DK162640C - N-piperazinylalkanoylanilider og farmaceutiske kompositioner, der indeholder disse forbindelser - Google Patents

N-piperazinylalkanoylanilider og farmaceutiske kompositioner, der indeholder disse forbindelser

Info

Publication number
DK162640C
DK162640C DK048584A DK48584A DK162640C DK 162640 C DK162640 C DK 162640C DK 048584 A DK048584 A DK 048584A DK 48584 A DK48584 A DK 48584A DK 162640 C DK162640 C DK 162640C
Authority
DK
Denmark
Prior art keywords
piperazinylalkanoylanilides
compounds
pharmaceutical compositions
compositions containing
pharmaceutical
Prior art date
Application number
DK048584A
Other languages
Danish (da)
English (en)
Other versions
DK48584A (da
DK48584D0 (da
DK162640B (da
Inventor
Dante Nardi
Alberto Catto
Amedeo Leonardi
Gabriele Graziani
Original Assignee
Recordati Chem Pharm
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Recordati Chem Pharm filed Critical Recordati Chem Pharm
Publication of DK48584D0 publication Critical patent/DK48584D0/da
Publication of DK48584A publication Critical patent/DK48584A/da
Publication of DK162640B publication Critical patent/DK162640B/da
Application granted granted Critical
Publication of DK162640C publication Critical patent/DK162640C/da

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D295/00Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/04Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
    • C07D295/14Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C07D295/155Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals with the ring nitrogen atoms and the carbon atoms with three bonds to hetero atoms separated by carbocyclic rings or by carbon chains interrupted by carbocyclic rings
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D295/00Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/04Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
    • C07D295/14Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C07D295/145Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals with the ring nitrogen atoms and the carbon atoms with three bonds to hetero atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings
    • C07D295/15Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals with the ring nitrogen atoms and the carbon atoms with three bonds to hetero atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings to an acyclic saturated chain
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/12Antihypertensives
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D317/00Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms
    • C07D317/08Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3
    • C07D317/44Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D317/46Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 ortho- or peri-condensed with carbocyclic rings or ring systems condensed with one six-membered ring
    • C07D317/48Methylenedioxybenzenes or hydrogenated methylenedioxybenzenes, unsubstituted on the hetero ring
    • C07D317/62Methylenedioxybenzenes or hydrogenated methylenedioxybenzenes, unsubstituted on the hetero ring with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to atoms of the carbocyclic ring
    • C07D317/66Nitrogen atoms not forming part of a nitro radical

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Cardiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
DK048584A 1983-02-12 1984-02-03 N-piperazinylalkanoylanilider og farmaceutiske kompositioner, der indeholder disse forbindelser DK162640C (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB8303946 1983-02-12
GB838303946A GB8303946D0 (en) 1983-02-12 1983-02-12 Antihypertensive n-piperazinylalkanoylanilides

Publications (4)

Publication Number Publication Date
DK48584D0 DK48584D0 (da) 1984-02-03
DK48584A DK48584A (da) 1984-08-13
DK162640B DK162640B (da) 1991-11-25
DK162640C true DK162640C (da) 1992-04-13

Family

ID=10537908

Family Applications (1)

Application Number Title Priority Date Filing Date
DK048584A DK162640C (da) 1983-02-12 1984-02-03 N-piperazinylalkanoylanilider og farmaceutiske kompositioner, der indeholder disse forbindelser

Country Status (23)

