DK165954C - 2,3-dihydrobenzofuran-5-sulfonamidderivater samt antihypertensive og diuretiske midler indeholdende disse - Google Patents

2,3-dihydrobenzofuran-5-sulfonamidderivater samt antihypertensive og diuretiske midler indeholdende disse

Info

Publication number
DK165954C
DK165954C DK403185A DK403185A DK165954C DK 165954 C DK165954 C DK 165954C DK 403185 A DK403185 A DK 403185A DK 403185 A DK403185 A DK 403185A DK 165954 C DK165954 C DK 165954C
Authority
DK
Denmark
Prior art keywords
dihydrobenzofuran
antihypertensive
agents containing
diuretic agents
sulphonamide derivatives
Prior art date
Application number
DK403185A
Other languages
English (en)
Other versions
DK165954B (da
DK403185A (da
DK403185D0 (da
Inventor
Hiroshi Harada
Yoshihiro Matsushita
Masuhisa Nakamura
Yukio Yonetani
Original Assignee
Shionogi & Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Shionogi & Co filed Critical Shionogi & Co
Publication of DK403185D0 publication Critical patent/DK403185D0/da
Publication of DK403185A publication Critical patent/DK403185A/da
Publication of DK165954B publication Critical patent/DK165954B/da
Application granted granted Critical
Publication of DK165954C publication Critical patent/DK165954C/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/77—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D307/78—Benzo [b] furans; Hydrogenated benzo [b] furans
    • C07D307/79—Benzo [b] furans; Hydrogenated benzo [b] furans with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to carbon atoms of the hetero ring
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/10—Antioedematous agents; Diuretics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/77—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D307/78—Benzo [b] furans; Hydrogenated benzo [b] furans
    • C07D307/79—Benzo [b] furans; Hydrogenated benzo [b] furans with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to carbon atoms of the hetero ring
    • C07D307/80—Radicals substituted by oxygen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/77—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D307/78—Benzo [b] furans; Hydrogenated benzo [b] furans
    • C07D307/82—Benzo [b] furans; Hydrogenated benzo [b] furans with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to carbon atoms of the hetero ring
    • C07D307/84—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
    • C07D307/85—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen attached in position 2
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/77—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D307/87—Benzo [c] furans; Hydrogenated benzo [c] furans
    • C07D307/88—Benzo [c] furans; Hydrogenated benzo [c] furans with one oxygen atom directly attached in position 1 or 3

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Hematology (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Diabetes (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Furan Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
DK403185A 1984-09-05 1985-09-04 2,3-dihydrobenzofuran-5-sulfonamidderivater samt antihypertensive og diuretiske midler indeholdende disse DK165954C (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP18697184 1984-09-05
JP59186971A JPS6163671A (ja) 1984-09-05 1984-09-05 ２，３−ジヒドロベンゾフラン−５−スルホンアミド誘導体および降圧利尿剤

Publications (4)

Publication Number Publication Date
DK403185D0 DK403185D0 (da) 1985-09-04
DK403185A DK403185A (da) 1986-03-06
DK165954B DK165954B (da) 1993-02-15
DK165954C true DK165954C (da) 1993-07-05

Family

ID=16197928

Family Applications (1)

Application Number Title Priority Date Filing Date
DK403185A DK165954C (da) 1984-09-05 1985-09-04 2,3-dihydrobenzofuran-5-sulfonamidderivater samt antihypertensive og diuretiske midler indeholdende disse

Country Status (15)

Country Link
US (1) US4659709A (da)
EP (1) EP0173899B1 (da)
JP (1) JPS6163671A (da)
KR (1) KR930002100B1 (da)
AT (1) ATE70534T1 (da)
AU (1) AU592060B2 (da)
CA (1) CA1265800A (da)
DE (1) DE3584919D1 (da)
DK (1) DK165954C (da)
GB (1) GB2164039B (da)
IE (1) IE58911B1 (da)
NO (1) NO169487C (da)
NZ (1) NZ213197A (da)
PT (1) PT81033B (da)
ZA (1) ZA856277B (da)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5116874A (en) * 1985-09-23 1992-05-26 Eli Lilly And Company Anti-tumor method and compounds
JPH01100164A (ja) * 1987-10-12 1989-04-18 Shionogi & Co Ltd スルファモイル−２−ベンゾフランカルボン酸誘導体
DE3861963D1 (de) * 1987-12-24 1991-04-11 Boehringer Mannheim Gmbh Heterocyclisch substituierte alkylsulfonamide, verfahren zu ihrer herstellung sowie arzneimittel.
GB9110636D0 (en) * 1991-05-16 1991-07-03 Glaxo Group Ltd Chemical compounds
US5254582A (en) * 1992-02-05 1993-10-19 Eli Lilly And Company Antitumor compositions and methods
US5387681A (en) * 1992-08-19 1995-02-07 Eli Lilly And Company Synthesis of bicyclic aromatic sulfonic acids sulfonyl chlorides and sulfonamides
US6150402A (en) * 1994-08-15 2000-11-21 Loma Linda University Medical Center Natriuretic compounds
DE10135499A1 (de) * 2001-07-20 2003-01-30 Merck Patent Gmbh Indanverbindungen mit negativem Delta-epsilon
US7795242B2 (en) * 2003-10-15 2010-09-14 The Brigham And Women's Hospital, Inc. Methods and compositions for immunomodulation
EP1805158B1 (en) 2004-10-29 2018-06-27 Kalypsys, Inc. Sulfonyl-substituted bicyclic compounds as modulators of ppar
WO2007051095A1 (en) 2005-10-25 2007-05-03 Kalypsys, Inc. Salts of modulators of ppar and methods of treating metabolic disorders
US20080176861A1 (en) 2007-01-23 2008-07-24 Kalypsys, Inc. Sulfonyl-substituted bicyclic compounds as ppar modulators for the treatment of non-alcoholic steatohepatitis

