DK175257B1 - Formuleringer med forsinket afgivelse, fremgangsmåder til fremstilling af sådanne formuleringer og brug af en forbindelse, der er virksom til behandling af en sygdom i colon - Google Patents

Formuleringer med forsinket afgivelse, fremgangsmåder til fremstilling af sådanne formuleringer og brug af en forbindelse, der er virksom til behandling af en sygdom i colon Download PDF

Info

Publication number
DK175257B1
DK175257B1 DK199000202A DK20290A DK175257B1 DK 175257 B1 DK175257 B1 DK 175257B1 DK 199000202 A DK199000202 A DK 199000202A DK 20290 A DK20290 A DK 20290A DK 175257 B1 DK175257 B1 DK 175257B1
Authority
DK
Denmark
Prior art keywords
amylose
vitreous
active compound
release
composition
Prior art date
Application number
DK199000202A
Other languages
Danish (da)
English (en)
Other versions
DK20290A (da
DK20290D0 (da
Inventor
Stephen Gordon Ring
David Brian Archer
Michael Charles Allwood
Original Assignee
Btg Int Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Btg Int Ltd filed Critical Btg Int Ltd
Publication of DK20290A publication Critical patent/DK20290A/da
Publication of DK20290D0 publication Critical patent/DK20290D0/da
Application granted granted Critical
Publication of DK175257B1 publication Critical patent/DK175257B1/da

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/28—Dragees; Coated pills or tablets, e.g. with film or compression coating
    • A61K9/2806—Coating materials
    • A61K9/2833—Organic macromolecular compounds
    • A61K9/286—Polysaccharides, e.g. gums; Cyclodextrin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2022—Organic macromolecular compounds
    • A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
    • A61K9/2059—Starch, including chemically or physically modified derivatives; Amylose; Amylopectin; Dextrin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Epidemiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Steroid Compounds (AREA)
  • Detergent Compositions (AREA)
DK199000202A 1988-05-26 1990-01-25 Formuleringer med forsinket afgivelse, fremgangsmåder til fremstilling af sådanne formuleringer og brug af en forbindelse, der er virksom til behandling af en sygdom i colon DK175257B1 (da)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
GB8812490 1988-05-26
GB888812490A GB8812490D0 (en) 1988-05-26 1988-05-26 Delayed release formulations
GB8900581 1989-01-11
PCT/GB1989/000581 WO1989011269A1 (en) 1988-05-26 1989-05-25 Delayed release formulations

Publications (3)

Publication Number Publication Date
DK20290A DK20290A (da) 1990-01-25
DK20290D0 DK20290D0 (da) 1990-01-25
DK175257B1 true DK175257B1 (da) 2004-07-26

Family

ID=10637578

Family Applications (1)

Application Number Title Priority Date Filing Date
DK199000202A DK175257B1 (da) 1988-05-26 1990-01-25 Formuleringer med forsinket afgivelse, fremgangsmåder til fremstilling af sådanne formuleringer og brug af en forbindelse, der er virksom til behandling af en sygdom i colon

Country Status (13)

Country Link
US (1) US5108758A (ja)
EP (1) EP0343993B1 (ja)
JP (1) JP2898036B2 (ja)
AT (1) ATE75936T1 (ja)
CA (1) CA1339081C (ja)
DE (1) DE68901494D1 (ja)
DK (1) DK175257B1 (ja)
ES (1) ES2037422T3 (ja)
FI (1) FI99085C (ja)
GB (2) GB8812490D0 (ja)
GR (1) GR3004604T3 (ja)
NO (1) NO179274C (ja)
WO (1) WO1989011269A1 (ja)

