DK161091C - Svovlholdige antibiotiske forbindelser med antitumorvirkning, betegnet cl-1577a og cl-1577b, fremgangsmaade til fremstilling deraf, samt farmaceutiske praeparater indeholdende forbindelserne - Google Patents

Svovlholdige antibiotiske forbindelser med antitumorvirkning, betegnet cl-1577a og cl-1577b, fremgangsmaade til fremstilling deraf, samt farmaceutiske praeparater indeholdende forbindelserne

Info

Publication number
DK161091C
DK161091C DK294384A DK294384A DK161091C DK 161091 C DK161091 C DK 161091C DK 294384 A DK294384 A DK 294384A DK 294384 A DK294384 A DK 294384A DK 161091 C DK161091 C DK 161091C
Authority
DK
Denmark
Prior art keywords
compounds
antibiotic compounds
sulfable
antitumum
procedures
Prior art date
Application number
DK294384A
Other languages
Danish (da)
English (en)
Other versions
DK294384D0 (da
DK161091B (da
DK294384A (da
Inventor
Richard H Bunge
James C French
Timothy R Hurley
Tim A Smitka
Josefino B Tunac
Original Assignee
Warner Lambert Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Warner Lambert Co filed Critical Warner Lambert Co
Publication of DK294384D0 publication Critical patent/DK294384D0/da
Publication of DK294384A publication Critical patent/DK294384A/da
Publication of DK161091B publication Critical patent/DK161091B/da
Application granted granted Critical
Publication of DK161091C publication Critical patent/DK161091C/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P1/00—Preparation of compounds or compositions, not provided for in groups C12P3/00 - C12P39/00, by using microorganisms or enzymes
    • C12P1/06—Preparation of compounds or compositions, not provided for in groups C12P3/00 - C12P39/00, by using microorganisms or enzymes by using actinomycetales
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00—Microorganisms; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/20—Bacteria; Culture media therefor
    • C12N1/205—Bacterial isolates
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12R—INDEXING SCHEME ASSOCIATED WITH SUBCLASSES C12C - C12Q, RELATING TO MICROORGANISMS
    • C12R2001/00—Microorganisms ; Processes using microorganisms
    • C12R2001/01—Bacteria or Actinomycetales ; using bacteria or Actinomycetales
    • C12R2001/465—Streptomyces

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • General Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Biotechnology (AREA)
  • Genetics & Genomics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medicinal Chemistry (AREA)
  • Biochemistry (AREA)
  • Microbiology (AREA)
  • General Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Mycology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Virology (AREA)
  • Communicable Diseases (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Oncology (AREA)
  • Biomedical Technology (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Compounds Of Unknown Constitution (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Cephalosporin Compounds (AREA)
DK294384A 1983-07-08 1984-06-15 Svovlholdige antibiotiske forbindelser med antitumorvirkning, betegnet cl-1577a og cl-1577b, fremgangsmaade til fremstilling deraf, samt farmaceutiske praeparater indeholdende forbindelserne DK161091C (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US51208883 1983-07-08
US06/512,088 US4530835A (en) 1983-07-08 1983-07-08 CL-1577 Antibiotic compounds and their production

Publications (4)

Publication Number Publication Date
DK294384D0 DK294384D0 (da) 1984-06-15
DK294384A DK294384A (da) 1985-01-09
DK161091B DK161091B (da) 1991-05-27
DK161091C true DK161091C (da) 1991-11-11

Family

ID=24037622

Family Applications (1)

Application Number Title Priority Date Filing Date
DK294384A DK161091C (da) 1983-07-08 1984-06-15 Svovlholdige antibiotiske forbindelser med antitumorvirkning, betegnet cl-1577a og cl-1577b, fremgangsmaade til fremstilling deraf, samt farmaceutiske praeparater indeholdende forbindelserne

Country Status (12)

Country Link
US (1) US4530835A (enExample)
EP (1) EP0132082B1 (enExample)
JP (2) JPH0631279B2 (enExample)
AT (1) ATE46168T1 (enExample)
AU (1) AU565019B2 (enExample)
CA (1) CA1208148A (enExample)
DE (1) DE3479661D1 (enExample)
DK (1) DK161091C (enExample)
ES (1) ES534078A0 (enExample)
GR (1) GR82381B (enExample)
HK (1) HK77293A (enExample)
IE (1) IE57777B1 (enExample)

