DK160688D0 - Ae5-alkylsulfonamido-2-(n-alkylsulfonamidoheterocyclylmethyl-n-methyl-amino)indan-forbindelser, deres anvendelse til fremstilling af antiarrhythmia-laegemidler og farmaceutiske praeparater indeholdende sulfonamiderne samt 2-(n-methylamino)indan-forbindelser, der er nyttige som mellemprodukterae - Google Patents
Ae5-alkylsulfonamido-2-(n-alkylsulfonamidoheterocyclylmethyl-n-methyl-amino)indan-forbindelser, deres anvendelse til fremstilling af antiarrhythmia-laegemidler og farmaceutiske praeparater indeholdende sulfonamiderne samt 2-(n-methylamino)indan-forbindelser, der er nyttige som mellemprodukteraeInfo
- Publication number
- DK160688D0 DK160688D0 DK160688A DK160688A DK160688D0 DK 160688 D0 DK160688 D0 DK 160688D0 DK 160688 A DK160688 A DK 160688A DK 160688 A DK160688 A DK 160688A DK 160688 D0 DK160688 D0 DK 160688D0
- Authority
- DK
- Denmark
- Prior art keywords
- methylamino
- indan
- mellemprodukterae
- alkylsulfonamidoheterocyclylmethyl
- antiarrhythmia
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
- C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
- C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D215/38—Nitrogen atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/06—Antiarrhythmics
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
- C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
- C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D215/18—Halogen atoms or nitro radicals
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
- C07D307/77—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems
- C07D307/78—Benzo [b] furans; Hydrogenated benzo [b] furans
- C07D307/79—Benzo [b] furans; Hydrogenated benzo [b] furans with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to carbon atoms of the hetero ring
- C07D307/81—Radicals substituted by nitrogen atoms not forming part of a nitro radical
Landscapes
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Cardiology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmacology & Pharmacy (AREA)
- Heart & Thoracic Surgery (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Engineering & Computer Science (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Quinoline Compounds (AREA)
- Furan Compounds (AREA)
- Saccharide Compounds (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GB8707122 | 1987-03-25 | ||
GB878707122A GB8707122D0 (en) | 1987-03-25 | 1987-03-25 | Antiarrhythmic agents |
Publications (3)
Publication Number | Publication Date |
---|---|
DK160688D0 true DK160688D0 (da) | 1988-03-24 |
DK160688A DK160688A (da) | 1989-01-10 |
DK170201B1 DK170201B1 (da) | 1995-06-12 |
Family
ID=10614608
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DK160688A DK170201B1 (da) | 1987-03-25 | 1988-03-24 | 5-Alkylsulfonamido-2-(N-alkylsulfonamidoheterocyclylmethyl-N-methyl-amino)indan-forbindelser, disse forbindelser til anvendelse som lægemidler, anvendelse af forbindelserne til fremstilling af antiarytmi-lægemidler og farmaceutiske præparater indeholdende forbindelserne, samt 2-(N-methylamino)indan-forbindelser, der er nyttige som mellemprodukter |
Country Status (11)
Country | Link |
---|---|
US (2) | US4829071A (da) |
EP (1) | EP0286277B1 (da) |
JP (1) | JPS63255266A (da) |
AT (1) | ATE53996T1 (da) |
DE (1) | DE3860245D1 (da) |
DK (1) | DK170201B1 (da) |
ES (1) | ES2016408B3 (da) |
GB (1) | GB8707122D0 (da) |
GR (1) | GR3000581T3 (da) |
IE (1) | IE60004B1 (da) |
PT (1) | PT87050B (da) |
Families Citing this family (9)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB8707122D0 (en) * | 1987-03-25 | 1987-04-29 | Pfizer Ltd | Antiarrhythmic agents |
US5006523A (en) * | 1989-10-26 | 1991-04-09 | E. R. Squibb & Sons, Inc. | Antiarrhythmic agents: aryl cyanoguanidine potassium channel blockers |
DK148292D0 (da) * | 1992-12-09 | 1992-12-09 | Lundbeck & Co As H | Forbindelser |
