NO823374L - 3-oksoestra-17-acetonitril og umettede analoger, samt fremgangsmaate for deres fremstilling - Google Patents

3-oksoestra-17-acetonitril og umettede analoger, samt fremgangsmaate for deres fremstilling

Info

Publication number
NO823374L
NO823374L NO823374A NO823374A NO823374L NO 823374 L NO823374 L NO 823374L NO 823374 A NO823374 A NO 823374A NO 823374 A NO823374 A NO 823374A NO 823374 L NO823374 L NO 823374L
Authority
NO
Norway
Prior art keywords
oxoestra
acetonitril
procedure
preparation
saturated analogs
Prior art date
Application number
NO823374A
Other languages
English (en)
Inventor
George Richard Lenz
Original Assignee
Searle & Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Searle & Co filed Critical Searle & Co
Publication of NO823374L publication Critical patent/NO823374L/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J41/00—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring
    • C07J41/0033—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring not covered by C07J41/0005
    • C07J41/0094—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring not covered by C07J41/0005 containing nitrile radicals, including thiocyanide radicals

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Toxicology (AREA)
  • General Health & Medical Sciences (AREA)
  • Steroid Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
NO823374A 1981-10-09 1982-10-08 3-oksoestra-17-acetonitril og umettede analoger, samt fremgangsmaate for deres fremstilling NO823374L (no)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US06/310,204 US4389345A (en) 1981-10-09 1981-10-09 3-Oxoestra-17-acetonitrile and unsaturated analogs

Publications (1)

Publication Number Publication Date
NO823374L true NO823374L (no) 1983-04-11

Family

ID=23201436

Family Applications (1)

Application Number Title Priority Date Filing Date
NO823374A NO823374L (no) 1981-10-09 1982-10-08 3-oksoestra-17-acetonitril og umettede analoger, samt fremgangsmaate for deres fremstilling

Country Status (9)

Country Link
US (1) US4389345A (no)
EP (1) EP0077040A1 (no)
JP (1) JPS5872600A (no)
AU (1) AU8923282A (no)
DK (1) DK446982A (no)
ES (1) ES516372A0 (no)
NO (1) NO823374L (no)
PT (1) PT75664B (no)
ZA (1) ZA827381B (no)

Families Citing this family (23)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2724174B1 (fr) * 1994-09-06 1997-01-17 Roussel Uclaf Procede de preparation d'un derive steroide 17beta-carboxy et nouveaux intermediaires
DE10043846A1 (de) * 2000-09-04 2002-04-04 Jenapharm Gmbh 17-Methylensteroide, Verfahren zu deren Herstellung und diese Verbindung enthaltende pharmazeutische Zusammensetzungen
WO2012116290A2 (en) * 2011-02-25 2012-08-30 Washington University Neuroactive 17(20)-z-vinylcyano-substituted steroids, prodrugs thereof, and methods of treatment using same
WO2013056181A1 (en) 2011-10-14 2013-04-18 Sage Therapeutics, Inc. 3,3 disubstituted 19-nor pregnane compounds, compositions, and uses thereof
TR201808616T4 (tr) 2012-12-18 2018-07-23 Sage Therapeutics Inc Nöroaktif 19-alkoksi-17-ikameli steroidler, bunların ön ilaçları ve bunları kullanan tedavi yöntemleri.
US9512170B2 (en) 2013-03-01 2016-12-06 Washington University Neuroactive 13, 17-substituted steroids as modulators for GABA type-A receptors
US9365502B2 (en) 2013-03-11 2016-06-14 Washington University Neuroactive substituted cyclopenta[b]phenanthrenes as modulators for GABA type-A receptors
US9562026B2 (en) 2013-03-14 2017-02-07 Washington University Neuroactive substituted cyclopent[a]anthracenes as modulators for GABA type-A receptors
CN105246909B (zh) 2013-04-17 2020-10-13 萨奇治疗股份有限公司 刺激神经活性的19-去甲类固醇及其使用方法
US20160068563A1 (en) 2013-04-17 2016-03-10 Boyd L. Harrison 19-nor neuroactive steroids and methods of use thereof
KR20230172622A (ko) 2013-04-17 2023-12-22 세이지 테라퓨틱스, 인크. 19-노르 c3,3-이치환된 c21-n-피라졸릴 스테로이드 및 그의 사용 방법
US9725481B2 (en) 2013-04-17 2017-08-08 Sage Therapeutics, Inc. 19-nor C3, 3-disubstituted C21-C-bound heteroaryl steroids and methods of use thereof
WO2015010054A2 (en) 2013-07-19 2015-01-22 Sage Therapeutics, Inc. Neuroactive steroids, compositions, and uses thereof
PT3035940T (pt) 2013-08-23 2019-01-28 Sage Therapeutics Inc Esteroides neuroativos, composições e seus usos
US10246482B2 (en) 2014-06-18 2019-04-02 Sage Therapeutics, Inc. Neuroactive steroids, compositions, and uses thereof
SI3206493T1 (sl) 2014-10-16 2020-10-30 Sage Therapeutics, Inc. Sestavki in metode za zdravljenje CNS motenj
CN112940066A (zh) 2014-10-16 2021-06-11 萨奇治疗股份有限公司 靶向cns障碍的组合物和方法
ME03749B (me) 2014-11-27 2021-04-20 Sage Therapeutics Inc KOMPOZICIJE I POSTUPCIZA LEČENJE POREMEĆAJA CNS-a
DK3250210T3 (da) 2015-01-26 2021-03-08 Sage Therapeutics Inc Sammensætninger og fremgangsmåder til behandling af cns-forstyrrelser
DK3258939T3 (da) 2015-02-20 2022-12-12 Sage Therapeutics Inc Neuroaktive steroider, sammensætninger og anvendelser heraf
IL309259A (en) 2016-07-11 2024-02-01 Sage Therapeutics Inc C17, C20 and C21 converted neuroactive steroids and methods of using them
EP4406602A2 (en) 2016-07-11 2024-07-31 Sage Therapeutics, Inc. C7, c12, and c16 substituted neuroactive steroids and their methods of use
PE20230244A1 (es) 2019-05-31 2023-02-07 Sage Therapeutics Inc Esteroides neuroactivos y composiciones de estos

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2336438C2 (de) * 1973-07-14 1983-07-07 Schering Ag, 1000 Berlin Und 4619 Bergkamen Verfahren zur Herstellung von 17 β- Oxalylsteroiden

Also Published As

Publication number Publication date
ES8401496A1 (es) 1983-12-16
PT75664B (en) 1985-01-11
JPS5872600A (ja) 1983-04-30
US4389345A (en) 1983-06-21
PT75664A (en) 1982-11-01
ZA827381B (en) 1983-11-30
DK446982A (da) 1983-04-10
EP0077040A1 (en) 1983-04-20
AU8923282A (en) 1983-04-14
ES516372A0 (es) 1983-12-16

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