DK166386C - Diastereoisomer a af 2,6-dimethyl-4-(3-nitrophenyl)-1,4-dihydropyridin-3,5-dicarboxylsyre-3-(1-benzylpyrrolidin-3-yl)ester-5-methylester, den hoejredrejende optiske isomer heraf, fremgangsmaader til fremstilling af forbindelserne og farmaceutiske praeparater indeholdende disse - Google Patents
Diastereoisomer a af 2,6-dimethyl-4-(3-nitrophenyl)-1,4-dihydropyridin-3,5-dicarboxylsyre-3-(1-benzylpyrrolidin-3-yl)ester-5-methylester, den hoejredrejende optiske isomer heraf, fremgangsmaader til fremstilling af forbindelserne og farmaceutiske praeparater indeholdende disseInfo
- Publication number
- DK166386C DK166386C DK169185A DK169185A DK166386C DK 166386 C DK166386 C DK 166386C DK 169185 A DK169185 A DK 169185A DK 169185 A DK169185 A DK 169185A DK 166386 C DK166386 C DK 166386C
- Authority
- DK
- Denmark
- Prior art keywords
- diastereoisomer
- compounds
- ester
- benzylpyrrolidin
- dihydropyridine
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D207/18—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member
- C07D207/22—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D207/24—Oxygen or sulfur atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
- C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D211/80—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members
- C07D211/84—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen directly attached to ring carbon atoms
- C07D211/90—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Hydrogenated Pyridines (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (6)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP7599884A JPS60231673A (ja) | 1984-04-16 | 1984-04-16 | Ｙｍ−０９７３０のジアステレオマーａまたはその酸付加塩、該化合物の製造方法および該化合物からなる医薬 |
| JP7599884 | 1984-04-16 | ||
| JP59114098A JPS60258179A (ja) | 1984-06-04 | 1984-06-04 | Ｙｍ−０９７３０のジアステレオマ−ａの右旋性光学異性体またはその酸付加塩，該化合物の製造方法および該化合物からなる医薬 |
| JP11409884 | 1984-06-04 | ||
| JP59165793A JPS6143187A (ja) | 1984-08-07 | 1984-08-07 | Ｙｍ−０９７３０のジアステレオマ−ａの右旋性光学異性体の新規製法 |
| JP16579384 | 1984-08-07 |
Publications (4)
| Publication Number | Publication Date |
|---|---|
| DK169185D0 DK169185D0 (da) | 1985-04-15 |
| DK169185A DK169185A (da) | 1985-10-17 |
| DK166386B DK166386B (da) | 1993-05-10 |
| DK166386C true DK166386C (da) | 1993-09-27 |
Family
ID=27302015
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK169185A DK166386C (da) | 1984-04-16 | 1985-04-15 | Diastereoisomer a af 2,6-dimethyl-4-(3-nitrophenyl)-1,4-dihydropyridin-3,5-dicarboxylsyre-3-(1-benzylpyrrolidin-3-yl)ester-5-methylester, den hoejredrejende optiske isomer heraf, fremgangsmaader til fremstilling af forbindelserne og farmaceutiske praeparater indeholdende disse |
Country Status (13)
| Country | Link |
|---|---|
| EP (1) | EP0160451B1 (de) |
| KR (1) | KR920003626B1 (de) |
| AT (1) | ATE66677T1 (de) |
| AU (1) | AU569618B2 (de) |
| CA (2) | CA1273930A (de) |
| DE (1) | DE3583882D1 (de) |
| DK (1) | DK166386C (de) |
| ES (4) | ES8608512A1 (de) |
| GR (1) | GR850872B (de) |
| IE (1) | IE57811B1 (de) |
| MX (1) | MX7363E (de) |
| NL (1) | NL990023I2 (de) |
| NO (1) | NO159594C (de) |
Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB9405833D0 (en) * | 1994-03-24 | 1994-05-11 | Pfizer Ltd | Separation of the enantiomers of amlodipine |
