DE69735375D1 - Genfamilie von apoptose-verwandten peptiden, dadurch kodierte peptide und verfahren zu deren herstellung - Google Patents

Genfamilie von apoptose-verwandten peptiden, dadurch kodierte peptide und verfahren zu deren herstellung

Info

Publication number
DE69735375D1
DE69735375D1 DE69735375T DE69735375T DE69735375D1 DE 69735375 D1 DE69735375 D1 DE 69735375D1 DE 69735375 T DE69735375 T DE 69735375T DE 69735375 T DE69735375 T DE 69735375T DE 69735375 D1 DE69735375 D1 DE 69735375D1
Authority
DE
Germany
Prior art keywords
sarp
peptides
apoptosis
production
antibodies
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE69735375T
Other languages
English (en)
Other versions
DE69735375T2 (de
DE69735375T3 (de
Inventor
Samuil Umansky
Hovsep Melkonyan
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
GENTECH, INC., SAN FRANCISCO, CALIF., US
Original Assignee
Tanox Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=26701439&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=DE69735375(D1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Tanox Inc filed Critical Tanox Inc
Application granted granted Critical
Publication of DE69735375D1 publication Critical patent/DE69735375D1/de
Publication of DE69735375T2 publication Critical patent/DE69735375T2/de
Publication of DE69735375T3 publication Critical patent/DE69735375T3/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • C07K14/4701—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
    • C07K14/4747—Apoptosis related proteins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Toxicology (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Dermatology (AREA)
  • Peptides Or Proteins (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
DE69735375T 1996-09-24 1997-09-24 Genfamilie von apoptose-verwandten peptiden, dadurch kodierte peptide und verfahren zu deren herstellung Expired - Lifetime DE69735375T3 (de)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US2660396P 1996-09-24 1996-09-24
US26603P 1996-09-24
US2836396P 1996-10-11 1996-10-11
US28363P 1996-10-11
PCT/US1997/017154 WO1998013493A2 (en) 1996-09-24 1997-09-24 A family of genes encoding apoptosis-related peptides, peptides encoded thereby and methods of use thereof

Publications (3)

Publication Number Publication Date
DE69735375D1 true DE69735375D1 (de) 2006-04-27
DE69735375T2 DE69735375T2 (de) 2006-11-30
DE69735375T3 DE69735375T3 (de) 2010-09-02

Family

ID=26701439

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69735375T Expired - Lifetime DE69735375T3 (de) 1996-09-24 1997-09-24 Genfamilie von apoptose-verwandten peptiden, dadurch kodierte peptide und verfahren zu deren herstellung

Country Status (11)

Country Link
US (3) US6433155B1 (de)
EP (1) EP0932678B2 (de)
JP (2) JP4299886B2 (de)
AT (1) ATE318915T1 (de)
AU (1) AU737323B2 (de)
CA (1) CA2266325C (de)
DE (1) DE69735375T3 (de)
DK (1) DK0932678T4 (de)
ES (1) ES2263181T5 (de)
PT (1) PT932678E (de)
WO (1) WO1998013493A2 (de)

