ES2064341T3 - Nuevas n-(3-hidroxi-4-piperidinil)benzamidas sustituidas. - Google Patents
Nuevas n-(3-hidroxi-4-piperidinil)benzamidas sustituidas.Info
- Publication number
- ES2064341T3 ES2064341T3 ES88201400T ES88201400T ES2064341T3 ES 2064341 T3 ES2064341 T3 ES 2064341T3 ES 88201400 T ES88201400 T ES 88201400T ES 88201400 T ES88201400 T ES 88201400T ES 2064341 T3 ES2064341 T3 ES 2064341T3
- Authority
- ES
- Spain
- Prior art keywords
- 6alkyl
- hydroxy
- hydrogen
- compounds
- piperidinyl
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/445—Non condensed piperidines, e.g. piperocaine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/14—Prodigestives, e.g. acids, enzymes, appetite stimulants, antidyspeptics, tonics, antiflatulents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
- C07D417/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nutrition Science (AREA)
- Epidemiology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Hydrogenated Pyridines (AREA)
- Plural Heterocyclic Compounds (AREA)
- Pyridine Compounds (AREA)
Abstract
NUEVAS BENZAMIDAS N-(3-HIDROXI-4-PIPERIDINIL) SUSTITUIDAS DE FORMULA (I) EN LA QUE LOS SUSTITUYENTES TIENEN EL SIGNIFICADO DADO EN LA INVENCION. ESTOS COMPUESTOS SON AGENTES QUE ESTIMULAN LA MOTILIDAD GASTROINTESTINAL. SE INCLUYEN COMPOSICIONES FARMACEUTICAS QUE CONTIENEN TALES COMPUESTOS COMO INGREDIENTE ACTIVO Y METODOS PARA PREPARAR LOS COMPUESTOS Y LAS COMPOSICIONES.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US7484587A | 1987-07-17 | 1987-07-17 |
Publications (1)
Publication Number | Publication Date |
---|---|
ES2064341T3 true ES2064341T3 (es) | 1995-02-01 |
Family
ID=22122023
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES88201400T Expired - Lifetime ES2064341T3 (es) | 1987-07-17 | 1988-07-05 | Nuevas n-(3-hidroxi-4-piperidinil)benzamidas sustituidas. |
Country Status (23)
Country | Link |
---|---|
EP (1) | EP0299566B1 (es) |
JP (1) | JP2642955B2 (es) |
KR (1) | KR970011156B1 (es) |
CN (1) | CN1020900C (es) |
AT (1) | ATE111098T1 (es) |
AU (1) | AU608338B2 (es) |
BG (1) | BG48809A3 (es) |
CA (1) | CA1317951C (es) |
DE (1) | DE3851388T2 (es) |
DK (1) | DK396088A (es) |
ES (1) | ES2064341T3 (es) |
FI (1) | FI94049C (es) |
HU (1) | HU201926B (es) |
IE (1) | IE64469B1 (es) |
IL (1) | IL87129A (es) |
MA (1) | MA21327A1 (es) |
NO (1) | NO171366C (es) |
NZ (1) | NZ225152A (es) |
PH (1) | PH25531A (es) |
PT (1) | PT87990B (es) |
SU (1) | SU1738088A3 (es) |
TN (1) | TNSN88073A1 (es) |
ZA (1) | ZA885151B (es) |
Families Citing this family (13)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CA1317940C (en) * | 1987-09-25 | 1993-05-18 | Georges H. P. Van Daele | Substituted n-(1-alkyl-3-hydroxy-4-piperidinyl)benzamides |
US5374637A (en) * | 1989-03-22 | 1994-12-20 | Janssen Pharmaceutica N.V. | N-(3-hydroxy-4-piperidinyl)(dihydrobenzofuran, dihydro-2H-benzopyran or dihydrobenzodioxin)carboxamide derivatives |
GB9005014D0 (en) | 1990-03-06 | 1990-05-02 | Janssen Pharmaceutica Nv | N.(4.piperidinyl)(dihydrobenzofuran or dihydro.2h.benzopyran)carboxamide derivatives |
JP2524420B2 (ja) * | 1990-05-16 | 1996-08-14 | 明治製菓株式会社 | ピペリジン誘導体及びそれらを有効成分とする抗潰瘍剤 |
US5082847A (en) * | 1990-07-18 | 1992-01-21 | Syntex (U.S.A.) Inc. | Carbostyril compounds connected via an oxyalkyl group with a piperidine ring and having pharmaceutical utility |
US6096761A (en) * | 1996-02-15 | 2000-08-01 | Janssen Pharmaceutica N.V. | Esters of 3-hydroxy-piperidinemethanol derivatives |
NZ330263A (en) * | 1996-02-15 | 1999-06-29 | Janssen Pharmaceutica Nv | Esters of 3-hydroxy-piperidinemethanol derivatives to improve gastric emptying |
