DE3479661D1 - Antibiotic/antitumor compounds and their production - Google Patents

Antibiotic/antitumor compounds and their production

Info

Publication number
DE3479661D1
DE3479661D1 DE8484304561T DE3479661T DE3479661D1 DE 3479661 D1 DE3479661 D1 DE 3479661D1 DE 8484304561 T DE8484304561 T DE 8484304561T DE 3479661 T DE3479661 T DE 3479661T DE 3479661 D1 DE3479661 D1 DE 3479661D1
Authority
DE
Germany
Prior art keywords
complex
antibiotic
compounds
antibiotic compounds
produced
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
DE8484304561T
Other languages
German (de)
English (en)
Inventor
Richard H Bunge
Timothy R Hurley
Josefino B Tunac
James C French
Tim A Smitka
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Warner Lambert Co LLC
Original Assignee
Warner Lambert Co LLC
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Warner Lambert Co LLC filed Critical Warner Lambert Co LLC
Application granted granted Critical
Publication of DE3479661D1 publication Critical patent/DE3479661D1/de
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P1/00—Preparation of compounds or compositions, not provided for in groups C12P3/00 - C12P39/00, by using microorganisms or enzymes
    • C12P1/06—Preparation of compounds or compositions, not provided for in groups C12P3/00 - C12P39/00, by using microorganisms or enzymes by using actinomycetales
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00—Microorganisms; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/20—Bacteria; Culture media therefor
    • C12N1/205—Bacterial isolates
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12R—INDEXING SCHEME ASSOCIATED WITH SUBCLASSES C12C - C12Q, RELATING TO MICROORGANISMS
    • C12R2001/00—Microorganisms ; Processes using microorganisms
    • C12R2001/01—Bacteria or Actinomycetales ; using bacteria or Actinomycetales
    • C12R2001/465—Streptomyces

Landscapes

  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • General Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Biotechnology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Mycology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Virology (AREA)
  • Communicable Diseases (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Oncology (AREA)
  • Biomedical Technology (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Compounds Of Unknown Constitution (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Cephalosporin Compounds (AREA)
DE8484304561T 1983-07-08 1984-07-04 Antibiotic/antitumor compounds and their production Expired DE3479661D1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US06/512,088 US4530835A (en) 1983-07-08 1983-07-08 CL-1577 Antibiotic compounds and their production

Publications (1)

Publication Number Publication Date
DE3479661D1 true DE3479661D1 (en) 1989-10-12

Family

ID=24037622

Family Applications (1)

Application Number Title Priority Date Filing Date
DE8484304561T Expired DE3479661D1 (en) 1983-07-08 1984-07-04 Antibiotic/antitumor compounds and their production

Country Status (12)

Country Link
US (1) US4530835A (enExample)
EP (1) EP0132082B1 (enExample)
JP (2) JPH0631279B2 (enExample)
AT (1) ATE46168T1 (enExample)
AU (1) AU565019B2 (enExample)
CA (1) CA1208148A (enExample)
DE (1) DE3479661D1 (enExample)
DK (1) DK161091C (enExample)
ES (1) ES534078A0 (enExample)
GR (1) GR82381B (enExample)
HK (1) HK77293A (enExample)
IE (1) IE57777B1 (enExample)