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US20070299005A1 (en) * 1996-09-24 2007-12-27 Tanox, Inc. Family of genes encoding apoptosis-related peptides, peptides encoded thereby and methods of use thereof
JP2001511010A (ja) * 1997-02-06 2001-08-07 ジェネティックス・インスチチュート・インコーポレーテッド ヒトｓｄｆ−５蛋白および組成物
CA2224473A1 (en) * 1997-05-21 1998-11-21 Smithkline Beecham Corporation A novel human gene similar to a secreted murine protein sdf5
EP0879885A1 (de) * 1997-05-23 1998-11-25 Smithkline Beecham Corporation GEN für ein sekretiertes-Maus-sFRP-1-Protein ähnliches Protein
AU7704498A (en) * 1997-05-29 1998-12-30 Government Of The United States Of America, As Represented By The Secretary Of The Department Of Health And Human Services, The Human frp and fragments thereof including methods for using them
US20030203446A1 (en) * 1998-10-07 2003-10-30 Genentech, Inc. Secreted and transmembrane polypeptides and nucleic acids encoding the same
CN1413257A (zh) * 1998-10-30 2003-04-23 内布拉斯加大学林肯分校 细胞凋亡基因的跨种转移和由此产生的转基因植物
GB9921009D0 (en) * 1999-09-07 1999-11-10 Neuropa Ltd Essential genes and assays relating thereto
US20080166356A9 (en) * 1999-09-13 2008-07-10 Peter Bodine Pharmaceutical compositions and methods of using secreted frizzled related protein
US6600018B1 (en) 2000-04-10 2003-07-29 The United States Of America As Represented By The Department Of Health And Human Services Secreted frizzled related protein, sFRP, fragments and methods of use thereof
YU45103A (sh) 2000-12-06 2006-08-17 Applied Research Systems Ars Holding N.V. Upotreba sarp/1 za lečenje i prevenciju skleroderme
US7488710B2 (en) 2001-01-10 2009-02-10 The United States Of America As Represented By The Department Of Health And Human Services SFRP and peptide motifs that interact with SFRP and methods of their use
EP1222933A1 (de) * 2001-01-15 2002-07-17 Academisch Ziekenhuis Leiden h.o.d.n., Leids Universitair Medisch Centrum Bildung und/oder Reduktion von neuem Lungengewebe in einer erkranketen Lunge, durch Modulierung des Wnt-Signalwegs
US20030044409A1 (en) * 2001-05-01 2003-03-06 Carson Dennis A. Immunologic compositions and methods for studying and treating cancers expressing frizzled antigens
US7682607B2 (en) * 2001-05-01 2010-03-23 The Regents Of The University Of California Wnt and frizzled receptors as targets for immunotherapy in head and neck squamous cell carcinomas
US7879544B2 (en) * 2002-07-29 2011-02-01 Hmgene Inc. Methods of identifying adipocyte specific genes, the genes identified, and their uses
US20050054599A1 (en) * 2003-05-02 2005-03-10 Coles John G. Biosynthetic platform for cardioprotective stress response in human fetal heart tissue
WO2005061536A1 (en) * 2003-12-16 2005-07-07 Aventis Pharmaceuticals Inc. Secreted neural apoptosis inhibiting proteins
DK2444505T3 (da) 2004-07-23 2017-01-02 Pacific Edge Ltd Urinmarkører til påvisning af blærecancer
DE602006019974D1 (de) 2005-08-19 2011-03-17 Univ Duke Aus stammzellen erhaltener parakriner faktor h12 zur verwendung für die verringerung zelltodes oder für die reparatur von gewebe
WO2007053577A2 (en) * 2005-10-31 2007-05-10 Oncomed Pharmaceuticals, Inc. Compositions and methods for diagnosing and treating cancer
US7723477B2 (en) 2005-10-31 2010-05-25 Oncomed Pharmaceuticals, Inc. Compositions and methods for inhibiting Wnt-dependent solid tumor cell growth
NZ545243A (en) * 2006-02-10 2009-07-31 Pacific Edge Biotechnology Ltd Urine gene expression ratios for detection of cancer
MX2009002522A (es) * 2006-09-08 2009-06-19 Genentech Inc Antagonistas de wnt y su uso en el diagnóstico y tratamiento de trastornos mediados por wnt.
JP5792621B2 (ja) 2008-09-26 2015-10-14 オンコメッド ファーマシューティカルズ インコーポレイテッド ｆｒｉｚｚｌｅｄ結合剤およびその使用
TWI535445B (zh) 2010-01-12 2016-06-01 安可美德藥物股份有限公司 Ｗｎｔ拮抗劑及治療和篩選方法
MX347515B (es) 2010-04-01 2017-04-28 Oncomed Pharmaceuticals Inc * Agentes que se unen al receptor encrespado y usos de los mismos.
EP2600901B1 (de) 2010-08-06 2019-03-27 ModernaTX, Inc. Pharmazeutische zusammensetzungen enthaltenbearbeitete nukleinsäuren und ihre medizinische verwendung
HRP20220796T1 (hr) 2010-10-01 2022-10-14 ModernaTX, Inc. Ribonukleinske kiseline koje sadrže n1-metil-pseudouracil i njihove uporabe
CA2831613A1 (en) 2011-03-31 2012-10-04 Moderna Therapeutics, Inc. Delivery and formulation of engineered nucleic acids
US9464124B2 (en) 2011-09-12 2016-10-11 Moderna Therapeutics, Inc. Engineered nucleic acids and methods of use thereof
EP3492109B1 (de) 2011-10-03 2020-03-04 ModernaTX, Inc. Modifizierte nukleoside, nukleotide und nukleinsäuren und verwendungen davon
RS63244B1 (sr) 2011-12-16 2022-06-30 Modernatx Inc Kompozicije modifikovane mrna
US9303079B2 (en) 2012-04-02 2016-04-05 Moderna Therapeutics, Inc. Modified polynucleotides for the production of cytoplasmic and cytoskeletal proteins
US9283287B2 (en) 2012-04-02 2016-03-15 Moderna Therapeutics, Inc. Modified polynucleotides for the production of nuclear proteins
WO2013151664A1 (en) 2012-04-02 2013-10-10 modeRNA Therapeutics Modified polynucleotides for the production of proteins
US9572897B2 (en) 2012-04-02 2017-02-21 Modernatx, Inc. Modified polynucleotides for the production of cytoplasmic and cytoskeletal proteins
EP2911691B1 (de) 2012-10-23 2018-10-10 OncoMed Pharmaceuticals, Inc. Verfahren zur behandlung von neuroendokrinen tumoren mit wnt-pad-bindemitteln
PL2922554T3 (pl) 2012-11-26 2022-06-20 Modernatx, Inc. Na zmodyfikowany na końcach
WO2014121196A1 (en) 2013-02-04 2014-08-07 Oncomed Pharmaceuticals, Inc. Methods and monitoring of treatment with a wnt pathway inhibitor
US9168300B2 (en) 2013-03-14 2015-10-27 Oncomed Pharmaceuticals, Inc. MET-binding agents and uses thereof
US8980864B2 (en) 2013-03-15 2015-03-17 Moderna Therapeutics, Inc. Compositions and methods of altering cholesterol levels
EP3052106A4 (de) 2013-09-30 2017-07-19 ModernaTX, Inc. Polynukleotide zur codierung immunmodulierender polypeptide
SG11201602503TA (en) 2013-10-03 2016-04-28 Moderna Therapeutics Inc Polynucleotides encoding low density lipoprotein receptor

