DK175052B1 - Forbedret fremgangsmåde til fremstilling af Amphotericin B liposomer - Google Patents

Forbedret fremgangsmåde til fremstilling af Amphotericin B liposomer Download PDF

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Publication number
DK175052B1
DK175052B1 DK198806293A DK629388A DK175052B1 DK 175052 B1 DK175052 B1 DK 175052B1 DK 198806293 A DK198806293 A DK 198806293A DK 629388 A DK629388 A DK 629388A DK 175052 B1 DK175052 B1 DK 175052B1
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DK
Denmark
Prior art keywords
amphotericin
liposomes
complex
amphiphilic
phospholipid
Prior art date
Application number
DK198806293A
Other languages
Danish (da)
English (en)
Other versions
DK629388D0 (da
DK629388A (da
Inventor
Richard Thomas Proffitt
Jill Adler-Moore
Su-Ming Chiang
Original Assignee
Nexstar Pharmaceuticals Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Nexstar Pharmaceuticals Inc filed Critical Nexstar Pharmaceuticals Inc
Publication of DK629388D0 publication Critical patent/DK629388D0/da
Publication of DK629388A publication Critical patent/DK629388A/da
Application granted granted Critical
Publication of DK175052B1 publication Critical patent/DK175052B1/da

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A61K9/127—Liposomes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A61K9/127—Liposomes
    • A61K9/1277—Processes for preparing; Proliposomes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7042—Compounds having saccharide radicals and heterocyclic rings
    • A61K31/7048—Compounds having saccharide radicals and heterocyclic rings having oxygen as a ring hetero atom, e.g. leucoglucosan, hesperidin, erythromycin, nystatin, digitoxin or digoxin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
    • A61K47/54—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic compound
    • A61K47/543—Lipids, e.g. triglycerides; Polyamines, e.g. spermine or spermidine
    • A61K47/544—Phospholipids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B82—NANOTECHNOLOGY
    • B82Y—SPECIFIC USES OR APPLICATIONS OF NANOSTRUCTURES; MEASUREMENT OR ANALYSIS OF NANOSTRUCTURES; MANUFACTURE OR TREATMENT OF NANOSTRUCTURES
    • B82Y5/00—Nanobiotechnology or nanomedicine, e.g. protein engineering or drug delivery

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Molecular Biology (AREA)
  • Engineering & Computer Science (AREA)
  • Epidemiology (AREA)
  • Nanotechnology (AREA)
  • Biophysics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Dispersion Chemistry (AREA)
  • Communicable Diseases (AREA)
  • Medical Informatics (AREA)
  • Oncology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Biotechnology (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
  • Materials For Medical Uses (AREA)
  • External Artificial Organs (AREA)
  • Manufacturing Of Micro-Capsules (AREA)
DK198806293A 1987-11-12 1988-11-11 Forbedret fremgangsmåde til fremstilling af Amphotericin B liposomer DK175052B1 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US11951887A 1987-11-12 1987-11-12
US11951887 1987-11-12

Publications (3)

Publication Number Publication Date
DK629388D0 DK629388D0 (da) 1988-11-11
DK629388A DK629388A (da) 1989-05-13
DK175052B1 true DK175052B1 (da) 2004-05-10

Family

ID=22384831

Family Applications (1)

Application Number Title Priority Date Filing Date
DK198806293A DK175052B1 (da) 1987-11-12 1988-11-11 Forbedret fremgangsmåde til fremstilling af Amphotericin B liposomer

Country Status (14)

Country Link
US (2) US6770290B1 (no)
EP (1) EP0317120B1 (no)
JP (1) JP2958774B2 (no)
KR (1) KR970007187B1 (no)
AT (1) ATE66598T1 (no)
AU (1) AU598958B2 (no)
CA (1) CA1339008C (no)
DE (1) DE3864495D1 (no)
DK (1) DK175052B1 (no)
ES (1) ES2029330T3 (no)
GR (1) GR3003050T3 (no)
HK (1) HK119893A (no)
IE (1) IE62110B1 (no)
NO (1) NO178484C (no)

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Also Published As

Publication number Publication date
IE883394L (en) 1989-05-12
US5965156A (en) 1999-10-12
HK119893A (en) 1993-11-12
EP0317120A1 (en) 1989-05-24
NO178484C (no) 1996-04-10
DK629388D0 (da) 1988-11-11
KR970007187B1 (ko) 1997-05-07
NO178484B (no) 1996-01-02
JP2958774B2 (ja) 1999-10-06
NO884989L (no) 1989-05-16
KR890007718A (ko) 1989-07-05
NO884989D0 (no) 1988-11-09
IE62110B1 (en) 1994-12-14
DK629388A (da) 1989-05-13
CA1339008C (en) 1997-03-25
AU598958B2 (en) 1990-07-05
GR3003050T3 (en) 1993-02-17
DE3864495D1 (de) 1991-10-02
EP0317120B1 (en) 1991-08-28
US6770290B1 (en) 2004-08-03
ES2029330T3 (es) 1992-08-01
ATE66598T1 (de) 1991-09-15
JPH01160915A (ja) 1989-06-23
AU2416188A (en) 1989-05-18

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