| DE4443168A1 (de) * | 1994-12-05 | 1996-06-13 | Bayer Ag | Neues hochselektives Verfahren zur Herstellung von enantiomerenreinen phenylsubstituierten 1,4-Dihydropyridin-3,5-dicarbonsäurederivaten |
| KR100939347B1 (ko) | 2005-07-20 | 2010-01-29 | (주)카이로드 | 광학적으로 순수한 (ｓ)-3-히드록시 피롤리딘의 제조방법 |
| ITMI20120513A1 (it) | 2012-03-29 | 2013-09-30 | Lusochimica Spa | Nuove forme polimorfe della barnidipina cloridrato e processi per la loro preparazione |
| EP4382529A1 (de) | 2022-12-07 | 2024-06-12 | Bayer Consumer Care AG | Verfahren zur herstellung von reinem (3s)-pyrrolidin-3-ol und reinem (3s)-pyrrolidin-3-ol-hydrochlorid |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS55301A (en) * | 1978-02-14 | 1980-01-05 | Yamanouchi Pharmaceut Co Ltd | 1,4-dihydropyridine-3,5-dicarboxylic ester derivative and its preparation |
-
1985
- 1985-04-08 GR GR850872A patent/GR850872B/el not_active IP Right Cessation
- 1985-04-13 KR KR1019850002490A patent/KR920003626B1/ko not_active IP Right Cessation
- 1985-04-15 DK DK169185A patent/DK166386C/da not_active IP Right Cessation
- 1985-04-15 ES ES542253A patent/ES8608512A1/es not_active Expired
- 1985-04-15 NO NO851494A patent/NO159594C/no not_active IP Right Cessation
- 1985-04-16 AT AT85302666T patent/ATE66677T1/de not_active IP Right Cessation
- 1985-04-16 EP EP85302666A patent/EP0160451B1/de not_active Expired - Lifetime
- 1985-04-16 CA CA000479294A patent/CA1273930A/en not_active Expired - Lifetime
- 1985-04-16 MX MX8511525U patent/MX7363E/es unknown
- 1985-04-16 AU AU41318/85A patent/AU569618B2/en not_active Expired
- 1985-04-16 IE IE985/85A patent/IE57811B1/en not_active IP Right Cessation
- 1985-04-16 DE DE85302666T patent/DE3583882D1/de not_active Expired - Lifetime
-
1986
- 1986-02-07 ES ES551767A patent/ES8704937A1/es not_active Expired
- 1986-02-07 ES ES551769A patent/ES8704866A1/es not_active Expired
- 1986-02-07 ES ES551768A patent/ES8707522A1/es not_active Expired
-
1990
- 1990-05-25 CA CA000615749A patent/CA1289565C/en not_active Expired - Lifetime
-
1999
- 1999-07-30 NL NL990023C patent/NL990023I2/nl unknown
Also Published As
| Publication number | Publication date |
|---|---|
| ES551768A0 (es) | 1987-08-01 |
| EP0160451A3 (en) | 1987-07-08 |
| AU569618B2 (en) | 1988-02-11 |
| ATE66677T1 (de) | 1991-09-15 |
| AU4131885A (en) | 1985-10-24 |
| NL990023I2 (nl) | 1999-12-01 |
| KR920003626B1 (ko) | 1992-05-04 |
| CA1273930A (en) | 1990-09-11 |
| ES8704937A1 (es) | 1987-04-16 |
| EP0160451B1 (de) | 1991-08-28 |
| NO851494L (no) | 1985-10-17 |
| ES8704866A1 (es) | 1987-04-16 |
| CA1289565C (en) | 1991-09-24 |
| EP0160451A2 (de) | 1985-11-06 |
| IE57811B1 (en) | 1993-04-21 |
| ES8707522A1 (es) | 1987-08-01 |
| NO159594C (no) | 1989-01-18 |
| MX7363E (es) | 1988-08-04 |
| DE3583882D1 (de) | 1991-10-02 |
| DK166386B (da) | 1993-05-10 |
| NO159594B (no) | 1988-10-10 |
| ES542253A0 (es) | 1986-07-01 |
| ES551767A0 (es) | 1987-04-16 |
| KR860008162A (ko) | 1986-11-12 |
| ES551769A0 (es) | 1987-04-16 |
| DK169185D0 (da) | 1985-04-15 |
| GR850872B (de) | 1985-11-25 |
| ES8608512A1 (es) | 1986-07-01 |
| IE850985L (en) | 1985-10-25 |
| NL990023I1 (nl) | 1999-10-01 |
| DK169185A (da) | 1985-10-17 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| B1 | Patent granted (law 1993) | ||
| PUP | Patent expired |