IL54509A - 2'-hydroxy-2-(5-isoxazolylmethyl)-6,7-benzomorphanes,their preparation and pharmaceutical compositions containing them - Google Patents

2'-hydroxy-2-(5-isoxazolylmethyl)-6,7-benzomorphanes,their preparation and pharmaceutical compositions containing them

Info

Publication number
IL54509A
IL54509A IL54509A IL5450978A IL54509A IL 54509 A IL54509 A IL 54509A IL 54509 A IL54509 A IL 54509A IL 5450978 A IL5450978 A IL 5450978A IL 54509 A IL54509 A IL 54509A
Authority
IL
Israel
Prior art keywords
benzomorphanes
isoxazolylmethyl
hydroxy
preparation
pharmaceutical compositions
Prior art date
Application number
IL54509A
Other languages
English (en)
Other versions
IL54509A0 (en
Original Assignee
Boehringer Sohn Ingelheim
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Boehringer Sohn Ingelheim filed Critical Boehringer Sohn Ingelheim
Publication of IL54509A0 publication Critical patent/IL54509A0/xx
Publication of IL54509A publication Critical patent/IL54509A/xx

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D413/00Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/02Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
    • C07D413/06Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0019Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/02Suppositories; Bougies; Bases therefor; Ovules
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/08Solutions
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/20Pills, tablets, discs, rods
    • A61K9/2004Excipients; Inactive ingredients
    • A61K9/2013Organic compounds, e.g. phospholipids, fats
    • A61K9/2018Sugars, or sugar alcohols, e.g. lactose, mannitol; Derivatives thereof, e.g. polysorbates
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/20Pills, tablets, discs, rods
    • A61K9/28Dragees; Coated pills or tablets, e.g. with film or compression coating
    • A61K9/2806Coating materials
    • A61K9/2833Organic macromolecular compounds
    • A61K9/286Polysaccharides, e.g. gums; Cyclodextrin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/04Centrally acting analgesics, e.g. opioids

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Organic Chemistry (AREA)
  • Epidemiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Dermatology (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Pain & Pain Management (AREA)
  • General Chemical & Material Sciences (AREA)
  • Neurosurgery (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Plural Heterocyclic Compounds (AREA)
IL54509A 1977-04-15 1978-04-14 2'-hydroxy-2-(5-isoxazolylmethyl)-6,7-benzomorphanes,their preparation and pharmaceutical compositions containing them IL54509A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19772716687 DE2716687A1 (de) 1977-04-15 1977-04-15 2'-hydroxy-2-(5-isoxazolylmethyl)-6,7benzomorphane, deren saeureadditionssalze und diese enthaltende arzneimittel

Publications (2)

Publication Number Publication Date
IL54509A0 IL54509A0 (en) 1978-07-31
IL54509A true IL54509A (en) 1982-04-30

Family

ID=6006359

Family Applications (1)

Application Number Title Priority Date Filing Date
IL54509A IL54509A (en) 1977-04-15 1978-04-14 2'-hydroxy-2-(5-isoxazolylmethyl)-6,7-benzomorphanes,their preparation and pharmaceutical compositions containing them

Country Status (25)

Country Link
US (1) US4133888A (xx)
JP (1) JPS53130671A (xx)
AT (3) AT358192B (xx)
AU (1) AU514938B2 (xx)
BE (1) BE866013A (xx)
CA (1) CA1079726A (xx)
CH (1) CH638519A5 (xx)
DE (1) DE2716687A1 (xx)
DK (1) DK144678C (xx)
ES (3) ES468798A1 (xx)
FI (1) FI63399C (xx)
FR (1) FR2387228A1 (xx)
GB (1) GB1575156A (xx)
GR (1) GR64819B (xx)
IE (1) IE46722B1 (xx)
IL (1) IL54509A (xx)
IT (1) IT1102595B (xx)
LU (1) LU79430A1 (xx)
NL (1) NL7803977A (xx)
NO (1) NO148418C (xx)
NZ (1) NZ186971A (xx)
PH (1) PH13854A (xx)
PT (1) PT67907B (xx)
SE (1) SE430160B (xx)
ZA (1) ZA782149B (xx)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1575009A (en) * 1976-06-21 1980-09-17 Acf Chemiefarma Nv 6,7-benzomorphan derivatives
NL7907800A (nl) 1979-10-23 1981-04-27 Acf Chemiefarma Nv Nieuwe 6,7-benzomorfanderivaten en zuuradditiezouten daarvan, farmaceutische preparaten die een dergelijke verbinding bevatten, alsmede werkwijze voor het bereiden van deze verbindingen en de farmaceutische preparaten.

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3499906A (en) * 1966-05-20 1970-03-10 Merck & Co Inc 5,9-diethyl-2'-hydroxy-2-substituted-6,7-benzomorphans
CS166804B2 (xx) * 1971-02-08 1976-03-29 Boehringer Sohn Ingelheim
US3853889A (en) * 1973-07-18 1974-12-10 Bristol Myers Co 3,14-substituted-8-oxamorphinans
DE2411382C3 (de) * 1974-03-09 1979-09-06 C.H. Boehringer Sohn, 6507 Ingelheim 2-Tetrahydrofurfuryl-6,7-benzomorphane, Verfahren zur Herstellung und deren Verwendung
DE2437610A1 (de) * 1974-08-05 1976-02-26 Boehringer Sohn Ingelheim Neue 5,9-beta-disubstituierte 2-tetrahydrofurfuryl-6,7-benzomorphane, deren saeureadditionssalze, ihre verwendung als arzneimittel und verfahren zu deren herstellung

Also Published As

Publication number Publication date
ES472407A1 (es) 1979-04-01
ATA552079A (de) 1980-06-15
IE46722B1 (en) 1983-09-07
ES468798A1 (es) 1978-12-01
FR2387228A1 (fr) 1978-11-10
CA1079726A (en) 1980-06-17
ES472408A1 (es) 1979-04-01
SE430160B (sv) 1983-10-24
GR64819B (en) 1980-06-03
CH638519A5 (de) 1983-09-30
DK144678C (da) 1982-10-11
PH13854A (en) 1980-10-22
IE780742L (en) 1978-10-15
DE2716687A1 (de) 1978-10-19
FI781025A (fi) 1978-10-16
AU3509878A (en) 1979-10-18
BE866013A (fr) 1978-10-16
ATA551979A (de) 1980-06-15
GB1575156A (en) 1980-09-17
DK163578A (da) 1978-10-16
FR2387228B1 (xx) 1981-05-29
US4133888A (en) 1979-01-09
ATA241978A (de) 1980-01-15
DK144678B (da) 1982-05-10
IT1102595B (it) 1985-10-07
NL7803977A (nl) 1978-10-17
AT360666B (de) 1981-01-26
AT360667B (de) 1981-01-26
JPS53130671A (en) 1978-11-14
LU79430A1 (de) 1979-05-25
PT67907B (fr) 1980-06-16
AT358192B (de) 1980-08-25
FI63399C (fi) 1983-06-10
NO781310L (no) 1978-10-17
FI63399B (fi) 1983-02-28
AU514938B2 (en) 1981-03-05
NO148418C (no) 1983-10-05
NO148418B (no) 1983-06-27
NZ186971A (en) 1980-10-24
IT7848887A0 (it) 1978-04-13
ZA782149B (en) 1979-12-27
IL54509A0 (en) 1978-07-31
PT67907A (fr) 1978-05-01
SE7804260L (sv) 1978-10-16

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