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20 human secreted proteins

Info

Publication number
WO1998045712A3
WO1998045712A3 PCT/US1998/006801 US9806801W WO1998045712A3 WO 1998045712 A3 WO1998045712 A3 WO 1998045712A3 US 9806801 W US9806801 W US 9806801W WO 1998045712 A3 WO1998045712 A3 WO 1998045712A3
Authority
WO
Grant status
Application
Patent type
Prior art keywords
proteins
human
secreted
invention
methods
Prior art date
Application number
PCT/US1998/006801
Other languages
French (fr)
Other versions
WO1998045712A2 (en )
Inventor
Craig A Rosen
Steven M Ruben
Guo-Liang Yu
Jian Ni
Ping Feng
Original Assignee
Human Genome Sciences Inc
Craig A Rosen
Steven M Ruben
Yu Guo Liang
Jian Ni
Ping Feng
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
    • A61K48/00Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2319/00Fusion polypeptide
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2319/00Fusion polypeptide
    • C07K2319/01Fusion polypeptide containing a localisation/targetting motif
    • C07K2319/02Fusion polypeptide containing a localisation/targetting motif containing a signal sequence
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2799/00Uses of viruses
    • C12N2799/02Uses of viruses as vector
    • C12N2799/021Uses of viruses as vector for the expression of a heterologous nucleic acid
    • C12N2799/026Uses of viruses as vector for the expression of a heterologous nucleic acid where the vector is derived from a baculovirus

Abstract

The present invention relates to 20 human secreted proteins and isolated nucleic acids containing the coding regions of the genes encoding such proteins. Also provided are vectors, host cells, antibodies, and recombinant methods for producing human secreted proteins. The invention further relates to diagnostic and therapeutic methods useful for diagnosing and treating disorders related to these human secreted proteins.
PCT/US1998/006801 1997-04-08 1998-04-07 20 human secreted proteins WO1998045712A3 (en)

Priority Applications (16)

Application Number Priority Date Filing Date Title
US4272697 true 1997-04-08 1997-04-08
US4275497 true 1997-04-08 1997-04-08
US4272897 true 1997-04-08 1997-04-08
US4272797 true 1997-04-08 1997-04-08
US4282597 true 1997-04-08 1997-04-08
US4818497 true 1997-05-30 1997-05-30
US4806897 true 1997-05-30 1997-05-30
US4807097 true 1997-05-30 1997-05-30
US60/048,184 1997-05-30
US60/048,070 1997-05-30
US60/042,728 1997-05-30
US60/042,726 1997-05-30
US60/048,068 1997-05-30
US60/042,825 1997-05-30
US60/042,754 1997-05-30
US60/042,727 1997-05-30

Applications Claiming Priority (15)

Application Number Priority Date Filing Date Title
CA 2286303 CA2286303A1 (en) 1997-04-08 1998-04-07 20 human secreted proteins
EP19980915313 EP0974058A2 (en) 1997-04-08 1998-04-07 20 human secreted proteins
JP54300598A JP2001521383A (en) 1997-04-08 1998-04-07 20 human secreted proteins
US09814122 US20020058307A1 (en) 1997-04-08 2001-03-22 20 Human secreted proteins
US10100683 US7368531B2 (en) 1997-03-07 2002-03-19 Human secreted proteins
US10649857 US20040063128A1 (en) 1997-04-08 2003-08-28 20 Human secreted proteins
US10664357 US20070055056A1 (en) 1997-03-07 2003-09-20 251 human secreted proteins
US10664356 US20070015696A1 (en) 1997-03-07 2003-09-20 621 human secreted proteins
US11001793 US7411051B2 (en) 1997-03-07 2004-12-02 Antibodies to HDPPA04 polypeptide
US11346470 US20060223088A1 (en) 1997-03-07 2006-02-03 Human secreted proteins
US11366980 US20060223090A1 (en) 1997-03-07 2006-03-03 Polynucleotides encoding human secreted proteins
US11366486 US20060246483A1 (en) 1997-03-07 2006-03-03 337 human secreted proteins
US11687755 US20080103090A1 (en) 1997-03-07 2007-03-19 Human Secreted Proteins
US11689173 US20070224663A1 (en) 1997-03-07 2007-03-21 Human Secreted Proteins
US12198817 US7968689B2 (en) 1997-03-07 2008-08-26 Antibodies to HSDEK49 polypeptides

Related Parent Applications (2)

