DK162647C - Fremgangsmaade til fremstilling af pyrido-imidazorifamyciner - Google Patents

Fremgangsmaade til fremstilling af pyrido-imidazorifamyciner

Info

Publication number
DK162647C
DK162647C DK214685A DK214685A DK162647C DK 162647 C DK162647 C DK 162647C DK 214685 A DK214685 A DK 214685A DK 214685 A DK214685 A DK 214685A DK 162647 C DK162647 C DK 162647C
Authority
DK
Denmark
Prior art keywords
imidazorifamycines
procedure
preparing pyrido
pyrido
preparing
Prior art date
Application number
DK214685A
Other languages
Danish (da)
English (en)
Other versions
DK214685D0 (da
DK162647B (da
DK214685A (da
Inventor
Vincenzo Cannata
Gian Franco Tamagnone
Silvano Piani
Egidio Marchi
Original Assignee
Alfa Farmaceutici Spa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Alfa Farmaceutici Spa filed Critical Alfa Farmaceutici Spa
Publication of DK214685D0 publication Critical patent/DK214685D0/da
Publication of DK214685A publication Critical patent/DK214685A/da
Publication of DK162647B publication Critical patent/DK162647B/da
Application granted granted Critical
Publication of DK162647C publication Critical patent/DK162647C/da

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D498/00Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D498/22Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms in which the condensed system contains four or more hetero rings
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04Antibacterial agents

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Communicable Diseases (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Oncology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
DK214685A 1984-05-15 1985-05-14 Fremgangsmaade til fremstilling af pyrido-imidazorifamyciner DK162647C (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
IT03463/84A IT1199374B (it) 1984-05-15 1984-05-15 Processo per la preparazione di pirido-imidazo-rifamicine
IT346384 1984-05-15

Publications (4)

Publication Number Publication Date
DK214685D0 DK214685D0 (da) 1985-05-14
DK214685A DK214685A (da) 1985-11-16
DK162647B DK162647B (da) 1991-11-25
DK162647C true DK162647C (da) 1992-04-13

Family

ID=11107845

Family Applications (1)

Application Number Title Priority Date Filing Date
DK214685A DK162647C (da) 1984-05-15 1985-05-14 Fremgangsmaade til fremstilling af pyrido-imidazorifamyciner

Country Status (18)

Country Link
US (1) US4557866A (en, 2012)
EP (1) EP0161534B1 (en, 2012)
JP (1) JPS60252483A (en, 2012)
AR (1) AR241913A1 (en, 2012)
AT (1) ATE46512T1 (en, 2012)
AU (1) AU568934B2 (en, 2012)
CA (1) CA1215708A (en, 2012)
DE (1) DE3573120D1 (en, 2012)
DK (1) DK162647C (en, 2012)
ES (1) ES543115A0 (en, 2012)
FI (1) FI81101C (en, 2012)
GR (1) GR851144B (en, 2012)
IE (1) IE58392B1 (en, 2012)
IT (1) IT1199374B (en, 2012)
NO (1) NO164242C (en, 2012)
PH (1) PH22007A (en, 2012)
PT (1) PT80446B (en, 2012)
ZA (1) ZA852971B (en, 2012)

