ES2007265A6 - Un metodo para preparar conjugados de indol-portador biologicamente activos. - Google Patents

Un metodo para preparar conjugados de indol-portador biologicamente activos.

Info

Publication number
ES2007265A6
ES2007265A6 ES8802228A ES8802228A ES2007265A6 ES 2007265 A6 ES2007265 A6 ES 2007265A6 ES 8802228 A ES8802228 A ES 8802228A ES 8802228 A ES8802228 A ES 8802228A ES 2007265 A6 ES2007265 A6 ES 2007265A6
Authority
ES
Spain
Prior art keywords
biologically active
indol
carrier conjugates
preparing biologically
preparing
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES8802228A
Other languages
English (en)
Inventor
Jan Marcusen
Peter Bjarne Ulvskov
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Danske Sukkerfabrikker AS
Original Assignee
Danske Sukkerfabrikker AS
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Danske Sukkerfabrikker AS filed Critical Danske Sukkerfabrikker AS
Publication of ES2007265A6 publication Critical patent/ES2007265A6/es
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
    • C07D403/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/04—Indoles; Hydrogenated indoles
    • C07D209/10—Indoles; Hydrogenated indoles with substituted hydrocarbon radicals attached to carbon atoms of the hetero ring
    • C07D209/18—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Indole Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)

Abstract

UN METODO PARA PREPARAR CONJUGADOS DE INDOL-PORTADOR BIOLOGICAMENTE ACTIVOS, QUE COMPRENDE COPULAR COVALENTEMENTE, EN UN SISTEMA DISOLVENTE, UN PORTADOR Y UN COMPUESTO DE INDOL QUE ESTA SUSTITUIDO EN EL GRUPO HIDROXILO DE LA POSICION 4, 5, 6 O 7 Y QUE TIENE LA FORMULA EN LA CUAL LOS SIMBOLOS DE A, R1, R2 Y R3 TIENEN EL SIGNIFICADO QUE SE INDICA EN LA MEMORIA DESCRIPTIVA. PREFERIBLEMENTE EL PORTADOR ES UNA PROTEINA. LOS CONJUGADOS OBTENIDOS SON UTILES COMO MATRICES DE AFINIDAS BIOLOGICAMENTE ACTIVAS PARA LA PURIFICACION DE ANTICUERPOS O DE RECEPTORES DE HORMONAS BIOLOGICAMENTE IMPORTANTES.
ES8802228A 1985-08-23 1988-07-15 Un metodo para preparar conjugados de indol-portador biologicamente activos. Expired ES2007265A6 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DK384085A DK158224C (da) 1985-08-23 1985-08-23 Fremgangsmaade til fremstilling af indolderivater

Publications (1)

Publication Number Publication Date
ES2007265A6 true ES2007265A6 (es) 1989-06-01

Family

ID=8127345

Family Applications (2)

Application Number Title Priority Date Filing Date
ES8601295A Expired ES2002723A6 (es) 1985-08-23 1986-08-22 Un metodo para preparar indoles o derivados del indol
ES8802228A Expired ES2007265A6 (es) 1985-08-23 1988-07-15 Un metodo para preparar conjugados de indol-portador biologicamente activos.

Family Applications Before (1)

Application Number Title Priority Date Filing Date
ES8601295A Expired ES2002723A6 (es) 1985-08-23 1986-08-22 Un metodo para preparar indoles o derivados del indol

Country Status (7)

Country Link
EP (1) EP0216162A3 (es)
JP (1) JPS62103064A (es)
AU (1) AU590603B2 (es)
DE (1) DE216162T1 (es)
DK (1) DK158224C (es)
ES (2) ES2002723A6 (es)
FI (1) FI87560C (es)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2264177C (en) 1996-08-30 2015-03-17 Upfront Chromatography A/S Isolation of immunoglobulins
SE9604487D0 (sv) * 1996-12-05 1996-12-05 Pharmacia & Upjohn Ab An antibody, a derivatized diagnostic marker, an immunoassay utilizing the antibody, and diagnostic method
WO1998047870A1 (en) * 1997-04-24 1998-10-29 American Home Products Corporation Process for the synthesis of 4-[6-(hexylcarbamoyloxy) hexylcarbamoyloxy]-piperidine-1- carboxylic acid 4-phenoxyphenyl ester
AUPP405098A0 (en) * 1998-06-12 1998-07-02 Access Pharmaceuticals Australia Pty Limited Novel methods of preparation of vitamin b12 derivatives suitable for conjugation to pharmaceuticals
KR101275770B1 (ko) * 2009-09-11 2013-06-14 숙명여자대학교산학협력단 ＰＰＡＲα/γ/δ 효능제로 작용하는 알콕시 인돌-3-아세트산 유도체, 이의 제조방법 및 이를 유효성분으로 함유하는 약학적 조성물

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CH526542A (de) * 1970-03-12 1972-08-15 Sandoz Ag Verfahren zur Herstellung neuer Indolderivate
US4141987A (en) * 1974-06-05 1979-02-27 Imperial Chemical Industries Limited 1-Aryloxy-3-thenamidoalkylamino-2-propanol derivatives

Also Published As

Publication number Publication date
DK158224C (da) 1990-09-24
DK384085A (da) 1987-02-24
FI863417A0 (fi) 1986-08-22
FI87560B (fi) 1992-10-15
FI863417A7 (fi) 1987-02-24
JPS62103064A (ja) 1987-05-13
ES2002723A6 (es) 1988-10-01
DE216162T1 (de) 1987-11-26
DK384085D0 (da) 1985-08-23
AU590603B2 (en) 1989-11-09
EP0216162A3 (en) 1989-03-15
FI87560C (fi) 1993-01-25
DK158224B (da) 1990-04-16
EP0216162A2 (en) 1987-04-01
AU6174786A (en) 1987-02-26

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Legal Events

Date Code Title Description
FD1A Patent lapsed

Effective date: 20010201