DK162647C - Fremgangsmaade til fremstilling af pyrido-imidazorifamyciner - Google Patents

Fremgangsmaade til fremstilling af pyrido-imidazorifamyciner

Info

Publication number
DK162647C
DK162647C DK214685A DK214685A DK162647C DK 162647 C DK162647 C DK 162647C DK 214685 A DK214685 A DK 214685A DK 214685 A DK214685 A DK 214685A DK 162647 C DK162647 C DK 162647C
Authority
DK
Denmark
Prior art keywords
imidazorifamycines
procedure
preparing pyrido
pyrido
preparing
Prior art date
Application number
DK214685A
Other languages
Danish (da)
English (en)
Other versions
DK162647B (da
DK214685D0 (da
DK214685A (da
Inventor
Vincenzo Cannata
Gian Franco Tamagnone
Silvano Piani
Egidio Marchi
Original Assignee
Alfa Farmaceutici Spa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Alfa Farmaceutici Spa filed Critical Alfa Farmaceutici Spa
Publication of DK214685D0 publication Critical patent/DK214685D0/da
Publication of DK214685A publication Critical patent/DK214685A/da
Publication of DK162647B publication Critical patent/DK162647B/da
Application granted granted Critical
Publication of DK162647C publication Critical patent/DK162647C/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D498/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D498/22—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms in which the condensed system contains four or more hetero rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Communicable Diseases (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Oncology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
DK214685A 1984-05-15 1985-05-14 Fremgangsmaade til fremstilling af pyrido-imidazorifamyciner DK162647C (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
IT03463/84A IT1199374B (it) 1984-05-15 1984-05-15 Processo per la preparazione di pirido-imidazo-rifamicine
IT346384 1984-05-15

Publications (4)

Publication Number Publication Date
DK214685D0 DK214685D0 (da) 1985-05-14
DK214685A DK214685A (da) 1985-11-16
DK162647B DK162647B (da) 1991-11-25
DK162647C true DK162647C (da) 1992-04-13

Family

ID=11107845

Family Applications (1)

Application Number Title Priority Date Filing Date
DK214685A DK162647C (da) 1984-05-15 1985-05-14 Fremgangsmaade til fremstilling af pyrido-imidazorifamyciner

Country Status (18)

Country Link
US (1) US4557866A (enExample)
EP (1) EP0161534B1 (enExample)
JP (1) JPS60252483A (enExample)
AR (1) AR241913A1 (enExample)
AT (1) ATE46512T1 (enExample)
AU (1) AU568934B2 (enExample)
CA (1) CA1215708A (enExample)
DE (1) DE3573120D1 (enExample)
DK (1) DK162647C (enExample)
ES (1) ES8603489A1 (enExample)
FI (1) FI81101C (enExample)
GR (1) GR851144B (enExample)
IE (1) IE58392B1 (enExample)
IT (1) IT1199374B (enExample)
NO (1) NO164242C (enExample)
PH (1) PH22007A (enExample)
PT (1) PT80446B (enExample)
ZA (1) ZA852971B (enExample)