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NL154598B (nl) 1970-11-10 1977-09-15 Organon Nv Werkwijze voor het aantonen en bepalen van laagmoleculire verbindingen en van eiwitten die deze verbindingen specifiek kunnen binden, alsmede testverpakking.
US3817837A (en) 1971-05-14 1974-06-18 Syva Corp Enzyme amplification assay
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US4277437A (en) 1978-04-05 1981-07-07 Syva Company Kit for carrying out chemically induced fluorescence immunoassay
US4275149A (en) 1978-11-24 1981-06-23 Syva Company Macromolecular environment control in specific receptor assays
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US5639856A (en) * 1993-09-13 1997-06-17 The Regents Of The University Of California Semaphorin gene family
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US5672686A (en) 1994-08-09 1997-09-30 Immunogen, Inc. Bcl-Y - specific antibodies

Also Published As

Publication number Publication date
WO1998013493A2 (en) 1998-04-02
ES2263181T3 (es) 2006-12-01
US20030023061A1 (en) 2003-01-30
CA2266325C (en) 2012-07-17
WO1998013493A3 (en) 1998-06-04
US6433155B1 (en) 2002-08-13
US7045596B2 (en) 2006-05-16
US7045604B2 (en) 2006-05-16
EP0932678A2 (de) 1999-08-04
AU4651397A (en) 1998-04-17
DE69735375T2 (de) 2006-11-30
JP4299886B2 (ja) 2009-07-22
AU737323B2 (en) 2001-08-16
DK0932678T3 (da) 2006-05-22
DE69735375T3 (de) 2010-09-02
DK0932678T4 (da) 2010-07-12
JP2002516564A (ja) 2002-06-04
ATE318915T1 (de) 2006-03-15
PT932678E (pt) 2006-07-31
ES2263181T5 (es) 2011-04-07
JP2009050257A (ja) 2009-03-12
EP0932678B1 (de) 2006-03-01
EP0932678B2 (de) 2010-03-10
US20040039184A1 (en) 2004-02-26
CA2266325A1 (en) 1998-04-02

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Legal Events

Date Code Title Description
8363 Opposition against the patent
8366 Restricted maintained after opposition proceedings
8327 Change in the person/name/address of the patent owner

Owner name: GENTECH, INC., SAN FRANCISCO, CALIF., US