Families Citing this family (71)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5484605A (en) * 1988-11-25 1996-01-16 Henning Berlin Gmbh Chemie-Und Pharmawerk Agent for treating chronically inflammatory intestinal diseases
US5468286A (en) * 1989-10-25 1995-11-21 National Starch And Chemical Investment Holding Corporation Enzymatically debranched starches as tablet excipients
GB8926639D0 (en) * 1989-11-24 1990-01-17 Agricultural & Food Res Delayed release formulations
IL98087A (en) * 1990-05-04 1996-11-14 Perio Prod Ltd Preparation for dispensing drugs in the colon
CA2041774C (en) * 1990-11-27 1994-04-19 Mircea A. Mateescu Use of cross-linked amylose as a matrix for the slow release of biologically active compounds
US5603956A (en) * 1990-11-27 1997-02-18 Labopharm Inc. Cross-linked enzymatically controlled drug release
CA2032385A1 (en) * 1990-12-17 1992-06-18 Chung Wai-Chiu Enzymatically debranched starches as tablet excipients
DE4120918A1 (de) * 1991-06-25 1993-01-07 Basf Ag Pulverfoermige praeparate aus einer wasserunloeslichen kernsubstanz und einer schutzhuelle
NL9201195A (nl) * 1992-07-03 1994-02-01 Tno Preparaat voor de gereguleerde afgifte van een werkzame stof en werkwijze ter bereiding van een dergelijk preparaat.
US5616343A (en) * 1993-03-25 1997-04-01 Labopharm, Inc. Cross-linked amylose as a binder/disintegrant in tablets
IT1265092B1 (it) * 1993-05-31 1996-10-30 Giuliani Spa Preparato per uso come integratore alimentare, o dietetico,a rilascio mirato nel colon
US5514663A (en) * 1993-10-19 1996-05-07 The Procter & Gamble Company Senna dosage form
US6028190A (en) 1994-02-01 2000-02-22 The Regents Of The University Of California Probes labeled with energy transfer coupled dyes
GB9412394D0 (en) 1994-06-21 1994-08-10 Danbiosyst Uk Colonic drug delivery composition
US6166024A (en) * 1995-03-30 2000-12-26 Mayo Foundation For Medical Education And Research Use of topical azathioprine and thioguanine to treat colorectal adenomas
US5691343A (en) * 1995-03-30 1997-11-25 Mayo Foundation For Medical Education And Research Use of topical azathioprine to treat inflammatory bowel disorders
US5811388A (en) * 1995-06-07 1998-09-22 Cibus Pharmaceutical, Inc. Delivery of drugs to the lower GI tract
US5656294A (en) * 1995-06-07 1997-08-12 Cibus Pharmaceutical, Inc. Colonic delivery of drugs
GB9516268D0 (en) 1995-08-08 1995-10-11 Danbiosyst Uk Compositiion for enhanced uptake of polar drugs from the colon
EP0858326B1 (en) * 1996-05-08 2003-04-02 Craig A. Aronchick Non-aqueous colonic purgative formulations
US5879707A (en) * 1996-10-30 1999-03-09 Universite De Montreal Substituted amylose as a matrix for sustained drug release
US6162464A (en) * 1997-03-31 2000-12-19 Inkine Pharmaceutical, Inc. Non-aqueous colonic purgative formulations
US6423299B1 (en) 1997-10-31 2002-07-23 Vincent Fischetti Composition for treatment of a bacterial infection of an upper respiratory tract
US20030129146A1 (en) * 1997-10-31 2003-07-10 Vincent Fischetti The use of bacterial phage associated lysing proteins for treating bacterial dental caries
US6428784B1 (en) * 1997-10-31 2002-08-06 New Horizons Diagnostics Corp Vaginal suppository for treating group B Streptococcus infection
US6056954A (en) 1997-10-31 2000-05-02 New Horizons Diagnostics Corp Use of bacterial phage associated lysing enzymers for the prophylactic and therapeutic treatment of various illnesses
US20020136712A1 (en) * 1997-10-31 2002-09-26 Fischetti Vincent Bacterial phage associated lysing enzymes for the prophylactic and therapeutic treatment of colonization and infections caused by streptococcus pneumoniae
US20030082110A1 (en) * 1997-10-31 2003-05-01 Vincent Fischetti Use of bacterial phage associated lysing proteins for treating bacterial dental caries
US6406692B1 (en) * 1997-10-31 2002-06-18 New Horizons Diagnostics Corp Composition for treatment of an ocular bacterial infection
US6277399B1 (en) 1997-10-31 2001-08-21 New Horizon Diagnostics Corporation Composition incorporating bacterial phage associated lysing enzymes for treating dermatological infections
US7232576B2 (en) 1997-10-31 2007-06-19 New Horizons Diagnostics Corp Throat lozenge for the treatment of Streptococcus Group A
US6432444B1 (en) 1997-10-31 2002-08-13 New Horizons Diagnostics Corp Use of bacterial phage associated lysing enzymes for treating dermatological infections
US20030129147A1 (en) * 1997-10-31 2003-07-10 Vincent Fischetti Use of bacterial phage associated lysing proteins for treating bacterial dental caries
US6752988B1 (en) 2000-04-28 2004-06-22 New Horizons Diagnostic Corp Method of treating upper resiratory illnesses
GB9724186D0 (en) * 1997-11-14 1998-01-14 British Tech Group Low temperature coatings
DE19820529A1 (de) 1998-05-08 1999-11-11 Lohmann Therapie Syst Lts Wirkstoff enthaltende orale und mucosale Zubereitung mit steuerbarer Wirkstofffreisetzung und ihre Verwendung
