DK1652836T3 - Aminosyrediamider i non-alfa-stilling, som egner sig som adjuvanser til administration af aktrive biologiske midler - Google Patents
Aminosyrediamider i non-alfa-stilling, som egner sig som adjuvanser til administration af aktrive biologiske midlerInfo
- Publication number
- DK1652836T3 DK1652836T3 DK04742074T DK04742074T DK1652836T3 DK 1652836 T3 DK1652836 T3 DK 1652836T3 DK 04742074 T DK04742074 T DK 04742074T DK 04742074 T DK04742074 T DK 04742074T DK 1652836 T3 DK1652836 T3 DK 1652836T3
- Authority
- DK
- Denmark
- Prior art keywords
- adjuvants
- administration
- amino acid
- acid diamides
- biological agents
- Prior art date
Links
- -1 Amino acid diamides Chemical class 0.000 title abstract 2
- 239000002671 adjuvant Substances 0.000 title abstract 2
- 239000003124 biologic agent Substances 0.000 title 1
- 239000003814 drug Substances 0.000 abstract 2
- 229940079593 drug Drugs 0.000 abstract 2
- 229910052736 halogen Inorganic materials 0.000 abstract 2
- 150000002367 halogens Chemical class 0.000 abstract 2
- 238000004519 manufacturing process Methods 0.000 abstract 2
- 206010020751 Hypersensitivity Diseases 0.000 abstract 1
- 206010061218 Inflammation Diseases 0.000 abstract 1
- 206010028980 Neoplasm Diseases 0.000 abstract 1
- 239000013543 active substance Substances 0.000 abstract 1
- 125000000217 alkyl group Chemical group 0.000 abstract 1
- 208000026935 allergic disease Diseases 0.000 abstract 1
- 230000007815 allergy Effects 0.000 abstract 1
- 230000002785 anti-thrombosis Effects 0.000 abstract 1
- 239000003146 anticoagulant agent Substances 0.000 abstract 1
- 201000011510 cancer Diseases 0.000 abstract 1
- 150000001470 diamides Chemical class 0.000 abstract 1
- 201000010099 disease Diseases 0.000 abstract 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 abstract 1
- 125000000524 functional group Chemical group 0.000 abstract 1
- 230000004054 inflammatory process Effects 0.000 abstract 1
- 238000002483 medication Methods 0.000 abstract 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/16—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing nitrogen, e.g. nitro-, nitroso-, azo-compounds, nitriles, cyanates
- A61K47/18—Amines; Amides; Ureas; Quaternary ammonium compounds; Amino acids; Oligopeptides having up to five amino acids
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C237/00—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups
- C07C237/28—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups having the carbon atom of at least one of the carboxamide groups bound to a carbon atom of a non-condensed six-membered aromatic ring of the carbon skeleton
- C07C237/42—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups having the carbon atom of at least one of the carboxamide groups bound to a carbon atom of a non-condensed six-membered aromatic ring of the carbon skeleton having nitrogen atoms of amino groups bound to the carbon skeleton of the acid part, further acylated
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/16—Amides, e.g. hydroxamic acids
- A61K31/164—Amides, e.g. hydroxamic acids of a carboxylic acid with an aminoalcohol, e.g. ceramides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/16—Amides, e.g. hydroxamic acids
- A61K31/17—Amides, e.g. hydroxamic acids having the group >N—C(O)—N< or >N—C(S)—N<, e.g. urea, thiourea, carmustine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/08—Antiallergic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C233/00—Carboxylic acid amides
- C07C233/64—Carboxylic acid amides having carbon atoms of carboxamide groups bound to carbon atoms of six-membered aromatic rings
- C07C233/81—Carboxylic acid amides having carbon atoms of carboxamide groups bound to carbon atoms of six-membered aromatic rings having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by carboxyl groups
- C07C233/82—Carboxylic acid amides having carbon atoms of carboxamide groups bound to carbon atoms of six-membered aromatic rings having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by carboxyl groups with the substituted hydrocarbon radical bound to the nitrogen atom of the carboxamide group by an acyclic carbon atom
- C07C233/83—Carboxylic acid amides having carbon atoms of carboxamide groups bound to carbon atoms of six-membered aromatic rings having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by carboxyl groups with the substituted hydrocarbon radical bound to the nitrogen atom of the carboxamide group by an acyclic carbon atom of an acyclic saturated carbon skeleton
