DK172754B1 - 9-R-azacykliske erythromycinantibiotika og farmaceutisk middel indeholdende disse antibiotika - Google Patents
9-R-azacykliske erythromycinantibiotika og farmaceutisk middel indeholdende disse antibiotika Download PDFInfo
- Publication number
- DK172754B1 DK172754B1 DK198902762A DK276289A DK172754B1 DK 172754 B1 DK172754 B1 DK 172754B1 DK 198902762 A DK198902762 A DK 198902762A DK 276289 A DK276289 A DK 276289A DK 172754 B1 DK172754 B1 DK 172754B1
- Authority
- DK
- Denmark
- Prior art keywords
- hydrogen
- erythromycin
- antibiotics
- piperidino
- compound
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H17/00—Compounds containing heterocyclic radicals directly attached to hetero atoms of saccharide radicals
- C07H17/04—Heterocyclic radicals containing only oxygen as ring hetero atoms
- C07H17/08—Hetero rings containing eight or more ring members, e.g. erythromycins
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/075—Ethers or acetals
- A61K31/08—Ethers or acetals acyclic, e.g. paraformaldehyde
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- Genetics & Genomics (AREA)
- Molecular Biology (AREA)
- Biotechnology (AREA)
- Pharmacology & Pharmacy (AREA)
- Biochemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Engineering & Computer Science (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Communicable Diseases (AREA)
- Oncology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Epidemiology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Saccharide Compounds (AREA)
- Cephalosporin Compounds (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US20340088 | 1988-06-07 | ||
US07/203,400 US5075289A (en) | 1988-06-07 | 1988-06-07 | 9-r-azacyclic erythromycin antibiotics |
Publications (3)
Publication Number | Publication Date |
---|---|
DK276289D0 DK276289D0 (da) | 1989-06-06 |
DK276289A DK276289A (da) | 1989-12-08 |
DK172754B1 true DK172754B1 (da) | 1999-06-28 |
Family
ID=22753840
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DK198902762A DK172754B1 (da) | 1988-06-07 | 1989-06-06 | 9-R-azacykliske erythromycinantibiotika og farmaceutisk middel indeholdende disse antibiotika |
Country Status (13)
Country | Link |
---|---|
US (1) | US5075289A (el) |
EP (1) | EP0345627B1 (el) |
JP (1) | JP2922922B2 (el) |
KR (1) | KR0132671B1 (el) |
AT (1) | ATE151772T1 (el) |
AU (1) | AU609307B2 (el) |
CA (1) | CA1328258C (el) |
DE (1) | DE68927967T2 (el) |
DK (1) | DK172754B1 (el) |
ES (1) | ES2103257T3 (el) |
GR (1) | GR3023617T3 (el) |
IL (1) | IL90434A0 (el) |
NZ (1) | NZ229328A (el) |
Families Citing this family (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5217960A (en) * | 1991-05-03 | 1993-06-08 | Abbott Laboratories | Erythromycin derivatives |
EP0549040A1 (en) * | 1991-12-20 | 1993-06-30 | Merck & Co. Inc. | Methods of making 4" derivatives of 9-deoxo-8a-aza-8a-alkyl-8a-homoerythromycin A |
US6436906B1 (en) * | 2001-04-02 | 2002-08-20 | Enanta Pharmaceuticals, Inc. | 9-amino-14-membered macrolides derived from leucomycins |
BRPI0519135A2 (pt) * | 2004-12-21 | 2008-12-23 | Pfizer Prod Inc | macrolÍdeos |
Family Cites Families (37)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
YU31319B (en) * | 1967-08-03 | 1973-04-30 | Pliva Pharm & Chem Works | Postupak za dobijanje acil derivata eritromicin oksima |
