DK167482A - Fremgangsmaade til fremstilling af produkter,der er anvendelige til behandling af melanomer - Google Patents

Fremgangsmaade til fremstilling af produkter,der er anvendelige til behandling af melanomer Download PDF

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Publication number
DK167482A
DK167482A DK167482A DK167482A DK167482A DK 167482 A DK167482 A DK 167482A DK 167482 A DK167482 A DK 167482A DK 167482 A DK167482 A DK 167482A DK 167482 A DK167482 A DK 167482A
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Denmark
Prior art keywords
melanomes
procedure
treatment
products used
manufacturing products
Prior art date
Application number
DK167482A
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English (en)
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DK159277C (da
DK159277B (da
Inventor
F K Jansen
P Gros
Original Assignee
Sanofi Sa
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Publication of DK167482A publication Critical patent/DK167482A/da
Publication of DK159277B publication Critical patent/DK159277B/da
Application granted granted Critical
Publication of DK159277C publication Critical patent/DK159277C/da

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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/395Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • A61K39/44Antibodies bound to carriers
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/18Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/30Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants from tumour cells
    • C07K16/3053Skin, nerves, brain
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/395Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A61K47/51Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
    • A61K47/68Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an antibody, an immunoglobulin or a fragment thereof, e.g. an Fc-fragment
    • A61K47/6801Drug-antibody or immunoglobulin conjugates defined by the pharmacologically or therapeutically active agent
    • A61K47/6803Drugs conjugated to an antibody or immunoglobulin, e.g. cisplatin-antibody conjugates
    • A61K47/6811Drugs conjugated to an antibody or immunoglobulin, e.g. cisplatin-antibody conjugates the drug being a protein or peptide, e.g. transferrin or bleomycin
    • A61K47/6817Toxins
    • A61K47/6819Plant toxins
    • A61K47/6825Ribosomal inhibitory proteins, i.e. RIP-I or RIP-II, e.g. Pap, gelonin or dianthin
    • A61K47/6827Ricin A
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A61K47/51Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
    • A61K47/68Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an antibody, an immunoglobulin or a fragment thereof, e.g. an Fc-fragment
    • A61K47/6835Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an antibody, an immunoglobulin or a fragment thereof, e.g. an Fc-fragment the modifying agent being an antibody or an immunoglobulin bearing at least one antigen-binding site
    • A61K47/6851Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an antibody, an immunoglobulin or a fragment thereof, e.g. an Fc-fragment the modifying agent being an antibody or an immunoglobulin bearing at least one antigen-binding site the antibody targeting a determinant of a tumour cell
    • A61K47/6865Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an antibody, an immunoglobulin or a fragment thereof, e.g. an Fc-fragment the modifying agent being an antibody or an immunoglobulin bearing at least one antigen-binding site the antibody targeting a determinant of a tumour cell the tumour determinant being from skin, nerves or brain cancer cell
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10STECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S530/00Chemistry: natural resins or derivatives; peptides or proteins; lignins or reaction products thereof
    • Y10S530/806Antigenic peptides or proteins
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10STECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S530/00Chemistry: natural resins or derivatives; peptides or proteins; lignins or reaction products thereof
    • Y10S530/827Proteins from mammals or birds
    • Y10S530/828Cancer

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medicinal Chemistry (AREA)
  • Immunology (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Cell Biology (AREA)
  • Organic Chemistry (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Toxicology (AREA)
  • Molecular Biology (AREA)
  • Microbiology (AREA)
  • Mycology (AREA)
  • Oncology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Neurosurgery (AREA)
  • Botany (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Peptides Or Proteins (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pyridine Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
DK167482A 1981-04-15 1982-04-14 Analogifremgangsmaade til fremstilling af produkter, der er anvendelige til behandling af melanomer DK159277C (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR8107596A FR2504010B1 (fr) 1981-04-15 1981-04-15 Medicaments anticancereux contenant la chaine a de la ricine associee a un anticorps antimelanome et procede pour leur preparation
FR8107596 1981-04-15

Publications (3)

Publication Number Publication Date
DK167482A true DK167482A (da) 1982-10-16
DK159277B DK159277B (da) 1990-09-24
DK159277C DK159277C (da) 1991-02-18

Family

ID=9257448

Family Applications (1)

Application Number Title Priority Date Filing Date
DK167482A DK159277C (da) 1981-04-15 1982-04-14 Analogifremgangsmaade til fremstilling af produkter, der er anvendelige til behandling af melanomer

Country Status (30)

Country Link
US (1) US4414148A (da)
EP (1) EP0063988B1 (da)
JP (1) JPS57179124A (da)
KR (1) KR880001045B1 (da)
AR (1) AR228394A1 (da)
AT (1) ATE17653T1 (da)
AU (1) AU556641B2 (da)
CA (1) CA1195248A (da)
CZ (1) CZ256482A3 (da)
DD (1) DD204849A5 (da)
DE (1) DE3268752D1 (da)
DK (1) DK159277C (da)
EG (1) EG15718A (da)
ES (1) ES511433A0 (da)
FI (1) FI76693C (da)
FR (1) FR2504010B1 (da)
GR (1) GR69199B (da)
HU (1) HU188314B (da)
IE (1) IE53009B1 (da)
IL (1) IL65441A0 (da)
MA (1) MA19429A1 (da)
NO (1) NO154905C (da)
NZ (1) NZ200302A (da)
OA (1) OA07069A (da)
PH (1) PH20846A (da)
PL (1) PL135800B1 (da)
PT (1) PT74741B (da)
SU (1) SU1329604A3 (da)
YU (1) YU83082A (da)
ZA (1) ZA822528B (da)

Families Citing this family (147)

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FR2504010B1 (fr) 1985-10-25
IL65441A0 (en) 1982-07-30
IE53009B1 (en) 1988-05-11
ES8303918A1 (es) 1983-02-16
NO154905C (no) 1987-01-14
ATE17653T1 (de) 1986-02-15
EG15718A (en) 1986-09-30
YU83082A (en) 1985-03-20
PL135800B1 (en) 1985-12-31
ZA822528B (en) 1983-02-23
PT74741A (fr) 1982-05-01
FI76693B (fi) 1988-08-31
GR69199B (da) 1982-05-06
NZ200302A (en) 1985-03-20
PH20846A (en) 1987-05-08
FI76693C (fi) 1988-12-12
NO821198L (no) 1982-10-18
PT74741B (fr) 1983-11-09
CA1195248A (en) 1985-10-15
CZ256482A3 (en) 1994-01-19
PL235981A1 (da) 1982-10-25
EP0063988A1 (fr) 1982-11-03
US4414148A (en) 1983-11-08
IE820815L (en) 1982-10-15
DD204849A5 (de) 1983-12-14
NO154905B (no) 1986-10-06
FI821304A0 (fi) 1982-04-14
KR880001045B1 (ko) 1988-06-18
DK159277C (da) 1991-02-18
MA19429A1 (fr) 1982-12-31
DK159277B (da) 1990-09-24
DE3268752D1 (en) 1986-03-13
OA07069A (fr) 1984-01-31
SU1329604A3 (ru) 1987-08-07
AU8251082A (en) 1983-04-21
KR830009777A (ko) 1983-12-23
FI821304L (fi) 1982-10-16
AR228394A1 (es) 1983-02-28
FR2504010A1 (fr) 1982-10-22
HU188314B (en) 1986-04-28
AU556641B2 (en) 1986-11-13
JPS57179124A (en) 1982-11-04
ES511433A0 (es) 1983-02-16
EP0063988B1 (fr) 1986-01-29

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