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C235/00—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms
- C07C235/42—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms having carbon atoms of carboxamide groups bound to carbon atoms of six-membered aromatic rings and singly-bound oxygen atoms bound to the same carbon skeleton
- C07C235/44—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms having carbon atoms of carboxamide groups bound to carbon atoms of six-membered aromatic rings and singly-bound oxygen atoms bound to the same carbon skeleton with carbon atoms of carboxamide groups and singly-bound oxygen atoms bound to carbon atoms of the same non-condensed six-membered aromatic ring
- C07C235/56—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms having carbon atoms of carboxamide groups bound to carbon atoms of six-membered aromatic rings and singly-bound oxygen atoms bound to the same carbon skeleton with carbon atoms of carboxamide groups and singly-bound oxygen atoms bound to carbon atoms of the same non-condensed six-membered aromatic ring having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a six-membered aromatic ring
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C235/00—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms
- C07C235/42—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms having carbon atoms of carboxamide groups bound to carbon atoms of six-membered aromatic rings and singly-bound oxygen atoms bound to the same carbon skeleton
- C07C235/44—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms having carbon atoms of carboxamide groups bound to carbon atoms of six-membered aromatic rings and singly-bound oxygen atoms bound to the same carbon skeleton with carbon atoms of carboxamide groups and singly-bound oxygen atoms bound to carbon atoms of the same non-condensed six-membered aromatic ring
- C07C235/58—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms having carbon atoms of carboxamide groups bound to carbon atoms of six-membered aromatic rings and singly-bound oxygen atoms bound to the same carbon skeleton with carbon atoms of carboxamide groups and singly-bound oxygen atoms bound to carbon atoms of the same non-condensed six-membered aromatic ring with carbon atoms of carboxamide groups and singly-bound oxygen atoms, bound in ortho-position to carbon atoms of the same non-condensed six-membered aromatic ring
- C07C235/64—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms having carbon atoms of carboxamide groups bound to carbon atoms of six-membered aromatic rings and singly-bound oxygen atoms bound to the same carbon skeleton with carbon atoms of carboxamide groups and singly-bound oxygen atoms bound to carbon atoms of the same non-condensed six-membered aromatic ring with carbon atoms of carboxamide groups and singly-bound oxygen atoms, bound in ortho-position to carbon atoms of the same non-condensed six-membered aromatic ring having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a six-membered aromatic ring
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Engineering & Computer Science (AREA)
- Epidemiology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Diabetes (AREA)
- Pain & Pain Management (AREA)
- Rheumatology (AREA)
- Hematology (AREA)
- Pulmonology (AREA)
- Immunology (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
- Cosmetics (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| ES200301781A ES2222822B1 (es) | 2003-07-28 | 2003-07-28 | Diamidas de aminoacidos en posicion no alfa utiles como adyuvantes para la administracion de agentes biologicos activos. |
| PCT/ES2004/000346 WO2005012230A1 (fr) | 2003-07-28 | 2004-07-23 | Diamides d'aminoacides en position non $g(a) utilises en tant qu'adjuvants pour l'administration d'agents biologiques actifs |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DK1652836T3 true DK1652836T3 (da) | 2007-11-05 |
Family
ID=34112519
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK04742074T DK1652836T3 (da) | 2003-07-28 | 2004-07-23 | Aminosyrediamider i non-alfa-stilling, som egner sig som adjuvanser til administration af aktrive biologiske midler |
Country Status (17)
