ATE476182T1 - Pharmazeutische zusammensetzung zur verwendung in der behandlung von eierstockkrebs - Google Patents

Pharmazeutische zusammensetzung zur verwendung in der behandlung von eierstockkrebs

Info

Publication number
ATE476182T1
ATE476182T1 AT05076845T AT05076845T ATE476182T1 AT E476182 T1 ATE476182 T1 AT E476182T1 AT 05076845 T AT05076845 T AT 05076845T AT 05076845 T AT05076845 T AT 05076845T AT E476182 T1 ATE476182 T1 AT E476182T1
Authority
AT
Austria
Prior art keywords
pharmaceutical composition
topotecan
treatment
ovarian cancer
human
Prior art date
Application number
AT05076845T
Other languages
English (en)
Inventor
Randall Johnson
Original Assignee
Glaxosmithkline Llc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Glaxosmithkline Llc filed Critical Glaxosmithkline Llc
Application granted granted Critical
Publication of ATE476182T1 publication Critical patent/ATE476182T1/de

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/535Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one oxygen as the ring hetero atoms, e.g. 1,2-oxazines
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D491/00Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
    • C07D491/12Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains three hetero rings
    • C07D491/16Peri-condensed systems
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44Non condensed pyridines; Hydrogenated derivatives thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47Quinolines; Isoquinolines
    • A61K31/4738Quinolines; Isoquinolines ortho- or peri-condensed with heterocyclic ring systems
    • A61K31/4741Quinolines; Isoquinolines ortho- or peri-condensed with heterocyclic ring systems condensed with ring systems having oxygen as a ring hetero atom, e.g. tubocuraran derivatives, noscapine, bicuculline
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47Quinolines; Isoquinolines
    • A61K31/4738Quinolines; Isoquinolines ortho- or peri-condensed with heterocyclic ring systems
    • A61K31/4745Quinolines; Isoquinolines ortho- or peri-condensed with heterocyclic ring systems condensed with ring systems having nitrogen as a ring hetero atom, e.g. phenantrolines
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D491/00Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
    • C07D491/22Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains four or more hetero rings
AT05076845T 1991-02-21 1992-02-07 Pharmazeutische zusammensetzung zur verwendung in der behandlung von eierstockkrebs ATE476182T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US65894891A 1991-02-21 1991-02-21

Publications (1)

Publication Number Publication Date
ATE476182T1 true ATE476182T1 (de) 2010-08-15

Family

ID=24643386

Family Applications (2)

Application Number Title Priority Date Filing Date
AT92907833T ATE444755T1 (de) 1991-02-21 1992-02-07 Verwendung von topotecan zur herstellung eines medikaments zur verwendung in der behandlung von ovarialkrebs
AT05076845T ATE476182T1 (de) 1991-02-21 1992-02-07 Pharmazeutische zusammensetzung zur verwendung in der behandlung von eierstockkrebs

Family Applications Before (1)

Application Number Title Priority Date Filing Date
AT92907833T ATE444755T1 (de) 1991-02-21 1992-02-07 Verwendung von topotecan zur herstellung eines medikaments zur verwendung in der behandlung von ovarialkrebs

Country Status (13)

Country Link
EP (3) EP1690542A3 (de)
JP (1) JP2778632B2 (de)
KR (1) KR930702983A (de)
AT (2) ATE444755T1 (de)
AU (1) AU663312B2 (de)
CA (1) CA2103708C (de)
DE (2) DE69233793D1 (de)
DK (2) DK0572557T3 (de)
ES (2) ES2334178T3 (de)
HK (1) HK1012265A1 (de)
MX (1) MX9200754A (de)
PT (1) PT100156B (de)
WO (1) WO1992014469A1 (de)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101255406B (zh) * 2005-04-22 2010-05-26 李红霞 人卵巢癌耐药细胞株
ES2371171B1 (es) * 2010-06-08 2012-11-16 Consejo Superior De Investigaciones Científicas (Csic) Derivados de camptotecina como agentes antitumorales.
CN102477042A (zh) * 2010-11-26 2012-05-30 复旦大学 10-羟基喜树碱衍生物及其制备方法和用途

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5004758A (en) 1987-12-01 1991-04-02 Smithkline Beecham Corporation Water soluble camptothecin analogs useful for inhibiting the growth of animal tumor cells

Also Published As

Publication number Publication date
DE69233773D1 (de) 2009-11-19
EP1707568B1 (de) 2010-08-04
JP2778632B2 (ja) 1998-07-23
EP1707568A3 (de) 2008-03-26
ES2349037T3 (es) 2010-12-22
PT100156B (pt) 1999-09-30
AU1461692A (en) 1992-09-15
EP0572557A4 (en) 1993-12-29
MX9200754A (es) 1992-08-01
EP1690542A3 (de) 2008-03-26
DK0572557T3 (da) 2010-02-01
CA2103708A1 (en) 1992-08-22
AU663312B2 (en) 1995-10-05
ATE444755T1 (de) 2009-10-15
EP0572557B1 (de) 2009-10-07
DE69233793D1 (de) 2010-09-16
CA2103708C (en) 2004-04-27
JPH06505740A (ja) 1994-06-30
EP1690542A2 (de) 2006-08-16
KR930702983A (ko) 1993-11-29
PT100156A (pt) 1993-05-31
HK1012265A1 (en) 1999-07-30
WO1992014469A1 (en) 1992-09-03
EP0572557A1 (de) 1993-12-08
DK1707568T3 (da) 2010-11-08
ES2334178T3 (es) 2010-03-05
EP1707568A2 (de) 2006-10-04

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