crossover molecules
AU1318400A (en) 1998-10-19 2000-05-08 Board Of Trustees Of The Leland Stanford Junior University Dna-templated combinatorial library chemistry
EP1208219A1 (en) * 1999-04-08 2002-05-29 Pavel Sergeev Synthesis of biologically active compounds in cells
CN1434726A (zh) * 2000-06-08 2003-08-06 拉卓拉药物公司 包含高分子量聚环氧乙烷的多价平台分子
US7070928B2 (en) 2001-03-19 2006-07-04 President And Fellows Of Harvard College Evolving new molecular function
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WO2004024929A2 (en) * 2002-09-12 2004-03-25 Nuevolution A/S Proximity-aided synthesis of templated molecules
PT1558744E (pt) * 2002-10-30 2011-09-22 Nuevolution As Codificação enzimática
AU2003269401A1 (en) 2002-11-01 2004-05-25 Pharmacia & Upjohn Company Llc Compounds having both alpha7 nachr agonist and 5ht antagonist activity for treatment of cns diseases
AU2002953366A0 (en) 2002-12-17 2003-01-09 Hearts And Minds Crm Pty Ltd A method of analysing a business network
ATE450609T1 (de) * 2002-12-19 2009-12-15 Nuevolution As Durch quasizufallsstrukturen und funktionen geführte synthesemethode

Also Published As

Publication number Publication date
CN101914527B (zh) 2012-06-27
CN101914527A (zh) 2010-12-15
EP1809743B1 (en) 2008-12-31
EP1809743A1 (en) 2007-07-25
DE602005012139D1 (de) 2009-02-12
NZ555698A (en) 2010-07-30
CA2587010C (en) 2017-08-15
US9006150B2 (en) 2015-04-14
CN101056980B (zh) 2012-05-23
ES2320361T3 (es) 2009-05-21
EA024849B1 (ru) 2016-10-31
AU2005300886A1 (en) 2006-05-11
KR20070085977A (ko) 2007-08-27
CN101914528A (zh) 2010-12-15
AU2005300886B2 (en) 2009-11-12
US8202823B2 (en) 2012-06-19
IL183013A0 (en) 2007-08-19
ZA200704520B (en) 2008-09-25
WO2006048025A1 (en) 2006-05-11
CN101914528B (zh) 2013-04-03
CN101056980A (zh) 2007-10-17
IL183013A (en) 2011-12-29
US20130005581A1 (en) 2013-01-03
JP4931825B2 (ja) 2012-05-16
KR101411361B1 (ko) 2014-06-25
US20110045990A1 (en) 2011-02-24
CA2587010A1 (en) 2006-05-11
JP2008518607A (ja) 2008-06-05
ATE419344T1 (de) 2009-01-15
EA200701022A1 (ru) 2007-10-26

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