DK169975B1 - Rekombinant DNA-molekyle, ekspressionsvektor omfattende samme, værtscelle transformeret med ekspressionsvektoren, fusionsprotein og fremgangsmåde til frembringelse af samme - Google Patents

Rekombinant DNA-molekyle, ekspressionsvektor omfattende samme, værtscelle transformeret med ekspressionsvektoren, fusionsprotein og fremgangsmåde til frembringelse af samme Download PDF

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Publication number
DK169975B1
DK169975B1 DK038189A DK38189A DK169975B1 DK 169975 B1 DK169975 B1 DK 169975B1 DK 038189 A DK038189 A DK 038189A DK 38189 A DK38189 A DK 38189A DK 169975 B1 DK169975 B1 DK 169975B1
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Prior art keywords
glutathione
fusion protein
enzyme
protein
expression vector
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DK038189A
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Danish (da)
English (en)
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DK38189A (da
DK38189D0 (da
Inventor
Danold Bruce Smith
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Amrad Corp Ltd
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Publication of DK38189A publication Critical patent/DK38189A/da
Publication of DK38189D0 publication Critical patent/DK38189D0/da
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Publication of DK169975B1 publication Critical patent/DK169975B1/da

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    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/10—Transferases (2.)
    • C12N9/1085—Transferases (2.) transferring alkyl or aryl groups other than methyl groups (2.5)
    • C12N9/1088—Glutathione transferase (2.5.1.18)
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/43504—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from invertebrates
    • C07K14/43536—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from invertebrates from worms
    • C07K14/43559—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from invertebrates from worms from trematodes
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C12N15/62—DNA sequences coding for fusion proteins
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C07K2319/20—Fusion polypeptide containing a tag with affinity for a non-protein ligand
    • C07K2319/23—Fusion polypeptide containing a tag with affinity for a non-protein ligand containing a GST-tag
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C07K2319/50—Fusion polypeptide containing protease site

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Molecular Biology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • Biophysics (AREA)
  • Microbiology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Medicinal Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Toxicology (AREA)
  • Plant Pathology (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
DK038189A 1987-05-28 1989-01-27 Rekombinant DNA-molekyle, ekspressionsvektor omfattende samme, værtscelle transformeret med ekspressionsvektoren, fusionsprotein og fremgangsmåde til frembringelse af samme DK169975B1 (da)

Applications Claiming Priority (6)

Application Number Priority Date Filing Date Title
AUPI219587 1987-05-28
AUPI219587 1987-05-28
AU1793288 1988-05-27
AU17932/88A AU607511B2 (en) 1987-05-28 1988-05-27 Novel fusion proteins containing glutathione-s-transferase
PCT/AU1988/000164 WO1988009372A1 (en) 1987-05-28 1988-05-27 Novel fusion proteins containing glutathione-s-transferase
AU8800164 1988-05-27

Publications (3)

Publication Number Publication Date
DK38189A DK38189A (da) 1989-01-27
DK38189D0 DK38189D0 (da) 1989-01-27
DK169975B1 true DK169975B1 (da) 1995-04-18

Family

ID=3772204

Family Applications (1)

Application Number Title Priority Date Filing Date
DK038189A DK169975B1 (da) 1987-05-28 1989-01-27 Rekombinant DNA-molekyle, ekspressionsvektor omfattende samme, værtscelle transformeret med ekspressionsvektoren, fusionsprotein og fremgangsmåde til frembringelse af samme

Country Status (14)

Country Link
EP (1) EP0293249B1 (de)
JP (1) JPH0681596B2 (de)
AT (1) ATE79902T1 (de)
AU (1) AU607511B2 (de)
CA (1) CA1338903C (de)
DE (1) DE3873989T2 (de)
DK (1) DK169975B1 (de)
ES (1) ES2045115T3 (de)
GR (1) GR3006173T3 (de)
NO (1) NO178894C (de)
NZ (1) NZ224663A (de)
SG (1) SG25093G (de)
WO (1) WO1988009372A1 (de)
ZA (1) ZA883681B (de)

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JPH04507235A (ja) * 1989-01-31 1992-12-17 ダラテック　ピーテーワイ　リミテッド 反芻動物における肝吸虫感染に対する予防治療のためのワクチン
US5171670A (en) * 1989-05-12 1992-12-15 The General Hospital Corporation Recombinant dna method for production of parathyroid hormone
USRE37919E1 (en) 1989-05-12 2002-12-03 The General Hospital Corporation Recombinant DNA method for production of parathyroid hormone
FR2657883A1 (de) * 1990-02-07 1991-08-09 Transgene Sa
US6077694A (en) * 1990-09-21 2000-06-20 The United States Of America As Represented By The Department Of Health And Human Services Method for over-expression and rapid purification of biosynthetic proteins
WO1993003157A1 (en) * 1991-07-29 1993-02-18 Dana Farber Cancer Institute Plasmids for the rapid preparation of modified proteins
US5596079A (en) * 1991-12-16 1997-01-21 Smith; James R. Mimetics of senescent cell derived inhibitors of DNA synthesis
US6372249B1 (en) 1991-12-16 2002-04-16 Baylor College Of Medicine Senscent cell-derived inhibitors of DNA synthesis
CA2132321A1 (en) * 1992-03-18 1993-09-30 Donald B. Smith Tripartite fusion proteins of glutathione s-transferase
GB9210337D0 (en) * 1992-05-14 1992-07-01 Univ Court Of The University O Feline leukaemia virus vaccine
AU6172194A (en) * 1993-02-08 1994-08-29 Paravax, Inc. Defective sindbis virus vectors that express (toxoplasma gondii) p30 antigens
US5532142A (en) * 1993-02-12 1996-07-02 Board Of Regents, The University Of Texas System Method of isolation and purification of fusion polypeptides
US5480864A (en) * 1993-08-06 1996-01-02 Shiseido Co., Ltd. Modified maxadilan protein, its preparation and use, and DNA encoding the protein
CA2170641C (en) * 1993-08-30 2011-11-15 James R. Smith Senescent cell-derived inhibitors of dna synthesis
US6303369B1 (en) * 1993-09-30 2001-10-16 Carl Spana Protein expression system
GB9502489D0 (en) * 1995-02-09 1995-03-29 Animal Health Trust Expression of the non-structural protein NS1 of influenza virus and detection of anti-NS1 antibody in serum
US5800811A (en) * 1995-06-06 1998-09-01 Hall; Frederick L. Artificial skin prepared from coclagen matrix containing transforming growth factor-β having a collagen binding site
GB9513683D0 (en) 1995-07-05 1995-09-06 Ciba Geigy Ag Products
SG49993A1 (en) 1995-12-28 1998-06-15 Fujirebio Kk Fused dna sequence fused protein expressed from said fused dna sequence and method for expressing said fused protein
DE19653498C1 (de) * 1996-12-20 1998-07-23 Wolf M Prof Dr Bertling Klonierungsvektor-System mit Fusionssequenz
EP1005654B1 (de) 1997-08-01 2006-04-12 Max-Planck-Gesellschaft zur Förderung der Wissenschaften e.V. Verfahren zur bestimmung von amyloid-ähnlichen fibrillen oder proteinaggregaten
EP1001987B1 (de) 1997-08-01 2010-12-15 Max-Planck-Gesellschaft zur Förderung der Wissenschaften e.V. Zusammensetzung und verfahren zum nachweis von krankheiten in zusammenhang mit der bildung von amyloid-ähnlichen fibrillen oder protein-aggregaten
US6752988B1 (en) 2000-04-28 2004-06-22 New Horizons Diagnostic Corp Method of treating upper resiratory illnesses
US6428784B1 (en) 1997-10-31 2002-08-06 New Horizons Diagnostics Corp Vaginal suppository for treating group B Streptococcus infection
US6406692B1 (en) 1997-10-31 2002-06-18 New Horizons Diagnostics Corp Composition for treatment of an ocular bacterial infection
US6432444B1 (en) 1997-10-31 2002-08-13 New Horizons Diagnostics Corp Use of bacterial phage associated lysing enzymes for treating dermatological infections
US6423299B1 (en) 1997-10-31 2002-07-23 Vincent Fischetti Composition for treatment of a bacterial infection of an upper respiratory tract
US6056954A (en) 1997-10-31 2000-05-02 New Horizons Diagnostics Corp Use of bacterial phage associated lysing enzymers for the prophylactic and therapeutic treatment of various illnesses
US7232576B2 (en) 1997-10-31 2007-06-19 New Horizons Diagnostics Corp Throat lozenge for the treatment of Streptococcus Group A
US6277399B1 (en) 1997-10-31 2001-08-21 New Horizon Diagnostics Corporation Composition incorporating bacterial phage associated lysing enzymes for treating dermatological infections
US6077689A (en) * 1997-12-24 2000-06-20 Amgen Inc. Enhanced solubility of recombinant proteins
US6187558B1 (en) 1998-06-24 2001-02-13 Boyce Thompson Institute For Plant Research, Inc. Invertebrate intestinal mucin cDNA and related products and methods
AU4710899A (en) * 1998-06-24 2000-01-10 Boyce Thompson Institute For Plant Research Inc. A novel invertebrate intestinal mucin cdna and related products and methods
GB9821821D0 (en) * 1998-10-07 1998-12-02 Univ Wales Schistomiasis vaccine
US7063837B2 (en) 1999-09-14 2006-06-20 New Horizons Diagnostics Corp Syrup composition containing phage associated lytic enzymes
US6632638B1 (en) 2000-11-17 2003-10-14 Amgen, Inc. Enhanced solubility of recombinant proteins using Uracil DNA glycosylase inhibitor
AU2002317841A1 (en) 2001-06-22 2003-01-08 Roche Diagnostics Gmbh Use of fkbp chaperones as expression tool
US7094757B2 (en) 2001-06-22 2006-08-22 Roche Diagnostics Corporation Complexes comprising a prion protein and a peptidyl prolyl isomerase chaperone, and method for producing and using them
US6962982B2 (en) 2001-06-22 2005-11-08 Roche Diagnostics Corporation Soluble complexes of target proteins and peptidyl prolyl isomerase chaperones and methods of making and using them
ES2255347B1 (es) * 2003-05-21 2007-05-16 Universidad De Vigo Proteina de fusion gst-fucosidasa con actividad enzimatica alfa-l-fucosidasica. proteina recombinante alfa-l-fucosidasa humana.
MY160430A (en) * 2008-12-12 2017-03-15 Univ Sains Malaysia Recombinant antigen for detection of toxocariasis
GB0823550D0 (en) 2008-12-24 2009-01-28 Kinasource Ltd Peptide tag and uses thereof