US3652537A (en) * | 1969-11-21 | 1972-03-28 | Lilly Co Eli | Epierythromycylamine and epierythromycyl b amine |
GB1341022A (en) * | 1970-04-13 | 1973-12-19 | Lilly Industries Ltd | Erythromycylamine compounds |
ZA71763B (en) * | 1970-04-13 | 1972-03-29 | Lilly Industries Ltd | Erythromycylamines via hydrazones |
US3681322A (en) * | 1970-04-13 | 1972-08-01 | Lilly Co Eli | Adducts of aliphatic and araliphatic aldehydes and erythromycylamine or erythromycyl b amine |
US3660376A (en) * | 1970-09-30 | 1972-05-02 | Lilly Co Eli | N-arylidene erythromycylamines |
GB1345524A (en) * | 1970-09-30 | 1974-01-30 | Lilly Industries Ltd | N-heteroarylidene erythomycylamines |
GB1344629A (en) * | 1970-09-30 | 1974-01-23 | Lilly Industries Ltd | Erythromycin azine derivatives |
US3983103A (en) * | 1973-01-19 | 1976-09-28 | Pliva Pharmaceutical And Chemical Works | N-(Benzenesulfonyl)-erythromycylamine derivatives |
US3923784A (en) * | 1973-09-10 | 1975-12-02 | Hoffmann La Roche | Erythromycin a derivatives |
YU35363B (en) * | 1974-01-14 | 1980-12-31 | Pliva Zagreb | Process for obtaining n-(benzene-sulfonyl)-5-0desosaminyl-erythromycilamine derivatives |
US3992264A (en) * | 1974-02-04 | 1976-11-16 | Hoffmann-La Roche Inc. | Antibiotic 1745A/X and methods for the production thereof |
US3928387A (en) * | 1974-02-04 | 1975-12-23 | Hoffmann La Roche | Antibiotic 1745A/X and methods for the production thereof |
US4070376A (en) * | 1974-02-04 | 1978-01-24 | Hoffmann-La Roche, Inc. | Antibiotic 1745A/X and methods for the production thereof |
DK139522C (da) * | 1975-04-07 | 1979-08-20 | Thomae Gmbh Dr K | Analogifremgangsmaade til fremstilling af 9-iminoalkylamino-erythromyciner eller syreadditionssalte deraf |
AT342770B (de) * | 1975-04-07 | 1978-04-25 | Thomae Gmbh Dr K | Verfahren zur herstellung neuer erythromycinderivate |
DE2750288A1 (de) * | 1977-11-10 | 1979-05-17 | Thomae Gmbh Dr K | Neue 9-(omega-heteroarylamino- alkylamino)-erythromycine, ihre salze, verfahren zu ihrer herstellung und diese enthaltende arzneimittel |
US4180654A (en) * | 1978-01-03 | 1979-12-25 | Pfizer Inc. | 4"-Deoxy-4"-acylamido derivatives of oleandomycin, erythromycin and erythromycin carbonate |
YU43116B (en) * | 1979-04-02 | 1989-04-30 | Pliva Pharm & Chem Works | Process for preparing 11-aza-4-o-cladinosyl-6-o-desosaminyl-15-ethyl-7,13,14-trihydroxy-3,5,7,9,12,14-hexamethyl-oxacyclopentadecane-2-one(11-aza-10-deox |
FR2473525A1 (fr) * | 1980-01-11 | 1981-07-17 | Roussel Uclaf | Nouvelles oximes derivees de l'erythromycine, leur procede de preparation et leur application comme medicaments |
US4283527A (en) * | 1980-04-01 | 1981-08-11 | Pfizer Inc. | Erythromycylamine 11,12-carbonate and derivatives thereof |
FR2534588B2 (fr) * | 1982-10-15 | 1985-09-20 | Roussel Uclaf | Nouvelles oximes derivees de l'erythromycine, leur procede de preparation et leur application comme medicaments |
PH19293A (en) * | 1982-11-15 | 1986-03-04 | Pfizer | Epimeric azahomoerythromycin,pharmaceutical composition containing the same and method of use thereof |
US4492688A (en) * | 1983-11-25 | 1985-01-08 | Pfizer Inc. | Antibacterial cyclic ethers of 9-deoxo-9a-aza-9a-homoerythromycin A and intermediates therefor |
