DK166582B1 - Pyridylmethoxyderivater og farmaceutisk acceptable salte og lethydrolyserbare estre deraf, deres fremstilling og farmaceutisk praeparat indeholdende samme - Google Patents
Pyridylmethoxyderivater og farmaceutisk acceptable salte og lethydrolyserbare estre deraf, deres fremstilling og farmaceutisk praeparat indeholdende samme Download PDFInfo
- Publication number
- DK166582B1 DK166582B1 DK096986A DK96986A DK166582B1 DK 166582 B1 DK166582 B1 DK 166582B1 DK 096986 A DK096986 A DK 096986A DK 96986 A DK96986 A DK 96986A DK 166582 B1 DK166582 B1 DK 166582B1
- Authority
- DK
- Denmark
- Prior art keywords
- pyridylmethoxy
- compound
- aniline
- quinolylmethoxy
- formula
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/24—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
- C07D213/28—Radicals substituted by singly-bound oxygen or sulphur atoms
- C07D213/30—Oxygen atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/24—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
- C07D213/28—Radicals substituted by singly-bound oxygen or sulphur atoms
- C07D213/32—Sulfur atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/24—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
- C07D213/28—Radicals substituted by singly-bound oxygen or sulphur atoms
- C07D213/32—Sulfur atoms
- C07D213/34—Sulfur atoms to which a second hetero atom is attached
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
- C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
- C07D215/12—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
- C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
- C07D215/12—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
- C07D215/14—Radicals substituted by oxygen atoms
Landscapes
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Engineering & Computer Science (AREA)
- Animal Behavior & Ethology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Pyridine Compounds (AREA)
- Quinoline Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (4)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB8506094 | 1985-03-08 | ||
| GB858506094A GB8506094D0 (en) | 1985-03-08 | 1985-03-08 | Chemical products |
| GB8525153 | 1985-10-11 | ||
| GB858525153A GB8525153D0 (en) | 1985-10-11 | 1985-10-11 | Chemical compounds |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| DK96986D0 DK96986D0 (da) | 1986-03-04 |
| DK96986A DK96986A (da) | 1986-09-09 |
| DK166582B1 true DK166582B1 (da) | 1993-06-14 |
Family
ID=26288945
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK096986A DK166582B1 (da) | 1985-03-08 | 1986-03-04 | Pyridylmethoxyderivater og farmaceutisk acceptable salte og lethydrolyserbare estre deraf, deres fremstilling og farmaceutisk praeparat indeholdende samme |
Country Status (18)
| Country | Link |
|---|---|
| US (2) | US4826987A (es) |
| JP (1) | JPH0764813B2 (es) |
| AU (1) | AU585586B2 (es) |
| BE (1) | BE904368A (es) |
| CA (1) | CA1276640C (es) |
| DE (1) | DE3607382A1 (es) |
| DK (1) | DK166582B1 (es) |
| ES (1) | ES8802610A1 (es) |
| FR (1) | FR2578540B1 (es) |
| GB (1) | GB2173788B (es) |
| GR (1) | GR860628B (es) |
| IE (1) | IE58870B1 (es) |
| IT (1) | IT1221079B (es) |
| LU (1) | LU86349A1 (es) |
| NL (1) | NL8600596A (es) |
| NZ (1) | NZ215347A (es) |
| PT (1) | PT82147B (es) |
| SE (1) | SE463819B (es) |
Families Citing this family (24)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ATE68789T1 (de) * | 1985-10-16 | 1991-11-15 | Merck Frosst Canada Inc | 2-substituierte chinoline. |
| DK196688A (da) * | 1987-04-28 | 1988-10-29 | Fujisawa Pharmaceutical Co | Bicykliske forbindelser og fremgangsmaade til fremstilling deraf |
