DK1564293T3 - Nervetrådproteingenekspression og detektion af Alzheimers sygdom - Google Patents
Nervetrådproteingenekspression og detektion af Alzheimers sygdomInfo
- Publication number
- DK1564293T3 DK1564293T3 DK04076254T DK04076254T DK1564293T3 DK 1564293 T3 DK1564293 T3 DK 1564293T3 DK 04076254 T DK04076254 T DK 04076254T DK 04076254 T DK04076254 T DK 04076254T DK 1564293 T3 DK1564293 T3 DK 1564293T3
- Authority
- DK
- Denmark
- Prior art keywords
- alzheimer
- disease
- detection
- gene expression
- protein gene
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
- C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
- C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
- C07K14/4701—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
- C07K14/4711—Alzheimer's disease; Amyloid plaque core protein
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
- C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
- C07K14/4701—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
- C07K14/474—Pancreatic thread protein; Reg protein
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
- G01N33/6893—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids related to diseases not provided for elsewhere
- G01N33/6896—Neurological disorders, e.g. Alzheimer's disease
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2600/00—Oligonucleotides characterized by their use
- C12Q2600/158—Expression markers
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2800/00—Detection or diagnosis of diseases
- G01N2800/28—Neurological disorders
- G01N2800/2814—Dementia; Cognitive disorders
- G01N2800/2821—Alzheimer
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Organic Chemistry (AREA)
- Biomedical Technology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Molecular Biology (AREA)
- General Health & Medical Sciences (AREA)
- Neurology (AREA)
- Medicinal Chemistry (AREA)
- Genetics & Genomics (AREA)
- Zoology (AREA)
- Biochemistry (AREA)
- Neurosurgery (AREA)
- Immunology (AREA)
- Biophysics (AREA)
- Analytical Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Hematology (AREA)
- Pathology (AREA)
- Wood Science & Technology (AREA)
- Microbiology (AREA)
- Biotechnology (AREA)
- Gastroenterology & Hepatology (AREA)
- Physics & Mathematics (AREA)
- Urology & Nephrology (AREA)
- Toxicology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Public Health (AREA)
- Food Science & Technology (AREA)
- Cell Biology (AREA)
- Hospice & Palliative Care (AREA)
- Psychiatry (AREA)
- General Engineering & Computer Science (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- General Physics & Mathematics (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US5055993A | 1993-04-20 | 1993-04-20 | |
| PCT/US1994/004321 WO1994023756A1 (en) | 1993-04-20 | 1994-04-20 | Neural thread protein gene expression and detection of alzheimer's disease |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DK1564293T3 true DK1564293T3 (da) | 2009-01-12 |
Family
ID=21965952
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK04076254T DK1564293T3 (da) | 1993-04-20 | 1994-04-20 | Nervetrådproteingenekspression og detektion af Alzheimers sygdom |
| DK94915396T DK0697893T3 (da) | 1993-04-20 | 1994-04-20 | Nervetrådproteingenekspression og detektion af Alzheimers sygdom |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK94915396T DK0697893T3 (da) | 1993-04-20 | 1994-04-20 | Nervetrådproteingenekspression og detektion af Alzheimers sygdom |
Country Status (11)
| Country | Link |
|---|---|
| EP (2) | EP0697893B1 (enExample) |
| JP (2) | JP3513859B2 (enExample) |
| KR (1) | KR100392244B1 (enExample) |
| AT (2) | ATE312348T1 (enExample) |
| CA (1) | CA2161097A1 (enExample) |
| DE (2) | DE69435136D1 (enExample) |
| DK (2) | DK1564293T3 (enExample) |
| ES (2) | ES2255054T3 (enExample) |
| NZ (1) | NZ266072A (enExample) |
| PT (1) | PT1564293E (enExample) |
| WO (1) | WO1994023756A1 (enExample) |
Families Citing this family (20)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5804560A (en) * | 1995-01-06 | 1998-09-08 | Sibia Neurosciences, Inc. | Peptide and peptide analog protease inhibitors |
| US5936078A (en) * | 1995-12-12 | 1999-08-10 | Kyowa Hakko Kogyo Co., Ltd. | DNA and protein for the diagnosis and treatment of Alzheimer's disease |
| EP0816492A1 (en) * | 1995-12-12 | 1998-01-07 | Kyowa Hakko Kogyo Co., Ltd. | Novel dnas, novel polypeptides and novel antibodies |
| US7226730B1 (en) | 1997-02-26 | 2007-06-05 | The General Hospital Corporation | Transgenic animals and cell lines for screening drugs effective for the treatment or prevention of Alzheimer's Disease |
