DK167649B1 - Fast laegemiddeldispersion med forlaenget afgivelse, sekundaer struktur af laegemidlet samt farmaceutisk praeparat indeholdende dispersionen eller strukturen - Google Patents

Fast laegemiddeldispersion med forlaenget afgivelse, sekundaer struktur af laegemidlet samt farmaceutisk praeparat indeholdende dispersionen eller strukturen Download PDF

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Publication number
DK167649B1
DK167649B1 DK264785A DK264785A DK167649B1 DK 167649 B1 DK167649 B1 DK 167649B1 DK 264785 A DK264785 A DK 264785A DK 264785 A DK264785 A DK 264785A DK 167649 B1 DK167649 B1 DK 167649B1
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DK
Denmark
Prior art keywords
active agent
dispersion
compound
pharmaceutical composition
hours
Prior art date
Application number
DK264785A
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Danish (da)
English (en)
Other versions
DK264785D0 (da
DK264785A (da
Inventor
Wolfgang Czarnecki
Jean Claude Gfeller
Hans Peter Bier
Original Assignee
Sandoz Ag
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Publication date
Application filed by Sandoz Ag filed Critical Sandoz Ag
Publication of DK264785D0 publication Critical patent/DK264785D0/da
Publication of DK264785A publication Critical patent/DK264785A/da
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Publication of DK167649B1 publication Critical patent/DK167649B1/da

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Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44Non condensed pyridines; Hydrogenated derivatives thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/14Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/141Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers
    • A61K9/146Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers with organic macromolecular compounds
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/20Pills, tablets, discs, rods
    • A61K9/2004Excipients; Inactive ingredients
    • A61K9/2022Organic macromolecular compounds
    • A61K9/2031Organic macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyethylene glycol, polyethylene oxide, poloxamers

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  • Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
DK264785A 1984-06-14 1985-06-12 Fast laegemiddeldispersion med forlaenget afgivelse, sekundaer struktur af laegemidlet samt farmaceutisk praeparat indeholdende dispersionen eller strukturen DK167649B1 (da)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
DE3422083 1984-06-14
DE3422083 1984-06-14
DE3442566 1984-11-22
DE3442566 1984-11-22

Publications (3)

Publication Number Publication Date
DK264785D0 DK264785D0 (da) 1985-06-12
DK264785A DK264785A (da) 1985-12-15
DK167649B1 true DK167649B1 (da) 1993-12-06

Family

ID=25822108

Family Applications (1)

Application Number Title Priority Date Filing Date
DK264785A DK167649B1 (da) 1984-06-14 1985-06-12 Fast laegemiddeldispersion med forlaenget afgivelse, sekundaer struktur af laegemidlet samt farmaceutisk praeparat indeholdende dispersionen eller strukturen

Country Status (21)

Country Link
AT (1) AT391806B (nl)
AU (2) AU587190B2 (nl)
BE (1) BE902626A (nl)
CA (1) CA1264441A (nl)
CY (1) CY1635A (nl)
DE (1) DE3520184C2 (nl)
DK (1) DK167649B1 (nl)
ES (1) ES8702141A1 (nl)
FR (1) FR2565822B1 (nl)
GB (3) GB2160100B (nl)
GR (1) GR851430B (nl)
HK (1) HK25192A (nl)
HU (1) HU198844B (nl)
IE (1) IE58834B1 (nl)
IL (1) IL75490A0 (nl)
IT (1) IT1200080B (nl)
LU (1) LU85946A1 (nl)
NL (1) NL194389C (nl)
NZ (1) NZ212390A (nl)
PT (1) PT80635B (nl)
SE (1) SE504583C2 (nl)

