DK170069B1 - 1,4-Dihydropyridinforbindelser og farmaceutiske præparater indeholdende disse forbindelser samt forbindelserne til anvendelse ved behandling af cardiovasculære sygdomstilstande - Google Patents
1,4-Dihydropyridinforbindelser og farmaceutiske præparater indeholdende disse forbindelser samt forbindelserne til anvendelse ved behandling af cardiovasculære sygdomstilstande Download PDFInfo
- Publication number
- DK170069B1 DK170069B1 DK355784A DK355784A DK170069B1 DK 170069 B1 DK170069 B1 DK 170069B1 DK 355784 A DK355784 A DK 355784A DK 355784 A DK355784 A DK 355784A DK 170069 B1 DK170069 B1 DK 170069B1
- Authority
- DK
- Denmark
- Prior art keywords
- sub
- compounds
- pyrimidone
- dihydropyridine
- pharmaceutically acceptable
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
- C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D211/80—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members
- C07D211/84—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen directly attached to ring carbon atoms
- C07D211/90—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D473/00—Heterocyclic compounds containing purine ring systems
- C07D473/02—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6
- C07D473/04—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6 two oxygen atoms
- C07D473/06—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6 two oxygen atoms with radicals containing only hydrogen and carbon atoms, attached in position 1 or 3
- C07D473/10—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6 two oxygen atoms with radicals containing only hydrogen and carbon atoms, attached in position 1 or 3 with methyl radicals in positions 3 and 7, e.g. theobromine
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/04—Ortho-condensed systems
Landscapes
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Hydrogenated Pyridines (AREA)
- Plural Heterocyclic Compounds (AREA)
- Polyoxymethylene Polymers And Polymers With Carbon-To-Carbon Bonds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Polyesters Or Polycarbonates (AREA)
- Polymers With Sulfur, Phosphorus Or Metals In The Main Chain (AREA)
- Macromolecular Compounds Obtained By Forming Nitrogen-Containing Linkages In General (AREA)
- Registering, Tensioning, Guiding Webs, And Rollers Therefor (AREA)
- Transition And Organic Metals Composition Catalysts For Addition Polymerization (AREA)
- Crystals, And After-Treatments Of Crystals (AREA)
Applications Claiming Priority (4)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB8319886 | 1983-07-23 | ||
| GB838319886A GB8319886D0 (en) | 1983-07-23 | 1983-07-23 | Therapeutic agents |
| GB848400354A GB8400354D0 (en) | 1984-01-07 | 1984-01-07 | Therapeutic agents |
| GB8400354 | 1984-01-07 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| DK355784D0 DK355784D0 (da) | 1984-07-20 |
| DK355784A DK355784A (da) | 1985-01-24 |
| DK170069B1 true DK170069B1 (da) | 1995-05-15 |
Family
ID=26286678
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK355784A DK170069B1 (da) | 1983-07-23 | 1984-07-20 | 1,4-Dihydropyridinforbindelser og farmaceutiske præparater indeholdende disse forbindelser samt forbindelserne til anvendelse ved behandling af cardiovasculære sygdomstilstande |
Country Status (21)
| Country | Link |
|---|---|
| US (1) | US4568677A (de) |
| EP (1) | EP0132375B1 (de) |
| AT (1) | ATE44146T1 (de) |
| AU (1) | AU547188B2 (de) |
| CA (1) | CA1265796A (de) |
| CS (1) | CS241549B2 (de) |
| DD (1) | DD226285A5 (de) |
| DE (1) | DE3478746D1 (de) |
| DK (1) | DK170069B1 (de) |
| ES (1) | ES8700856A1 (de) |
| FI (1) | FI79105C (de) |
| GR (1) | GR82230B (de) |
| HU (1) | HU212133B (de) |
| IE (1) | IE58443B1 (de) |
| IL (1) | IL72475A (de) |
| NO (1) | NO161174C (de) |
| NZ (1) | NZ208954A (de) |
| PH (1) | PH20479A (de) |
| PL (1) | PL142659B1 (de) |
| PT (1) | PT78958B (de) |
| YU (1) | YU43738B (de) |
Families Citing this family (18)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB8306666D0 (en) * | 1983-03-10 | 1983-04-13 | Pfizer Ltd | Therapeutic agents |
| GR851819B (de) * | 1984-08-17 | 1985-11-26 | Wyeth John & Brother Ltd | |
| GB8501395D0 (en) * | 1985-01-19 | 1985-02-20 | Pfizer Ltd | Dihydropyridine anti-ischaemic & anti-hypertensive agents |