Country Link
US (1) US4940711A (pl)
EP (1) EP0120558B1 (pl)
JP (1) JPS59152379A (pl)
KR (1) KR910000451B1 (pl)
AR (1) AR241182A1 (pl)
AT (1) ATE41150T1 (pl)
AU (1) AU565208B2 (pl)
CA (1) CA1254894A (pl)
DE (1) DE3476998D1 (pl)
DK (1) DK162640C (pl)
ES (1) ES8507529A1 (pl)
FI (1) FI80025C (pl)
GB (1) GB8303946D0 (pl)
GR (1) GR81460B (pl)
HU (1) HU191270B (pl)
IE (1) IE56652B1 (pl)
IL (1) IL70733A (pl)
MX (1) MX156049A (pl)
NZ (1) NZ206823A (pl)
PH (1) PH20244A (pl)
PT (1) PT78081B (pl)
SG (1) SG34889G (pl)
ZA (1) ZA84316B (pl)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB8303946D0 (en) * 1983-02-12 1983-03-16 Recordati Chem Pharm Antihypertensive n-piperazinylalkanoylanilides
JPS61134382A (ja) * 1984-12-04 1986-06-21 Kyorin Pharmaceut Co Ltd 新規なスルファモイル安息香酸誘導体およびその製造法
IT1190375B (it) * 1985-06-20 1988-02-16 Recordati Chem Pharm N-benzidrildiazacicloalchil-alcanilidi ad attivita' antianafilattica ed antibroncospastica
DE3642497A1 (de) * 1986-12-12 1988-06-23 Hoechst Ag Substituierte aminopropionsaeureamide, verfahren zu ihrer herstellung, diese enthaltende mittel und ihre verwendung sowie die bei der herstellung anfallenden neuen zwischenprodukte
JP2712222B2 (ja) * 1988-01-29 1998-02-10 三菱化学株式会社 抗不安薬
DK203990D0 (da) * 1990-08-24 1990-08-24 Novo Nordisk As Piperazinylderivater
US5474994A (en) * 1992-05-26 1995-12-12 Recordati S.A., Chemical And Pharmaceutical Company Bicyclic heterocyclic derivatives having α1 -adrenergic and 5HT1A
US5605896A (en) * 1992-02-25 1997-02-25 Recordati S.A., Chemical And Pharmaceutical Company Bicyclic heterocyclic derivatives having α1 adrenergic and 5HT1A activities
IT1254469B (it) * 1992-02-25 1995-09-25 Recordati Chem Pharm Derivati benzopiranici e benzotiopiranici
IT1258315B (it) * 1992-04-10 1996-02-22 Recordati Chem Pharm Derivati del flavone
US20160214967A1 (en) * 2013-09-30 2016-07-28 The University Of Tokyo Activator of adiponectin receptor
EP3193941B1 (en) * 2014-08-06 2024-05-22 Ascendis Pharma A/S Prodrugs comprising an aminoalkyl glycine linker
US20180305334A1 (en) * 2015-10-14 2018-10-25 Aquinnah Pharmaceuticals, Inc. Compounds, compositions and methods of use against stress granules

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB912788A (en) * 1959-11-16 1962-12-12 Miles Lab Phenylpiperazinylacyl anilines
DE1670200A1 (de) * 1967-03-22 1972-03-02 Byk Gulden Lomberg Chem Fab Neue arylsubstituierte Piperazinylcarbonsaeureanilide und Verfahren zu deren Herstellung
JPS5064282A (pl) * 1973-10-17 1975-05-31
JPS5849550B2 (ja) * 1974-02-07 1983-11-05 住友化学工業株式会社 シンキナアニリンユウドウタイ ノ セイホウ
GB1574019A (en) * 1977-01-14 1980-09-03 Joullie International Sa Therapeutically useful 3,4,5-trimethoxybenzene derivatives
US4202978A (en) * 1978-02-08 1980-05-13 Hoffmann-La Roche Inc. (S)-1-[2-(4-(2-Hydroxy-s-(1-alkylaminopropoxy)phenylalkyl]-4-phenylpiperazines
JPS58154573A (ja) * 1982-03-09 1983-09-14 Mitsubishi Chem Ind Ltd アルキレンジオキシベンゼン誘導体及びその酸付加塩
GB8303946D0 (en) * 1983-02-12 1983-03-16 Recordati Chem Pharm Antihypertensive n-piperazinylalkanoylanilides

Also Published As

Publication number Publication date
KR910000451B1 (en) 1991-01-25
GR81460B (pl) 1984-12-11
FI840478A (fi) 1984-08-13
DK48584A (da) 1984-08-13
DK48584D0 (da) 1984-02-03
HU191270B (en) 1987-01-28
IL70733A (en) 1987-10-30
EP0120558B1 (en) 1989-03-08
ES529642A0 (es) 1985-09-01
FI80025C (fi) 1990-04-10
JPS59152379A (ja) 1984-08-31
MX156049A (es) 1988-06-21
DK162640B (da) 1991-11-25
GB8303946D0 (en) 1983-03-16
AU2449484A (en) 1984-08-16
EP0120558A1 (en) 1984-10-03
PT78081B (en) 1986-04-17
CA1254894A (en) 1989-05-30
AR241182A1 (es) 1992-01-31
ZA84316B (en) 1985-02-27
NZ206823A (en) 1987-07-31
IE840207L (en) 1984-08-14
PT78081A (en) 1984-03-01
ATE41150T1 (de) 1989-03-15
SG34889G (en) 1989-10-13
US4940711A (en) 1990-07-10
ES8507529A1 (es) 1985-09-01
IL70733A0 (en) 1984-04-30
KR840007593A (ko) 1984-12-08
PH20244A (en) 1986-11-10
AU565208B2 (en) 1987-09-10
DE3476998D1 (de) 1989-04-13
IE56652B1 (en) 1991-10-23
JPH0434549B2 (pl) 1992-06-08
FI80025B (fi) 1989-12-29
FI840478A0 (fi) 1984-02-06

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