ATE35414T1 - Salze von dimeren indol-dihydroindol-alkaloiden. - Google Patents

Salze von dimeren indol-dihydroindol-alkaloiden.

Info

Publication number
ATE35414T1
ATE35414T1 AT84308817T AT84308817T ATE35414T1 AT E35414 T1 ATE35414 T1 AT E35414T1 AT 84308817 T AT84308817 T AT 84308817T AT 84308817 T AT84308817 T AT 84308817T AT E35414 T1 ATE35414 T1 AT E35414T1
Authority
AT
Austria
Prior art keywords
salts
dimeric indole
alkaloids
dihydroindole alkaloids
indole dihydroindole
Prior art date
Application number
AT84308817T
Other languages
English (en)
Inventor
Stanislaw Rolski
Ralph Robert Pfeiffer
Original Assignee
Lilly Co Eli
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Lilly Co Eli filed Critical Lilly Co Eli
Application granted granted Critical
Publication of ATE35414T1 publication Critical patent/ATE35414T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C309/00—Sulfonic acids; Halides, esters, or anhydrides thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D519/00—Heterocyclic compounds containing more than one system of two or more relevant hetero rings condensed among themselves or condensed with a common carbocyclic ring system not provided for in groups C07D453/00 or C07D455/00
    • C07D519/04—Dimeric indole alkaloids, e.g. vincaleucoblastine

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Indole Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
AT84308817T 1983-12-21 1984-12-17 Salze von dimeren indol-dihydroindol-alkaloiden. ATE35414T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US06/564,119 US4558053A (en) 1983-12-21 1983-12-21 Naphthalene-1,5-disulfonate salts of dimeric indole-dihydroindole alkaloids
EP84308817A EP0147152B1 (de) 1983-12-21 1984-12-17 Salze von dimeren Indol-dihydroindol-Alkaloiden

Publications (1)

Publication Number Publication Date
ATE35414T1 true ATE35414T1 (de) 1988-07-15

Family

ID=24253222

Family Applications (1)

Application Number Title Priority Date Filing Date
AT84308817T ATE35414T1 (de) 1983-12-21 1984-12-17 Salze von dimeren indol-dihydroindol-alkaloiden.

Country Status (6)

Country Link
US (1) US4558053A (de)
EP (1) EP0147152B1 (de)
JP (1) JPS60169488A (de)
AT (1) ATE35414T1 (de)
DE (1) DE3472405D1 (de)
GB (1) GB2151621B (de)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5095109A (en) * 1989-06-08 1992-03-10 University Of Vermont Novel alkaloids
FR2918566B1 (fr) 2007-07-11 2009-10-09 Pierre Fabre Medicament Sa Composition pharmaceutique stable d'un sel hydrosoluble de vinflunine.
US20130178618A1 (en) 2012-01-10 2013-07-11 William Allen Boulanger Novel pharmaceutical intermediates and methods for preparing the same
US12116372B1 (en) 2023-12-14 2024-10-15 William Allen Boulanger Process for preparing methyl 3-bromo-2-(2,3,4,9-tetrahydro-1H-pyrido[3,4-b]indol-1-yl)propanoate

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US30560A (en) * 1860-11-06 Improvement in lightning-rods
US3097137A (en) * 1960-05-19 1963-07-09 Canadian Patents Dev Vincaleukoblastine
US3205220A (en) * 1961-10-26 1965-09-07 Lilly Co Eli Leurosidine and leurocristine and their production
US4012390A (en) * 1974-10-16 1977-03-15 Eli Lilly And Company Vinblastinoic acid
USRE30560E (en) 1976-12-06 1981-03-31 Eli Lilly And Company Oxazolidinedione derivatives of Vinca alkaloids
US4143041A (en) * 1977-01-19 1979-03-06 Eli Lilly And Company 4'-Deoxyvincristine and related compounds
US4191688A (en) * 1977-08-08 1980-03-04 Eli Lilly And Company Amides of leurosine, leuroformine, desacetylleurosine and desacetylleuroformine
US4203898A (en) * 1977-08-29 1980-05-20 Eli Lilly And Company Amide derivatives of VLB, leurosidine, leurocristine and related dimeric alkaloids
US4259242A (en) * 1978-10-10 1981-03-31 Eli Lilly And Company Method of preparing vindesine sulfate
AR225153A1 (es) * 1978-10-10 1982-02-26 Lilly Co Eli Un procedimiento para la preparacion de sulfato de vindesina

Also Published As

Publication number Publication date
GB2151621B (en) 1987-07-08
US4558053A (en) 1985-12-10
DE3472405D1 (en) 1988-08-04
EP0147152A3 (en) 1985-08-14
GB8431804D0 (en) 1985-01-30
GB2151621A (en) 1985-07-24
EP0147152A2 (de) 1985-07-03
EP0147152B1 (de) 1988-06-29
JPS60169488A (ja) 1985-09-02

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Legal Events

Date Code Title Description
UEP Publication of translation of european patent specification
REN Ceased due to non-payment of the annual fee