PT100156A - Uso de compostos analogos da camptotecina na obtencao de um medicamento para uso no tratamento do cancro do ovario e composicoes farmaceuticas - Google Patents

Uso de compostos analogos da camptotecina na obtencao de um medicamento para uso no tratamento do cancro do ovario e composicoes farmaceuticas

Info

Publication number
PT100156A
PT100156A PT100156A PT10015692A PT100156A PT 100156 A PT100156 A PT 100156A PT 100156 A PT100156 A PT 100156A PT 10015692 A PT10015692 A PT 10015692A PT 100156 A PT100156 A PT 100156A
Authority
PT
Portugal
Prior art keywords
treatment
topotecan
camptotecin
medication
pharmaceutical composition
Prior art date
Application number
PT100156A
Other languages
English (en)
Other versions
PT100156B (pt
Inventor
Randall Keith Johnson
Original Assignee
Smithkline Beecham Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Smithkline Beecham Corp filed Critical Smithkline Beecham Corp
Publication of PT100156A publication Critical patent/PT100156A/pt
Publication of PT100156B publication Critical patent/PT100156B/pt

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/535Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one oxygen as the ring hetero atoms, e.g. 1,2-oxazines
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D491/00Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
    • C07D491/12Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains three hetero rings
    • C07D491/16Peri-condensed systems
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44Non condensed pyridines; Hydrogenated derivatives thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47Quinolines; Isoquinolines
    • A61K31/4738Quinolines; Isoquinolines ortho- or peri-condensed with heterocyclic ring systems
    • A61K31/4741Quinolines; Isoquinolines ortho- or peri-condensed with heterocyclic ring systems condensed with ring systems having oxygen as a ring hetero atom, e.g. tubocuraran derivatives, noscapine, bicuculline
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47Quinolines; Isoquinolines
    • A61K31/4738Quinolines; Isoquinolines ortho- or peri-condensed with heterocyclic ring systems
    • A61K31/4745Quinolines; Isoquinolines ortho- or peri-condensed with heterocyclic ring systems condensed with ring systems having nitrogen as a ring hetero atom, e.g. phenantrolines
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D491/00Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
    • C07D491/22Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains four or more hetero rings

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Epidemiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Steroid Compounds (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Medicines Containing Plant Substances (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Polysaccharides And Polysaccharide Derivatives (AREA)
PT100156A 1991-02-21 1992-02-21 Uso de compostos analogos da camptotecina na obtencao de um medicamento para uso no tratamento do cancro do ovario e composicoes farmaceuticas PT100156B (pt)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US65894891A 1991-02-21 1991-02-21

Publications (2)

Publication Number Publication Date
PT100156A true PT100156A (pt) 1993-05-31
PT100156B PT100156B (pt) 1999-09-30

Family

ID=24643386

Family Applications (1)

Application Number Title Priority Date Filing Date
PT100156A PT100156B (pt) 1991-02-21 1992-02-21 Uso de compostos analogos da camptotecina na obtencao de um medicamento para uso no tratamento do cancro do ovario e composicoes farmaceuticas

Country Status (13)

Country Link
EP (3) EP1690542A3 (pt)
JP (1) JP2778632B2 (pt)
KR (1) KR930702983A (pt)
AT (2) ATE476182T1 (pt)
AU (1) AU663312B2 (pt)
CA (1) CA2103708C (pt)
DE (2) DE69233773D1 (pt)
DK (2) DK0572557T3 (pt)
ES (2) ES2349037T3 (pt)
HK (1) HK1012265A1 (pt)
MX (1) MX9200754A (pt)
PT (1) PT100156B (pt)
WO (1) WO1992014469A1 (pt)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101255406B (zh) * 2005-04-22 2010-05-26 李红霞 人卵巢癌耐药细胞株
ES2371171B1 (es) * 2010-06-08 2012-11-16 Consejo Superior De Investigaciones Científicas (Csic) Derivados de camptotecina como agentes antitumorales.
CN102477042A (zh) * 2010-11-26 2012-05-30 复旦大学 10-羟基喜树碱衍生物及其制备方法和用途

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5004758A (en) * 1987-12-01 1991-04-02 Smithkline Beecham Corporation Water soluble camptothecin analogs useful for inhibiting the growth of animal tumor cells

Also Published As

Publication number Publication date
ATE444755T1 (de) 2009-10-15
JPH06505740A (ja) 1994-06-30
CA2103708C (en) 2004-04-27
ES2349037T3 (es) 2010-12-22
DK1707568T3 (da) 2010-11-08
HK1012265A1 (en) 1999-07-30
EP1690542A2 (en) 2006-08-16
DE69233773D1 (de) 2009-11-19
KR930702983A (ko) 1993-11-29
AU663312B2 (en) 1995-10-05
DE69233793D1 (de) 2010-09-16
DK0572557T3 (da) 2010-02-01
EP1707568A2 (en) 2006-10-04
EP0572557A1 (en) 1993-12-08
EP1707568A3 (en) 2008-03-26
MX9200754A (es) 1992-08-01
CA2103708A1 (en) 1992-08-22
JP2778632B2 (ja) 1998-07-23
ATE476182T1 (de) 2010-08-15
EP1690542A3 (en) 2008-03-26
ES2334178T3 (es) 2010-03-05
AU1461692A (en) 1992-09-15
EP0572557A4 (en) 1993-12-29
PT100156B (pt) 1999-09-30
EP1707568B1 (en) 2010-08-04
WO1992014469A1 (en) 1992-09-03
EP0572557B1 (en) 2009-10-07

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Legal Events

Date Code Title Description
BB1A Laying open of patent application

Effective date: 19930122

FG3A Patent granted, date of granting

Effective date: 19990622

MM4A Annulment/lapse due to non-payment of fees, searched and examined patent

Free format text: MAXIMUM VALIDITY LIMIT REACHED

Effective date: 20140623