| Country | Link |
|---|---|
| US (1) | US7462735B2 (fr) |
| EP (1) | EP1652836B1 (fr) |
| JP (1) | JP4343227B2 (fr) |
| KR (1) | KR100970216B1 (fr) |
| CN (1) | CN100475776C (fr) |
| AT (1) | ATE367373T1 (fr) |
| AU (1) | AU2004261417C1 (fr) |
| BR (1) | BRPI0413032A (fr) |
| CA (1) | CA2533639A1 (fr) |
| DE (1) | DE602004007665T2 (fr) |
| DK (1) | DK1652836T3 (fr) |
| ES (2) | ES2222822B1 (fr) |
| PL (1) | PL1652836T3 (fr) |
| PT (1) | PT1652836E (fr) |
| RU (1) | RU2368599C2 (fr) |
| WO (1) | WO2005012230A1 (fr) |
| ZA (1) | ZA200600165B (fr) |
Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP2060253A1 (fr) | 2007-11-14 | 2009-05-20 | Laboratorios Farmaceuticos Rovi, S.A. | Formes pharmaceutiques pour la libération de composés actifs |
| ES2296529B1 (es) * | 2006-08-07 | 2009-04-01 | Laboratorios Farmaceuticos Rovi, S.A. | Composicion farmaceutica con promotores de absorcion. |
| EP2213282A1 (fr) | 2009-01-30 | 2010-08-04 | Laboratorios Farmaceuticos Rovi, S.A. | Formes pharmaceutiques pour la libération de composés actifs |
| US8802156B2 (en) | 2007-11-14 | 2014-08-12 | Laboratorios Farmacéuticos Rovi, S.A. | Pharmaceutical forms for the release of active compounds |
| CN104230745B (zh) * | 2014-07-10 | 2016-06-22 | 南京医科大学 | 一类n-苄基取代的氨基水杨酸与4-氨基丁酸的酰胺衍生物及其药物用途 |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6001347A (en) * | 1995-03-31 | 1999-12-14 | Emisphere Technologies, Inc. | Compounds and compositions for delivering active agents |
| US6358504B1 (en) * | 1997-02-07 | 2002-03-19 | Emisphere Technologies, Inc. | Compounds and compositions for delivering active agents |
| KR100659753B1 (ko) * | 1998-08-07 | 2006-12-20 | 에미스페어 테크놀로지스, 인코포레이티드 | 활성제 전달용 화합물 및 조성물 |
| WO2000031536A2 (fr) * | 1998-11-23 | 2000-06-02 | President And Fellows Of Harvard College | Detection d'informations structurelles ou synthetiques concernant des composes chimiques |
| SE0102764D0 (sv) * | 2001-08-17 | 2001-08-17 | Astrazeneca Ab | Compounds |
-
2003
- 2003-07-28 ES ES200301781A patent/ES2222822B1/es not_active Expired - Lifetime
-
2004
- 2004-07-23 DE DE602004007665T patent/DE602004007665T2/de not_active Expired - Lifetime
- 2004-07-23 AU AU2004261417A patent/AU2004261417C1/en not_active Ceased
- 2004-07-23 US US10/563,994 patent/US7462735B2/en not_active Expired - Fee Related
- 2004-07-23 ZA ZA200600165A patent/ZA200600165B/xx unknown
- 2004-07-23 PT PT04742074T patent/PT1652836E/pt unknown
- 2004-07-23 DK DK04742074T patent/DK1652836T3/da active
- 2004-07-23 WO PCT/ES2004/000346 patent/WO2005012230A1/fr active IP Right Grant
- 2004-07-23 JP JP2006521597A patent/JP4343227B2/ja not_active Expired - Fee Related
- 2004-07-23 CA CA002533639A patent/CA2533639A1/fr not_active Abandoned
- 2004-07-23 RU RU2006101630/04A patent/RU2368599C2/ru not_active IP Right Cessation
- 2004-07-23 PL PL04742074T patent/PL1652836T3/pl unknown
- 2004-07-23 KR KR1020067001803A patent/KR100970216B1/ko not_active IP Right Cessation
- 2004-07-23 EP EP04742074A patent/EP1652836B1/fr not_active Expired - Lifetime
- 2004-07-23 AT AT04742074T patent/ATE367373T1/de active
- 2004-07-23 CN CNB2004800220400A patent/CN100475776C/zh not_active Expired - Fee Related
- 2004-07-23 ES ES04742074T patent/ES2289534T3/es not_active Expired - Lifetime
- 2004-07-23 BR BRPI0413032-4A patent/BRPI0413032A/pt not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| PL1652836T3 (pl) | 2007-12-31 |
| JP4343227B2 (ja) | 2009-10-14 |
| RU2006101630A (ru) | 2007-09-10 |
| AU2004261417B2 (en) | 2010-07-01 |
| ZA200600165B (en) | 2007-03-28 |
| WO2005012230A1 (fr) | 2005-02-10 |
| PT1652836E (pt) | 2007-10-23 |
| ES2222822A1 (es) | 2005-02-01 |
| EP1652836B1 (fr) | 2007-07-18 |
| AU2004261417C1 (en) | 2011-02-24 |
| DE602004007665D1 (de) | 2007-08-30 |
| JP2007533600A (ja) | 2007-11-22 |
| BRPI0413032A (pt) | 2006-10-03 |
| ES2222822B1 (es) | 2005-12-16 |
| DE602004007665T2 (de) | 2008-05-15 |
| KR100970216B1 (ko) | 2010-07-16 |
| CN100475776C (zh) | 2009-04-08 |
| RU2368599C2 (ru) | 2009-09-27 |
| EP1652836A1 (fr) | 2006-05-03 |
| CN1829682A (zh) | 2006-09-06 |
| AU2004261417A1 (en) | 2005-02-10 |
| US7462735B2 (en) | 2008-12-09 |
| US20070191302A1 (en) | 2007-08-16 |
| CA2533639A1 (fr) | 2005-02-10 |
| ATE367373T1 (de) | 2007-08-15 |
| ES2289534T3 (es) | 2008-02-01 |
| KR20060079184A (ko) | 2006-07-05 |
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