TW548103B (en) * | 1997-07-11 | 2003-08-21 | Janssen Pharmaceutica Nv | Bicyclic benzamides of 3- or 4-substituted 4-(aminomethyl)-piperidine derivatives |
JP3529102B2 (ja) * | 1997-07-11 | 2004-05-24 | ジヤンセン・フアーマシユーチカ・ナームローゼ・フエンノート シヤツプ | 5−ht3および5−ht4介在性障害に有用な(+)−ノルシサプリド |
TW570920B (en) * | 1998-12-22 | 2004-01-11 | Janssen Pharmaceutica Nv | 4-(aminomethyl)-piperidine benzamides for treating gastrointestinal disorders |
WO2005068461A1 (en) * | 2004-01-07 | 2005-07-28 | Aryx Therapeutics | Stereoisomeric compounds and methods for the treatment of gastrointestinal and central nervous system disorders |
KR100976063B1 (ko) * | 2007-03-16 | 2010-08-17 | 동아제약주식회사 | 신규한 벤즈아미드 유도체 화합물 및 그의 제조방법 |
CN110950843B (zh) * | 2019-11-28 | 2022-12-27 | 广东东阳光药业有限公司 | 取代的苯酰胺衍生物及其用途 |
Family Cites Families (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CA1183847A (en) * | 1981-10-01 | 1985-03-12 | Georges Van Daele | N-(3-hydroxy-4-piperidinyl)benzamide derivatives |
US4634704A (en) * | 1983-10-06 | 1987-01-06 | Janssen Pharmaceutica, N.V. | Anti-allergic five membered heterocyclic ring containing N-(bicyclic heterocycyl)-4-piperidinamines |
ZW12187A1 (en) * | 1986-07-03 | 1989-02-01 | Janssen Pharmaceutica Nv | 4-(aroylamino)piperidinebutanamide derivatives |
CA1317940C (en) * | 1987-09-25 | 1993-05-18 | Georges H. P. Van Daele | Substituted n-(1-alkyl-3-hydroxy-4-piperidinyl)benzamides |
-
1988
- 1988-06-23 NZ NZ225152A patent/NZ225152A/en unknown
- 1988-07-01 PH PH37161A patent/PH25531A/en unknown
- 1988-07-05 AT AT88201400T patent/ATE111098T1/de active
- 1988-07-05 ES ES88201400T patent/ES2064341T3/es not_active Expired - Lifetime
- 1988-07-05 DE DE3851388T patent/DE3851388T2/de not_active Expired - Fee Related
- 1988-07-05 EP EP88201400A patent/EP0299566B1/en not_active Expired - Lifetime
- 1988-07-11 SU SU884356073A patent/SU1738088A3/ru active
- 1988-07-14 AU AU19067/88A patent/AU608338B2/en not_active Ceased
- 1988-07-14 CA CA000571979A patent/CA1317951C/en not_active Expired - Fee Related
- 1988-07-14 PT PT87990A patent/PT87990B/pt not_active IP Right Cessation
- 1988-07-15 NO NO883171A patent/NO171366C/no unknown
- 1988-07-15 DK DK396088A patent/DK396088A/da unknown
- 1988-07-15 ZA ZA885151A patent/ZA885151B/xx unknown
- 1988-07-15 BG BG84935A patent/BG48809A3/xx unknown
- 1988-07-15 TN TNTNSN88073A patent/TNSN88073A1/fr unknown
- 1988-07-15 MA MA21570A patent/MA21327A1/fr unknown
- 1988-07-15 FI FI883378A patent/FI94049C/fi not_active IP Right Cessation
- 1988-07-15 IE IE217088A patent/IE64469B1/en not_active IP Right Cessation
- 1988-07-15 JP JP63175269A patent/JP2642955B2/ja not_active Expired - Lifetime
- 1988-07-15 IL IL87129A patent/IL87129A/xx not_active IP Right Cessation
- 1988-07-15 HU HU883707A patent/HU201926B/hu not_active IP Right Cessation
- 1988-07-16 CN CN88104445A patent/CN1020900C/zh not_active Expired - Fee Related
- 1988-07-18 KR KR1019880008929A patent/KR970011156B1/ko not_active IP Right Cessation
Also Published As
Similar Documents
Publication | Publication Date | Title |
---|---|---|
ATE128132T1 (de) | N-(3-hydroxy-4-piperidinyl)(dihydrobenzofuran, dihydro-2h-benzopyran oder dihydrobenzodioxin)- carboxamid-derivate. | |
DE3852085T2 (de) | Substituierte N-(1-Alkyl-3-hydroxy-4-piperidinyl)benzamide. | |
ES2064341T3 (es) | Nuevas n-(3-hidroxi-4-piperidinil)benzamidas sustituidas. |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
FG2A | Definitive protection |
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