DK163578A - 2!-hydroxy-2-(5-isoxazolylmethyl)-6,7-benzomorphaner og syreag dditionssalte heraf samt fremgangsmaade til deres fremstillin - Google Patents

2!-hydroxy-2-(5-isoxazolylmethyl)-6,7-benzomorphaner og syreag dditionssalte heraf samt fremgangsmaade til deres fremstillin

Info

Publication number
DK163578A
DK163578A DK163578A DK163578A DK163578A DK 163578 A DK163578 A DK 163578A DK 163578 A DK163578 A DK 163578A DK 163578 A DK163578 A DK 163578A DK 163578 A DK163578 A DK 163578A
Authority
DK
Denmark
Prior art keywords
reagition
benzomorphanes
isoxazolylmethyl
hydroxy
salts
Prior art date
Application number
DK163578A
Other languages
English (en)
Other versions
DK144678C (da
DK144678B (da
Inventor
H Merz
K Stockhaus
Original Assignee
Boehringer Sohn Ingelheim
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Boehringer Sohn Ingelheim filed Critical Boehringer Sohn Ingelheim
Publication of DK163578A publication Critical patent/DK163578A/da
Publication of DK144678B publication Critical patent/DK144678B/da
Application granted granted Critical
Publication of DK144678C publication Critical patent/DK144678C/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
    • C07D413/06—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/02—Suppositories; Bougies; Bases therefor; Ovules
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/08—Solutions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2013—Organic compounds, e.g. phospholipids, fats
    • A61K9/2018—Sugars, or sugar alcohols, e.g. lactose, mannitol; Derivatives thereof, e.g. polysorbates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/28—Dragees; Coated pills or tablets, e.g. with film or compression coating
    • A61K9/2806—Coating materials
    • A61K9/2833—Organic macromolecular compounds
    • A61K9/286—Polysaccharides, e.g. gums; Cyclodextrin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Organic Chemistry (AREA)
  • Epidemiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Dermatology (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Pain & Pain Management (AREA)
  • General Chemical & Material Sciences (AREA)
  • Neurosurgery (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Plural Heterocyclic Compounds (AREA)
DK163578A 1977-04-15 1978-04-14 Analogifremgangsmaade til fremstilling af 2'-hydroxy-2-(5-isoxazolylmethyl)-6,7-benzomorphaner eller syreadditionssalte heraf DK144678C (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE2716687 1977-04-15
DE19772716687 DE2716687A1 (de) 1977-04-15 1977-04-15 2'-hydroxy-2-(5-isoxazolylmethyl)-6,7benzomorphane, deren saeureadditionssalze und diese enthaltende arzneimittel

Publications (3)

Publication Number Publication Date
DK163578A true DK163578A (da) 1978-10-16
DK144678B DK144678B (da) 1982-05-10
DK144678C DK144678C (da) 1982-10-11

Family

ID=6006359

Family Applications (1)

Application Number Title Priority Date Filing Date
DK163578A DK144678C (da) 1977-04-15 1978-04-14 Analogifremgangsmaade til fremstilling af 2'-hydroxy-2-(5-isoxazolylmethyl)-6,7-benzomorphaner eller syreadditionssalte heraf

Country Status (25)

Country Link
US (1) US4133888A (da)
JP (1) JPS53130671A (da)
AT (3) AT358192B (da)
AU (1) AU514938B2 (da)
BE (1) BE866013A (da)
CA (1) CA1079726A (da)
CH (1) CH638519A5 (da)
DE (1) DE2716687A1 (da)
DK (1) DK144678C (da)
ES (3) ES468798A1 (da)
FI (1) FI63399C (da)
FR (1) FR2387228A1 (da)
GB (1) GB1575156A (da)
GR (1) GR64819B (da)
IE (1) IE46722B1 (da)
IL (1) IL54509A (da)
IT (1) IT1102595B (da)
LU (1) LU79430A1 (da)
NL (1) NL7803977A (da)
NO (1) NO148418C (da)
NZ (1) NZ186971A (da)
PH (1) PH13854A (da)
PT (1) PT67907B (da)
SE (1) SE430160B (da)
ZA (1) ZA782149B (da)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1575009A (en) * 1976-06-21 1980-09-17 Acf Chemiefarma Nv 6,7-benzomorphan derivatives
NL7907800A (nl) 1979-10-23 1981-04-27 Acf Chemiefarma Nv Nieuwe 6,7-benzomorfanderivaten en zuuradditiezouten daarvan, farmaceutische preparaten die een dergelijke verbinding bevatten, alsmede werkwijze voor het bereiden van deze verbindingen en de farmaceutische preparaten.

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3499906A (en) * 1966-05-20 1970-03-10 Merck & Co Inc 5,9-diethyl-2'-hydroxy-2-substituted-6,7-benzomorphans
CS166804B2 (da) * 1971-02-08 1976-03-29 Boehringer Sohn Ingelheim
US3853889A (en) * 1973-07-18 1974-12-10 Bristol Myers Co 3,14-substituted-8-oxamorphinans
DE2411382C3 (de) * 1974-03-09 1979-09-06 C.H. Boehringer Sohn, 6507 Ingelheim 2-Tetrahydrofurfuryl-6,7-benzomorphane, Verfahren zur Herstellung und deren Verwendung
DE2437610A1 (de) * 1974-08-05 1976-02-26 Boehringer Sohn Ingelheim Neue 5,9-beta-disubstituierte 2-tetrahydrofurfuryl-6,7-benzomorphane, deren saeureadditionssalze, ihre verwendung als arzneimittel und verfahren zu deren herstellung

Also Published As

Publication number Publication date
ES472407A1 (es) 1979-04-01
ATA552079A (de) 1980-06-15
IE46722B1 (en) 1983-09-07
ES468798A1 (es) 1978-12-01
FR2387228A1 (fr) 1978-11-10
CA1079726A (en) 1980-06-17
ES472408A1 (es) 1979-04-01
SE430160B (sv) 1983-10-24
GR64819B (en) 1980-06-03
CH638519A5 (de) 1983-09-30
DK144678C (da) 1982-10-11
PH13854A (en) 1980-10-22
IE780742L (en) 1978-10-15
DE2716687A1 (de) 1978-10-19
FI781025A (fi) 1978-10-16
AU3509878A (en) 1979-10-18
BE866013A (fr) 1978-10-16
ATA551979A (de) 1980-06-15
GB1575156A (en) 1980-09-17
FR2387228B1 (da) 1981-05-29
US4133888A (en) 1979-01-09
ATA241978A (de) 1980-01-15
DK144678B (da) 1982-05-10
IT1102595B (it) 1985-10-07
NL7803977A (nl) 1978-10-17
AT360666B (de) 1981-01-26
AT360667B (de) 1981-01-26
JPS53130671A (en) 1978-11-14
LU79430A1 (de) 1979-05-25
PT67907B (fr) 1980-06-16
AT358192B (de) 1980-08-25
FI63399C (fi) 1983-06-10
NO781310L (no) 1978-10-17
FI63399B (fi) 1983-02-28
IL54509A (en) 1982-04-30
AU514938B2 (en) 1981-03-05
NO148418C (no) 1983-10-05
NO148418B (no) 1983-06-27
NZ186971A (en) 1980-10-24
IT7848887A0 (it) 1978-04-13
ZA782149B (en) 1979-12-27
IL54509A0 (en) 1978-07-31
PT67907A (fr) 1978-05-01
SE7804260L (sv) 1978-10-16

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