US4465674A (en) * | 1983-09-06 | 1984-08-14 | Pfizer Inc. | Azahomoerythromycin D derivative and intermediates therefor |
GR80277B (en) * | 1983-09-06 | 1985-01-04 | Pfizer | Azahomoerythromycin b derivatives and intermediates therefor |
US4512982A (en) * | 1984-04-13 | 1985-04-23 | Pfizer Inc. | 9α-Aza-9α-homoerythromycin compounds, pharmaceutical composition and therapeutic method |
US4518590A (en) * | 1984-04-13 | 1985-05-21 | Pfizer Inc. | 9α-Aza-9α-homoerythromycin compounds, pharmaceutical compositions and therapeutic method |
GB8421429D0 (en) * | 1984-08-23 | 1984-09-26 | Beecham Group Plc | Chemical compounds |
JPS61103890A (ja) * | 1984-10-26 | 1986-05-22 | Taisho Pharmaceut Co Ltd | 6−0−メチルエリスロマイシンa誘導体 |
DK109886A (da) * | 1985-03-12 | 1986-09-13 | Beecham Group Plc | Erythromycinderivater |
GB8506380D0 (en) * | 1985-03-12 | 1985-04-11 | Beecham Group Plc | Chemical compounds |
US4670549A (en) * | 1985-03-18 | 1987-06-02 | Taisho Pharmaceutical Co., Ltd. | Method for selective methylation of erythromycin a derivatives |
JPS61229895A (ja) * | 1985-04-03 | 1986-10-14 | Nippon Zeon Co Ltd | 保護化デス−n−メチルエリスロマイシン誘導体 |
GB8521402D0 (en) * | 1985-08-28 | 1985-10-02 | Beecham Group Plc | Chemical compounds |
IL81395A0 (en) * | 1986-02-03 | 1987-08-31 | Lilly Co Eli | Novel derivatives of erythromycylamine |
EP0260938B1 (en) * | 1986-09-18 | 1992-12-09 | Taisho Pharmaceutical Co. Ltd | Erythromycin a derivatives and method for preparing the same |
-
1988
- 1988-06-07 US US07/203,400 patent/US5075289A/en not_active Expired - Fee Related
-
1989
- 1989-05-28 IL IL90434A patent/IL90434A0/xx not_active IP Right Cessation
- 1989-05-29 NZ NZ229328A patent/NZ229328A/xx unknown
- 1989-06-01 DE DE68927967T patent/DE68927967T2/de not_active Expired - Fee Related
- 1989-06-01 AT AT89109890T patent/ATE151772T1/de not_active IP Right Cessation
- 1989-06-01 ES ES89109890T patent/ES2103257T3/es not_active Expired - Lifetime
- 1989-06-01 EP EP89109890A patent/EP0345627B1/en not_active Expired - Lifetime
- 1989-06-03 KR KR1019890007655A patent/KR0132671B1/ko not_active IP Right Cessation
- 1989-06-06 DK DK198902762A patent/DK172754B1/da not_active IP Right Cessation
- 1989-06-06 CA CA000601931A patent/CA1328258C/en not_active Expired - Fee Related
- 1989-06-06 JP JP1146556A patent/JP2922922B2/ja not_active Expired - Lifetime
- 1989-06-06 AU AU36102/89A patent/AU609307B2/en not_active Ceased
-
1997
- 1997-05-30 GR GR970401261T patent/GR3023617T3/el unknown
Also Published As
Publication number | Publication date |
---|---|
ATE151772T1 (de) | 1997-05-15 |
EP0345627B1 (en) | 1997-04-16 |
KR0132671B1 (ko) | 1998-04-14 |
JPH0267294A (ja) | 1990-03-07 |
JP2922922B2 (ja) | 1999-07-26 |
DK276289D0 (da) | 1989-06-06 |
GR3023617T3 (en) | 1997-08-29 |
KR910000785A (ko) | 1991-01-29 |
CA1328258C (en) | 1994-04-05 |
DK276289A (da) | 1989-12-08 |
AU609307B2 (en) | 1991-04-26 |
AU3610289A (en) | 1989-12-14 |
US5075289A (en) | 1991-12-24 |
EP0345627A3 (en) | 1991-09-11 |
NZ229328A (en) | 1991-04-26 |
IL90434A0 (en) | 1990-01-18 |
DE68927967D1 (de) | 1997-05-22 |
ES2103257T3 (es) | 1997-09-16 |
EP0345627A2 (en) | 1989-12-13 |
DE68927967T2 (de) | 1997-10-02 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
B1 | Patent granted (law 1993) | ||
PBP | Patent lapsed |
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