ES2058432T3 - Utilizacion de hidroxido de zinc o de hierro para la coadyuvacion de soluciones de antigenos, y soluciones de antigenos coadyuvadas de este modo. - Google Patents

Utilizacion de hidroxido de zinc o de hierro para la coadyuvacion de soluciones de antigenos, y soluciones de antigenos coadyuvadas de este modo.

Info

Publication number
ES2058432T3
ES2058432T3 ES89118565T ES89118565T ES2058432T3 ES 2058432 T3 ES2058432 T3 ES 2058432T3 ES 89118565 T ES89118565 T ES 89118565T ES 89118565 T ES89118565 T ES 89118565T ES 2058432 T3 ES2058432 T3 ES 2058432T3
Authority
ES
Spain
Prior art keywords
antigen solutions
zinc
coadjuved
adjustment
way
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES89118565T
Other languages
English (en)
Inventor
Dieter Dr Bernhardt
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Siemens Healthcare Diagnostics GmbH Germany
Original Assignee
Behringwerke AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Behringwerke AG filed Critical Behringwerke AG
Application granted granted Critical
Publication of ES2058432T3 publication Critical patent/ES2058432T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/39—Medicinal preparations containing antigens or antibodies characterised by the immunostimulating additives, e.g. chemical adjuvants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K33/00—Medicinal preparations containing inorganic active ingredients
    • A61K33/24—Heavy metals; Compounds thereof
    • A61K33/26—Iron; Compounds thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K33/00—Medicinal preparations containing inorganic active ingredients
    • A61K33/24—Heavy metals; Compounds thereof
    • A61K33/30—Zinc; Compounds thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/04—Immunostimulants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
    • A61K2039/55505—Inorganic adjuvants

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Epidemiology (AREA)
  • Immunology (AREA)
  • Inorganic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Microbiology (AREA)
  • Mycology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Organic Chemistry (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Other Investigation Or Analysis Of Materials By Electrical Means (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

Abstract

EL INVENTO DESCRIBE LA APLICACION DE GELES HIDROXIDO DE CINC EÑO HIDROXIDO DE HIERRO Y LECITINAS PARA AJUSTAR LAS SOLUCIONES DE ANTIGENOS.
ES89118565T 1988-10-12 1989-10-06 Utilizacion de hidroxido de zinc o de hierro para la coadyuvacion de soluciones de antigenos, y soluciones de antigenos coadyuvadas de este modo. Expired - Lifetime ES2058432T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE3834729A DE3834729A1 (de) 1988-10-12 1988-10-12 Verwendung von zink-oder eisenhydroxid zur adjuvierung von antigenloesungen und auf diese weise adjuvierte antigenloesungen

Publications (1)

Publication Number Publication Date
ES2058432T3 true ES2058432T3 (es) 1994-11-01

Family

ID=6364944

Family Applications (1)

Application Number Title Priority Date Filing Date
ES89118565T Expired - Lifetime ES2058432T3 (es) 1988-10-12 1989-10-06 Utilizacion de hidroxido de zinc o de hierro para la coadyuvacion de soluciones de antigenos, y soluciones de antigenos coadyuvadas de este modo.

Country Status (13)

Country Link
US (1) US5252327A (es)
EP (1) EP0363835B1 (es)
JP (1) JP2756321B2 (es)
KR (1) KR0162074B1 (es)
AT (1) ATE90568T1 (es)
AU (1) AU626920B2 (es)
CA (1) CA1333257C (es)
DE (2) DE3834729A1 (es)
DK (1) DK170224B1 (es)
ES (1) ES2058432T3 (es)
FI (1) FI100946B (es)
IE (1) IE63271B1 (es)
PT (1) PT91953B (es)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE4007315A1 (de) * 1990-03-08 1991-09-12 Behringwerke Ag Verwendung von zink-calciumhydroxid, lecithin und pao zur adjuvierung von antigenloesungen und auf diese weise adjuvierte antigenloesungen
EP0640348A1 (en) * 1993-07-26 1995-03-01 Akzo Nobel N.V. Oil-based and water-based adjuvant mixture
DE4333376C2 (de) * 1993-09-30 1995-09-07 Gerbu Biotechnik Gmbh Mittel zur Steigerung der Ausbeute von Antikörpern in der Immunologie
DE19511276C2 (de) * 1995-03-27 1999-02-18 Immuno Ag Adjuvans auf der Basis kolloidaler Eisenverbindungen
CA2347099C (en) * 1998-10-16 2014-08-05 Smithkline Beecham Biologicals S.A. Adjuvant systems comprising an immunostimulant adsorbed to a metallic salt particle and vaccines thereof
AT408721B (de) * 1999-10-01 2002-02-25 Cistem Biotechnologies Gmbh Pharmazeutische zusammensetzung enthaltend ein antigen
DE20103715U1 (de) * 2001-03-05 2002-07-25 Nawa-Heilmittel GmbH, 92361 Berngau Medizinisches Präparat zur Förderung des Anwachsens eines Transplantats, insbesondere von transplantierter Haut an einem Transplantationsort
AP2003002867A0 (en) * 2001-03-05 2003-09-30 Forinnova As Immune response potentiation
FR2854803B1 (fr) * 2003-05-16 2005-06-24 Aventis Pasteur Composition vaccinale comprenant du phosphate de fer a titre d'adjuvent vaccinal.
TWI358301B (en) * 2003-07-11 2012-02-21 Intercell Ag Hcv vaccines
WO2007025332A1 (en) * 2005-08-29 2007-03-08 Dia-B Tech Limited A peptide and zinc ion composition for treating diabetes and enhancing immune function
JP5798356B2 (ja) * 2011-04-06 2015-10-21 一般財団法人化学及血清療法研究所 新規インフルエンザワクチン安定化剤
GB2571925A (en) * 2018-03-08 2019-09-18 Univ Antwerpen Iron-based vaccine adjuvants
US20220193231A1 (en) * 2019-04-11 2022-06-23 Xiamen Innovax Biotech Co., Ltd. Preparation of zinc zoledronate micro-nanoparticle adjuvant and use thereof as vaccine adjuvant