| US4826990A (en) * | 1987-09-30 | 1989-05-02 | American Home Products Corporation | 2-aryl substituted heterocyclic compounds as antiallergic and antiinflammatory agents |
| GB8728051D0 (en) * | 1987-12-01 | 1988-01-06 | Leo Pharm Prod Ltd | Chemical compounds |
| US4889935A (en) * | 1987-12-18 | 1989-12-26 | American Home Products Corporation | Aminoguanidine derivatives |
| US5248685A (en) * | 1989-04-07 | 1993-09-28 | Pfizer Inc. | Substituted 1-[3-(heteroarylmethoxy)phenyl]alkanols and related compounds in the treatment of asthma |
| DE3927369A1 (de) * | 1989-08-19 | 1991-02-21 | Bayer Ag | Substituierte n-(chinolin-2-yl-methoxy)benzyl-sulfonyl-harnstoffe |
| DE3935139A1 (de) * | 1989-10-21 | 1991-04-25 | Bayer Ag | Substituierte (chinolin-2-yl-methoxy)phenyl-thioharnstoffe |
| US5021576A (en) * | 1989-10-27 | 1991-06-04 | American Home Products Corporation | 2-Anilino phenylacetic acid derivatives |
| US5324747A (en) * | 1992-07-15 | 1994-06-28 | Hoffmann-La Roche Inc. | N-substituted anilines, inhibitors of phospholipases A2 |
| US5840318A (en) * | 1993-05-11 | 1998-11-24 | Immunom Technologies, Inc. | Methods and compositions for modulating immune systems of animals |
| US7189834B2 (en) * | 1993-05-11 | 2007-03-13 | Marshall William E | Oligoribonucleotides alert the immune system of animals to the imminence of microbial infection |
| US5508408A (en) * | 1993-09-10 | 1996-04-16 | Ciba-Geigy Corporation | Quinoline compound |
| US5795900A (en) * | 1995-10-03 | 1998-08-18 | Abbott Laboratories | Symmetrical bis-heteroaryl-methoxy-phenylalkyl carboxylates as inhibitors of leukotriene biosynthesis |
| US5668150A (en) * | 1996-07-26 | 1997-09-16 | Abbott Laboratories | Non-symmetrical bis-heteroarylmethoxyphenylalkyl carboxylates as inhibitors of leukotriene biosynthesis |
| WO1999033846A2 (en) * | 1997-12-31 | 1999-07-08 | The University Of Kansas | Water soluble prodrugs of secondary and tertiary amine containing drugs and methods of making thereof |
| HN2001000008A (es) * | 2000-01-21 | 2003-12-11 | Inc Agouron Pharmaceuticals | Compuesto de amida y composiciones farmaceuticas para inhibir proteinquinasas, y su modo de empleo |
| US7977359B2 (en) * | 2005-11-04 | 2011-07-12 | Amira Pharmaceuticals, Inc. | 5-lipdxygenase-activating protein (FLAP) inhibitors |
| US8399666B2 (en) * | 2005-11-04 | 2013-03-19 | Panmira Pharmaceuticals, Llc | 5-lipoxygenase-activating protein (FLAP) inhibitors |
| GB2431927B (en) * | 2005-11-04 | 2010-03-17 | Amira Pharmaceuticals Inc | 5-Lipoxygenase-activating protein (FLAP) inhibitors |
| TW200920369A (en) * | 2007-10-26 | 2009-05-16 | Amira Pharmaceuticals Inc | 5-lipoxygenase activating protein (flap) inhibitor |
| BRPI0912267A2 (pt) * | 2008-05-23 | 2015-10-13 | Amira Pharmaceuticals Inc | sal farmaceuticamente aceitável, composição farmacêutica, artigo de fabricação, métodos para tratar asma, rinite alérgica, doença, lesões gástricas e dor, métodos para prevenir broncoconstrição e rinite alérgica, uso de um sal farmaceuticamente aceitável, e, processo para a preparação de um sal farmaceuticamente aceitável. |
| US8546431B2 (en) | 2008-10-01 | 2013-10-01 | Panmira Pharmaceuticals, Llc | 5-lipoxygenase-activating protein (FLAP) inhibitors |
| TW201215607A (en) | 2010-07-02 | 2012-04-16 | Lundbeck & Co As H | Aryl-and heteroarylamid derivatives as PDE10A enzyme inhibitor |
Family Cites Families (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US31624A (en) * | 1861-03-05 | Tatting-frame | ||
| US2761865A (en) * | 1954-07-07 | 1956-09-04 | Hoffmann La Roche | Pyridylalkyl sulfones |
| US4003906A (en) * | 1974-01-22 | 1977-01-18 | The Dow Chemical Company | Substituted pyridinyl methylthio or (methylsulfonyl)benzeneamines |
