DK169185A - Dihydropyridin-3,5-dicarboxylsyreesterderivater, fremgangsmaade tilfremstilling heraf og farmaceutiske praeparater indeholdende disse - Google Patents

Dihydropyridin-3,5-dicarboxylsyreesterderivater, fremgangsmaade tilfremstilling heraf og farmaceutiske praeparater indeholdende disse Download PDF

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Publication number
DK169185A
DK169185A DK169185A DK169185A DK169185A DK 169185 A DK169185 A DK 169185A DK 169185 A DK169185 A DK 169185A DK 169185 A DK169185 A DK 169185A DK 169185 A DK169185 A DK 169185A
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DK
Denmark
Prior art keywords
dihydropyridine
diastereoisomer
preparation
acid ester
pharmaceutical preparations
Prior art date
Application number
DK169185A
Other languages
English (en)
Other versions
DK166386B (da
DK166386C (da
DK169185D0 (da
Inventor
Kazuharu Tamazawa
Tadao Kojima
Hideki Arima
Yukiyasu Murakami
Isomura Yasuo
Minoru Okada
Kiyoshi Takanobu
Toichi Takenaka
Original Assignee
Yamanouchi Pharma Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from JP7599884A external-priority patent/JPS60231673A/ja
Priority claimed from JP59114098A external-priority patent/JPS60258179A/ja
Priority claimed from JP59165793A external-priority patent/JPS6143187A/ja
Application filed by Yamanouchi Pharma Co Ltd filed Critical Yamanouchi Pharma Co Ltd
Publication of DK169185D0 publication Critical patent/DK169185D0/da
Publication of DK169185A publication Critical patent/DK169185A/da
Publication of DK166386B publication Critical patent/DK166386B/da
Application granted granted Critical
Publication of DK166386C publication Critical patent/DK166386C/da

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Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D401/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/12Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D207/00Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D207/02Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D207/18Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member
    • C07D207/22Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D207/24Oxygen or sulfur atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D211/00Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/80Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members
    • C07D211/84Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen directly attached to ring carbon atoms
    • C07D211/90Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Hydrogenated Pyridines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Plural Heterocyclic Compounds (AREA)
DK169185A 1984-04-16 1985-04-15 Diastereoisomer a af 2,6-dimethyl-4-(3-nitrophenyl)-1,4-dihydropyridin-3,5-dicarboxylsyre-3-(1-benzylpyrrolidin-3-yl)ester-5-methylester, den hoejredrejende optiske isomer heraf, fremgangsmaader til fremstilling af forbindelserne og farmaceutiske praeparater indeholdende disse DK166386C (da)

Applications Claiming Priority (6)

Application Number Priority Date Filing Date Title
JP7599884 1984-04-16
JP7599884A JPS60231673A (ja) 1984-04-16 1984-04-16 Ym−09730のジアステレオマーaまたはその酸付加塩、該化合物の製造方法および該化合物からなる医薬
JP11409884 1984-06-04
JP59114098A JPS60258179A (ja) 1984-06-04 1984-06-04 Ym−09730のジアステレオマ−aの右旋性光学異性体またはその酸付加塩,該化合物の製造方法および該化合物からなる医薬
JP16579384 1984-08-07
JP59165793A JPS6143187A (ja) 1984-08-07 1984-08-07 Ym−09730のジアステレオマ−aの右旋性光学異性体の新規製法

Publications (4)

Publication Number Publication Date
DK169185D0 DK169185D0 (da) 1985-04-15
DK169185A true DK169185A (da) 1985-10-17
DK166386B DK166386B (da) 1993-05-10
DK166386C DK166386C (da) 1993-09-27

Family

ID=27302015

Family Applications (1)

Application Number Title Priority Date Filing Date
DK169185A DK166386C (da) 1984-04-16 1985-04-15 Diastereoisomer a af 2,6-dimethyl-4-(3-nitrophenyl)-1,4-dihydropyridin-3,5-dicarboxylsyre-3-(1-benzylpyrrolidin-3-yl)ester-5-methylester, den hoejredrejende optiske isomer heraf, fremgangsmaader til fremstilling af forbindelserne og farmaceutiske praeparater indeholdende disse

Country Status (13)

Country Link
EP (1) EP0160451B1 (da)
KR (1) KR920003626B1 (da)
AT (1) ATE66677T1 (da)
AU (1) AU569618B2 (da)
CA (2) CA1273930A (da)
DE (1) DE3583882D1 (da)
DK (1) DK166386C (da)
ES (4) ES8608512A1 (da)
GR (1) GR850872B (da)
IE (1) IE57811B1 (da)
MX (1) MX7363E (da)
NL (1) NL990023I2 (da)
NO (1) NO159594C (da)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9405833D0 (en) * 1994-03-24 1994-05-11 Pfizer Ltd Separation of the enantiomers of amlodipine
DE4443168A1 (de) * 1994-12-05 1996-06-13 Bayer Ag Neues hochselektives Verfahren zur Herstellung von enantiomerenreinen phenylsubstituierten 1,4-Dihydropyridin-3,5-dicarbonsäurederivaten
KR100939347B1 (ko) 2005-07-20 2010-01-29 (주)카이로드 광학적으로 순수한 (s)-3-히드록시 피롤리딘의 제조방법
ITMI20120513A1 (it) * 2012-03-29 2013-09-30 Lusochimica Spa Nuove forme polimorfe della barnidipina cloridrato e processi per la loro preparazione
EP4382529A1 (en) 2022-12-07 2024-06-12 Bayer Consumer Care AG A process for preparing pure (3s)-pyrrolidin-3-ol and pure (3s)-pyrrolidin-3-ol hydrochloride

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS55301A (en) * 1978-02-14 1980-01-05 Yamanouchi Pharmaceut Co Ltd 1,4-dihydropyridine-3,5-dicarboxylic ester derivative and its preparation

Also Published As

Publication number Publication date
AU569618B2 (en) 1988-02-11
IE850985L (en) 1985-10-25
IE57811B1 (en) 1993-04-21
NO851494L (no) 1985-10-17
MX7363E (es) 1988-08-04
ES8707522A1 (es) 1987-08-01
DK166386B (da) 1993-05-10
EP0160451B1 (en) 1991-08-28
EP0160451A3 (en) 1987-07-08
NO159594C (no) 1989-01-18
ATE66677T1 (de) 1991-09-15
ES542253A0 (es) 1986-07-01
NL990023I1 (nl) 1999-10-01
ES8704937A1 (es) 1987-04-16
DE3583882D1 (da) 1991-10-02
ES8608512A1 (es) 1986-07-01
KR860008162A (ko) 1986-11-12
ES8704866A1 (es) 1987-04-16
GR850872B (da) 1985-11-25
ES551767A0 (es) 1987-04-16
NO159594B (no) 1988-10-10
NL990023I2 (nl) 1999-12-01
EP0160451A2 (en) 1985-11-06
AU4131885A (en) 1985-10-24
DK166386C (da) 1993-09-27
DK169185D0 (da) 1985-04-15
ES551769A0 (es) 1987-04-16
KR920003626B1 (ko) 1992-05-04
CA1289565C (en) 1991-09-24
CA1273930A (en) 1990-09-11
ES551768A0 (es) 1987-08-01

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Legal Events

Date Code Title Description
B1 Patent granted (law 1993)
PUP Patent expired