DK170343B1 - Fremgangsmåde til fremstilling af forbindelser beslægtet med avermectiner - Google Patents

Fremgangsmåde til fremstilling af forbindelser beslægtet med avermectiner Download PDF

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Publication number
DK170343B1
DK170343B1 DK627088A DK627088A DK170343B1 DK 170343 B1 DK170343 B1 DK 170343B1 DK 627088 A DK627088 A DK 627088A DK 627088 A DK627088 A DK 627088A DK 170343 B1 DK170343 B1 DK 170343B1
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Prior art keywords
formula
absent
alkyl
compounds
optional bond
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Application number
DK627088A
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Danish (da)
English (en)
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DK627088A (da
DK627088D0 (da
Inventor
Christopher James Dutton
Stephen Paul Gibson
Shin-Jen Edward Lee
Original Assignee
Pfizer Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
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Publication date
Application filed by Pfizer Ltd filed Critical Pfizer Ltd
Publication of DK627088D0 publication Critical patent/DK627088D0/da
Publication of DK627088A publication Critical patent/DK627088A/da
Application granted granted Critical
Publication of DK170343B1 publication Critical patent/DK170343B1/da

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
    • C07H19/01—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing oxygen
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00—Antiparasitic agents
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S435/00—Chemistry: molecular biology and microbiology
    • Y10S435/8215—Microorganisms
    • Y10S435/822—Microorganisms using bacteria or actinomycetales
    • Y10S435/886—Streptomyces

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  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Molecular Biology (AREA)
  • Veterinary Medicine (AREA)
  • Genetics & Genomics (AREA)
  • Biotechnology (AREA)
  • Biochemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Saccharide Compounds (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
DK627088A 1987-11-14 1988-11-10 Fremgangsmåde til fremstilling af forbindelser beslægtet med avermectiner DK170343B1 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB878726730A GB8726730D0 (en) 1987-11-14 1987-11-14 Antiparasitic agents
GB8726730 1987-11-14

Publications (3)

Publication Number Publication Date
DK627088D0 DK627088D0 (da) 1988-11-10
DK627088A DK627088A (da) 1989-06-22
DK170343B1 true DK170343B1 (da) 1995-08-07

Family

ID=10626990

Family Applications (1)

Application Number Title Priority Date Filing Date
DK627088A DK170343B1 (da) 1987-11-14 1988-11-10 Fremgangsmåde til fremstilling af forbindelser beslægtet med avermectiner

Country Status (10)

Country Link
US (2) US5702924A (de)
EP (1) EP0317148B1 (de)
JP (1) JP2854869B2 (de)
AT (1) ATE85796T1 (de)
DE (1) DE3878535T2 (de)
DK (1) DK170343B1 (de)
ES (1) ES2053764T3 (de)
GB (1) GB8726730D0 (de)
IE (1) IE61513B1 (de)
PT (1) PT88991B (de)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB8813760D0 (en) * 1988-06-10 1988-07-13 American Cyanamid Co Chemical process
GB8815967D0 (en) * 1988-07-05 1988-08-10 Pfizer Ltd Antiparasitic agents
US5055454A (en) * 1989-10-30 1991-10-08 Merck & Co., Inc. 13-epi-avermectin derivatives useful as antiparasitic agents
US5192671A (en) * 1991-06-26 1993-03-09 Merck & Co., Inc. Process for the glycosylation of avermectin compounds
GB9205007D0 (en) * 1992-03-07 1992-04-22 Pfizer Ltd Antiparasitic agents
US6103504A (en) * 1992-03-25 2000-08-15 Pfizer Inc. Process for production of avermectins and cultures therefor
GB9316129D0 (en) * 1993-08-04 1993-09-22 Pfizer Ltd Antiprasatic agents
DE4427766A1 (de) * 1994-08-05 1996-02-08 Basf Ag Verfahren zur Herstellung flüssigkristalliner Mischungen
AP1060A (en) 1998-01-02 2002-04-23 Pfizer Prod Inc Novel erythromycin derivatives.
GB9825402D0 (en) 1998-11-19 1999-01-13 Pfizer Ltd Antiparasitic formulations
DK1435786T3 (da) 2001-09-17 2011-10-03 Lilly Co Eli Pesticide formuleringer
MX2012004523A (es) 2009-10-19 2012-05-08 Intervet Int Bv Metodo y formulacion para el control de parasitos.