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Publication number Priority date Publication date Assignee Title
IT1187751B (it) * 1985-10-15 1987-12-23 Eurand Spa Procedimento per la preparazione di formulazioni solidi di nifedipina ad elevata biodisponibilita' e ad effetto prolungato e formulazioni cosi' ottenute
US4816263A (en) * 1987-10-02 1989-03-28 Alza Corporation Dosage form for treating cardiovascular diseases comprising isradipine
WO1989009066A1 (en) * 1988-03-24 1989-10-05 Bukh Meditec A/S Controlled release composition
GR1000270B (el) * 1988-09-30 1992-05-12 Alza Corp Μορφη δοσολογιας για θεραπεια καρδιαγγειακων ασθενειων.
DK469989D0 (da) * 1989-09-22 1989-09-22 Bukh Meditec Farmaceutisk praeparat
MX9300110A (es) * 1992-01-13 1994-07-29 Gerhard Gergely Preparacion farmaceutica en la forma de una tableta de efervescencia o de desintegracion o de un granulado de tipo instanteneo y procedimiento para su preparacion.
DE4201179A1 (de) * 1992-01-17 1993-07-22 Alfatec Pharma Gmbh Wirkstoff(e) enthaltendes granulat oder pellet mit einem geruest aus hydrophilen makromolekuelen und verfahren zu seiner herstellung
US5773025A (en) 1993-09-09 1998-06-30 Edward Mendell Co., Inc. Sustained release heterodisperse hydrogel systems--amorphous drugs
US6726930B1 (en) 1993-09-09 2004-04-27 Penwest Pharmaceuticals Co. Sustained release heterodisperse hydrogel systems for insoluble drugs
US5455046A (en) * 1993-09-09 1995-10-03 Edward Mendell Co., Inc. Sustained release heterodisperse hydrogel systems for insoluble drugs
GB2281697A (en) * 1993-09-14 1995-03-15 Euro Celtique Sa Laxative compositions in capsules
AU695734B2 (en) 1996-07-08 1998-08-20 Penwest Pharmaceuticals Co. Sustained release matrix for high-dose insoluble drugs
DE19710009A1 (de) * 1997-03-12 1998-09-24 Knoll Ag Mehrphasige wirkstoffhaltige Zubereitungsformen
US6056977A (en) * 1997-10-15 2000-05-02 Edward Mendell Co., Inc. Once-a-day controlled release sulfonylurea formulation
US6787157B1 (en) 1998-03-10 2004-09-07 Abbott Laboratories Multiphase active ingredient-containing formulations
US7001892B1 (en) 1999-06-11 2006-02-21 Purdue Research Foundation Pharmaceutical materials and methods for their preparation and use
AU5483600A (en) * 1999-06-11 2001-01-02 Jean A. Chmielewski Pharmaceutical materials and methods for their preparation and use
HU229295B1 (en) * 1999-08-04 2013-10-28 Astellas Pharma Inc Stable medicinal compositions for oral use
CA2352211C (en) 1999-09-30 2009-03-24 Edward Mendell Co., Inc. Sustained release matrix systems for highly soluble drugs
WO2002064121A1 (en) * 2001-02-13 2002-08-22 Astrazeneca Ab Novel modified released formulation
US7135436B2 (en) 2003-05-05 2006-11-14 J.F. Daley International, Ltd. Solid algicide, preparation and usage in recirculating water
EP1690528A1 (de) 2005-02-11 2006-08-16 Abbott GmbH & Co. KG Herstellung von Dosierungsformen mit einer festen Dispersion eines mikrokristallinen Wirkstoffs
WO2008070118A1 (en) 2006-12-05 2008-06-12 Landec Corporation Drug delivery
US8399007B2 (en) 2006-12-05 2013-03-19 Landec Corporation Method for formulating a controlled-release pharmaceutical formulation
US8114883B2 (en) 2007-12-04 2012-02-14 Landec Corporation Polymer formulations for delivery of bioactive materials
US9192578B2 (en) * 2008-08-20 2015-11-24 Board Of Regents, The University Of Texas System Hot-melt extrusion of modified release multi-particulates

