HK1012265A1 - Use of topotecan in the manufacture of a medicament for use in the treatment of ovarian cancer - Google Patents

Use of topotecan in the manufacture of a medicament for use in the treatment of ovarian cancer

Info

Publication number
HK1012265A1
HK1012265A1 HK98113535.8A HK98113535A HK1012265A1 HK 1012265 A1 HK1012265 A1 HK 1012265A1 HK 98113535 A HK98113535 A HK 98113535A HK 1012265 A1 HK1012265 A1 HK 1012265A1
Authority
HK
Hong Kong
Prior art keywords
topotecan
treatment
ovarian cancer
pharmaceutical composition
human
Prior art date
Application number
HK98113535.8A
Other languages
English (en)
Inventor
Randall Keith Johnson
Original Assignee
Smithkline Beecham Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Smithkline Beecham Corp filed Critical Smithkline Beecham Corp
Publication of HK1012265A1 publication Critical patent/HK1012265A1/xx

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/535—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one oxygen as the ring hetero atoms, e.g. 1,2-oxazines
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
    • C07D491/12—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains three hetero rings
    • C07D491/16—Peri-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47—Quinolines; Isoquinolines
    • A61K31/4738—Quinolines; Isoquinolines ortho- or peri-condensed with heterocyclic ring systems
    • A61K31/4741—Quinolines; Isoquinolines ortho- or peri-condensed with heterocyclic ring systems condensed with ring systems having oxygen as a ring hetero atom, e.g. tubocuraran derivatives, noscapine, bicuculline
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47—Quinolines; Isoquinolines
    • A61K31/4738—Quinolines; Isoquinolines ortho- or peri-condensed with heterocyclic ring systems
    • A61K31/4745—Quinolines; Isoquinolines ortho- or peri-condensed with heterocyclic ring systems condensed with ring systems having nitrogen as a ring hetero atom, e.g. phenantrolines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
    • C07D491/22—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains four or more hetero rings
HK98113535.8A 1991-02-21 1998-12-15 Use of topotecan in the manufacture of a medicament for use in the treatment of ovarian cancer HK1012265A1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US65894891A 1991-02-21 1991-02-21
PCT/US1992/001028 WO1992014469A1 (en) 1991-02-21 1992-02-07 Treatment of ovarian cancer

Publications (1)

Publication Number Publication Date
HK1012265A1 true HK1012265A1 (en) 1999-07-30

Family

ID=24643386

Family Applications (1)

Application Number Title Priority Date Filing Date
HK98113535.8A HK1012265A1 (en) 1991-02-21 1998-12-15 Use of topotecan in the manufacture of a medicament for use in the treatment of ovarian cancer

Country Status (13)

Country Link
EP (3) EP1690542A3 (xx)
JP (1) JP2778632B2 (xx)
KR (1) KR930702983A (xx)
AT (2) ATE444755T1 (xx)
AU (1) AU663312B2 (xx)
CA (1) CA2103708C (xx)
DE (2) DE69233793D1 (xx)
DK (2) DK0572557T3 (xx)
ES (2) ES2334178T3 (xx)
HK (1) HK1012265A1 (xx)
MX (1) MX9200754A (xx)
PT (1) PT100156B (xx)
WO (1) WO1992014469A1 (xx)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101255406B (zh) * 2005-04-22 2010-05-26 李红霞 人卵巢癌耐药细胞株
ES2371171B1 (es) * 2010-06-08 2012-11-16 Consejo Superior De Investigaciones Científicas (Csic) Derivados de camptotecina como agentes antitumorales.
CN102477042A (zh) * 2010-11-26 2012-05-30 复旦大学 10-羟基喜树碱衍生物及其制备方法和用途

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5004758A (en) 1987-12-01 1991-04-02 Smithkline Beecham Corporation Water soluble camptothecin analogs useful for inhibiting the growth of animal tumor cells

Also Published As

Publication number Publication date
DE69233773D1 (de) 2009-11-19
EP1707568B1 (en) 2010-08-04
JP2778632B2 (ja) 1998-07-23
EP1707568A3 (en) 2008-03-26
ES2349037T3 (es) 2010-12-22
PT100156B (pt) 1999-09-30
AU1461692A (en) 1992-09-15
EP0572557A4 (en) 1993-12-29
MX9200754A (es) 1992-08-01
EP1690542A3 (en) 2008-03-26
DK0572557T3 (da) 2010-02-01
CA2103708A1 (en) 1992-08-22
AU663312B2 (en) 1995-10-05
ATE444755T1 (de) 2009-10-15
EP0572557B1 (en) 2009-10-07
DE69233793D1 (de) 2010-09-16
CA2103708C (en) 2004-04-27
JPH06505740A (ja) 1994-06-30
EP1690542A2 (en) 2006-08-16
KR930702983A (ko) 1993-11-29
PT100156A (pt) 1993-05-31
WO1992014469A1 (en) 1992-09-03
EP0572557A1 (en) 1993-12-08
DK1707568T3 (da) 2010-11-08
ES2334178T3 (es) 2010-03-05
EP1707568A2 (en) 2006-10-04
ATE476182T1 (de) 2010-08-15

Similar Documents

Publication Publication Date Title
HK1012268A1 (en) Composition containing cisplatin and topotecan as antitumor agent
AU704393C (en) Methods for administration of taxol
AU8696191A (en) Formulations and their use in the treatment of neurological diseases
IL103303A (en) Pharmaceutical compositions containing ibuprofen and codeine for relief of chronic pain
EP0396616A4 (en) Reduction of side effects of cancer therapy
AU693833B2 (en) Products containing G-CSF and TNF binding protein
AU1412088A (en) Therapeutic nucleosides
HK1005847A1 (en) Use of acetyl l-carnitine in the therapeutic treatment of coma
EP0584034A3 (en) Conjugates of cytotoxic drugs for the treatment of neoplastic diseases.
HK1012265A1 (en) Use of topotecan in the manufacture of a medicament for use in the treatment of ovarian cancer
GB8816760D0 (en) Therapeutic compounds
MY111746A (en) Therapeutic nucleosides.
AU7703491A (en) Novel application of 4-carbamoyl-1-beta-d-ribofuranosyl imidazolium-5-olate
GB8819626D0 (en) Pharmaceutical composition for treatment of tumours
PT1250926E (pt) Utilização de uma s-camptotecina insolúvel em água, com um anel de lactona fechado, no fabrico de um medicamento para o tratamento do cancro do cólon
OA09790A (en) "Paromomycin or its derivatives or salts thereof for parenteral treatment of human parasitic diseases".

Legal Events

Date Code Title Description
PE Patent expired

Effective date: 20120206