| NZ337445A (en) | 1997-02-26 | 2000-12-22 | Gen Hospital Corp | Transgenic animals and cell lines for screening drugs effective for the treatment or prevention of alzheimer's disease |
| EP1006794B1 (en) | 1997-03-12 | 2007-11-28 | Robert W. Esmond | A method for treating or preventing alzheimer's disease |
| KR20040008177A (ko) * | 2001-05-16 | 2004-01-28 | 니목스 코포레이션 | 신경 사 단백질 세그먼트를 사용하여 세포 사멸을억제하는 방법 |
| EP1541166B1 (en) * | 2001-05-16 | 2007-12-19 | Nymox Corporation | Preventing cell death using segments of neural thread proteins |
| US6770797B2 (en) | 2001-06-01 | 2004-08-03 | Rhode Island Hospital | Non-Transgenic nonhuman model for Alzheimer's Disease using a AD7c-NTP nucleic acid |
| US7317077B2 (en) | 2001-11-16 | 2008-01-08 | Nymox Pharmaceutical Corporation | Peptides effective in the treatment of tumors and other conditions requiring the removal or destruction of cells |
| EP1714979A3 (en) * | 2001-11-16 | 2007-04-25 | Nymox Corporation | Peptides effective in the treatment of tumors and other conditions requiring the removal or destruction of cells |
| CN101389760A (zh) * | 2006-02-28 | 2009-03-18 | 尼莫克斯股份有限公司 | 有效治疗肿瘤或其他需要除去或破坏细胞的病症的肽 |
| US20080027005A1 (en) * | 2006-07-31 | 2008-01-31 | Paul Averback | Peptides effective in the treatment of tumors and other conditions requiring the removal or destruction of cells |
| US11628202B2 (en) | 2015-07-24 | 2023-04-18 | Nymox Corporation | Methods of reducing the need for surgery in patients suffering from benign prostatic hyperplasia |
| US10183058B2 (en) | 2016-06-17 | 2019-01-22 | Nymox Corporation | Method of preventing or reducing the progression of prostate cancer |
| US10172910B2 (en) | 2016-07-28 | 2019-01-08 | Nymox Corporation | Method of preventing or reducing the incidence of acute urinary retention |
| US10532081B2 (en) | 2016-09-07 | 2020-01-14 | Nymox Corporation | Method of ameliorating or preventing the worsening or the progression of symptoms of BPH |
| US10335453B2 (en) | 2017-03-01 | 2019-07-02 | Nymox Corporation | Compositions and methods for improving sexual function |
| CN119173632A (zh) * | 2022-05-10 | 2024-12-20 | 豪夫迈·罗氏有限公司 | 靶向cfp-elk1基因间区域的反义寡核苷酸 |
| EP4705767A1 (en) * | 2023-04-27 | 2026-03-11 | Siemens Healthcare Diagnostics Inc. | High-sensitivity assay for serum neurofilament light chain |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ES2094733T3 (es) * | 1988-12-21 | 1997-02-01 | Gen Hospital Corp | Deteccion de enfermedades o disfunciones neurologicas. |
-
1994
- 1994-04-20 DK DK04076254T patent/DK1564293T3/da active
- 1994-04-20 DK DK94915396T patent/DK0697893T3/da active
- 1994-04-20 ES ES94915396T patent/ES2255054T3/es not_active Expired - Lifetime
- 1994-04-20 NZ NZ266072A patent/NZ266072A/en not_active IP Right Cessation
- 1994-04-20 KR KR1019950704656A patent/KR100392244B1/ko not_active Expired - Fee Related
- 1994-04-20 AT AT94915396T patent/ATE312348T1/de not_active IP Right Cessation
- 1994-04-20 JP JP52355694A patent/JP3513859B2/ja not_active Expired - Fee Related
- 1994-04-20 ES ES04076254T patent/ES2312913T3/es not_active Expired - Lifetime
- 1994-04-20 DE DE69435136T patent/DE69435136D1/de not_active Expired - Fee Related
- 1994-04-20 CA CA002161097A patent/CA2161097A1/en not_active Abandoned
- 1994-04-20 PT PT04076254T patent/PT1564293E/pt unknown
- 1994-04-20 EP EP94915396A patent/EP0697893B1/en not_active Expired - Lifetime
- 1994-04-20 DE DE69434844T patent/DE69434844T2/de not_active Expired - Fee Related
- 1994-04-20 EP EP04076254A patent/EP1564293B9/en not_active Expired - Lifetime
- 1994-04-20 WO PCT/US1994/004321 patent/WO1994023756A1/en not_active Ceased
- 1994-04-20 AT AT04076254T patent/ATE406444T1/de not_active IP Right Cessation
-
2003
- 2003-10-01 JP JP2003343063A patent/JP2004097227A/ja active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| EP0697893B1 (en) | 2005-12-07 |
| JP3513859B2 (ja) | 2004-03-31 |
| ATE406444T1 (de) | 2008-09-15 |
| AU6666994A (en) | 1994-11-08 |
| EP1564293B9 (en) | 2009-08-19 |
| DE69434844D1 (de) | 2006-10-19 |
| DK0697893T3 (da) | 2006-02-20 |
| JPH08509808A (ja) | 1996-10-15 |
| EP0697893A4 (en) | 1996-12-18 |
| WO1994023756A1 (en) | 1994-10-27 |
| ES2312913T3 (es) | 2009-03-01 |
| ATE312348T1 (de) | 2005-12-15 |
| KR100392244B1 (ko) | 2003-11-28 |
| EP1564293B1 (en) | 2008-08-27 |
| CA2161097A1 (en) | 1994-10-27 |
| DE69434844T2 (de) | 2006-12-14 |
| ES2255054T3 (es) | 2006-06-16 |
| PT1564293E (pt) | 2008-12-02 |
| EP1564293A1 (en) | 2005-08-17 |
| NZ266072A (en) | 1997-07-27 |
| AU674581B2 (en) | 1997-01-02 |
| JP2004097227A (ja) | 2004-04-02 |
| DE69435136D1 (de) | 2008-10-09 |
| EP0697893A1 (en) | 1996-02-28 |
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