Family Cites Families (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE1617362A1 (de) * 1967-11-17 1971-03-25 Beiersdorf Ag Verfahren zur Herstellung von Arzneimitteln mit verzoegerter Wirkstoffabgabe in Form von Kapseln
DE2400819C2 (de) * 1974-01-09 1982-04-22 Bayer Ag, 5090 Leverkusen Verfahren zur Herstellung fester Zubereitungen von schwerlöslichen Arzneimittelwirkstoffen in feinster Verteilung
DE2546577B2 (de) * 1975-10-17 1981-04-02 Sandoz-Patent-GmbH, 7850 Lörrach Feste Stoffe aus Polyvinylpyrrolidon und Ergotalkaloiden
GB1504553A (en) * 1975-11-17 1978-03-22 Sandoz Ltd Tablet formulations
GB1579818A (en) * 1977-06-07 1980-11-26 Yamanouchi Pharma Co Ltd Nifedipine-containing solid preparation composition
FI64938C (fi) * 1977-06-20 1984-02-10 Sandoz Ag Foerfarande foer framstaellning av nya terapeutiskt anvaendbara bensoxa- och bensotiadiazolyl-1,4-dihydropyridinderivat
CH639659A5 (de) * 1978-12-18 1983-11-30 Sandoz Ag Neue 1,4-dihydropyridinderivate, deren herstellung und verwendung.
EP0001247A1 (en) * 1977-09-14 1979-04-04 Kanebo, Ltd. Pharmaceutical preparation containing nifedipine and a method for producing the same.
DK154607C (da) * 1978-12-21 1989-06-05 Sandoz Ag Fremgangsmaade til fremstilling af en laegemiddelform til oral administration af ergotalkaloider
DE2904310A1 (de) * 1979-02-05 1980-08-07 Boehringer Mannheim Gmbh Formlinge mit retardierter wirkstofffreisetzung und verfahren zu deren herstellung
JPS56115726A (en) * 1980-02-20 1981-09-11 Kaken Pharmaceut Co Ltd Pharmaceutical containing nifedipine
DE3033919A1 (de) * 1980-09-09 1982-04-22 Bayer Ag, 5090 Leverkusen Feste arzneizubereitungen enthaltend nifedipin und verfahren zu ihrer herstellung
US4442112A (en) * 1981-09-02 1984-04-10 Sandoz Ltd. Dihydropyridine derivatives useful in treating vascular headaches
EP0078430B2 (de) * 1981-10-29 1993-02-10 Bayer Ag Verfahren zur Herstellung von festen, schnellfreisetzenden Arzneizubereitungen mit Dihydropyridinen
CA1208558A (en) * 1982-10-07 1986-07-29 Kazuo Kigasawa Soft buccal
DE3318649A1 (de) * 1983-05-21 1984-11-22 Bayer Ag, 5090 Leverkusen Zweiphasenformulierung

Also Published As

Publication number Publication date
ES544075A0 (es) 1987-01-01
GB2196852B (en) 1989-05-17
GB2196851A (en) 1988-05-11
CA1264441A (en) 1990-01-16
SE8502950L (sv) 1985-12-15
DE3520184C2 (de) 1997-03-13
GB2160100B (en) 1989-06-01
SE504583C2 (sv) 1997-03-10
SE8502950D0 (sv) 1985-06-13
FR2565822B1 (fr) 1989-02-17
IT8548210A0 (it) 1985-06-13
AT391806B (de) 1990-12-10
GB2196851B (en) 1989-06-07
PT80635B (pt) 1987-10-20
AU4348685A (en) 1985-12-19
GB8727056D0 (en) 1987-12-23
AU587190B2 (en) 1989-08-10
CY1635A (en) 1992-11-06
GB2196852A (en) 1988-05-11
ES8702141A1 (es) 1987-01-01
BE902626A (fr) 1985-12-10
PT80635A (en) 1985-07-01
HK25192A (en) 1992-04-10
NZ212390A (en) 1992-02-25
FR2565822A1 (fr) 1985-12-20
IE851460L (en) 1985-12-14
NL8501578A (nl) 1986-01-02
HU198844B (en) 1989-12-28
AU4454389A (en) 1990-03-22
DK264785D0 (da) 1985-06-12
HUT40918A (en) 1987-03-30
IE58834B1 (en) 1993-11-17
GB2160100A (en) 1985-12-18
LU85946A1 (fr) 1986-01-24
NL194389C (nl) 2002-03-04
GR851430B (nl) 1985-11-25
DK264785A (da) 1985-12-15
GB8514855D0 (en) 1985-07-17
NL194389B (nl) 2001-11-01
GB8727055D0 (en) 1987-12-23
DE3520184A1 (de) 1985-12-19
IL75490A0 (en) 1985-10-31
IT1200080B (it) 1989-01-05
ATA174885A (de) 1990-06-15

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Date Code Title Description
B1 Patent granted (law 1993)
PUP Patent expired