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US7906542B2 (en) 2004-11-04 2011-03-15 Alfa Wassermann, S.P.A. Pharmaceutical compositions comprising polymorphic forms α, β, and γ of rifaximin
ITMI20032144A1 (it) * 2003-11-07 2005-05-08 Alfa Wassermann Spa Forme polimorfe di rifaximina, processi per ottenerle e
US20080262024A1 (en) * 2003-11-07 2008-10-23 Giuseppe Claudio Viscomi Rifaximin compositions and method of use
US7923553B2 (en) 2003-11-07 2011-04-12 Alfa Wassermann, S.P.A. Processes for the production of polymorphic forms of rifaximin
US7902206B2 (en) 2003-11-07 2011-03-08 Alfa Wassermann, S.P.A. Polymorphic forms α, β and γ of rifaximin
US20060210483A1 (en) * 2005-03-02 2006-09-21 Kodsi Robert E Non-systemic antibiotic formulations and related method of use and treatment of upper respiratory infections
US8003118B2 (en) * 2005-03-02 2011-08-23 Kodsi Robert E Use of rifaximin for the prevention of aspiration pneumonia and/or sepsis
US20060210492A1 (en) * 2005-03-02 2006-09-21 Kodsi Robert E Use of rifaximin for treatment and prevention of periodontal conditions
ES2522895T3 (es) * 2005-03-03 2014-11-19 Alfa Wassermann S.P.A. Nuevas formas polimorfas de rifaximina, procedimientos para su producción y uso de las mismas en preparados medicinales
ITBO20050123A1 (it) 2005-03-07 2005-06-06 Alfa Wassermann Spa Formulazioni farmaceutiche gastroresistenti contenenti rifaximina
AU2007223881B2 (en) 2006-03-09 2014-01-09 Alan Safdi Rifaximin anti-rectal dysfunction preparation
WO2008016708A2 (en) 2006-08-02 2008-02-07 Salix Pharmaceuticals, Inc. Methods for treatment of radiation enteritis
ITMI20061692A1 (it) 2006-09-05 2008-03-06 Alfa Wassermann Spa Uso di polioli per ottenere forme polimorfe stabili di rifaximina
NZ575550A (en) * 2006-09-22 2011-12-22 Cipla Ltd Rifaximin
US20080159987A1 (en) * 2007-01-03 2008-07-03 Leonard Weinstock Use of Rifaximin for the Treatment of Restless Legs Syndrome
US20080161337A1 (en) * 2007-01-03 2008-07-03 Leonard Weinstock Use of Rifaximin for the Treatment of Chronic Prostatitis
ITMI20071241A1 (it) * 2007-06-20 2008-12-21 Solmag S P A Processo per la preparazione di rifaximina amorfa e rifaximina amorfa cosi' ottenuta
US7709634B2 (en) 2007-09-20 2010-05-04 Apotex Pharmachem Inc. Amorphous form of rifaximin and processes for its preparation
EA201370208A1 (ru) * 2008-02-25 2014-06-30 Сэликс Фармасьютиклз, Лтд. Формы рифаксимина и их применение
US8486956B2 (en) 2008-02-25 2013-07-16 Salix Pharmaceuticals, Ltd Forms of rifaximin and uses thereof
DK2252148T3 (da) 2008-02-26 2019-05-06 Salix Pharmaceuticals Ltd Fremgangsmåder til behandling af irritabel tarmsyndrom
US11779571B2 (en) 2008-02-26 2023-10-10 Salix Pharmaceuticals, Inc. Methods for treating irritable bowel syndrome (IBS)
ES2509892T3 (es) 2008-05-07 2014-10-20 Salix Pharmaceuticals, Ltd. Administración de un agente para limpieza del intestino y antibiótico para el tratamiento de enfermedad intestinal
CN101585843B (zh) * 2008-05-21 2011-07-06 重庆赛诺生物药业股份有限公司 一种利福昔明的制备工艺
US7928115B2 (en) 2008-10-02 2011-04-19 Salix Pharmaceuticals, Ltd. Methods of treating travelers diarrhea and hepatic encephalopathy
US12285414B2 (en) 2008-10-02 2025-04-29 Salix Pharmaceuticals, Inc. Methods of treating hepatic encephalopathy
US20110035232A1 (en) 2008-10-02 2011-02-10 Salix Pharmaceuticals, Ltd. Methods of treating hepatic encephalopathy
DK3628319T3 (da) 2008-10-02 2024-03-04 Salix Pharmaceuticals Ltd Behandling af hepatisk encefalopati ved anvendelse af rifaximin
AU2009326167A1 (en) 2008-12-10 2010-06-17 Cipla Limited Rifaximin complexes
IT1397617B1 (it) 2009-04-20 2013-01-18 Alfa Wassermann Spa Nuovi derivati della rifamicina
KR20170036116A (ko) 2009-06-02 2017-03-31 샐릭스 파마슈티컬스 리미티드 간성 뇌병증의 치료방법
EP2475392A4 (en) 2009-09-13 2013-01-09 Salix Pharmaceuticals Ltd METHOD FOR TREATING IRRITATION SYNDROME
AU2010320656B2 (en) 2009-11-23 2015-07-30 Cipla Limited Topical foam composition
WO2011080691A1 (en) 2009-12-28 2011-07-07 Silvio Massimo Lavagna Method for the production of amorphous rifaximin
WO2011103246A1 (en) 2010-02-18 2011-08-25 Salix Pharmaceuticals, Ltd. Methods for treating infection
IT1398550B1 (it) 2010-03-05 2013-03-01 Alfa Wassermann Spa Formulazioni comprendenti rifaximina utili per ottenere un effetto prolungato nel tempo
EP2582707A4 (en) * 2010-06-16 2014-01-08 Apotex Pharmachem Inc POLYMORPHIC FORMS OF RIFAXIMINE
JP5943915B2 (ja) 2010-07-12 2016-07-05 サリックス ファーマスーティカルズ，リミテッド リファキシミンの製剤およびその使用
WO2012035544A2 (en) 2010-09-13 2012-03-22 Sequent Scientific Ltd. A novel polymorphic form of rifaximin and process for its preparation
ES2682965T3 (es) 2011-02-11 2018-09-24 Salix Pharmaceuticals, Ltd. Formas de rifaximina y sus usos
EP2705042A1 (en) 2011-05-02 2014-03-12 Ranbaxy Laboratories Limited Rifaximin dimethylformamide solvate
WO2012155981A1 (en) 2011-05-19 2012-11-22 Friulchem Spa New process for the synthesis of rifaximin and a new pseudo-crystalline form of rifaximin obtained thereby
ITBO20110461A1 (it) 2011-07-29 2013-01-30 Alfa Wassermann Spa Composizioni farmaceutiche comprendenti rifaximina, processi per la loro preparazione e loro uso nel trattamento di infezioni vaginali.
PL2773205T3 (pl) 2011-11-02 2024-09-02 Salix Pharmaceuticals, Inc. Ryfaksymina w leczeniu ustępującej biegunki z przewagą zespołu jelita drażliwego
CA2876737A1 (en) 2012-06-13 2013-12-19 Apotex Pharmachem Inc. Polymorphic forms of rifaximin
ITBO20120368A1 (it) 2012-07-06 2014-01-07 Alfa Wassermann Spa Composizioni comprendenti rifaximina e amminoacidi, cristalli di rifaximina derivanti da tali composizioni e loro uso.
EA201591267A1 (ru) 2013-03-15 2016-03-31 Альфа Вассерманн С.П.А. Рифаксимин для применения в лечении вагинальных инфекций
US20160047819A1 (en) 2013-03-15 2016-02-18 Alfa Wassermann S.P.A. Method for diagnosing vaginal infections
EA032705B1 (ru) 2013-04-12 2019-07-31 Альфасигма С.П.А. Способ лечения или предупреждения энтеропатии
US9018225B1 (en) 2013-07-26 2015-04-28 Novel Laboratories Rifaximin crystalline forms and methods of preparation thereof
ITMI20131307A1 (it) 2013-08-02 2015-02-02 A M S A Anonima Materie Sint & Affini S P A Processo per la preparazione di refaximina k
CN103509038B (zh) * 2013-09-30 2016-01-20 浙江思贤制药有限公司 一种新晶型利福昔明ζ及其制备方法
ES2621557T3 (es) 2014-03-31 2017-07-04 Euticals S.P.A. Mezcla polimórfica de rifaximina y su uso para la preparación de formulaciones sólidas
CN106795192B (zh) 2014-05-04 2020-06-16 萨利克斯药品公司 Ibs微生物群及其用途
EP3546464B1 (en) 2014-05-12 2020-06-17 Alfasigma S.p.A. Preparation and use of crystalline form tau of rifaximin solvated with degme
EP2982764A1 (en) 2014-08-05 2016-02-10 ALFA WASSERMANN S.p.A. Identification of vaginal bacteria
US9988398B2 (en) 2016-06-07 2018-06-05 Cadila Healthcare Limited Crystalline form of rifaximin and process for its preparation
PT3518924T (pt) 2016-09-30 2022-10-27 Salix Pharmaceuticals Inc Formas de dispersão sólidas de rifaximina
WO2019003076A1 (en) * 2017-06-26 2019-01-03 Biofer S.P.A. PYRIDO-IMIDAZO-RIFAMYCIN DERIVATIVES AS ANTIBACTERIAL AGENT