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU3036684A (en) * 1983-07-07 1985-01-10 Genex Corp. Production of bovine calf chymosin
MA20977A1 (fr) * 1986-05-19 1987-12-31 Ciba Geigy Ag Plantes tolerant les herbicides contenant le gene de gluthathione S-Transferase
AU613583B2 (en) * 1986-08-22 1991-08-08 Transgene S.A. Proteins and the method for preparing them, DNA sequences, antibodies and their application, poxviruses, transformed or infected cells, pharmaceutical compositions which are useful in the prevention of schistosomiasis and application by way of an agent possessing glutathione s-transferase activity
EP0264118B1 (de) * 1986-10-14 1993-08-04 SHIONOGI SEIYAKU KABUSHIKI KAISHA trading under the name of SHIONOGI & CO. LTD. Methode zur Herstellung von Proteinen

Also Published As

Publication number Publication date
ES2045115T3 (es) 1994-01-16
ZA883681B (en) 1989-07-26
JPH0681596B2 (ja) 1994-10-19
EP0293249B1 (de) 1992-08-26
AU607511B2 (en) 1991-03-07
ATE79902T1 (de) 1992-09-15
NO890325D0 (no) 1989-01-26
NZ224663A (en) 1990-11-27
NO890325L (no) 1989-03-06
JPH01503441A (ja) 1989-11-22
DE3873989D1 (de) 1992-10-01
DK38189A (da) 1989-01-27
GR3006173T3 (de) 1993-06-21
DK38189D0 (da) 1989-01-27
EP0293249A1 (de) 1988-11-30
SG25093G (en) 1993-06-11
NO178894B (no) 1996-03-18
AU1793288A (en) 1988-12-21
WO1988009372A1 (en) 1988-12-01
DE3873989T2 (de) 1993-02-04
CA1338903C (en) 1997-02-11
NO178894C (no) 1996-06-26

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