DK169723B1 - Pyrroloquinolin- og pyrrolophenothiazin-carboxamider og beslægtede forbindelser samt farmaceutiske præparater indeholdende disse og deres anvendelse til fremstilling af lægemidler til behandling af inflammation eller andre prostaglandin- eller leukotrin-formidlede sygdomme - Google Patents

Pyrroloquinolin- og pyrrolophenothiazin-carboxamider og beslægtede forbindelser samt farmaceutiske præparater indeholdende disse og deres anvendelse til fremstilling af lægemidler til behandling af inflammation eller andre prostaglandin- eller leukotrin-formidlede sygdomme Download PDF

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Publication number
DK169723B1
DK169723B1 DK116689A DK116689A DK169723B1 DK 169723 B1 DK169723 B1 DK 169723B1 DK 116689 A DK116689 A DK 116689A DK 116689 A DK116689 A DK 116689A DK 169723 B1 DK169723 B1 DK 169723B1
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Denmark
Prior art keywords
carboxamide
thiazolyl
dihydro
compounds
trifluoromethyl
Prior art date
Application number
DK116689A
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Danish (da)
English (en)
Other versions
DK116689D0 (da
DK116689A (da
Inventor
Banavara Lakshmana Mylari
Joseph George Lombardino
James Michael Mcmanus
Original Assignee
Pfizer
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
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Publication date
Application filed by Pfizer filed Critical Pfizer
Publication of DK116689D0 publication Critical patent/DK116689D0/da
Publication of DK116689A publication Critical patent/DK116689A/da
Application granted granted Critical
Publication of DK169723B1 publication Critical patent/DK169723B1/da

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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/06—Peri-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/08—Antiallergic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/06—Peri-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D513/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00
    • C07D513/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00 in which the condensed system contains two hetero rings
    • C07D513/06—Peri-condensed systems

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Pulmonology (AREA)
  • Communicable Diseases (AREA)
  • Immunology (AREA)
  • Oncology (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
DK116689A 1988-03-11 1989-03-10 Pyrroloquinolin- og pyrrolophenothiazin-carboxamider og beslægtede forbindelser samt farmaceutiske præparater indeholdende disse og deres anvendelse til fremstilling af lægemidler til behandling af inflammation eller andre prostaglandin- eller leukotrin-formidlede sygdomme DK169723B1 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US8800781 1988-03-11
PCT/US1988/000781 WO1989008654A1 (en) 1988-03-11 1988-03-11 Pyrroloquinoline and pyrrolophenothiazine carboxamides and related compounds

Publications (3)

Publication Number Publication Date
DK116689D0 DK116689D0 (da) 1989-03-10
DK116689A DK116689A (da) 1989-09-12
DK169723B1 true DK169723B1 (da) 1995-01-23

Family

ID=22208596

Family Applications (1)

Application Number Title Priority Date Filing Date
DK116689A DK169723B1 (da) 1988-03-11 1989-03-10 Pyrroloquinolin- og pyrrolophenothiazin-carboxamider og beslægtede forbindelser samt farmaceutiske præparater indeholdende disse og deres anvendelse til fremstilling af lægemidler til behandling af inflammation eller andre prostaglandin- eller leukotrin-formidlede sygdomme

Country Status (15)

Country Link
EP (1) EP0332364A3 (pt)
JP (1) JPH0676408B2 (pt)
KR (1) KR910002565B1 (pt)
AU (1) AU605410B2 (pt)
CA (1) CA1335592C (pt)
DK (1) DK169723B1 (pt)
FI (1) FI96315C (pt)
HU (1) HU201757B (pt)
IL (1) IL89480A (pt)
MY (1) MY104955A (pt)
NO (1) NO170418C (pt)
NZ (1) NZ228299A (pt)
PT (1) PT89954B (pt)
WO (1) WO1989008654A1 (pt)
ZA (1) ZA891800B (pt)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3907388A1 (de) * 1989-03-08 1990-09-13 Kali Chemie Pharma Gmbh Verfahren zur herstellung von indolcarbonsaeurederivaten
JPH06279444A (ja) * 1993-03-31 1994-10-04 Tokyo Tanabe Co Ltd インドリジン誘導体
US6084098A (en) 1999-02-26 2000-07-04 Neurogen Corporation Benzylpiperazinyl and piperidinyl ethanone derivatives: dopamine receptor subtype specific ligands
CA2321830A1 (en) * 1998-02-26 1999-09-02 Neurogen Corporation Benzylpiperazinyl- and benzylpiperidinyl ethanone derivatives, their preparation and their use as dopamine d4 receptor antagonists
US6284759B1 (en) 1998-09-30 2001-09-04 Neurogen Corporation 2-piperazinoalkylaminobenzo-azole derivatives: dopamine receptor subtype specific ligands
CA2579717A1 (en) * 2004-09-09 2006-03-23 Merck & Co., Inc. Tricyclic anilide spirolactam cgrp receptor antagonists
WO2006031676A2 (en) * 2004-09-13 2006-03-23 Merck & Co., Inc. Tricyclic anilide spirohydantoin cgrp receptor antagonists
US7741317B2 (en) * 2005-10-21 2010-06-22 Bristol-Myers Squibb Company LXR modulators
CN108853102B (zh) * 2017-05-15 2021-04-09 北京大学 作用于Dectin-1的稠合吖啶衍生物及其用途

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1394373A (en) * 1972-05-17 1975-05-14 Pfizer Ltd Control of plant diseases
ATE34392T1 (de) * 1983-10-17 1988-06-15 Synthelabo Imidazolinderivate, ihre herstellung und therapeutische verwendung.
FR2567126B1 (fr) * 1984-07-06 1986-12-12 Synthelabo Derives de pyrrolo(1,2,3-de) benzoxazine et benzothiazine, leur preparation et leur application en therapeutique
JPS6317885A (ja) * 1986-07-11 1988-01-25 Kyorin Pharmaceut Co Ltd スピロピロリジン−２，５−ジオン誘導体の製造方法

Also Published As

Publication number Publication date
IL89480A0 (en) 1989-09-10
NO170418C (no) 1992-10-14
DK116689D0 (da) 1989-03-10
HU885829D0 (en) 1990-02-28
AU605410B2 (en) 1991-01-10
IL89480A (en) 1994-04-12
FI96315B (fi) 1996-02-29
ZA891800B (en) 1990-10-31
NO894350D0 (no) 1989-11-01
DK116689A (da) 1989-09-12
PT89954B (pt) 1994-05-31
FI895333A0 (fi) 1989-11-09
HU201757B (en) 1990-12-28
KR890014545A (ko) 1989-10-24
KR910002565B1 (ko) 1991-04-26
NO894350L (no) 1989-11-01
CA1335592C (en) 1995-05-16
JPH01275580A (ja) 1989-11-06
EP0332364A2 (en) 1989-09-13
WO1989008654A1 (en) 1989-09-21
FI96315C (fi) 1996-06-10
EP0332364A3 (en) 1991-04-03
MY104955A (en) 1994-07-30
JPH0676408B2 (ja) 1994-09-28
NO170418B (no) 1992-07-06
AU3120489A (en) 1989-09-14
NZ228299A (en) 1990-09-26
PT89954A (pt) 1989-11-10

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Legal Events

Date Code Title Description
B1 Patent granted (law 1993)
PBP Patent lapsed