| US4833150A (en) * | 1985-03-14 | 1989-05-23 | Nelson Research & Development Co. | 1,4-dihydropyridines |
| JPS61227567A (ja) * | 1985-04-01 | 1986-10-09 | Eisai Co Ltd | １，４−ジヒドロピリジン誘導体 |
| HU199796B (en) * | 1985-08-06 | 1990-03-28 | Boehringer Biochemia Srl | Process for producing 2-thiomethyl-substituted-1,4-dihydropyridines and pharmaceutical compositions comprising such compounds |
| IT1201454B (it) * | 1985-08-19 | 1989-02-02 | Boehringer Biochemia Srl | 1,4-diidropiridine-2-sostituite |
| GB8526411D0 (en) * | 1985-10-25 | 1985-11-27 | Pfizer Ltd | Dihydropyridines |
| GB8527698D0 (en) * | 1985-11-09 | 1985-12-11 | Pfizer Ltd | Dihydropyridine antiischaemic & antihypertensive agents |
| EP0225175A3 (de) * | 1985-11-28 | 1988-12-28 | FISONS plc | Dihydropyridin-Derivate, Verfahren zu ihrer Herstellung und diese enthaltende pharmazeutische Zusammensetzungen |
| US4654372A (en) * | 1986-01-10 | 1987-03-31 | Warner-Lambert Company | Method for using verapamil for treating stroke |
| US4849436A (en) * | 1986-03-11 | 1989-07-18 | Nelson Research & Development Co. | 1,4-dihydropyridines |
| IT1197012B (it) * | 1986-07-29 | 1988-11-25 | Boehringer Biochemia Srl | 2-(aciltio) metil diidropiridine, un processo per la loro preparazione e composizioni farmaceutiche che le contengono |
| GB8710493D0 (en) * | 1987-05-02 | 1987-06-03 | Pfizer Ltd | Dihydropyridines |
| US20070066619A1 (en) * | 2002-10-07 | 2007-03-22 | Artesian Therapeutics, Inc. | Compounds having simultaneous ability to block L-type calcium channels and to inhibit phosphodiesterase type 3 activity |
| PL376405A1 (en) * | 2002-10-07 | 2005-12-27 | Artesian Therapeutics, Inc. | Dihydropyridine compounds having simultaneous ability to block l-type calcium channels and to inhibit phosphodiesterase type 3 activity |
| WO2006053227A2 (en) * | 2004-11-10 | 2006-05-18 | Synta Pharmaceuticals Corp. | Il-12 modulatory compounds |
| CN115557883A (zh) * | 2022-10-28 | 2023-01-03 | 常州制药厂有限公司 | 一种氨氯地平的合成工艺 |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CS228917B2 (en) * | 1981-03-14 | 1984-05-14 | Pfizer | Method of preparing substituted derivatives of 1,4-dihydropyridine |
| NZ201395A (en) * | 1981-07-30 | 1987-02-20 | Bayer Ag | Pharmaceutical compositions containing 1,4-dihydropyridines and certain of these dihydropyridines |
| DE3363743D1 (en) * | 1982-07-22 | 1986-07-03 | Pfizer Ltd | Dihydropyridine anti-ischaemic and antihypertensive agents |
| PH19166A (en) * | 1982-09-04 | 1986-01-16 | Pfizer | Dihydropyridined,pharmaceutical compositions and method of use |
| EP0107293A3 (de) * | 1982-09-04 | 1984-06-06 | Pfizer Limited | Dihydropyridine |
| GB8414518D0 (en) * | 1984-06-07 | 1984-07-11 | Pfizer Ltd | Therapeutic agents |
-
1984
- 1984-06-21 US US06/623,265 patent/US4568677A/en not_active Expired - Lifetime
- 1984-07-18 DE DE8484304888T patent/DE3478746D1/de not_active Expired
- 1984-07-18 AT AT84304888T patent/ATE44146T1/de not_active IP Right Cessation
- 1984-07-18 EP EP84304888A patent/EP0132375B1/de not_active Expired
- 1984-07-19 CS CS845570A patent/CS241549B2/cs unknown
- 1984-07-19 FI FI842911A patent/FI79105C/fi not_active IP Right Cessation
- 1984-07-20 PH PH31017A patent/PH20479A/en unknown
- 1984-07-20 CA CA000459336A patent/CA1265796A/en not_active Expired - Fee Related
- 1984-07-20 NO NO842987A patent/NO161174C/no not_active IP Right Cessation
- 1984-07-20 PL PL1984248857A patent/PL142659B1/pl unknown
- 1984-07-20 DK DK355784A patent/DK170069B1/da not_active IP Right Cessation
- 1984-07-20 GR GR75382A patent/GR82230B/el unknown
- 1984-07-20 IL IL72475A patent/IL72475A/xx not_active IP Right Cessation
- 1984-07-20 ES ES534505A patent/ES8700856A1/es not_active Expired
- 1984-07-20 NZ NZ208954A patent/NZ208954A/xx unknown
- 1984-07-20 PT PT78958A patent/PT78958B/pt unknown
- 1984-07-20 DD DD84265515A patent/DD226285A5/de not_active IP Right Cessation
- 1984-07-20 HU HU842823A patent/HU212133B/hu not_active IP Right Cessation
- 1984-07-20 AU AU30899/84A patent/AU547188B2/en not_active Ceased
- 1984-07-23 YU YU1305/84A patent/YU43738B/xx unknown
- 1984-07-23 IE IE190584A patent/IE58443B1/en not_active IP Right Cessation
Also Published As
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| B1 | Patent granted (law 1993) | ||
| PBP | Patent lapsed |