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US7923553B2 (en) 2003-11-07 2011-04-12 Alfa Wassermann, S.P.A. Processes for the production of polymorphic forms of rifaximin
ITMI20032144A1 (it) * 2003-11-07 2005-05-08 Alfa Wassermann Spa Forme polimorfe di rifaximina, processi per ottenerle e
US20080262024A1 (en) * 2003-11-07 2008-10-23 Giuseppe Claudio Viscomi Rifaximin compositions and method of use
US7902206B2 (en) 2003-11-07 2011-03-08 Alfa Wassermann, S.P.A. Polymorphic forms α, β and γ of rifaximin
US20060210483A1 (en) * 2005-03-02 2006-09-21 Kodsi Robert E Non-systemic antibiotic formulations and related method of use and treatment of upper respiratory infections
US20060210492A1 (en) * 2005-03-02 2006-09-21 Kodsi Robert E Use of rifaximin for treatment and prevention of periodontal conditions
US8003118B2 (en) * 2005-03-02 2011-08-23 Kodsi Robert E Use of rifaximin for the prevention of aspiration pneumonia and/or sepsis
EP1698630B1 (en) * 2005-03-03 2014-09-03 ALFA WASSERMANN S.p.A. New polymorphous forms of rifaximin, processes for their production and use thereof in the medicinal preparations
ITBO20050123A1 (it) 2005-03-07 2005-06-06 Alfa Wassermann Spa Formulazioni farmaceutiche gastroresistenti contenenti rifaximina
MX2008011305A (es) 2006-03-09 2009-02-10 Salix Pharmaceuticals Inc Preparacion anti-disfunsion rectal con rifaximina.
EP2054066B1 (en) 2006-08-02 2015-04-15 Salix Pharmaceuticals, Inc. Methods for treatment of radiation enteritis
ITMI20061692A1 (it) 2006-09-05 2008-03-06 Alfa Wassermann Spa Uso di polioli per ottenere forme polimorfe stabili di rifaximina
CA2663776C (en) * 2006-09-22 2016-01-26 Cipla Limited Rifaximin in an amorphous form
US20080161337A1 (en) * 2007-01-03 2008-07-03 Leonard Weinstock Use of Rifaximin for the Treatment of Chronic Prostatitis
US20080159987A1 (en) * 2007-01-03 2008-07-03 Leonard Weinstock Use of Rifaximin for the Treatment of Restless Legs Syndrome
ITMI20071241A1 (it) * 2007-06-20 2008-12-21 Solmag S P A Processo per la preparazione di rifaximina amorfa e rifaximina amorfa cosi' ottenuta
US7709634B2 (en) 2007-09-20 2010-05-04 Apotex Pharmachem Inc. Amorphous form of rifaximin and processes for its preparation
US8486956B2 (en) 2008-02-25 2013-07-16 Salix Pharmaceuticals, Ltd Forms of rifaximin and uses thereof
WO2009108730A2 (en) * 2008-02-25 2009-09-03 Salix Pharmaceuticals, Ltd. Forms of rifaximin and uses thereof
US11779571B2 (en) 2008-02-26 2023-10-10 Salix Pharmaceuticals, Inc. Methods for treating irritable bowel syndrome (IBS)
EP3563850A1 (en) 2008-02-26 2019-11-06 Salix Pharmaceuticals, Ltd. Methods for treating bowel diseases
CA2723752A1 (en) 2008-05-07 2009-11-12 Salix Pharmaceuticals, Ltd. Methods of treating bowel disease by administering a bowel cleanser and an antibiotic
CN101585843B (zh) * 2008-05-21 2011-07-06 重庆赛诺生物药业股份有限公司 一种利福昔明的制备工艺
LT3628319T (lt) 2008-10-02 2024-03-25 Salix Pharmaceuticals, Inc. Hepatinės encefalopatijos gydymas rifaksiminu
US12285414B2 (en) 2008-10-02 2025-04-29 Salix Pharmaceuticals, Inc. Methods of treating hepatic encephalopathy
US7928115B2 (en) * 2008-10-02 2011-04-19 Salix Pharmaceuticals, Ltd. Methods of treating travelers diarrhea and hepatic encephalopathy
US20110035232A1 (en) 2008-10-02 2011-02-10 Salix Pharmaceuticals, Ltd. Methods of treating hepatic encephalopathy
WO2010067072A1 (en) 2008-12-10 2010-06-17 Cipla Limited Rifaximin complexes
IT1397617B1 (it) * 2009-04-20 2013-01-18 Alfa Wassermann Spa Nuovi derivati della rifamicina
RU2540513C2 (ru) 2009-06-02 2015-02-10 Саликс Фармасьютикалз, Лтд. Способы лечения печеночной энцефалопатии
CN102596250A (zh) 2009-09-13 2012-07-18 萨利克斯药品有限公司 治疗肠易激综合征(ibs)的方法
NZ600362A (en) 2009-11-23 2014-08-29 Cipla Ltd Topical foam composition
US8952159B2 (en) 2009-12-28 2015-02-10 Silvio Massimo Lavagna Method for the production of amorphous rifaximin
AU2011218129A1 (en) 2010-02-18 2012-08-23 Board Of Regents Of The University Of Texas System Methods for treating infection
IT1398550B1 (it) 2010-03-05 2013-03-01 Alfa Wassermann Spa Formulazioni comprendenti rifaximina utili per ottenere un effetto prolungato nel tempo
CA2802874A1 (en) * 2010-06-16 2011-12-22 Apotex Pharmachem Inc. Polymorphic forms of rifaximin
EP3750526A1 (en) 2010-07-12 2020-12-16 Salix Pharmaceuticals, Inc. Formulations of rifaximin and uses thereof
WO2012035544A2 (en) 2010-09-13 2012-03-22 Sequent Scientific Ltd. A novel polymorphic form of rifaximin and process for its preparation
PH12013501643A1 (en) 2011-02-11 2019-10-11 Salix Pharmaceuticals Ltd Forms of rifaximin and uses thereof
EP2705042A1 (en) 2011-05-02 2014-03-12 Ranbaxy Laboratories Limited Rifaximin dimethylformamide solvate
WO2012155981A1 (en) 2011-05-19 2012-11-22 Friulchem Spa New process for the synthesis of rifaximin and a new pseudo-crystalline form of rifaximin obtained thereby
ITBO20110461A1 (it) 2011-07-29 2013-01-30 Alfa Wassermann Spa Composizioni farmaceutiche comprendenti rifaximina, processi per la loro preparazione e loro uso nel trattamento di infezioni vaginali.
PL2773205T3 (pl) 2011-11-02 2024-09-02 Salix Pharmaceuticals, Inc. Ryfaksymina w leczeniu ustępującej biegunki z przewagą zespołu jelita drażliwego
WO2013185211A1 (en) 2012-06-13 2013-12-19 Apotex Pharmachem Inc. Polymorphic forms of rifaximin
ITBO20120368A1 (it) 2012-07-06 2014-01-07 Alfa Wassermann Spa Composizioni comprendenti rifaximina e amminoacidi, cristalli di rifaximina derivanti da tali composizioni e loro uso.
US20160038468A1 (en) 2013-03-15 2016-02-11 Alfa Wassermann S.P.A. Rifaximin for use in the treating of vaginal infections
JP2016516988A (ja) 2013-03-15 2016-06-09 アルファ ワッセルマン ソシエタ ペル アチオニAlfa Wassermann S.P.A. 膣感染症を診断するための方法
PL2983647T3 (pl) 2013-04-12 2021-01-25 Alfasigma S.P.A. Podawanie nlpz oraz związane z tym składniki, sposoby i układy
US9018225B1 (en) 2013-07-26 2015-04-28 Novel Laboratories Rifaximin crystalline forms and methods of preparation thereof
ITMI20131307A1 (it) 2013-08-02 2015-02-02 A M S A Anonima Materie Sint & Affini S P A Processo per la preparazione di refaximina k
CN103509038B (zh) * 2013-09-30 2016-01-20 浙江思贤制药有限公司 一种新晶型利福昔明ζ及其制备方法
ES2621557T3 (es) 2014-03-31 2017-07-04 Euticals S.P.A. Mezcla polimórfica de rifaximina y su uso para la preparación de formulaciones sólidas
JP6693946B2 (ja) 2014-05-04 2020-05-13 サリックス ファーマスーティカルズ,インコーポレーテッド Ibs微生物叢及びその使用
KR102362719B1 (ko) 2014-05-12 2022-02-14 알파시그마 에스.피.에이. 리팍시민의 신규한 용매화 결정 형태, 생산물, 조성물 및 이의 용도
EP2982764A1 (en) 2014-08-05 2016-02-10 ALFA WASSERMANN S.p.A. Identification of vaginal bacteria
US9988398B2 (en) 2016-06-07 2018-06-05 Cadila Healthcare Limited Crystalline form of rifaximin and process for its preparation
KR20230023043A (ko) 2016-09-30 2023-02-16 샐릭스 파마슈티컬스 인코포레이티드 리팍시민의 고체 분산물 형태
ES2868180T3 (es) * 2017-06-26 2021-10-21 Biofer Spa Derivados de pirido-imidazo rifamicina como agentes antibacterianos