Family Cites Families (26)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SE434277B (sv) * 1976-04-19 1984-07-16 Merck & Co Inc Sett att framstella nya antihelmintiskt verkande foreningar genom odling av streptomyces avermitilis
US4134973A (en) * 1977-04-11 1979-01-16 Merck & Co., Inc. Carbohydrate derivatives of milbemycin and processes therefor
NZ186851A (en) * 1977-04-11 1984-12-14 Merck & Co Inc Glycosyloxy derivatives of milbemycin and parasiticidal compositions
US4199569A (en) * 1977-10-03 1980-04-22 Merck & Co., Inc. Selective hydrogenation products of C-076 compounds and derivatives thereof
PH15982A (en) * 1977-10-03 1983-05-18 Merck & Co Inc Selective hydrogenation producta of c-076 compounds and derivatives thereof
PH16612A (en) * 1977-12-19 1983-11-28 Merck & Co Inc 13-halo and 13-deoxy derivatives of c-076 compounds
US4200581A (en) * 1978-08-04 1980-04-29 Merck & Co., Inc. Alkyl derivatives of C-076 compounds
US4429042A (en) * 1978-09-08 1984-01-31 Merck & Co., Inc. Strain of Streptomyces for producing antiparasitic compounds
US4328335A (en) * 1979-08-13 1982-05-04 Merck & Co., Inc. Process for the interconversion of C-076 compounds
US4285963A (en) * 1980-08-07 1981-08-25 Merck & Co., Inc. Novel derivatives of C-076 compounds
US4378353A (en) * 1981-02-17 1983-03-29 Merck & Co., Inc. Novel C-076 compounds
US4333925A (en) * 1981-05-11 1982-06-08 Merck & Co., Inc. Derivatives of C-076 compounds
US4423209A (en) * 1982-02-26 1983-12-27 Merck & Co., Inc. Processes for the interconversion of avermectin compounds
DE3532794A1 (de) * 1984-09-14 1986-04-17 Glaxo Group Ltd., London Antibiotika, verfahren zu deren herstellung und diese verbindungen enthaltende mittel
HUT39739A (en) * 1984-12-04 1986-10-29 Ciba Geigy Ag Process for production of derivatives of 13,3-milbemycin and medical preparatives containing thereof
GB8502925D0 (en) * 1985-02-05 1985-03-06 Ici Plc Macrocyclic lactones
ES8802229A1 (es) * 1985-04-30 1988-04-16 Glaxo Group Ltd Un procedimiento para preparar nuevos derivados lactonicos macrociclicos.
ES8800986A1 (es) * 1985-07-27 1987-12-01 Pfizer Un procedimiento para la produccion de un nuevo derivado de avermectina
ATE119905T1 (de) * 1985-09-13 1995-04-15 American Cyanamid Co Makrolide antibiotika und verfahren zu deren herstellung.
EP0235085A1 (de) * 1986-02-20 1987-09-02 Ciba-Geigy Ag 13-Beta-Zuckerderivate von Milbemycinen, deren Herstellung und Verwendung gegen Ekto-und Endoparasiten am Nutztier oder an der Nutzpflanze
GB8606120D0 (en) * 1986-03-12 1986-04-16 Glaxo Group Ltd Process
US4831016A (en) * 1986-10-31 1989-05-16 Merck & Co., Inc. Reduced avermectin derivatives
JPH0725765B2 (ja) * 1987-03-17 1995-03-22 三共株式会社 抗生物質ミルベマイシン化合物およびその製造法
DE3888936T2 (de) * 1987-11-03 1994-07-21 Beecham Group Plc Zwischenprodukte für die Herstellung makrolider Antibiotika mit anthelmintischer Wirkung.
DE3880088T2 (de) * 1987-11-09 1993-07-22 Pfizer Ethylierte avermectine.
US5244879A (en) * 1992-03-18 1993-09-14 Merck & Co., Inc. 23-nor-23-oxa avermectin analogs are active anthelmintic agents

Also Published As

Publication number Publication date
DE3878535D1 (de) 1993-03-25
DK627088A (da) 1989-06-22
DK627088D0 (da) 1988-11-10
IE883399L (en) 1989-05-14
ATE85796T1 (de) 1993-03-15
EP0317148A2 (de) 1989-05-24
GB8726730D0 (en) 1987-12-16
JP2854869B2 (ja) 1999-02-10
PT88991B (pt) 1993-02-26
US6362168B1 (en) 2002-03-26
DE3878535T2 (de) 1993-06-03
US5702924A (en) 1997-12-30
EP0317148B1 (de) 1993-02-17
EP0317148A3 (en) 1990-11-28
JPH01160983A (ja) 1989-06-23
IE61513B1 (en) 1994-11-16
ES2053764T3 (es) 1994-08-01
PT88991A (pt) 1988-12-01

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B1 Patent granted (law 1993)
PBP Patent lapsed

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