DK1707568T3 - Farmaceutisk sammensætning til anvendelse i behandlingen af ovariecancer hos et menneske, der har sygdommen - Google Patents

Farmaceutisk sammensætning til anvendelse i behandlingen af ovariecancer hos et menneske, der har sygdommen

Info

Publication number
DK1707568T3
DK1707568T3 DK05076845.6T DK05076845T DK1707568T3 DK 1707568 T3 DK1707568 T3 DK 1707568T3 DK 05076845 T DK05076845 T DK 05076845T DK 1707568 T3 DK1707568 T3 DK 1707568T3
Authority
DK
Denmark
Prior art keywords
pharmaceutical composition
human
topotecan
treatment
ovarian cancer
Prior art date
Application number
DK05076845.6T
Other languages
English (en)
Inventor
Randall Keith Johnson
Original Assignee
Glaxosmithkline Llc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Glaxosmithkline Llc filed Critical Glaxosmithkline Llc
Application granted granted Critical
Publication of DK1707568T3 publication Critical patent/DK1707568T3/da

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/535—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one oxygen as the ring hetero atoms, e.g. 1,2-oxazines
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
    • C07D491/12—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains three hetero rings
    • C07D491/16—Peri-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47—Quinolines; Isoquinolines
    • A61K31/4738—Quinolines; Isoquinolines ortho- or peri-condensed with heterocyclic ring systems
    • A61K31/4741—Quinolines; Isoquinolines ortho- or peri-condensed with heterocyclic ring systems condensed with ring systems having oxygen as a ring hetero atom, e.g. tubocuraran derivatives, noscapine, bicuculline
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47—Quinolines; Isoquinolines
    • A61K31/4738—Quinolines; Isoquinolines ortho- or peri-condensed with heterocyclic ring systems
    • A61K31/4745—Quinolines; Isoquinolines ortho- or peri-condensed with heterocyclic ring systems condensed with ring systems having nitrogen as a ring hetero atom, e.g. phenantrolines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
    • C07D491/22—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains four or more hetero rings
DK05076845.6T 1991-02-21 1992-02-07 Farmaceutisk sammensætning til anvendelse i behandlingen af ovariecancer hos et menneske, der har sygdommen DK1707568T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US65894891A 1991-02-21 1991-02-21
EP92907833A EP0572557B1 (en) 1991-02-21 1992-02-07 Use of topotecan in the manufacture of a medicament for use in the treatment of ovarian cancer

Publications (1)

Publication Number Publication Date
DK1707568T3 true DK1707568T3 (da) 2010-11-08

Family

ID=24643386

Family Applications (2)

Application Number Title Priority Date Filing Date
DK05076845.6T DK1707568T3 (da) 1991-02-21 1992-02-07 Farmaceutisk sammensætning til anvendelse i behandlingen af ovariecancer hos et menneske, der har sygdommen
DK92907833.5T DK0572557T3 (da) 1991-02-21 1992-02-07 Anvendelse af topotecan til fremstilling af et lægemiddel til anvendelse ved behandling af kræft i æggestokkene

Family Applications After (1)

Application Number Title Priority Date Filing Date
DK92907833.5T DK0572557T3 (da) 1991-02-21 1992-02-07 Anvendelse af topotecan til fremstilling af et lægemiddel til anvendelse ved behandling af kræft i æggestokkene

Country Status (13)

Country Link
EP (3) EP1690542A3 (da)
JP (1) JP2778632B2 (da)
KR (1) KR930702983A (da)
AT (2) ATE444755T1 (da)
AU (1) AU663312B2 (da)
CA (1) CA2103708C (da)
DE (2) DE69233773D1 (da)
DK (2) DK1707568T3 (da)
ES (2) ES2334178T3 (da)
HK (1) HK1012265A1 (da)
MX (1) MX9200754A (da)
PT (1) PT100156B (da)
WO (1) WO1992014469A1 (da)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101255406B (zh) * 2005-04-22 2010-05-26 李红霞 人卵巢癌耐药细胞株
ES2371171B1 (es) * 2010-06-08 2012-11-16 Consejo Superior De Investigaciones Científicas (Csic) Derivados de camptotecina como agentes antitumorales.
CN102477042A (zh) * 2010-11-26 2012-05-30 复旦大学 10-羟基喜树碱衍生物及其制备方法和用途

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5004758A (en) 1987-12-01 1991-04-02 Smithkline Beecham Corporation Water soluble camptothecin analogs useful for inhibiting the growth of animal tumor cells

Also Published As

Publication number Publication date
ES2334178T3 (es) 2010-03-05
HK1012265A1 (en) 1999-07-30
ATE476182T1 (de) 2010-08-15
EP0572557B1 (en) 2009-10-07
PT100156A (pt) 1993-05-31
CA2103708A1 (en) 1992-08-22
ATE444755T1 (de) 2009-10-15
ES2349037T3 (es) 2010-12-22
AU1461692A (en) 1992-09-15
WO1992014469A1 (en) 1992-09-03
EP1707568A2 (en) 2006-10-04
EP0572557A1 (en) 1993-12-08
EP1690542A2 (en) 2006-08-16
MX9200754A (es) 1992-08-01
EP1707568B1 (en) 2010-08-04
JP2778632B2 (ja) 1998-07-23
KR930702983A (ko) 1993-11-29
PT100156B (pt) 1999-09-30
DE69233773D1 (de) 2009-11-19
EP1707568A3 (en) 2008-03-26
DE69233793D1 (de) 2010-09-16
EP0572557A4 (en) 1993-12-29
JPH06505740A (ja) 1994-06-30
EP1690542A3 (en) 2008-03-26
DK0572557T3 (da) 2010-02-01
AU663312B2 (en) 1995-10-05
CA2103708C (en) 2004-04-27

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