DK172057B1 - Fremgangsmåde til fremstilling af multivesikulære liposomer med et biologisk aktivt stof indkapslet deri i nærværelse af et hydrochlorid - Google Patents
Fremgangsmåde til fremstilling af multivesikulære liposomer med et biologisk aktivt stof indkapslet deri i nærværelse af et hydrochlorid Download PDFInfo
- Publication number
- DK172057B1 DK172057B1 DK093988A DK93988A DK172057B1 DK 172057 B1 DK172057 B1 DK 172057B1 DK 093988 A DK093988 A DK 093988A DK 93988 A DK93988 A DK 93988A DK 172057 B1 DK172057 B1 DK 172057B1
- Authority
- DK
- Denmark
- Prior art keywords
- process according
- biologically active
- hydrochloride
- aqueous
- lipid
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/10—Dispersions; Emulsions
- A61K9/127—Liposomes
- A61K9/1277—Processes for preparing; Proliposomes
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Dispersion Chemistry (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Manufacturing Of Micro-Capsules (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB878704171A GB8704171D0 (en) | 1987-02-23 | 1987-02-23 | Multivesicular liposomes |
| GB8704171 | 1987-02-23 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| DK93988D0 DK93988D0 (da) | 1988-02-23 |
| DK93988A DK93988A (da) | 1988-08-24 |
| DK172057B1 true DK172057B1 (da) | 1997-10-06 |
Family
ID=10612750
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK093988A DK172057B1 (da) | 1987-02-23 | 1988-02-23 | Fremgangsmåde til fremstilling af multivesikulære liposomer med et biologisk aktivt stof indkapslet deri i nærværelse af et hydrochlorid |
Country Status (18)
| Country | Link |
|---|---|
| EP (1) | EP0280503B9 (fi) |
| JP (1) | JP2843566B2 (fi) |
| KR (1) | KR970004907B1 (fi) |
| AT (1) | ATE87823T1 (fi) |
| AU (1) | AU602190B2 (fi) |
| CA (1) | CA1323568C (fi) |
| DE (1) | DE3879987T2 (fi) |
| DK (1) | DK172057B1 (fi) |
| ES (1) | ES2053722T4 (fi) |
| FI (1) | FI95439C (fi) |
| GB (1) | GB8704171D0 (fi) |
| GR (1) | GR3007581T3 (fi) |
| IE (1) | IE62221B1 (fi) |
| IL (1) | IL85509A (fi) |
| NO (1) | NO174087C (fi) |
| NZ (1) | NZ223599A (fi) |
| PT (1) | PT86805B (fi) |
| ZA (1) | ZA881241B (fi) |
Families Citing this family (24)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA2033714A1 (en) * | 1990-01-25 | 1991-07-26 | Alberto Ferro | Pharmaceutical preparations |
| NZ237464A (en) * | 1990-03-21 | 1995-02-24 | Depotech Corp | Liposomes with at least two separate chambers encapsulating two separate biologically active substances |
| DE4122661C2 (de) * | 1990-08-06 | 1996-07-11 | Nattermann A & Cie | Pharmazeutisches Produkt zur Behandlung von Pneumocystis-carinii-Pneumonie |
| DE4108902A1 (de) * | 1990-08-06 | 1992-02-13 | Nattermann A & Cie | Wasserhaltiges liposomensystem |
| ES2041597B1 (es) * | 1992-05-05 | 1994-06-01 | Bazaco Joan Freixas | Nuevo procedimiento para la preparacion de liposomas que encapsulan productos farmaceuticos y cosmeticos. |
| US5759573A (en) * | 1993-04-22 | 1998-06-02 | Depotech Corporation | Cyclodextrin liposomes encapsulating pharmacologic compounds and methods for their use |
| PL314485A1 (en) * | 1993-11-16 | 1996-09-16 | Depotech Corp | Bubbles with controllable release of active substances |
| US5993850A (en) * | 1994-09-13 | 1999-11-30 | Skyepharma Inc. | Preparation of multivesicular liposomes for controlled release of encapsulated biologically active substances |
| US5931809A (en) * | 1995-07-14 | 1999-08-03 | Depotech Corporation | Epidural administration of therapeutic compounds with sustained rate of release |
| US6306432B1 (en) * | 1997-09-08 | 2001-10-23 | Chiron Corporation | High and low load formulations of IGF-I in multivesicular liposomes |
| DK1014946T3 (da) * | 1997-09-18 | 2010-06-28 | Pacira Pharmaceuticals Inc | Liposomale anæstetiske sammensætninger med forsinket frigivelse |
| JP4575592B2 (ja) | 1997-11-14 | 2010-11-04 | パシラ ファーマシューティカルズ インコーポレーテッド | 多小胞リポソームの製造 |
| PT1180017E (pt) | 1999-05-27 | 2010-05-28 | Euro Celtique Sa | Preparações com povidona-iodo para o tratamento de feridas |
| US7300667B1 (en) | 1999-05-27 | 2007-11-27 | Euro-Celtique, S.A. | Preparations for the application of anti-inflammatory, especially antiseptic agents and/or agents promoting the healing of wounds, to the lower respiratory tract |
