DK294384A - Cl-1577 antibiotisk/antitumor virkende forbindelser samt fremgangsmaade til fremstilling deraf - Google Patents
Cl-1577 antibiotisk/antitumor virkende forbindelser samt fremgangsmaade til fremstilling deraf Download PDFInfo
- Publication number
- DK294384A DK294384A DK294384A DK294384A DK294384A DK 294384 A DK294384 A DK 294384A DK 294384 A DK294384 A DK 294384A DK 294384 A DK294384 A DK 294384A DK 294384 A DK294384 A DK 294384A
- Authority
- DK
- Denmark
- Prior art keywords
- antibiotic
- producing
- complex
- compounds
- procedures
- Prior art date
Links
- 150000001875 compounds Chemical class 0.000 title abstract 5
- 230000003115 biocidal effect Effects 0.000 title abstract 4
- 230000000259 anti-tumor effect Effects 0.000 title abstract 2
- 238000000034 method Methods 0.000 title 1
- IJGRMHOSHXDMSA-UHFFFAOYSA-N Atomic nitrogen Chemical compound N#N IJGRMHOSHXDMSA-UHFFFAOYSA-N 0.000 abstract 2
- 239000000039 congener Substances 0.000 abstract 2
- OKTJSMMVPCPJKN-UHFFFAOYSA-N Carbon Chemical compound [C] OKTJSMMVPCPJKN-UHFFFAOYSA-N 0.000 abstract 1
- NINIDFKCEFEMDL-UHFFFAOYSA-N Sulfur Chemical compound [S] NINIDFKCEFEMDL-UHFFFAOYSA-N 0.000 abstract 1
- 229910052799 carbon Inorganic materials 0.000 abstract 1
- 239000001963 growth medium Substances 0.000 abstract 1
- 229910052757 nitrogen Inorganic materials 0.000 abstract 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
- 239000000126 substance Substances 0.000 abstract 1
- 229910052717 sulfur Inorganic materials 0.000 abstract 1
- 239000011593 sulfur Substances 0.000 abstract 1
- 241001446247 uncultured actinomycete Species 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P1/00—Preparation of compounds or compositions, not provided for in groups C12P3/00 - C12P39/00, by using microorganisms or enzymes
- C12P1/06—Preparation of compounds or compositions, not provided for in groups C12P3/00 - C12P39/00, by using microorganisms or enzymes by using actinomycetales
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N1/00—Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
- C12N1/20—Bacteria; Culture media therefor
- C12N1/205—Bacterial isolates
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12R—INDEXING SCHEME ASSOCIATED WITH SUBCLASSES C12C - C12Q, RELATING TO MICROORGANISMS
- C12R2001/00—Microorganisms ; Processes using microorganisms
- C12R2001/01—Bacteria or Actinomycetales ; using bacteria or Actinomycetales
- C12R2001/465—Streptomyces
Landscapes
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Wood Science & Technology (AREA)
- Zoology (AREA)
- General Health & Medical Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Chemical & Material Sciences (AREA)
- Biotechnology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Genetics & Genomics (AREA)
- Medicinal Chemistry (AREA)
- Biochemistry (AREA)
- General Engineering & Computer Science (AREA)
- Microbiology (AREA)
- Pharmacology & Pharmacy (AREA)
- Mycology (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Virology (AREA)
- Communicable Diseases (AREA)
- Tropical Medicine & Parasitology (AREA)
- Oncology (AREA)