US7063837B2 (en) * 1999-09-14 2006-06-20 New Horizons Diagnostics Corp Syrup composition containing phage associated lytic enzymes
US6607748B1 (en) 2000-06-29 2003-08-19 Vincent Lenaerts Cross-linked high amylose starch for use in controlled-release pharmaceutical formulations and processes for its manufacture
EP1174127A1 (en) * 2000-07-21 2002-01-23 Nederlandse Organisatie Voor Toegepast-Natuurwetenschappelijk Onderzoek Tno Composition for targeted release of an actvie substance and process for producing such a composition
WO2002102405A1 (en) * 2000-11-02 2002-12-27 New Horizons Diagnostics Corporation The use of bacterial phage associated lytic enzymes to prevent food poisoning
US20040213765A1 (en) * 2001-07-13 2004-10-28 Vincent Fischetti Use of bacterial phage associated lytic enzymes to prevent food poisoning
EP1684733B1 (en) * 2003-11-21 2011-09-21 Commonwealth Scientific And Industrial Research Organisation G i tract delivery systems
WO2005065291A2 (en) * 2003-12-31 2005-07-21 Genzyme Corporation Enteric coated aliphatic amine polymer bile acid sequestrants
ES2639839T3 (es) * 2004-04-28 2017-10-30 Commonwealth Scientific And Industrial Research Organisation Proceso de tratamiento del almidón
CA2491665A1 (fr) * 2004-12-24 2006-06-24 Louis Cartilier Formulation de comprime pour liberation soutenue de principe actif
GB0607534D0 (en) 2006-04-13 2006-05-24 Univ London Pharmacy Colonic drug delivery formulation
US20100120694A1 (en) 2008-06-04 2010-05-13 Synergy Pharmaceuticals, Inc. Agonists of Guanylate Cyclase Useful for the Treatment of Gastrointestinal Disorders, Inflammation, Cancer and Other Disorders
US8969514B2 (en) 2007-06-04 2015-03-03 Synergy Pharmaceuticals, Inc. Agonists of guanylate cyclase useful for the treatment of hypercholesterolemia, atherosclerosis, coronary heart disease, gallstone, obesity and other cardiovascular diseases
US7879802B2 (en) 2007-06-04 2011-02-01 Synergy Pharmaceuticals Inc. Agonists of guanylate cyclase useful for the treatment of gastrointestinal disorders, inflammation, cancer and other disorders
EP2321341B1 (en) 2008-07-16 2017-02-22 Synergy Pharmaceuticals Inc. Agonists of guanylate cyclase useful for the treatment of gastrointestinal, inflammation, cancer and other disorders
AU2011219788B2 (en) 2010-02-23 2015-05-14 Da Volterra Formulations for oral delivery of adsorbents in the gut
MX2013000024A (es) 2010-07-06 2013-02-01 Gruenenthal Gmbh Nuevas formas de dosificacion gastrorretentivas.
EP2425826A1 (en) 2010-09-01 2012-03-07 Disphar International B.V. Mesalazine tablet having improved dissolution
US9616097B2 (en) 2010-09-15 2017-04-11 Synergy Pharmaceuticals, Inc. Formulations of guanylate cyclase C agonists and methods of use
CN109172816A (zh) 2012-03-29 2019-01-11 塞拉拜姆有限责任公司 在回肠和阑尾上有活性的胃肠位点特异性口服接种疫苗制剂
ES2655622T3 (es) 2012-04-30 2018-02-20 Tillotts Pharma Ag Una formulación de fármaco de liberación retardada
CA2902348C (en) 2013-02-25 2021-11-30 Synergy Pharmaceuticals Inc. Agonists of guanylate cyclase and their uses
RU2015140610A (ru) 2013-03-14 2017-04-17 ТЕРАБАЙОМ, ЭлЭлСи Направленная доставка в желудочно-кишечный тракт пробиотических микроорганизмов и/или терапевтических средств
CA2905435A1 (en) 2013-03-15 2014-09-25 Synergy Pharmaceuticals Inc. Compositions useful for the treatment of gastrointestinal disorders
EP2970384A1 (en) 2013-03-15 2016-01-20 Synergy Pharmaceuticals Inc. Agonists of guanylate cyclase and their uses
EA201690732A1 (ru) 2013-10-10 2016-12-30 Синерджи Фармасьютикалз, Инк. Агонисты гуанилатциклазы, используемые для лечения индуцированных опиоидами дисфункций
NZ717159A (en) 2013-10-29 2019-06-28 Tillotts Pharma Ag A delayed release drug formulation
TW201618783A (zh) 2014-08-07 2016-06-01 艾森塔製藥公司 以布魯頓(Bruton)氏酪胺酸激酶(BTK)佔據和BTK再合成速率為基礎之治療癌症、免疫和自體免疫疾病及發炎性疾病之方法
BR112018006279A2 (pt) 2015-09-29 2018-10-16 ProdrugXtend Pty Ltd nova formulação e métodos de tratamento
WO2017123634A1 (en) 2016-01-11 2017-07-20 Synergy Pharmaceuticals, Inc. Formulations and methods for treating ulcerative colitis
EP3662900A1 (en) 2018-12-07 2020-06-10 Tillotts Pharma AG Colonic drug delivery formulation
EP3662901A1 (en) 2018-12-07 2020-06-10 Tillotts Pharma AG Delayed release drug formulation comprising an outerlayer with an enzymaticyaaly degradable polymer, its composition and its method of manufacturing
EP3662902A1 (en) 2018-12-07 2020-06-10 Tillotts Pharma AG Colonic drug delivery formulation
EP3662898A1 (en) 2018-12-07 2020-06-10 Tillotts Pharma AG Solid composition comprising mesalazine
WO2022101269A1 (en) 2020-11-13 2022-05-19 Da Volterra Formulations and dosage regimen for oral delivery of adsorbents in the gut
WO2024134599A1 (en) 2022-12-21 2024-06-27 Teva Pharmaceutical Industries Ltd. Emptying monitoring system for gastrointestinal tract devices