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1189340A (en) * 1967-09-13 1970-04-22 American Cyanamid Co Antigen-Adjuvant Composition
US4684625A (en) * 1982-07-08 1987-08-04 Syntex (U.S.A.) Inc. Method for enhancing the anti-infective activity of muramyldipeptide derivatives
DE3241113A1 (de) * 1982-11-06 1984-05-10 Bayer Ag, 5090 Leverkusen Vakzinen mit zuschlagstoffen
US4981684A (en) * 1989-10-24 1991-01-01 Coopers Animal Health Limited Formation of adjuvant complexes

Also Published As

Publication number Publication date
EP0363835B1 (de) 1993-06-16
AU626920B2 (en) 1992-08-13
IE893283L (en) 1990-04-12
DE58904713D1 (de) 1993-07-22
ATE90568T1 (de) 1993-07-15
FI100946B (fi) 1998-03-31
FI894804A0 (fi) 1989-10-10
IE63271B1 (en) 1995-04-05
US5252327A (en) 1993-10-12
PT91953A (pt) 1990-04-30
JP2756321B2 (ja) 1998-05-25
KR0162074B1 (ko) 1998-12-01
JPH02149530A (ja) 1990-06-08
FI894804A (fi) 1990-04-13
KR900005986A (ko) 1990-05-07
AU4276689A (en) 1990-04-26
DK170224B1 (da) 1995-07-03
DK504389D0 (da) 1989-10-11
CA1333257C (en) 1994-11-29
DK504389A (da) 1990-04-13
DE3834729A1 (de) 1990-04-19
EP0363835A1 (de) 1990-04-18
PT91953B (pt) 1995-05-31

Similar Documents

Publication Publication Date Title
BR8901053A (pt) Regulador de pressao,e combinacao de valvula/regulador
ES2058432T3 (es) Utilizacion de hidroxido de zinc o de hierro para la coadyuvacion de soluciones de antigenos, y soluciones de antigenos coadyuvadas de este modo.
BR9102656A (pt) Valvula reguladora de pressao
DE58901096D1 (de) Ventillamelle.
CA2071981A1 (en) The use of gaba-b selective agonists as anti-tussive agents
DE59001941D1 (de) Magnetventilbatterie.
DE69001463D1 (de) Mikroleckregulierventil.
ES2093458T3 (es) Procedimiento para la obtencion de 1,1,1,3,3-pentafluorpropano.
GB2216990B (en) An override check valve
DE3763501D1 (de) Stosswellenquelle mit piezokeramischer druckquelle.
EP0329961A3 (en) Use of 2-oxo-pyrrolidine-1-acetamide for the determination of glomerular filtration rate in humans
DE69116321D1 (de) Immunostimulierendes Mittel das Interleukin-2 und 5'-Deoxy-5-fluorouridin enthält
CA2037709A1 (en) Use of zinc calcium hydroxide, lecithin and pao as an adjuvant for antigen solutions, and antigen solutions treated with an adjuvant of this type
EP0350738A3 (de) (S)-Emopamil zur Anwendung bei der Behandlung von Migräne
ZA849576B (en) 1,7-diphenyl-3-methyllaza-7-cyano-8-methylnonane for use in the treatment of diseases
DK162948C (da) Trykmiddelaktiveret indstillingsmotor
HK88396A (en) 24r-scymnol and preparation and use thereof
NO178085C (no) Hovedventil
GR3029726T3 (en) Use of a therapeutic compound for the treatment of bronchitis
BR8900188A (pt) Jogo de valvulas para compressores de embolo
UA15635A (uk) Пристрій для остеосиhтезу
ES1007058Y (es) Lampara orientable.
SU1644473A1 (ru) Соли n,n'-бис-(2-карбоксиэтил)-4,4'-дипиридилия, обладающие дефолиирующим и высушивающим действием
SE9001867D0 (sv) Solariemadrass
BR6801404U (pt) Aparelho para bronzeamento artificial

Legal Events

Date Code Title Description
FG2A Definitive protection

Ref document number: 363835

Country of ref document: ES