- Biomedical Technology (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Compounds Of Unknown Constitution (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Saccharide Compounds (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Cephalosporin Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US51208883 | 1983-07-08 | ||
| US06/512,088 US4530835A (en) | 1983-07-08 | 1983-07-08 | CL-1577 Antibiotic compounds and their production |
Publications (4)
| Publication Number | Publication Date |
|---|---|
| DK294384D0 DK294384D0 (da) | 1984-06-15 |
| DK294384A true DK294384A (da) | 1985-01-09 |
| DK161091B DK161091B (da) | 1991-05-27 |
| DK161091C DK161091C (da) | 1991-11-11 |
Family
ID=24037622
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK294384A DK161091C (da) | 1983-07-08 | 1984-06-15 | Svovlholdige antibiotiske forbindelser med antitumorvirkning, betegnet cl-1577a og cl-1577b, fremgangsmaade til fremstilling deraf, samt farmaceutiske praeparater indeholdende forbindelserne |
Country Status (12)
| Country | Link |
|---|---|
| US (1) | US4530835A (da) |
| EP (1) | EP0132082B1 (da) |
| JP (2) | JPH0631279B2 (da) |
| AT (1) | ATE46168T1 (da) |
| AU (1) | AU565019B2 (da) |
| CA (1) | CA1208148A (da) |
| DE (1) | DE3479661D1 (da) |
| DK (1) | DK161091C (da) |
| ES (1) | ES8506095A1 (da) |
| GR (1) | GR82381B (da) |
| HK (1) | HK77293A (da) |
| IE (1) | IE57777B1 (da) |
Families Citing this family (24)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4675187A (en) * | 1983-05-16 | 1987-06-23 | Bristol-Myers Company | BBM-1675, a new antibiotic complex |
| US4708872A (en) * | 1983-05-16 | 1987-11-24 | Bristol-Meyers Company | Antitumor antibiotic complex |
| US4868117A (en) * | 1984-04-20 | 1989-09-19 | Bristol-Myers Company | BBM-1675, a new antitumor antibiotic complex |
| US4594248A (en) * | 1985-03-15 | 1986-06-10 | Warner-Lambert Company | CL-1577-B4 compound, its production and use |
| IL79519A0 (en) * | 1985-08-27 | 1986-10-31 | Bristol Myers Co | Bbm-1675c and d antitumor antibiotics |
| US5037651A (en) * | 1987-01-30 | 1991-08-06 | American Cyanamid Company | Dihydro derivatives of LL-E33288 antibiotics |
| US4939244A (en) * | 1987-01-30 | 1990-07-03 | American Cyanamid Company | Pseudoaglycones of LL-E33288 antibiotics |
| US4837206A (en) * | 1987-04-29 | 1989-06-06 | Bristol-Myers Company | Esperamicin derivatives |
| JP2646707B2 (ja) * | 1987-10-26 | 1997-08-27 | 藤沢薬品工業株式会社 | 新規化合物ｗｆ２０１５ａおよびｂ、それらの製造法ならびにそれらを含有する組成物 |
| DE3851682T2 (de) * | 1987-10-30 | 1995-05-04 | American Cyanamid Co | Targetformer von Antitumor-Methyltrithioagenzien. |
| US5770701A (en) * | 1987-10-30 | 1998-06-23 | American Cyanamid Company | Process for preparing targeted forms of methyltrithio antitumor agents |
| US4996305A (en) * | 1988-02-29 | 1991-02-26 | American Cyanamid Company | Process for producing the antibiotic and antitumor agents LL-E33288.epsilon.ε-Br |
| US4916065A (en) * | 1988-06-10 | 1990-04-10 | Bristol-Myers Company | BU-3420T Antitumor antibiotic |
| US4952572A (en) * | 1988-06-10 | 1990-08-28 | Bristol-Myers Company | BU-3420T antifungal antibiotic |
| PE5591A1 (es) * | 1988-12-19 | 1991-02-15 | Lilly Co Eli | Un nuevo grupo de compuestos de macrolida |
