DK163448C - Fremgangsmaade og apparat til frysning af et flydende medium til fremstilling af sfaeriske frosne partikler - Google Patents

Fremgangsmaade og apparat til frysning af et flydende medium til fremstilling af sfaeriske frosne partikler

Info

Publication number
DK163448C
DK163448C DK551282A DK551282A DK163448C DK 163448 C DK163448 C DK 163448C DK 551282 A DK551282 A DK 551282A DK 551282 A DK551282 A DK 551282A DK 163448 C DK163448 C DK 163448C
Authority
DK
Denmark
Prior art keywords
spheric
freezing
manufacture
liquid medium
frozen particles
Prior art date
Application number
DK551282A
Other languages
Danish (da)
English (en)
Other versions
DK551282A (da
DK163448B (da
Inventor
Ian Richard Buxton
James Marchant Peach
Original Assignee
Wyeth John & Brother Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Wyeth John & Brother Ltd filed Critical Wyeth John & Brother Ltd
Publication of DK551282A publication Critical patent/DK551282A/da
Publication of DK163448B publication Critical patent/DK163448B/da
Application granted granted Critical
Publication of DK163448C publication Critical patent/DK163448C/da

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1682—Processes
    • A61K9/1694—Processes resulting in granules or microspheres of the matrix type containing more than 5% of excipient
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61J—CONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
    • A61J3/00—Devices or methods specially adapted for bringing pharmaceutical products into particular physical or administering forms
    • A61J3/06—Devices or methods specially adapted for bringing pharmaceutical products into particular physical or administering forms into the form of pills, lozenges or dragees
    • F—MECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
    • F25—REFRIGERATION OR COOLING; COMBINED HEATING AND REFRIGERATION SYSTEMS; HEAT PUMP SYSTEMS; MANUFACTURE OR STORAGE OF ICE; LIQUEFACTION SOLIDIFICATION OF GASES
    • F25C—PRODUCING, WORKING OR HANDLING ICE
    • F25C1/00—Producing ice

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Public Health (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Physics & Mathematics (AREA)
  • Mechanical Engineering (AREA)
  • Thermal Sciences (AREA)
  • General Engineering & Computer Science (AREA)
  • Medicinal Preparation (AREA)
  • Glanulating (AREA)
  • Medical Preparation Storing Or Oral Administration Devices (AREA)
  • Manufacturing Of Micro-Capsules (AREA)
  • Drying Of Solid Materials (AREA)
DK551282A 1981-12-11 1982-12-10 Fremgangsmaade og apparat til frysning af et flydende medium til fremstilling af sfaeriske frosne partikler DK163448C (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB8137526 1981-12-11
GB8137526 1981-12-11

Publications (3)

Publication Number Publication Date
DK551282A DK551282A (da) 1983-06-12
DK163448B DK163448B (da) 1992-03-02
DK163448C true DK163448C (da) 1992-07-20

Family

ID=10526566

Family Applications (1)

Application Number Title Priority Date Filing Date
DK551282A DK163448C (da) 1981-12-11 1982-12-10 Fremgangsmaade og apparat til frysning af et flydende medium til fremstilling af sfaeriske frosne partikler

Country Status (21)

Country Link
US (1) US4470202A (fr)
EP (1) EP0081913B1 (fr)
JP (1) JPS58104628A (fr)
KR (1) KR880001208B1 (fr)
AR (1) AR229378A1 (fr)
AT (1) ATE14047T1 (fr)
AU (1) AU552072B2 (fr)
BR (1) BR8207186A (fr)
CA (1) CA1197700A (fr)
DE (1) DE3264450D1 (fr)
DK (1) DK163448C (fr)
ES (1) ES518081A0 (fr)
GB (1) GB2111184B (fr)
GR (1) GR77845B (fr)
HU (1) HU187197B (fr)
IE (1) IE53538B1 (fr)
IL (1) IL67401A (fr)
NZ (1) NZ202729A (fr)
PH (1) PH17895A (fr)
PT (1) PT75971B (fr)
ZA (1) ZA828740B (fr)

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US4693912A (en) * 1985-02-28 1987-09-15 Technicon Instruments Corporation Lyophilization of reagent-coated particles
US4646526A (en) * 1986-07-02 1987-03-03 Frick Company Method and apparatus for making fragmentary ice
EP0275114A3 (fr) * 1987-01-16 1990-05-30 Pieter Wynand Le Roux Murray Appareil cryogénique et procédés cryogéniques
US5044091B1 (en) * 1989-04-18 1997-12-30 Sankyo Co Method of preparing a freeze-dried formulation of a drug
US5019400A (en) * 1989-05-01 1991-05-28 Enzytech, Inc. Very low temperature casting of controlled release microspheres
AU8404091A (en) * 1990-08-06 1992-03-02 Paul Kateman Method and apparatus for producing and dispensing aerated products
US5219383A (en) * 1991-05-23 1993-06-15 Hoshizaki Denki Kabushiki Kaisha Ice making machine
DE4201172C1 (en) * 1992-01-17 1993-07-22 Alfatec-Pharma Gmbh, 6900 Heidelberg, De Pellets contg. Aloe vera extract - useful, e.g. as antiinflammatory of antibiotic agents, or for treating gastric ulcers
DE4201179A1 (de) * 1992-01-17 1993-07-22 Alfatec Pharma Gmbh Wirkstoff(e) enthaltendes granulat oder pellet mit einem geruest aus hydrophilen makromolekuelen und verfahren zu seiner herstellung
DE4201173C2 (de) * 1992-01-17 1998-10-29 Alfatec Pharma Gmbh Akutarzneimittel in Form von Dihydropyridinderivaten enthaltenden Pellets und ihre Herstellung
US5275016A (en) * 1992-04-24 1994-01-04 Abaxis, Inc. Cryogenic apparatus
AU679986B2 (en) * 1993-04-28 1997-07-17 N.V. Organon Lyospheres comprising gonadotropin
GB9511263D0 (en) * 1995-06-03 1995-07-26 Ici Plc Process for the production of a pyrotechnic or explosive device
GB2329124B (en) * 1997-09-12 2002-05-08 Hiran Asoka Malinga Ratwatte Method of forming dose units of active agents
GB2350582A (en) * 1999-06-01 2000-12-06 Hiran Asoka Malinga Ratwatte A method of tableting
DE19940795A1 (de) * 1999-08-27 2001-03-01 Lohmann Therapie Syst Lts Schnellzerfallende Pellets auf der Basis von Chitosan
US20040022861A1 (en) * 2001-01-30 2004-02-05 Williams Robert O. Process for production of nanoparticles and microparticles by spray freezing into liquid
JP2004517699A (ja) * 2001-01-30 2004-06-17 ボード オブ リージェンツ ユニバーシティ オブ テキサス システム 液体中への噴霧凍結によるナノ粒子およびミクロ粒子の製造方法
WO2003015783A1 (fr) * 2001-08-14 2003-02-27 Biotie Therapies Corporation Traitement de l'alcoolisme ou de l'abus d'alcool
US7413690B1 (en) 2003-10-29 2008-08-19 The University Of Mississippi Process and apparatus for producing spherical pellets using molten solid matrices
EP2322195A2 (fr) 2003-11-10 2011-05-18 Reprise Biopharmaceutics, LLC Compositions pharmaceutiques comportant de la desmopressine faiblement dosee
DE20321887U1 (de) 2003-11-10 2012-01-20 Allergan, Inc. Arzneimittel umfassend niedrige Dosierungen von Desmopressin
PT1530967E (pt) 2003-11-13 2006-09-29 Ferring Bv Embalagem blister e uma forma de dosagem solida que compreende desmopressina.
EP1870649A1 (fr) * 2006-06-20 2007-12-26 Octapharma AG Lyophilisation visant à obtenir une humidité résiduelle déterminée par énergie de désorption aux niveaux limités
MX2010008799A (es) 2008-03-05 2010-09-07 Sanofi Pasteur Proceso para estabilizar una composicion de vacuna que contiene adyuvante.
KR20100023538A (ko) * 2008-08-22 2010-03-04 삼성전자주식회사 고상 시약의 제조방법 및 고상 시약을 수용하는 미세유동장치
DE102009011521A1 (de) * 2009-03-06 2010-09-16 Wolfgang Folger Vorrichtung und Verfahren zur Herstellung von Eisperlen aus einem wässrigen Gemisch
WO2010134953A1 (fr) * 2009-05-18 2010-11-25 Robert Warren Système de lyophilisation modulaire
CN110582278B (zh) * 2017-03-10 2023-04-18 伊姆贝拉神经疗法公司 药物组合物及其用途
US10544974B2 (en) 2017-09-01 2020-01-28 Rebound Technologies, Inc. Solid production methods, systems, and devices
WO2020139953A1 (fr) 2018-12-26 2020-07-02 Rebound Technologies, Inc Systèmes, dispositifs et procédés de production de solides utilisant des surfaces oléophiles

Family Cites Families (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CH178013A (de) * 1934-12-17 1935-06-30 Escher Wyss Maschf Ag Verfahren und Anlage zur Erzeugung von Eis.
US2751762A (en) * 1952-08-08 1956-06-26 Proctor Drying And Freezing Co Method of freezing materials
GB764718A (en) * 1954-08-10 1957-01-02 Glaxo Lab Ltd Improvements in or relating to freeze-drying processes
DE1248863B (fr) * 1959-01-30
US3484946A (en) * 1967-12-06 1969-12-23 Bell Telephone Labor Inc Method and apparatus for freeze-freeze drying
US3655838A (en) * 1969-03-20 1972-04-11 Organon Method of pelletizing analytical or immunological reagents
FR2078585A5 (fr) * 1970-02-16 1971-11-05 Eastman Kodak Co
US3653222A (en) * 1970-02-27 1972-04-04 Bell Telephone Labor Inc Method of freezing solution droplets and the like using immiscible refrigerants of differing densities
US3721725A (en) * 1970-08-14 1973-03-20 Du Pont Process for preparing powder blends
US3959513A (en) * 1974-11-01 1976-05-25 The Kroger Company Method and system for producing a soft food product
JPS5840531B2 (ja) * 1975-09-05 1983-09-06 三共株式会社 抗コクシジウム剤
DE2634294C3 (de) * 1976-07-30 1979-01-25 Kraftwerk Union Ag, 4330 Muelheim Schutzeinrichtung für das Grundwasser im Bereich einer Kernreaktoranlage
GB1548022A (en) * 1976-10-06 1979-07-04 Wyeth John & Brother Ltd Pharmaceutial dosage forms
GB1594471A (en) * 1978-04-24 1981-07-30 Mason & Co Ltd Vaughan Production of beads from molten or thermoplastic material

Also Published As

Publication number Publication date
IE53538B1 (en) 1988-12-07
DK551282A (da) 1983-06-12
GR77845B (fr) 1984-09-25
PT75971A (en) 1983-01-01
IL67401A0 (en) 1983-05-15
US4470202A (en) 1984-09-11
IE822796L (en) 1983-06-11
KR880001208B1 (ko) 1988-07-11
EP0081913B1 (fr) 1985-06-26
ATE14047T1 (de) 1985-07-15
NZ202729A (en) 1985-08-16
ES8401610A1 (es) 1983-12-16
ES518081A0 (es) 1983-12-16
HU187197B (en) 1985-11-28
AU552072B2 (en) 1986-05-22
AR229378A1 (es) 1983-07-29
IL67401A (en) 1987-02-27
DK163448B (da) 1992-03-02
BR8207186A (pt) 1983-10-11
CA1197700A (fr) 1985-12-10
DE3264450D1 (en) 1985-08-01
KR840002653A (ko) 1984-07-16
EP0081913A1 (fr) 1983-06-22
PT75971B (en) 1985-02-27
JPS58104628A (ja) 1983-06-22
GB2111184B (en) 1985-03-13
GB2111184A (en) 1983-06-29
PH17895A (en) 1985-01-21
ZA828740B (en) 1984-07-25
JPH0243534B2 (fr) 1990-09-28
AU9096682A (en) 1983-06-16

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