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1072795A (en) * 1963-08-28 1967-06-21 Eastman Kodak Co Solid composition containing fat-soluble vitamins and processes for making it
US3499962A (en) * 1967-08-24 1970-03-10 Nat Starch Chem Corp Encapsulation of water insoluble materials
BG46154A3 (en) * 1983-02-18 1989-10-16 Warner Lambert Co Method for preparing of capsules
JPS6124516A (ja) * 1984-07-12 1986-02-03 Fujisawa Pharmaceut Co Ltd 持続性錠剤
US4755397A (en) * 1986-12-24 1988-07-05 National Starch And Chemical Corporation Starch based particulate encapsulation process
US4911952A (en) * 1987-07-10 1990-03-27 The United States Of America As Represented By The Secretary Of Agriculture Encapsulation by entrapment within matrix of unmodified starch
KR100585099B1 (ko) * 2003-08-13 2006-05-30 삼성전자주식회사 적층형 메모리 모듈 및 메모리 시스템.

Also Published As

Publication number Publication date
US5108758A (en) 1992-04-28
FI99085B (fi) 1997-06-30
EP0343993A1 (en) 1989-11-29
DE68901494D1 (de) 1992-06-17
NO179274B (no) 1996-06-03
GB8812490D0 (en) 1988-06-29
EP0343993B1 (en) 1992-05-13
FI900410A0 (fi) 1990-01-25
GR3004604T3 (ja) 1993-04-28
DK20290A (da) 1990-01-25
GB2220350B (en) 1991-09-04
DK20290D0 (da) 1990-01-25
ATE75936T1 (de) 1992-05-15
CA1339081C (en) 1997-07-29
WO1989011269A1 (en) 1989-11-30
GB2220350A (en) 1990-01-10
NO179274C (no) 1996-09-11
NO900356L (no) 1990-01-25
FI99085C (fi) 1997-10-10
NO900356D0 (no) 1990-01-25
JP2898036B2 (ja) 1999-05-31
JPH03505448A (ja) 1991-11-28
GB8912048D0 (en) 1989-07-12
ES2037422T3 (es) 1995-04-01

Similar Documents

Publication Publication Date Title
DK175257B1 (da) Formuleringer med forsinket afgivelse, fremgangsmåder til fremstilling af sådanne formuleringer og brug af en forbindelse, der er virksom til behandling af en sygdom i colon
EP0502032B1 (en) Delayed release formulations
EP1030655B1 (en) Low temperature coatings
CN100352509C (zh) 用于控释药物制剂的交联高直链淀粉的淀粉及其制备方法
US20060093668A1 (en) Melt granulated composition and modified release dosage form prepared from said composition
US4970081A (en) Controlled-release, low-dose aspirin formulation and method of treating vascular occlusive disease therewith
JP2001520986A (ja) 放出制御処方
KR20020063978A (ko) 장용성 유산균 미세과립 조성물 및 이의 제조방법
EP0377439B1 (en) Controlled-release, low-dose aspirin
AU671651B2 (en) A drug delivery device and a method of making such device
US20090285863A1 (en) Coating Composition Comprising Starch
CA3111353A1 (en) Controlled drug release formulation
KHAZIM et al. Formulation of probiotics loaded granules of 5-Amino salicylic acid for colon targeting drug delivery system
JPH08143463A (ja) 腸内有用細菌含有錠剤
JPH02174727A (ja) 腸溶性被膜
Bali et al. COMPARATIVE STUDY OF ENTERIC COAT POLYMERS IN DELAYED RELEASE SULFASALAZINE TABLET
CN101495104A (zh) 含有淀粉的包衣组合物

Legal Events

Date Code Title Description
PUP Patent expired