DK170224B1 - Adjuveret antigenopløsning, dens fremstilling samt zink- eller jernhydroxidgel til anvendelse derved - Google Patents

Adjuveret antigenopløsning, dens fremstilling samt zink- eller jernhydroxidgel til anvendelse derved Download PDF

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Publication number
DK170224B1
DK170224B1 DK504389A DK504389A DK170224B1 DK 170224 B1 DK170224 B1 DK 170224B1 DK 504389 A DK504389 A DK 504389A DK 504389 A DK504389 A DK 504389A DK 170224 B1 DK170224 B1 DK 170224B1
Authority
DK
Denmark
Prior art keywords
zinc
hydroxide gel
iron hydroxide
lecithin
vaccine
Prior art date
Application number
DK504389A
Other languages
Danish (da)
English (en)
Other versions
DK504389D0 (da
DK504389A (da
Inventor
Dieter Bernhardt
Original Assignee
Behringwerke Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Behringwerke Ag filed Critical Behringwerke Ag
Publication of DK504389D0 publication Critical patent/DK504389D0/da
Publication of DK504389A publication Critical patent/DK504389A/da
Application granted granted Critical
Publication of DK170224B1 publication Critical patent/DK170224B1/da

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/39—Medicinal preparations containing antigens or antibodies characterised by the immunostimulating additives, e.g. chemical adjuvants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K33/00—Medicinal preparations containing inorganic active ingredients
    • A61K33/24—Heavy metals; Compounds thereof
    • A61K33/26—Iron; Compounds thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K33/00—Medicinal preparations containing inorganic active ingredients
    • A61K33/24—Heavy metals; Compounds thereof
    • A61K33/30—Zinc; Compounds thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/04—Immunostimulants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
    • A61K2039/55505—Inorganic adjuvants

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Epidemiology (AREA)
  • Immunology (AREA)
  • Inorganic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Microbiology (AREA)
  • Mycology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Organic Chemistry (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Other Investigation Or Analysis Of Materials By Electrical Means (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
DK504389A 1988-10-12 1989-10-11 Adjuveret antigenopløsning, dens fremstilling samt zink- eller jernhydroxidgel til anvendelse derved DK170224B1 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE3834729A DE3834729A1 (de) 1988-10-12 1988-10-12 Verwendung von zink-oder eisenhydroxid zur adjuvierung von antigenloesungen und auf diese weise adjuvierte antigenloesungen
DE3834729 1988-10-12

Publications (3)

Publication Number Publication Date
DK504389D0 DK504389D0 (da) 1989-10-11
DK504389A DK504389A (da) 1990-04-13
DK170224B1 true DK170224B1 (da) 1995-07-03

Family

ID=6364944

Family Applications (1)

Application Number Title Priority Date Filing Date
DK504389A DK170224B1 (da) 1988-10-12 1989-10-11 Adjuveret antigenopløsning, dens fremstilling samt zink- eller jernhydroxidgel til anvendelse derved

Country Status (13)

Country Link
US (1) US5252327A (ko)
EP (1) EP0363835B1 (ko)
JP (1) JP2756321B2 (ko)
KR (1) KR0162074B1 (ko)
AT (1) ATE90568T1 (ko)
AU (1) AU626920B2 (ko)
CA (1) CA1333257C (ko)
DE (2) DE3834729A1 (ko)
DK (1) DK170224B1 (ko)
ES (1) ES2058432T3 (ko)
FI (1) FI100946B (ko)
IE (1) IE63271B1 (ko)
PT (1) PT91953B (ko)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE4007315A1 (de) * 1990-03-08 1991-09-12 Behringwerke Ag Verwendung von zink-calciumhydroxid, lecithin und pao zur adjuvierung von antigenloesungen und auf diese weise adjuvierte antigenloesungen
EP0640348A1 (en) * 1993-07-26 1995-03-01 Akzo Nobel N.V. Oil-based and water-based adjuvant mixture
DE4333376C2 (de) * 1993-09-30 1995-09-07 Gerbu Biotechnik Gmbh Mittel zur Steigerung der Ausbeute von Antikörpern in der Immunologie
DE19511276C2 (de) * 1995-03-27 1999-02-18 Immuno Ag Adjuvans auf der Basis kolloidaler Eisenverbindungen
DE69935606T9 (de) * 1998-10-16 2021-03-11 Glaxosmithkline Biologicals S.A. Adjuvanzsysteme und impfstoffe
AT408721B (de) * 1999-10-01 2002-02-25 Cistem Biotechnologies Gmbh Pharmazeutische zusammensetzung enthaltend ein antigen
DE20103715U1 (de) * 2001-03-05 2002-07-25 Nawa Heilmittel Gmbh Medizinisches Präparat zur Förderung des Anwachsens eines Transplantats, insbesondere von transplantierter Haut an einem Transplantationsort
US20040131643A1 (en) * 2001-03-05 2004-07-08 Harleen Grewal Immune response potentiation
FR2854803B1 (fr) * 2003-05-16 2005-06-24 Aventis Pasteur Composition vaccinale comprenant du phosphate de fer a titre d'adjuvent vaccinal.
DE602004030343D1 (de) * 2003-07-11 2011-01-13 Intercell Ag Hcv-vakzin
WO2007025332A1 (en) * 2005-08-29 2007-03-08 Dia-B Tech Limited A peptide and zinc ion composition for treating diabetes and enhancing immune function
JP5798356B2 (ja) * 2011-04-06 2015-10-21 一般財団法人化学及血清療法研究所 新規インフルエンザワクチン安定化剤
GB2571925A (en) * 2018-03-08 2019-09-18 Univ Antwerpen Iron-based vaccine adjuvants
EP3954386A4 (en) 2019-04-11 2022-07-06 Xiamen Innovax Biotech Co., Ltd. PREPARATION OF A ZINC ZOLEDRONATE MICRO-NANOPARTICLE ADJUVANT AND ITS USE AS A VACCINE ADJUVANT

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1189340A (en) * 1967-09-13 1970-04-22 American Cyanamid Co Antigen-Adjuvant Composition
US4684625A (en) * 1982-07-08 1987-08-04 Syntex (U.S.A.) Inc. Method for enhancing the anti-infective activity of muramyldipeptide derivatives
DE3241113A1 (de) * 1982-11-06 1984-05-10 Bayer Ag, 5090 Leverkusen Vakzinen mit zuschlagstoffen
US4981684A (en) * 1989-10-24 1991-01-01 Coopers Animal Health Limited Formation of adjuvant complexes

Also Published As

Publication number Publication date
DK504389D0 (da) 1989-10-11
EP0363835A1 (de) 1990-04-18
DE3834729A1 (de) 1990-04-19
FI894804A (fi) 1990-04-13
FI894804A0 (fi) 1989-10-10
PT91953B (pt) 1995-05-31
IE893283L (en) 1990-04-12
US5252327A (en) 1993-10-12
KR0162074B1 (ko) 1998-12-01
ES2058432T3 (es) 1994-11-01
ATE90568T1 (de) 1993-07-15
AU4276689A (en) 1990-04-26
CA1333257C (en) 1994-11-29
FI100946B (fi) 1998-03-31
EP0363835B1 (de) 1993-06-16
AU626920B2 (en) 1992-08-13
JPH02149530A (ja) 1990-06-08
KR900005986A (ko) 1990-05-07
DK504389A (da) 1990-04-13
JP2756321B2 (ja) 1998-05-25
DE58904713D1 (de) 1993-07-22
PT91953A (pt) 1990-04-30
IE63271B1 (en) 1995-04-05

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B1 Patent granted (law 1993)
PBP Patent lapsed

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