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU6004073A (en) * 1972-09-09 1975-03-06 Basf Ag Fluorescent benzofuran compounds
US4401669A (en) * 1978-01-27 1983-08-30 Merck & Co., Inc. 2,3-Dihydro-substituted-5-benzoyl benzofuran-2-carboxylic acids and their use in treating hypertension
CA1145758A (en) * 1979-05-16 1983-05-03 Shell Canada Limited 2,3-dihydro-2-benzofurancarboxamide derivatives
US4237130A (en) * 1979-06-21 1980-12-02 Merck & Co., Inc. 2,3-Dihydro-6,7-disubstituted-5-(substituted sulfonyl)benzofuran-2-carboxylic acids
DE3317884A1 (de) * 1983-05-17 1984-11-22 Hoechst Ag, 6230 Frankfurt 5-(4-chlor-3-sulfamoylbenzoyl)-2,3-dihydro-2-benzofurancarbonsaeuren und verfahren zu ihrer herstellung
US4544667A (en) * 1984-02-09 1985-10-01 Merck & Co., Inc. 2-Sulfamoylbenzo[b]furan derivatives for the treatment of elevated intraocular pressure

Also Published As

Publication number Publication date
NO169487B (no) 1992-03-23
PT81033A (en) 1985-09-01
GB8521967D0 (en) 1985-10-09
US4659709A (en) 1987-04-21
AU592060B2 (en) 1990-01-04
ZA856277B (en) 1986-04-30
JPH0354945B2 (da) 1991-08-21
IE58911B1 (en) 1993-12-01
AU4621585A (en) 1986-03-13
DK165954B (da) 1993-02-15
EP0173899A3 (en) 1988-07-20
GB2164039B (en) 1988-05-18
EP0173899B1 (en) 1991-12-18
NZ213197A (en) 1989-01-06
NO853441L (no) 1986-03-06
DK403185A (da) 1986-03-06
PT81033B (pt) 1987-09-18
KR930002100B1 (ko) 1993-03-26
CA1265800A (en) 1990-02-13
EP0173899A2 (en) 1986-03-12
DK403185D0 (da) 1985-09-04
NO169487C (no) 1992-07-01
GB2164039A (en) 1986-03-12
JPS6163671A (ja) 1986-04-01
KR860002490A (ko) 1986-04-26
IE852188L (en) 1986-03-05
DE3584919D1 (de) 1992-01-30
ATE70534T1 (de) 1992-01-15

Similar Documents

Publication Publication Date Title
DK165954C (da) 2,3-dihydrobenzofuran-5-sulfonamidderivater samt antihypertensive og diuretiske midler indeholdende disse
YU47204B (sh) Derivati didehidro-vitamina d3
ATE81858T1 (de) 6-thioxanthinderivate.
SE9002500D0 (sv) Farmaceutisk, nac-innehaallande komposition foer oral administrering
DE69831576T2 (de) Chromium/biotin behandlung von typ-ii diabetes
ES2062236T3 (es) Emulsion de agua en aceite.
NO854189L (no) Fremgangsmaate for skrivende registrering av soner i homogen grunn langs siden av en broennboring.
Hathaway Subclinical effects of trinitrotoluene: A review of epidemiology studies.
NZ334949A (en) Stabilised pharmaceutical composition of quinupristine and dalfopristine with methanesulphonic acid or hydrochloric acid
MY100938A (en) Arylkylimidazole derivatives.
ES2001940A6 (es) Procedimiento para producir un preparado farmaceutico a base de un inhibidor de la enzima convertidora de angiotensina y un diuretico de asa
ES2018387A6 (es) Procedimiento de obtencion de un medicamento para inhibir la infeccion de celulas por virus hiv.
MY100078A (en) Improvements relating to the expansion of tobacco.
SE8202351L (sv) Farmaceutiskt preparat
IT1224250B (it) Associzione del depiprazolo con la morfina
DE3785953D1 (de) Bakterientoetende gemische.
Gainer Catholic missionaries as agent of social change among the Metis and Indians of Red River: 1818-1845.
Robb Hellenic Plans Public Stock Offer for Greek--Soviet Alumina Project
Hilsdorf Japan Leads in Developing Advanced Ceramics
DE3779420D1 (de) In "einfuegungs-art" benutzbares kopiergeraet.
JO1378B1 (en) Innovative galenic forms of sulfides that can be taken orally
IT8553332V0 (it) Canaline contro lo stillicidio del le acque in galleria
JO1451B1 (en) Stopping the development (growth) of diseases
SE8406353D0 (sv) Forfarande och anordning for sortering av han- och honfisk
SU1297428A1 (ru) 54, 56:58, 60-дииндий (iii) дихлор-6, 11:19, 24:32, 37:45, 50-тетраимино-5-, 52:13, 18:20, 31:39, 44-тетранитрилоктабензо [с, д, е, р, и, у, d, h] (1, 10, 19, 28) - тетраазациклогексатриаконтин как полупроводник

Legal Events

Date Code Title Description
PBP Patent lapsed