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT1154655B (it) 1980-05-22 1987-01-21 Alfa Farmaceutici Spa Derivati imidazo-rifamicinici metodi per la loro preparazione e loro uso come sostanza ad azione antibatterica

Also Published As

Publication number Publication date
DE3573120D1 (en) 1989-10-26
AR241913A1 (es) 1993-01-29
NO164242B (no) 1990-06-05
AU4251585A (en) 1985-11-21
NO164242C (no) 1990-09-12
DK214685D0 (da) 1985-05-14
ES8603489A1 (es) 1986-01-01
ZA852971B (en) 1985-12-24
PT80446A (en) 1985-06-01
DK162647B (da) 1991-11-25
IE58392B1 (en) 1993-09-08
AU568934B2 (en) 1988-01-14
FI81101B (fi) 1990-05-31
FI81101C (fi) 1990-09-10
DK214685A (da) 1985-11-16
IE851191L (en) 1985-11-15
JPH0469634B2 (en, 2012) 1992-11-06
FI851907L (fi) 1985-11-16
IT8403463A0 (it) 1984-05-15
FI851907A0 (fi) 1985-05-14
NO851921L (no) 1985-11-18
CA1215708A (en) 1986-12-23
PT80446B (pt) 1987-11-11
ES543115A0 (es) 1986-01-01
EP0161534B1 (en) 1989-09-20
EP0161534A3 (en) 1987-03-04
GR851144B (en, 2012) 1985-11-25
EP0161534A2 (en) 1985-11-21
ATE46512T1 (de) 1989-10-15
PH22007A (en) 1988-05-02
IT1199374B (it) 1988-12-30
JPS60252483A (ja) 1985-12-13
US4557866A (en) 1985-12-10

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