DK168707B1 - 3-(2-halogenalkyl)-1,4-oxathiiner og 2-(2-halogenalkyl)-1,4-dithiiner, farmaceutiske præparater indeholdende disse, samt anvendelse deraf - Google Patents

3-(2-halogenalkyl)-1,4-oxathiiner og 2-(2-halogenalkyl)-1,4-dithiiner, farmaceutiske præparater indeholdende disse, samt anvendelse deraf Download PDF

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Publication number
DK168707B1
DK168707B1 DK131188A DK131188A DK168707B1 DK 168707 B1 DK168707 B1 DK 168707B1 DK 131188 A DK131188 A DK 131188A DK 131188 A DK131188 A DK 131188A DK 168707 B1 DK168707 B1 DK 168707B1
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DK
Denmark
Prior art keywords
compound according
compound
leukemia
oxathiin
tumors
Prior art date
Application number
DK131188A
Other languages
Danish (da)
English (en)
Other versions
DK131188D0 (da
DK131188A (da
Inventor
Walter Gerhard Brouwer
Ethel Ellen Felauer
Marshal Kulka
Original Assignee
Uniroyal Chemical Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Uniroyal Chemical Ltd filed Critical Uniroyal Chemical Ltd
Publication of DK131188D0 publication Critical patent/DK131188D0/da
Publication of DK131188A publication Critical patent/DK131188A/da
Application granted granted Critical
Publication of DK168707B1 publication Critical patent/DK168707B1/da

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    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D339/00Heterocyclic compounds containing rings having two sulfur atoms as the only ring hetero atoms
    • C07D339/08Six-membered rings
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • A61P35/02Antineoplastic agents specific for leukemia
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D327/00Heterocyclic compounds containing rings having oxygen and sulfur atoms as the only ring hetero atoms
    • C07D327/02Heterocyclic compounds containing rings having oxygen and sulfur atoms as the only ring hetero atoms one oxygen atom and one sulfur atom
    • C07D327/06Six-membered rings

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  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Hematology (AREA)
  • Oncology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Heterocyclic Compounds Containing Sulfur Atoms (AREA)
DK131188A 1987-03-11 1988-03-10 3-(2-halogenalkyl)-1,4-oxathiiner og 2-(2-halogenalkyl)-1,4-dithiiner, farmaceutiske præparater indeholdende disse, samt anvendelse deraf DK168707B1 (da)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US2465787A 1987-03-11 1987-03-11
US2465787 1987-03-11
US07/146,512 US4822813A (en) 1987-03-11 1988-01-21 3-(2-Haloalkyl)-1,4-oxathiins and 2-(2-haloalkyl)-1,4-dithiins, and treatment of leukemia and tumors therewith
US14651288 1988-01-21

Publications (3)

Publication Number Publication Date
DK131188D0 DK131188D0 (da) 1988-03-10
DK131188A DK131188A (da) 1988-09-12
DK168707B1 true DK168707B1 (da) 1994-05-24

Family

ID=26698721

Family Applications (1)

Application Number Title Priority Date Filing Date
DK131188A DK168707B1 (da) 1987-03-11 1988-03-10 3-(2-halogenalkyl)-1,4-oxathiiner og 2-(2-halogenalkyl)-1,4-dithiiner, farmaceutiske præparater indeholdende disse, samt anvendelse deraf

Country Status (20)

Country Link
US (1) US4822813A (de)
JP (1) JPS63264580A (de)
AT (1) AT397089B (de)
AU (1) AU597478B2 (de)
BE (1) BE1002181A3 (de)
CA (1) CA1320210C (de)
CH (1) CH674366A5 (de)
DE (1) DE3808024A1 (de)
DK (1) DK168707B1 (de)
ES (1) ES2011075A6 (de)
FR (1) FR2612188B1 (de)
GB (1) GB2201958B (de)
GR (1) GR1000238B (de)
IE (1) IE61955B1 (de)
IL (1) IL85517A (de)
IT (1) IT8819726A0 (de)
LU (1) LU87152A1 (de)
NL (1) NL8800531A (de)
NZ (1) NZ223798A (de)
SE (1) SE466400B (de)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9001327D0 (en) * 1990-01-19 1990-03-21 May & Baker Ltd New compositions of matter
IL103586A (en) * 1991-10-30 1997-09-30 Astra Ab Process for the preparation of 4-methyl-5- (2-chloroethyl)-thiazole and analogues thereof
CN106278845B (zh) * 2016-05-19 2019-03-05 海正化工南通有限公司 一种3,5-二氯-2-戊酮的合成工艺
CN106565441A (zh) * 2016-11-10 2017-04-19 安徽国星生物化学有限公司 一种3,5‑二氯‑2‑戊酮的合成方法
CN106673978B (zh) * 2016-11-30 2019-06-25 湖南化工研究院有限公司 3,5-二氯-2-戊酮的连续化合成方法
CN107473949B (zh) * 2017-09-26 2020-10-02 安徽国星生物化学有限公司 一种3,5-二氯-2-戊酮的合成工艺

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3868459A (en) * 1968-05-21 1975-02-25 Aquitaine Petrole Method of killing nematodes using certain halomethyl oxathienes
US3728357A (en) * 1970-09-08 1973-04-17 Uniroyal Inc 2-(substituted-methyl)-5,6-dihydro-1,4-oxathiin-3-carboxamides
US4319003A (en) * 1980-09-26 1982-03-09 General Motors Corporation Poly(methyl methacrylate) polycarbonate block copolymers

Also Published As

Publication number Publication date
BE1002181A3 (fr) 1990-10-02
SE466400B (sv) 1992-02-10
IE880597L (en) 1988-09-11
FR2612188B1 (fr) 1991-02-15
LU87152A1 (fr) 1988-11-17
FR2612188A1 (fr) 1988-09-16
CA1320210C (en) 1993-07-13
GB8804454D0 (en) 1988-03-23
AU1282788A (en) 1988-09-15
AT397089B (de) 1994-01-25
GR1000238B (el) 1992-05-12
DE3808024A1 (de) 1988-09-22
ES2011075A6 (es) 1989-12-16
IT8819726A0 (it) 1988-03-10
IE61955B1 (en) 1994-11-30
NZ223798A (en) 1989-12-21
GB2201958B (en) 1990-10-10
IL85517A (en) 1992-09-06
NL8800531A (nl) 1988-10-03
ATA67688A (de) 1993-06-15
DK131188D0 (da) 1988-03-10
DK131188A (da) 1988-09-12
JPH0372221B2 (de) 1991-11-18
IL85517A0 (en) 1988-08-31
SE8800863L (sv) 1989-09-12
CH674366A5 (de) 1990-05-31
US4822813A (en) 1989-04-18
GB2201958A (en) 1988-09-14
JPS63264580A (ja) 1988-11-01
AU597478B2 (en) 1990-05-31
GR880100136A (en) 1989-01-31
SE8800863D0 (sv) 1988-03-10

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Legal Events

Date Code Title Description
B1 Patent granted (law 1993)
PBP Patent lapsed