Families Citing this family (24)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4708872A (en) * 1983-05-16 1987-11-24 Bristol-Meyers Company Antitumor antibiotic complex
US4675187A (en) * 1983-05-16 1987-06-23 Bristol-Myers Company BBM-1675, a new antibiotic complex
US4868117A (en) * 1984-04-20 1989-09-19 Bristol-Myers Company BBM-1675, a new antitumor antibiotic complex
US4594248A (en) * 1985-03-15 1986-06-10 Warner-Lambert Company CL-1577-B4 compound, its production and use
IL79519A0 (en) * 1985-08-27 1986-10-31 Bristol Myers Co Bbm-1675c and d antitumor antibiotics
US5037651A (en) * 1987-01-30 1991-08-06 American Cyanamid Company Dihydro derivatives of LL-E33288 antibiotics
US4939244A (en) * 1987-01-30 1990-07-03 American Cyanamid Company Pseudoaglycones of LL-E33288 antibiotics
US4837206A (en) * 1987-04-29 1989-06-06 Bristol-Myers Company Esperamicin derivatives
JP2646707B2 (ja) * 1987-10-26 1997-08-27 藤沢薬品工業株式会社 新規化合物ｗｆ２０１５ａおよびｂ、それらの製造法ならびにそれらを含有する組成物
US5770701A (en) * 1987-10-30 1998-06-23 American Cyanamid Company Process for preparing targeted forms of methyltrithio antitumor agents
ES2059464T3 (es) * 1987-10-30 1994-11-16 American Cyanamid Co Formas especificamente dirigidas de agentes antitumorales de metiltritio.
US4996305A (en) * 1988-02-29 1991-02-26 American Cyanamid Company Process for producing the antibiotic and antitumor agents LL-E33288.epsilon.ε-Br
US4952572A (en) * 1988-06-10 1990-08-28 Bristol-Myers Company BU-3420T antifungal antibiotic
US4916065A (en) * 1988-06-10 1990-04-10 Bristol-Myers Company BU-3420T Antitumor antibiotic
OA09249A (fr) * 1988-12-19 1992-06-30 Lilly Co Eli Composés de macrolides.
US5086045A (en) * 1989-03-15 1992-02-04 Bristol-Myers Squibb Company Antitumor antibiotic
US5028536A (en) * 1989-03-15 1991-07-02 Bristol-Myers Squibb Company Antitumor antibiotic BMY-41339
US5116845A (en) * 1990-05-04 1992-05-26 Bristol-Myers Company BU-3420T antitumor antibiotic
US5227295A (en) * 1991-11-08 1993-07-13 Dowelanco Process for isolating A83543 and its components
DE69327247T2 (de) * 1992-09-09 2000-05-18 Nippon Kayaku K.K., Tokio/Tokyo Physiologisch aktive substanz nk175203, verfahren zu deren herstellung und pharmazeutische verwendung
US5591606A (en) * 1992-11-06 1997-01-07 Dowelanco Process for the production of A83543 compounds with Saccharopolyspora spinosa
JP4258575B2 (ja) * 1993-03-12 2009-04-30 ダウ・アグロサイエンス・エル・エル・シー 新規ａ８３５４３化合物及びそれらの製造法
US5712374A (en) * 1995-06-07 1998-01-27 American Cyanamid Company Method for the preparation of substantiallly monomeric calicheamicin derivative/carrier conjugates
US6001981A (en) * 1996-06-13 1999-12-14 Dow Agrosciences Llc Synthetic modification of Spinosyn compounds

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4578271A (en) * 1982-05-24 1986-03-25 Fujisawa Pharmaceutical Co., Ltd. Biologically active WS 6049 substances, a process for the production thereof and their pharmaceutical compositions

Also Published As

Publication number Publication date
AU2978184A (en) 1985-01-10
EP0132082A3 (en) 1985-10-23
JPH0678757A (ja) 1994-03-22
GR82381B (enExample) 1984-12-13
JPH0734740B2 (ja) 1995-04-19
IE841735L (en) 1985-01-08
DK294384D0 (da) 1984-06-15
ES8506095A1 (es) 1985-06-01
HK77293A (en) 1993-08-06
AU565019B2 (en) 1987-09-03
CA1208148A (en) 1986-07-22
ATE46168T1 (de) 1989-09-15
US4530835A (en) 1985-07-23
DK161091B (da) 1991-05-27
ES534078A0 (es) 1985-06-01
IE57777B1 (en) 1993-04-07
EP0132082B1 (en) 1989-09-06
EP0132082A2 (en) 1985-01-23
DK294384A (da) 1985-01-09
DE3479661D1 (en) 1989-10-12
JPS6041493A (ja) 1985-03-05
JPH0631279B2 (ja) 1994-04-27

Similar Documents

Publication Publication Date Title
DK294384D0 (da) Cl-1577 antibiotisk/antitumor virkende forbindelser samt fremgangsmaade til fremstilling deraf
UA19162A (uk) Спосіб одержаhhя аhтибіотика s541, штами стрептоміцетів - продуцеhти аhтибіотика s541
GB1496386A (en) Antibiotics
UA13320A (uk) Спосіб одержаhhя комплексhого аhтибіотика циклоспоріhу та/або його компоhеhтів та штам грибка tolypocladium varium
ES485074A1 (es) Un metodo de produccion de la mezcla antibiotica a-21978
SG49072A1 (en) A process for producing immunosuppressives and a novel microbial species to be employed therein
KR900003206A (ko) 항생물질 머사시딘, 이의 제조방법 및 약제로서의 이의 용도
DZ658A1 (fr) Antibiotiques produits par kibdelosporagium aridumet leur préparation.
ES548804A0 (es) Procedimiento para preparar antibioticos conteniendo azufre
GB1474129A (en) Method for the production of d-ribose
ES8700316A1 (es) Un procedimiento para la preparacion de compuesto denominado cl-1724b-2
ES463206A1 (es) Un metodo para preparar maytansinol, maytanacina o propiona-to de maytansinol.
ES382658A1 (es) Procedimiento de produccion de un nuevo antibiotico.
GB1500965A (en) Cyclic ether antibiotics
ES422433A1 (es) Un procedimiento para la produccion del antibiotico a-287.
EP0139457A3 (en) An antibiotic compound and its production
ES475179A1 (es) Un metodo mejorado para producir antibiotico c-15003 p-4.
EP0136923A3 (en) 2-amino-1,9-dihydro-6h-purin-6-one-7-oxide, the pharmaceutically acceptable salts and a process for the production thereof
YU48601B (sh) Postupak za dobijanje novog antibiotika balhimycina
BG44030A3 (en) Method for preparing of antibiotic a80190
BG40969A3 (bg) Метод за получаване на антибиотика сизомицин
ES485529A1 (es) Un procedimiento para la produccion de ravidomicina
ES8502729A1 (es) "un procedimiento para producir el complejo antibiotico m 9226"
DE3884741D1 (de) Mikrobiologisches Verfahren zur Herstellung von UK-61.689 und Mikroorganismen zur Verwendung darin.
IE841832L (en) ANTITUMOR AGENT FR 900216u