DK170201B1 - 5-Alkylsulfonamido-2-(N-alkylsulfonamidoheterocyclylmethyl-N-methyl-amino)indan-forbindelser, disse forbindelser til anvendelse som lægemidler, anvendelse af forbindelserne til fremstilling af antiarytmi-lægemidler og farmaceutiske præparater indeholdende forbindelserne, samt 2-(N-methylamino)indan-forbindelser, der er nyttige som mellemprodukter - Google Patents

5-Alkylsulfonamido-2-(N-alkylsulfonamidoheterocyclylmethyl-N-methyl-amino)indan-forbindelser, disse forbindelser til anvendelse som lægemidler, anvendelse af forbindelserne til fremstilling af antiarytmi-lægemidler og farmaceutiske præparater indeholdende forbindelserne, samt 2-(N-methylamino)indan-forbindelser, der er nyttige som mellemprodukter Download PDF

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Publication number
DK170201B1
DK170201B1 DK160688A DK160688A DK170201B1 DK 170201 B1 DK170201 B1 DK 170201B1 DK 160688 A DK160688 A DK 160688A DK 160688 A DK160688 A DK 160688A DK 170201 B1 DK170201 B1 DK 170201B1
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DK
Denmark
Prior art keywords
compounds
methylamino
formula
evaporated
preparation
Prior art date
Application number
DK160688A
Other languages
Danish (da)
English (en)
Other versions
DK160688A (da
DK160688D0 (da
Inventor
Peter Edward Cross
John Edmund Arrowsmith
Original Assignee
Pfizer Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer Ltd filed Critical Pfizer Ltd
Publication of DK160688D0 publication Critical patent/DK160688D0/da
Publication of DK160688A publication Critical patent/DK160688A/da
Application granted granted Critical
Publication of DK170201B1 publication Critical patent/DK170201B1/da

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
    • C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
    • C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D215/38—Nitrogen atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/06—Antiarrhythmics
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
    • C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
    • C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D215/18—Halogen atoms or nitro radicals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/77—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D307/78—Benzo [b] furans; Hydrogenated benzo [b] furans
    • C07D307/79—Benzo [b] furans; Hydrogenated benzo [b] furans with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to carbon atoms of the hetero ring
    • C07D307/81—Radicals substituted by nitrogen atoms not forming part of a nitro radical

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Cardiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Quinoline Compounds (AREA)
  • Furan Compounds (AREA)
  • Saccharide Compounds (AREA)
DK160688A 1987-03-25 1988-03-24 5-Alkylsulfonamido-2-(N-alkylsulfonamidoheterocyclylmethyl-N-methyl-amino)indan-forbindelser, disse forbindelser til anvendelse som lægemidler, anvendelse af forbindelserne til fremstilling af antiarytmi-lægemidler og farmaceutiske præparater indeholdende forbindelserne, samt 2-(N-methylamino)indan-forbindelser, der er nyttige som mellemprodukter DK170201B1 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB8707122 1987-03-25
GB878707122A GB8707122D0 (en) 1987-03-25 1987-03-25 Antiarrhythmic agents

Publications (3)

Publication Number Publication Date
DK160688D0 DK160688D0 (da) 1988-03-24
DK160688A DK160688A (da) 1989-01-10
DK170201B1 true DK170201B1 (da) 1995-06-12

Family

ID=10614608

Family Applications (1)

Application Number Title Priority Date Filing Date
DK160688A DK170201B1 (da) 1987-03-25 1988-03-24 5-Alkylsulfonamido-2-(N-alkylsulfonamidoheterocyclylmethyl-N-methyl-amino)indan-forbindelser, disse forbindelser til anvendelse som lægemidler, anvendelse af forbindelserne til fremstilling af antiarytmi-lægemidler og farmaceutiske præparater indeholdende forbindelserne, samt 2-(N-methylamino)indan-forbindelser, der er nyttige som mellemprodukter

Country Status (11)

Country Link
US (2) US4829071A (fr)
EP (1) EP0286277B1 (fr)
JP (1) JPS63255266A (fr)
AT (1) ATE53996T1 (fr)
DE (1) DE3860245D1 (fr)
DK (1) DK170201B1 (fr)
ES (1) ES2016408B3 (fr)
GB (1) GB8707122D0 (fr)
GR (1) GR3000581T3 (fr)
IE (1) IE60004B1 (fr)
PT (1) PT87050B (fr)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB8707122D0 (en) * 1987-03-25 1987-04-29 Pfizer Ltd Antiarrhythmic agents
US5006523A (en) * 1989-10-26 1991-04-09 E. R. Squibb & Sons, Inc. Antiarrhythmic agents: aryl cyanoguanidine potassium channel blockers
DK148292D0 (da) * 1992-12-09 1992-12-09 Lundbeck & Co As H Forbindelser
US5382587A (en) * 1993-06-30 1995-01-17 Merck & Co., Inc. Spirocycles
US5403846A (en) * 1993-11-22 1995-04-04 Merck & Co., Inc. Spirocycles
US5439914A (en) * 1994-02-18 1995-08-08 Merck & Co., Inc. Spirocycles
CA2208600A1 (fr) * 1995-02-01 1996-08-08 Pharmacia & Upjohn Company 2-aminoindanes utilises comme ligands selectifs de la dopamine d3
DE19547263C2 (de) * 1995-12-07 1999-04-29 Cardiotec Inc Amidinohydrazone vom Benzo[b]furan abgeleiteter Ketone, Verfahren zu deren Herstellung und diese Verbindungen enthaltende Arzneimittel
US6083991A (en) 1997-06-04 2000-07-04 University Of Florida Research Foundation, Inc. Anti-arrhythmic composition and methods of treatment

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2456911A (en) * 1945-05-04 1948-12-21 Wyeth Corp Disubstituted acetamidyl derivatives of amino quinolines
GB1024650A (en) * 1961-11-03 1966-03-30 Byk Gulden Lomberg Chem Fab Benzofuran derivatives and process for their production
US3513239A (en) * 1967-03-15 1970-05-19 Smithkline Corp Pharmaceutical compositions containing 2-aminoalkyl coumaran derivatives and methods of treating depression therewith
US3923813A (en) * 1969-12-19 1975-12-02 Christiaens Sa A Derivatives of 2-aminoindanes
US4192888A (en) * 1978-04-10 1980-03-11 Smithkline Corporation Pharmaceutical compositions and method of inhibiting phenylethanolamine N-methyltransferase
CA1175851A (fr) * 1980-09-26 1984-10-09 Beecham Group Limited Amines secondaires
US4435422A (en) * 1982-09-15 1984-03-06 Abbott Laboratories 5-Substituted 2,3-dihydrobenzofuran-2-carboxylic acids and their use in diuretic compositions
US4656190A (en) * 1983-11-14 1987-04-07 Merck & Co., Inc. Indene derivatives and their use as PAF-antagonists
EP0164865B1 (fr) * 1984-05-04 1988-12-21 The Upjohn Company N-(aminoalcoylphényl)sulfonamides, leur préparation et leur utilisation thérapeutique
GB8412045D0 (en) * 1984-05-11 1984-06-20 Unilever Plc Detergent compositions
GB8707122D0 (en) * 1987-03-25 1987-04-29 Pfizer Ltd Antiarrhythmic agents

Also Published As

Publication number Publication date
PT87050B (pt) 1992-07-31
IE60004B1 (en) 1994-05-18
ATE53996T1 (de) 1990-07-15
DK160688A (da) 1989-01-10
JPS63255266A (ja) 1988-10-21
EP0286277B1 (fr) 1990-06-20
DK160688D0 (da) 1988-03-24
DE3860245D1 (de) 1990-07-26
GB8707122D0 (en) 1987-04-29
US5130334A (en) 1992-07-14
ES2016408B3 (es) 1990-11-01
US4829071A (en) 1989-05-09
IE880886L (en) 1988-09-25
EP0286277A1 (fr) 1988-10-12
PT87050A (pt) 1988-04-01
JPH0518828B2 (fr) 1993-03-15
GR3000581T3 (en) 1991-07-31

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Legal Events

Date Code Title Description
B1 Patent granted (law 1993)
PBP Patent lapsed
PBP Patent lapsed