US5382587A (en) * | 1993-06-30 | 1995-01-17 | Merck & Co., Inc. | Spirocycles |
US5403846A (en) * | 1993-11-22 | 1995-04-04 | Merck & Co., Inc. | Spirocycles |
US5439914A (en) * | 1994-02-18 | 1995-08-08 | Merck & Co., Inc. | Spirocycles |
CN1166622C (zh) * | 1995-02-01 | 2004-09-15 | 法玛西雅厄普约翰美国公司 | 作为选择性多巴胺d3配体的2-氨基-1,2-二氢化茚 |
DE19547263C2 (de) * | 1995-12-07 | 1999-04-29 | Cardiotec Inc | Amidinohydrazone vom Benzo[b]furan abgeleiteter Ketone, Verfahren zu deren Herstellung und diese Verbindungen enthaltende Arzneimittel |
US6083991A (en) | 1997-06-04 | 2000-07-04 | University Of Florida Research Foundation, Inc. | Anti-arrhythmic composition and methods of treatment |
Family Cites Families (11)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US2456911A (en) * | 1945-05-04 | 1948-12-21 | Wyeth Corp | Disubstituted acetamidyl derivatives of amino quinolines |
GB1024650A (en) * | 1961-11-03 | 1966-03-30 | Byk Gulden Lomberg Chem Fab | Benzofuran derivatives and process for their production |
US3513239A (en) * | 1967-03-15 | 1970-05-19 | Smithkline Corp | Pharmaceutical compositions containing 2-aminoalkyl coumaran derivatives and methods of treating depression therewith |
US3923813A (en) * | 1969-12-19 | 1975-12-02 | Christiaens Sa A | Derivatives of 2-aminoindanes |
US4192888A (en) * | 1978-04-10 | 1980-03-11 | Smithkline Corporation | Pharmaceutical compositions and method of inhibiting phenylethanolamine N-methyltransferase |
CA1175851A (en) * | 1980-09-26 | 1984-10-09 | Beecham Group Limited | Secondary amines |
US4435422A (en) * | 1982-09-15 | 1984-03-06 | Abbott Laboratories | 5-Substituted 2,3-dihydrobenzofuran-2-carboxylic acids and their use in diuretic compositions |
US4656190A (en) * | 1983-11-14 | 1987-04-07 | Merck & Co., Inc. | Indene derivatives and their use as PAF-antagonists |
EP0164865B1 (en) * | 1984-05-04 | 1988-12-21 | The Upjohn Company | N-(aminoalkylphenyl)sulfonamides their preparation and therapeutic use |
GB8412045D0 (en) * | 1984-05-11 | 1984-06-20 | Unilever Plc | Detergent compositions |
GB8707122D0 (en) * | 1987-03-25 | 1987-04-29 | Pfizer Ltd | Antiarrhythmic agents |
-
1987
- 1987-03-25 GB GB878707122A patent/GB8707122D0/en active Pending
-
1988
- 1988-02-22 US US07/158,465 patent/US4829071A/en not_active Expired - Fee Related
- 1988-03-23 PT PT87050A patent/PT87050B/pt not_active IP Right Cessation
- 1988-03-24 DE DE8888302599T patent/DE3860245D1/de not_active Expired - Lifetime
- 1988-03-24 DK DK160688A patent/DK170201B1/da not_active IP Right Cessation
- 1988-03-24 EP EP88302599A patent/EP0286277B1/en not_active Expired - Lifetime
- 1988-03-24 IE IE88688A patent/IE60004B1/en not_active IP Right Cessation
- 1988-03-24 AT AT88302599T patent/ATE53996T1/de active
- 1988-03-24 ES ES88302599T patent/ES2016408B3/es not_active Expired - Lifetime
- 1988-03-25 JP JP63071712A patent/JPS63255266A/ja active Granted
-
1989
- 1989-01-30 US US07/303,226 patent/US5130334A/en not_active Expired - Fee Related
-
1990
- 1990-06-21 GR GR90400345T patent/GR3000581T3/el unknown
Also Published As
Publication number | Publication date |
---|---|
IE60004B1 (en) | 1994-05-18 |
PT87050B (pt) | 1992-07-31 |
EP0286277B1 (en) | 1990-06-20 |
DK170201B1 (da) | 1995-06-12 |
ES2016408B3 (es) | 1990-11-01 |
US4829071A (en) | 1989-05-09 |
US5130334A (en) | 1992-07-14 |
JPS63255266A (ja) | 1988-10-21 |
DE3860245D1 (de) | 1990-07-26 |
ATE53996T1 (de) | 1990-07-15 |
EP0286277A1 (en) | 1988-10-12 |
JPH0518828B2 (da) | 1993-03-15 |
IE880886L (en) | 1988-09-25 |
DK160688A (da) | 1989-01-10 |
GR3000581T3 (en) | 1991-07-31 |
GB8707122D0 (en) | 1987-04-29 |
PT87050A (pt) | 1988-04-01 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
B1 | Patent granted (law 1993) | ||
PBP | Patent lapsed | ||
PBP | Patent lapsed |