| GB2069492B (en) * | 1980-02-20 | 1984-02-29 | Wyeth John & Brother Ltd | Sulphur compounds |
| GB2069493B (en) * | 1980-02-20 | 1984-02-29 | Wyeth John & Brother Ltd | Pyridine derivatives |
| US4567184A (en) * | 1982-12-01 | 1986-01-28 | Usv Pharmaceutical Corporation | Certain aryl or hetero-aryl derivatives of 1-hydroxy-pentane or 1-hydroxy-hexane which are useful for treating inflammation and allergies |
| IE56702B1 (en) * | 1982-12-01 | 1991-11-06 | Usv Pharma Corp | Antiinflammatory antiallergic compounds |
| JPS5988835U (ja) * | 1982-12-06 | 1984-06-15 | ホシデン株式会社 | スイツチ |
| US4486593A (en) * | 1983-01-19 | 1984-12-04 | The Upjohn Company | 2-,3-, or 4-Pyridinylmethylamino arylic acids as thromboxane A2 synthetase and 5-lipoxygenase inhibitors |
| US4563463A (en) * | 1983-03-18 | 1986-01-07 | Usv Pharmaceutical Corp. | 2-Oxo-1,3-oxazolo[4,5-h] quinolines useful as anti-allergy agents |
| US4554355A (en) * | 1984-07-19 | 1985-11-19 | American Home Products Corporation | Heterocyclic compounds as antiallergic agents |
| US5109009A (en) * | 1985-03-08 | 1992-04-28 | Leo Pharmaceutical Products Ltd. | Quinoline and pyridine compounds and inhibition of 5-lipoxygenases therewith |
-
1986
- 1986-02-10 IE IE37086A patent/IE58870B1/en not_active IP Right Cessation
- 1986-02-20 GB GB08604183A patent/GB2173788B/en not_active Expired
- 1986-02-28 US US06/834,542 patent/US4826987A/en not_active Expired - Fee Related
- 1986-02-28 SE SE8600913A patent/SE463819B/sv not_active IP Right Cessation
- 1986-03-03 NZ NZ215347A patent/NZ215347A/xx unknown
- 1986-03-04 DK DK096986A patent/DK166582B1/da not_active IP Right Cessation
- 1986-03-06 GR GR860628A patent/GR860628B/el unknown
- 1986-03-06 IT IT67183/86A patent/IT1221079B/it active
- 1986-03-06 CA CA000503464A patent/CA1276640C/en not_active Expired - Fee Related
- 1986-03-06 PT PT82147A patent/PT82147B/pt not_active IP Right Cessation
- 1986-03-06 DE DE19863607382 patent/DE3607382A1/de not_active Ceased
- 1986-03-07 FR FR868603268A patent/FR2578540B1/fr not_active Expired - Fee Related
- 1986-03-07 ES ES552805A patent/ES8802610A1/es not_active Expired
- 1986-03-07 AU AU54444/86A patent/AU585586B2/en not_active Ceased
- 1986-03-07 LU LU86349A patent/LU86349A1/fr unknown
- 1986-03-07 BE BE0/216378A patent/BE904368A/fr not_active IP Right Cessation
- 1986-03-07 NL NL8600596A patent/NL8600596A/nl not_active Application Discontinuation
- 1986-03-08 JP JP61051286A patent/JPH0764813B2/ja not_active Expired - Lifetime
-
1990
- 1990-12-31 US US07/633,390 patent/US5157039A/en not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| AU585586B2 (en) | 1989-06-22 |
| GR860628B (en) | 1986-06-26 |
| ES8802610A1 (es) | 1988-09-16 |
| IE58870B1 (en) | 1993-11-17 |
| DE3607382A1 (de) | 1986-09-11 |
| PT82147A (en) | 1986-04-01 |
| US5157039A (en) | 1992-10-20 |
| DK96986D0 (da) | 1986-03-04 |
| SE463819B (sv) | 1991-01-28 |
| NL8600596A (nl) | 1986-10-01 |
| PT82147B (pt) | 1988-07-29 |
| AU5444486A (en) | 1986-09-18 |
| SE8600913D0 (sv) | 1986-02-28 |
| US4826987A (en) | 1989-05-02 |
| JPS61207374A (ja) | 1986-09-13 |
| FR2578540B1 (fr) | 1990-11-16 |
| GB8604183D0 (en) | 1986-03-26 |
| DK96986A (da) | 1986-09-09 |
| JPH0764813B2 (ja) | 1995-07-12 |
| CA1276640C (en) | 1990-11-20 |
| GB2173788A (en) | 1986-10-22 |
| NZ215347A (en) | 1990-02-26 |
| IE860370L (en) | 1986-09-08 |
| IT1221079B (it) | 1990-06-21 |
| ES552805A0 (es) | 1988-09-16 |
| LU86349A1 (fr) | 1987-04-02 |
| IT8667183A0 (it) | 1986-03-06 |
| FR2578540A1 (fr) | 1986-09-12 |
| GB2173788B (en) | 1988-08-10 |
| SE8600913L (sv) | 1986-09-09 |
| BE904368A (fr) | 1986-09-08 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| B1 | Patent granted (law 1993) | ||
| PBP | Patent lapsed |