DK169340B1 - Analogifremgangsmåde til fremstilling af nitrosoureaderivater - Google Patents

Analogifremgangsmåde til fremstilling af nitrosoureaderivater Download PDF

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Publication number
DK169340B1
DK169340B1 DK524283A DK524283A DK169340B1 DK 169340 B1 DK169340 B1 DK 169340B1 DK 524283 A DK524283 A DK 524283A DK 524283 A DK524283 A DK 524283A DK 169340 B1 DK169340 B1 DK 169340B1
Authority
DK
Denmark
Prior art keywords
formula
derivatives
chloroethyl
animals
preparation
Prior art date
Application number
DK524283A
Other languages
Danish (da)
English (en)
Other versions
DK524283D0 (da
DK524283A (da
Inventor
Gilbert Lavielle
Claude Cudennec
Original Assignee
Adir
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Adir filed Critical Adir
Publication of DK524283D0 publication Critical patent/DK524283D0/da
Publication of DK524283A publication Critical patent/DK524283A/da
Application granted granted Critical
Publication of DK169340B1 publication Critical patent/DK169340B1/da

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic System
    • C07F9/02—Phosphorus compounds
    • C07F9/28—Phosphorus compounds with one or more P—C bonds
    • C07F9/38—Phosphonic acids RP(=O)(OH)2; Thiophosphonic acids, i.e. RP(=X)(XH)2 (X = S, Se)
    • C07F9/3804—Phosphonic acids RP(=O)(OH)2; Thiophosphonic acids, i.e. RP(=X)(XH)2 (X = S, Se) not used, see subgroups
    • C07F9/3808—Acyclic saturated acids which can have further substituents on alkyl
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic System
    • C07F9/02—Phosphorus compounds
    • C07F9/28—Phosphorus compounds with one or more P—C bonds
    • C07F9/38—Phosphonic acids RP(=O)(OH)2; Thiophosphonic acids, i.e. RP(=X)(XH)2 (X = S, Se)
    • C07F9/40—Esters thereof
    • C07F9/4003—Esters thereof the acid moiety containing a substituent or a structure which is considered as characteristic
    • C07F9/4006—Esters of acyclic acids which can have further substituents on alkyl

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Heterocyclic Compounds Containing Sulfur Atoms (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
DK524283A 1982-11-17 1983-11-16 Analogifremgangsmåde til fremstilling af nitrosoureaderivater DK169340B1 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR8219199 1982-11-17
FR8219199A FR2536075B1 (fr) 1982-11-17 1982-11-17 Nouveaux derives de la nitrosouree, leur procede de preparation et les compositions pharmaceutiques les renfermant

Publications (3)

Publication Number Publication Date
DK524283D0 DK524283D0 (da) 1983-11-16
DK524283A DK524283A (da) 1984-05-18
DK169340B1 true DK169340B1 (da) 1994-10-10

Family

ID=9279241

Family Applications (1)

Application Number Title Priority Date Filing Date
DK524283A DK169340B1 (da) 1982-11-17 1983-11-16 Analogifremgangsmåde til fremstilling af nitrosoureaderivater

Country Status (19)

Country Link
US (1) US4567169A (no)
EP (1) EP0117959B1 (no)
JP (1) JPS59106497A (no)
AT (1) ATE21905T1 (no)
AU (1) AU557139B2 (no)
CA (1) CA1204442A (no)
DE (1) DE3365900D1 (no)
DK (1) DK169340B1 (no)
ES (1) ES8501772A1 (no)
FR (1) FR2536075B1 (no)
IE (1) IE56259B1 (no)
IL (1) IL70253A (no)
MA (1) MA19952A1 (no)
NO (1) NO163409C (no)
NZ (1) NZ206293A (no)
OA (1) OA07589A (no)
PT (1) PT77666B (no)
SU (1) SU1303024A3 (no)
ZA (1) ZA838558B (no)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2567129B1 (fr) * 1984-07-06 1986-12-05 Adir Nouveaux derives de l'oxaazaphosphorine, leur procede de preparation et les compositions pharmaceutiques les renfermant
IT1246778B (it) * 1991-04-12 1994-11-26 Boehringer Mannheim Italia Nitrosocarbamoil derivati di acidi gem-difosfonici, un processo per la loro preparazione e composizioni farmaceutiche che li contengono
US5298499A (en) * 1991-07-05 1994-03-29 Research Triangle Institute S-2-(substituted ethylamino)ethyl phosphorothioates
WO1997018819A1 (en) * 1995-11-20 1997-05-29 Sepracor, Inc. Antineoplastic methods and compositions employing optically pure (-)-fotemustine
JP2000500495A (ja) * 1995-11-20 2000-01-18 セプラコール，インク． （＋）−フォテムスチンを用いる新生物を治療するための方法および組成物
US20040072889A1 (en) * 1997-04-21 2004-04-15 Pharmacia Corporation Method of using a COX-2 inhibitor and an alkylating-type antineoplastic agent as a combination therapy in the treatment of neoplasia
CN100365002C (zh) * 2004-06-02 2008-01-30 上海医药科技发展有限公司 注射用福莫司汀制备工艺
AT501496B1 (de) * 2005-02-21 2007-03-15 Iep Gmbh Verfahren zur enantioselektiven enzymatischen reduktion von ketoverbindungen
CN102311456A (zh) * 2011-07-08 2012-01-11 山东睿鹰先锋制药有限公司 一种福莫司汀原料药的合成方法

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3920733A (en) * 1973-08-06 1975-11-18 Monsanto Co Ureidoalkylphosphonic acids

Also Published As

Publication number Publication date
DK524283D0 (da) 1983-11-16
FR2536075A1 (fr) 1984-05-18
ES527353A0 (es) 1984-12-01
ES8501772A1 (es) 1984-12-01
PT77666B (fr) 1986-05-12
AU557139B2 (en) 1986-12-04
IE832680L (en) 1984-05-17
NO163409B (no) 1990-02-12
ATE21905T1 (de) 1986-09-15
DK524283A (da) 1984-05-18
ZA838558B (en) 1984-07-25
NZ206293A (en) 1987-02-20
FR2536075B1 (fr) 1985-07-05
SU1303024A3 (ru) 1987-04-07
IL70253A (en) 1986-10-31
EP0117959B1 (fr) 1986-09-03
EP0117959A2 (fr) 1984-09-12
JPS59106497A (ja) 1984-06-20
CA1204442A (fr) 1986-05-13
IE56259B1 (en) 1991-06-05
AU2143683A (en) 1984-05-24
JPS6411637B2 (no) 1989-02-27
NO834214L (no) 1984-05-18
OA07589A (fr) 1985-03-31
MA19952A1 (fr) 1984-07-01
PT77666A (fr) 1983-12-01
IL70253A0 (en) 1984-02-29
NO163409C (no) 1990-05-23
DE3365900D1 (en) 1986-10-09
US4567169A (en) 1986-01-28
EP0117959A3 (en) 1984-11-14

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Legal Events

Date Code Title Description
B1 Patent granted (law 1993)
PUP Patent expired