| CN101190183B (zh) * | 2006-11-29 | 2010-05-12 | 上海医药工业研究院 | 一种盐酸可乐定多泡脂质体及其制备方法 |
| US9107970B2 (en) | 2008-07-15 | 2015-08-18 | Bror Morein | Method and a filter for capturing airborne agents |
| ITBO20090012A1 (it) * | 2009-01-15 | 2010-07-16 | Vincenza Dolo | Composizione biocida e suo uso. |
| EP2813220A3 (en) | 2010-04-09 | 2015-06-17 | Pacira Pharmaceuticals, Inc. | Method for formulating large diameter synthetic membrane vesicles |
| US9770414B2 (en) * | 2010-05-13 | 2017-09-26 | Pacira Pharmaceuticals, Inc. | Sustained release formulation of methotrexate as a disease-modifying antirheumatic drug (DMARD) and an anti-cancer agent |
| US10610486B2 (en) | 2010-10-28 | 2020-04-07 | Pacira Pharmaceuticals, Inc. | Sustained release formulation of a non-steroidal anti-inflammatory drug |
| CN109983013A (zh) | 2016-11-18 | 2019-07-05 | 帕西拉制药有限公司 | 美洛昔康锌复合物微粒多囊脂质体制剂及其制备方法 |
| US11357727B1 (en) | 2021-01-22 | 2022-06-14 | Pacira Pharmaceuticals, Inc. | Manufacturing of bupivacaine multivesicular liposomes |
| US11033495B1 (en) | 2021-01-22 | 2021-06-15 | Pacira Pharmaceuticals, Inc. | Manufacturing of bupivacaine multivesicular liposomes |
| US11278494B1 (en) | 2021-01-22 | 2022-03-22 | Pacira Pharmaceuticals, Inc. | Manufacturing of bupivacaine multivesicular liposomes |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CH624011A5 (fi) * | 1977-08-05 | 1981-07-15 | Battelle Memorial Institute |
-
1987
- 1987-02-23 GB GB878704171A patent/GB8704171D0/en active Pending
-
1988
- 1988-02-22 NO NO880768A patent/NO174087C/no not_active IP Right Cessation
- 1988-02-23 AT AT88301512T patent/ATE87823T1/de not_active IP Right Cessation
- 1988-02-23 DK DK093988A patent/DK172057B1/da not_active IP Right Cessation
- 1988-02-23 ZA ZA881241A patent/ZA881241B/xx unknown
- 1988-02-23 JP JP63040522A patent/JP2843566B2/ja not_active Expired - Lifetime
- 1988-02-23 EP EP88301512A patent/EP0280503B9/en not_active Expired - Lifetime
- 1988-02-23 ES ES88301512T patent/ES2053722T4/es not_active Expired - Lifetime
- 1988-02-23 DE DE8888301512T patent/DE3879987T2/de not_active Expired - Lifetime
- 1988-02-23 CA CA000559596A patent/CA1323568C/en not_active Expired - Lifetime
- 1988-02-23 NZ NZ223599A patent/NZ223599A/xx unknown
- 1988-02-23 IL IL85509A patent/IL85509A/xx not_active IP Right Cessation
- 1988-02-23 KR KR1019880001859A patent/KR970004907B1/ko not_active IP Right Cessation
- 1988-02-23 PT PT86805A patent/PT86805B/pt not_active IP Right Cessation
- 1988-02-23 FI FI880841A patent/FI95439C/fi active IP Right Grant
- 1988-02-23 AU AU12055/88A patent/AU602190B2/en not_active Expired
- 1988-02-23 IE IE48688A patent/IE62221B1/en not_active IP Right Cessation
-
1993
- 1993-04-08 GR GR930400190T patent/GR3007581T3/el unknown
Also Published As
| Publication number | Publication date |
|---|---|
| NO174087B (no) | 1993-12-06 |
| JP2843566B2 (ja) | 1999-01-06 |
| FI880841A (fi) | 1988-08-24 |
| NZ223599A (en) | 1990-09-26 |
| FI880841A0 (fi) | 1988-02-23 |
| KR890012638A (ko) | 1989-09-18 |
| DE3879987D1 (de) | 1993-05-13 |
| ZA881241B (en) | 1988-08-23 |
| DK93988A (da) | 1988-08-24 |
| NO880768D0 (no) | 1988-02-22 |
| AU1205588A (en) | 1988-08-25 |
| CA1323568C (en) | 1993-10-26 |
| JPH01125318A (ja) | 1989-05-17 |
| FI95439B (fi) | 1995-10-31 |
| ES2053722T3 (es) | 1994-08-01 |
| DK93988D0 (da) | 1988-02-23 |
| IE62221B1 (en) | 1995-01-11 |
| PT86805A (pt) | 1988-03-01 |
| GB8704171D0 (en) | 1987-04-01 |
| GR3007581T3 (fi) | 1993-08-31 |
| IL85509A0 (en) | 1988-08-31 |
| NO880768L (no) | 1988-08-24 |
| NO174087C (no) | 1994-03-16 |
| EP0280503B1 (en) | 1993-04-07 |
| EP0280503B9 (en) | 2004-04-21 |
| FI95439C (fi) | 1996-02-12 |
| AU602190B2 (en) | 1990-10-04 |
| KR970004907B1 (ko) | 1997-04-08 |
| DE3879987T2 (de) | 1993-07-15 |
| PT86805B (pt) | 1992-05-29 |
| EP0280503A3 (en) | 1989-10-11 |
| ATE87823T1 (de) | 1993-04-15 |
| IL85509A (en) | 1992-03-29 |
| ES2053722T4 (es) | 2004-06-01 |
| EP0280503A2 (en) | 1988-08-31 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| B1 | Patent granted (law 1993) | ||
| PUP | Patent expired |