Families Citing this family (24)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4675187A (en) * 1983-05-16 1987-06-23 Bristol-Myers Company BBM-1675, a new antibiotic complex
US4708872A (en) * 1983-05-16 1987-11-24 Bristol-Meyers Company Antitumor antibiotic complex
US4868117A (en) * 1984-04-20 1989-09-19 Bristol-Myers Company BBM-1675, a new antitumor antibiotic complex
US4594248A (en) * 1985-03-15 1986-06-10 Warner-Lambert Company CL-1577-B4 compound, its production and use
IL79519A0 (en) * 1985-08-27 1986-10-31 Bristol Myers Co Bbm-1675c and d antitumor antibiotics
US4939244A (en) * 1987-01-30 1990-07-03 American Cyanamid Company Pseudoaglycones of LL-E33288 antibiotics
US5037651A (en) * 1987-01-30 1991-08-06 American Cyanamid Company Dihydro derivatives of LL-E33288 antibiotics
US4837206A (en) * 1987-04-29 1989-06-06 Bristol-Myers Company Esperamicin derivatives
JP2646707B2 (ja) * 1987-10-26 1997-08-27 藤沢薬品工業株式会社 新規化合物ｗｆ２０１５ａおよびｂ、それらの製造法ならびにそれらを含有する組成物
US5770701A (en) * 1987-10-30 1998-06-23 American Cyanamid Company Process for preparing targeted forms of methyltrithio antitumor agents
EP0313874B1 (en) * 1987-10-30 1994-04-13 American Cyanamid Company Disulfur analogs of LL-E33288 antitumor agents
US4996305A (en) * 1988-02-29 1991-02-26 American Cyanamid Company Process for producing the antibiotic and antitumor agents LL-E33288.epsilon.ε-Br
US4916065A (en) * 1988-06-10 1990-04-10 Bristol-Myers Company BU-3420T Antitumor antibiotic
US4952572A (en) * 1988-06-10 1990-08-28 Bristol-Myers Company BU-3420T antifungal antibiotic
MA21697A1 (fr) * 1988-12-19 1990-07-01 Dow Agrosciences Llc Composes de macrolides.
US5086045A (en) * 1989-03-15 1992-02-04 Bristol-Myers Squibb Company Antitumor antibiotic
US5028536A (en) * 1989-03-15 1991-07-02 Bristol-Myers Squibb Company Antitumor antibiotic BMY-41339
US5116845A (en) * 1990-05-04 1992-05-26 Bristol-Myers Company BU-3420T antitumor antibiotic
US5227295A (en) * 1991-11-08 1993-07-13 Dowelanco Process for isolating A83543 and its components
DE69327247T2 (de) * 1992-09-09 2000-05-18 Nippon Kayaku K.K., Tokio/Tokyo Physiologisch aktive substanz nk175203, verfahren zu deren herstellung und pharmazeutische verwendung
US5591606A (en) * 1992-11-06 1997-01-07 Dowelanco Process for the production of A83543 compounds with Saccharopolyspora spinosa
EP0688332B1 (en) * 1993-03-12 1997-03-26 Dowelanco New a83543 compounds and process for production thereof
US5712374A (en) * 1995-06-07 1998-01-27 American Cyanamid Company Method for the preparation of substantiallly monomeric calicheamicin derivative/carrier conjugates
US6001981A (en) * 1996-06-13 1999-12-14 Dow Agrosciences Llc Synthetic modification of Spinosyn compounds

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4578271A (en) * 1982-05-24 1986-03-25 Fujisawa Pharmaceutical Co., Ltd. Biologically active WS 6049 substances, a process for the production thereof and their pharmaceutical compositions

Also Published As

Publication number Publication date
DK294384D0 (da) 1984-06-15
ATE46168T1 (de) 1989-09-15
JPS6041493A (ja) 1985-03-05
JPH0678757A (ja) 1994-03-22
GR82381B (enExample) 1984-12-13
DK161091C (da) 1991-11-11
ES8506095A1 (es) 1985-06-01
DK161091B (da) 1991-05-27
ES534078A0 (es) 1985-06-01
EP0132082B1 (en) 1989-09-06
IE57777B1 (en) 1993-04-07
JPH0631279B2 (ja) 1994-04-27
HK77293A (en) 1993-08-06
DK294384A (da) 1985-01-09
JPH0734740B2 (ja) 1995-04-19
US4530835A (en) 1985-07-23
CA1208148A (en) 1986-07-22
EP0132082A3 (en) 1985-10-23
EP0132082A2 (en) 1985-01-23
AU2978184A (en) 1985-01-10
AU565019B2 (en) 1987-09-03
IE841735L (en) 1985-01-08

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee