DK1713801T3 - Fremgangsmåde til fremstilling af 1-(2S,3S)-2-benzhydryl-N-(5-tert-butyl-2-methoxybenzyl)quinuclidin-3-amin - Google Patents
Fremgangsmåde til fremstilling af 1-(2S,3S)-2-benzhydryl-N-(5-tert-butyl-2-methoxybenzyl)quinuclidin-3-aminInfo
- Publication number
- DK1713801T3 DK1713801T3 DK05702373T DK05702373T DK1713801T3 DK 1713801 T3 DK1713801 T3 DK 1713801T3 DK 05702373 T DK05702373 T DK 05702373T DK 05702373 T DK05702373 T DK 05702373T DK 1713801 T3 DK1713801 T3 DK 1713801T3
- Authority
- DK
- Denmark
- Prior art keywords
- quinuclidin
- benzhydryl
- methoxybenzyl
- tert
- amine
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D453/00—Heterocyclic compounds containing quinuclidine or iso-quinuclidine ring systems, e.g. quinine alkaloids
- C07D453/02—Heterocyclic compounds containing quinuclidine or iso-quinuclidine ring systems, e.g. quinine alkaloids containing not further condensed quinuclidine ring systems
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US54132304P | 2004-02-02 | 2004-02-02 | |
| PCT/IB2005/000221 WO2005075473A1 (en) | 2004-02-02 | 2005-01-26 | Process for preparation of 1-(2s,3s)-2-benzhydr yl-n-(5-tert-butyl-2-methoxybenzyl)quinuclidin-3-amine |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DK1713801T3 true DK1713801T3 (da) | 2008-03-17 |
Family
ID=34837478
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK05702373T DK1713801T3 (da) | 2004-02-02 | 2005-01-26 | Fremgangsmåde til fremstilling af 1-(2S,3S)-2-benzhydryl-N-(5-tert-butyl-2-methoxybenzyl)quinuclidin-3-amin |
Country Status (22)
| Country | Link |
|---|---|
| US (1) | US20090099364A1 (de) |
| EP (1) | EP1713801B1 (de) |
| JP (1) | JP2007519710A (de) |
| KR (1) | KR100812046B1 (de) |
| CN (1) | CN1914202A (de) |
| AR (1) | AR047523A1 (de) |
| AT (1) | ATE380811T1 (de) |
| AU (1) | AU2005210259A1 (de) |
| BR (1) | BRPI0507334A (de) |
| CA (1) | CA2554360A1 (de) |
| CY (1) | CY1107141T1 (de) |
| DE (1) | DE602005003791T2 (de) |
| DK (1) | DK1713801T3 (de) |
| ES (1) | ES2296131T3 (de) |
| IL (1) | IL176817A0 (de) |
| NO (1) | NO20063268L (de) |
| PL (1) | PL1713801T3 (de) |
| PT (1) | PT1713801E (de) |
| RU (1) | RU2320659C9 (de) |
| SI (1) | SI1713801T1 (de) |
| WO (1) | WO2005075473A1 (de) |
| ZA (1) | ZA200605784B (de) |
Families Citing this family (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101090735A (zh) | 2004-01-30 | 2007-12-19 | 辉瑞产品有限公司 | 用于使用液体剂型用β－环糊精制备多剂量制剂的抗菌防腐剂 |
| EP2571847B1 (de) | 2010-05-19 | 2016-09-21 | Sandoz AG | Verfahren zur herstellung chiraler hydrazide |
| WO2011144657A1 (en) | 2010-05-19 | 2011-11-24 | Sandoz Ag | Purification of posaconazole and posaconazole intermediates |
| RU2580318C2 (ru) | 2010-05-19 | 2016-04-10 | Сандоз Аг | Получение промежуточных продуктов для синтеза позаконазола |
| US9446029B2 (en) | 2010-07-27 | 2016-09-20 | Colorado State University Research Foundation | Use of NK-1 receptor antagonists in management of visceral pain |
| DE102011100534A1 (de) | 2011-05-05 | 2012-11-08 | Howaldtswerke-Deutsche Werft Gmbh | Verfahren zum Betreiben einer Reformer-Brennstoffzellenanlage |
| CN103635465A (zh) | 2011-06-16 | 2014-03-12 | 桑多斯股份公司 | 制备手性化合物的方法 |
| CN108341812A (zh) * | 2017-01-23 | 2018-07-31 | 科贝源(北京)生物医药科技有限公司 | 一种含奎宁环化合物的制备方法 |
| CN108341811A (zh) * | 2017-01-23 | 2018-07-31 | 科贝源(北京)生物医药科技有限公司 | 马罗皮坦杂质的制备方法 |
| CN106977512B (zh) * | 2017-05-04 | 2019-01-01 | 海门慧聚药业有限公司 | 制备马罗匹坦游离碱的方法 |
| CN110577522B (zh) * | 2018-06-07 | 2022-12-27 | 东莞市东阳光动物保健药品有限公司 | 马罗匹坦柠檬酸盐新晶型及其制备方法 |
| CN109320510B (zh) * | 2018-11-27 | 2021-04-27 | 江苏慧聚药业有限公司 | 一种马罗匹坦游离碱的制备方法 |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO1992021677A1 (en) | 1991-05-31 | 1992-12-10 | Pfizer Inc. | bibNUCLIDINE DERIVATIVES |
| US5393762A (en) * | 1993-06-04 | 1995-02-28 | Pfizer Inc. | Pharmaceutical agents for treatment of emesis |
| PE8798A1 (es) * | 1995-07-17 | 1998-03-02 | Pfizer | Procedimiento de separacion de los enantiomeros del 1-azabiciclo[2.2.2] octan-3-amina, 2-(difenilmetil) -n- [[2-metoxi-5-(1-metiletil) fenil] metil] |
| US6255320B1 (en) * | 1999-06-01 | 2001-07-03 | Pfizer Inc. | Polymorphs of a crystalline azo-bicyclo (2,2,2) octan-3-amine citrate and their pharmaceutical compositions |
| US6861526B2 (en) * | 2002-10-16 | 2005-03-01 | Pfizer Inc. | Process for the preparation of (S,S)-cis-2-benzhydryl-3-benzylaminoquinuclidine |
-
2005
- 2005-01-26 US US10/588,049 patent/US20090099364A1/en not_active Abandoned
- 2005-01-26 ES ES05702373T patent/ES2296131T3/es active Active
- 2005-01-26 AU AU2005210259A patent/AU2005210259A1/en not_active Abandoned
- 2005-01-26 EP EP05702373A patent/EP1713801B1/de active Active
- 2005-01-26 BR BRPI0507334-0A patent/BRPI0507334A/pt not_active IP Right Cessation
- 2005-01-26 PL PL05702373T patent/PL1713801T3/pl unknown
- 2005-01-26 DK DK05702373T patent/DK1713801T3/da active
- 2005-01-26 AT AT05702373T patent/ATE380811T1/de not_active IP Right Cessation
- 2005-01-26 RU RU2006127969/04A patent/RU2320659C9/ru not_active IP Right Cessation
- 2005-01-26 DE DE602005003791T patent/DE602005003791T2/de not_active Expired - Fee Related
- 2005-01-26 PT PT05702373T patent/PT1713801E/pt unknown
- 2005-01-26 KR KR1020067015573A patent/KR100812046B1/ko not_active IP Right Cessation
- 2005-01-26 SI SI200530124T patent/SI1713801T1/sl unknown
- 2005-01-26 CN CNA2005800038987A patent/CN1914202A/zh active Pending
- 2005-01-26 JP JP2006550351A patent/JP2007519710A/ja not_active Withdrawn
- 2005-01-26 CA CA002554360A patent/CA2554360A1/en not_active Abandoned
- 2005-01-26 WO PCT/IB2005/000221 patent/WO2005075473A1/en active IP Right Grant
- 2005-01-31 AR ARP050100351A patent/AR047523A1/es not_active Application Discontinuation
-
2006
- 2006-07-12 IL IL176817A patent/IL176817A0/en unknown
- 2006-07-13 NO NO20063268A patent/NO20063268L/no not_active Application Discontinuation
- 2006-07-13 ZA ZA200605784A patent/ZA200605784B/en unknown
-
2008
- 2008-01-15 CY CY20081100055T patent/CY1107141T1/el unknown
Also Published As
| Publication number | Publication date |
|---|---|
| NO20063268L (no) | 2006-08-15 |
| ES2296131T3 (es) | 2008-04-16 |
| EP1713801B1 (de) | 2007-12-12 |
| CY1107141T1 (el) | 2012-10-24 |
| US20090099364A1 (en) | 2009-04-16 |
| SI1713801T1 (sl) | 2008-04-30 |
| CA2554360A1 (en) | 2005-08-18 |
| RU2320659C1 (ru) | 2008-03-27 |
| KR20060127966A (ko) | 2006-12-13 |
| DE602005003791D1 (de) | 2008-01-24 |
| PL1713801T3 (pl) | 2008-04-30 |
| DE602005003791T2 (de) | 2008-05-29 |
| CN1914202A (zh) | 2007-02-14 |
| EP1713801A1 (de) | 2006-10-25 |
| RU2320659C9 (ru) | 2008-07-20 |
| AR047523A1 (es) | 2006-01-25 |
| JP2007519710A (ja) | 2007-07-19 |
| AU2005210259A1 (en) | 2005-08-18 |
| BRPI0507334A (pt) | 2007-07-03 |
| PT1713801E (pt) | 2008-02-11 |
| WO2005075473A1 (en) | 2005-08-18 |
| IL176817A0 (en) | 2006-10-31 |
| ZA200605784B (en) | 2007-11-28 |
| ATE380811T1 (de) | 2007-12-15 |
| KR100812046B1 (ko) | 2008-03-10 |
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