| US5086045A (en) * | 1989-03-15 | 1992-02-04 | Bristol-Myers Squibb Company | Antitumor antibiotic |
| US5028536A (en) * | 1989-03-15 | 1991-07-02 | Bristol-Myers Squibb Company | Antitumor antibiotic BMY-41339 |
| US5116845A (en) * | 1990-05-04 | 1992-05-26 | Bristol-Myers Company | BU-3420T antitumor antibiotic |
| US5227295A (en) * | 1991-11-08 | 1993-07-13 | Dowelanco | Process for isolating A83543 and its components |
| EP0659759B1 (en) * | 1992-09-09 | 1999-12-08 | Nippon Kayaku Kabushiki Kaisha | Novel physiologically active substance nk175203, process for producing the same, and pharmaceutical use thereof |
| US5591606A (en) * | 1992-11-06 | 1997-01-07 | Dowelanco | Process for the production of A83543 compounds with Saccharopolyspora spinosa |
| WO1994020518A1 (en) * | 1993-03-12 | 1994-09-15 | Dowelanco | New a83543 compounds and process for production thereof |
| US5712374A (en) * | 1995-06-07 | 1998-01-27 | American Cyanamid Company | Method for the preparation of substantiallly monomeric calicheamicin derivative/carrier conjugates |
| US6001981A (en) * | 1996-06-13 | 1999-12-14 | Dow Agrosciences Llc | Synthetic modification of Spinosyn compounds |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4578271A (en) * | 1982-05-24 | 1986-03-25 | Fujisawa Pharmaceutical Co., Ltd. | Biologically active WS 6049 substances, a process for the production thereof and their pharmaceutical compositions |
-
1983
- 1983-07-08 US US06/512,088 patent/US4530835A/en not_active Expired - Lifetime
-
1984
- 1984-06-15 DK DK294384A patent/DK161091C/da active
- 1984-06-22 AU AU29781/84A patent/AU565019B2/en not_active Ceased
- 1984-07-03 CA CA000458000A patent/CA1208148A/en not_active Expired
- 1984-07-03 GR GR75173A patent/GR82381B/el unknown
- 1984-07-04 DE DE8484304561T patent/DE3479661D1/de not_active Expired
- 1984-07-04 AT AT84304561T patent/ATE46168T1/de not_active IP Right Cessation
- 1984-07-04 EP EP84304561A patent/EP0132082B1/en not_active Expired
- 1984-07-06 JP JP59139181A patent/JPH0631279B2/ja not_active Expired - Lifetime
- 1984-07-06 IE IE1735/84A patent/IE57777B1/en not_active IP Right Cessation
- 1984-07-06 ES ES534078A patent/ES8506095A1/es not_active Expired
-
1993
- 1993-06-28 JP JP5155968A patent/JPH0734740B2/ja not_active Expired - Lifetime
- 1993-07-29 HK HK772/93A patent/HK77293A/xx unknown
Also Published As
| Publication number | Publication date |
|---|---|
| HK77293A (en) | 1993-08-06 |
| CA1208148A (en) | 1986-07-22 |
| DE3479661D1 (en) | 1989-10-12 |
| US4530835A (en) | 1985-07-23 |
| ES534078A0 (es) | 1985-06-01 |
| GR82381B (da) | 1984-12-13 |
| ES8506095A1 (es) | 1985-06-01 |
| DK161091C (da) | 1991-11-11 |
| DK294384D0 (da) | 1984-06-15 |
| IE841735L (en) | 1985-01-08 |
| EP0132082B1 (en) | 1989-09-06 |
| JPH0734740B2 (ja) | 1995-04-19 |
| EP0132082A3 (en) | 1985-10-23 |
| JPH0678757A (ja) | 1994-03-22 |
| EP0132082A2 (en) | 1985-01-23 |
| JPS6041493A (ja) | 1985-03-05 |
| JPH0631279B2 (ja) | 1994-04-27 |
| ATE46168T1 (de) | 1989-09-15 |
| AU565019B2 (en) | 1987-09-03 |
| IE57777B1 (en) | 1993-04-07 |
| AU2978184A (en) | 1985-01-10 |
| DK161091B (da) | 1991-05-27 |
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