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT1154655B (it) 1980-05-22 1987-01-21 Alfa Farmaceutici Spa Derivati imidazo-rifamicinici metodi per la loro preparazione e loro uso come sostanza ad azione antibatterica

Also Published As

Publication number Publication date
US4557866A (en) 1985-12-10
IE851191L (en) 1985-11-15
IT1199374B (it) 1988-12-30
FI851907A0 (fi) 1985-05-14
DK162647B (da) 1991-11-25
PT80446A (en) 1985-06-01
IE58392B1 (en) 1993-09-08
NO851921L (no) 1985-11-18
JPH0469634B2 (enExample) 1992-11-06
ZA852971B (en) 1985-12-24
EP0161534A2 (en) 1985-11-21
FI851907L (fi) 1985-11-16
ES543115A0 (es) 1986-01-01
ES8603489A1 (es) 1986-01-01
AR241913A1 (es) 1993-01-29
DE3573120D1 (en) 1989-10-26
NO164242C (no) 1990-09-12
FI81101B (fi) 1990-05-31
IT8403463A0 (it) 1984-05-15
FI81101C (fi) 1990-09-10
NO164242B (no) 1990-06-05
CA1215708A (en) 1986-12-23
EP0161534B1 (en) 1989-09-20
AU568934B2 (en) 1988-01-14
JPS60252483A (ja) 1985-12-13
PH22007A (en) 1988-05-02
DK214685D0 (da) 1985-05-14
DK214685A (da) 1985-11-16
EP0161534A3 (en) 1987-03-04
PT80446B (pt) 1987-11-11
AU4251585A (en) 1985-11-21
ATE46512T1 (de) 1989-10-15
GR851144B (enExample) 1985-11-25

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