Application Number Title Priority Date Filing Date
PCT/US1998/005311 Continuation-In-Part WO1998042738A1 (en) 1997-03-21 1998-03-19 87 human secreted proteins
PCT/US1998/010868 Continuation-In-Part WO1998054206A1 (en) 1997-05-30 1998-05-28 32 human secreted proteins

Related Child Applications (3)

Application Number Title Priority Date Filing Date
PCT/US1998/011422 Continuation-In-Part WO1998054963A2 (en) 1997-06-06 1998-06-04 207 human secreted proteins
US16678098 Continuation-In-Part 1998-10-06 1998-10-06
US10100683 Continuation-In-Part US7368531B2 (en) 1997-03-07 2002-03-19 Human secreted proteins

Publications (2)

Publication Number Publication Date
WO1998045712A2 true WO1998045712A2 (en) 1998-10-15
WO1998045712A3 true true WO1998045712A3 (en) 1998-12-03

Family

ID=27574292

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US1998/006801 WO1998045712A3 (en) 1997-04-08 1998-04-07 20 human secreted proteins

Country Status (4)

Country Link
JP (1) JP2001521383A (en)
CA (1) CA2286303A1 (en)
EP (1) EP0974058A2 (en)
WO (1) WO1998045712A3 (en)

Families Citing this family (25)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7291712B2 (en) * 1998-06-25 2007-11-06 Genentech, Inc. Interleukin-8 homologous polypeptides and therapeutic uses thereof
JP2001519156A (en) * 1997-10-02 2001-10-23 ヒューマン ジノーム サイエンシーズ, インコーポレイテッド 101 pieces of human secreted proteins
EP1445316A1 (en) * 1997-10-02 2004-08-11 Human Genome Sciences, Inc. Novel secreted protein
EP1111046A4 (en) * 1998-09-03 2003-07-02 Takeda Chemical Industries Ltd Novel protein and process for producing the same
EP1159284A4 (en) * 1999-02-10 2003-10-29 Human Genome Sciences Inc 33 human secreted proteins
WO2000055175A1 (en) * 1999-03-12 2000-09-21 Human Genome Sciences, Inc. 50 human secreted proteins
JP2004506402A (en) * 1999-03-23 2004-03-04 ヒューマン ジノーム サイエンシーズ, インコーポレイテッドHuman Genome Sciences, Inc. 48 human secreted proteins
EP1171626A4 (en) * 1999-03-26 2002-10-30 Human Genome Sciences Inc 50 human secreted proteins
JP2002539816A (en) * 1999-03-26 2002-11-26 ヒューマン ジノーム サイエンシーズ, インコーポレイテッド 50 pieces of human secreted proteins
CA2368482A1 (en) * 1999-03-26 2000-10-05 Craig A. Rosen 50 human secreted proteins
JP2002543772A (en) * 1999-04-09 2002-12-24 ヒューマン ジノーム サイエンシーズ, インコーポレイテッド 49 pieces of human secreted proteins
EP1179064A2 (en) * 1999-05-14 2002-02-13 Curagen Corporation Secreted polypeptides and corresponding polynucleotides
JP2003521885A (en) * 1999-06-23 2003-07-22 キュラジェン コーポレイション Polynucleotides and polypeptides encoded by them
WO2001005971A9 (en) * 1999-07-20 2001-10-18 Curagen Corp Secreted polypeptides and corresponding polynucleotides
US7001766B2 (en) 1999-07-20 2006-02-21 Curagen Corporation Nucleic acid sequences encoding human angiopoietin-like polypeptides
CA2381396A1 (en) * 1999-08-11 2001-02-15 Curagen Corporation Polynucleotides and polypeptides encoded thereby
EP1212343A4 (en) * 1999-09-03 2004-11-03 Human Genome Sciences Inc 52 human secreted proteins
CA2384749A1 (en) * 1999-09-13 2001-03-22 Curagen Corporation Novel human proteins, polynucleotides encoding them and methods of using the same
JP4620920B2 (en) 1999-11-02 2011-01-26 デーエルカー ブルーツペンデディーンスト バーデン−ヴュルテンベルク−ヘッセン ゲーゲーエムベーハー Rhd negative locus of the molecular structure
EP1246918A2 (en) * 2000-01-14 2002-10-09 Incyte Genomics, Inc. Secreted proteins
WO2001062927A3 (en) * 2000-02-24 2002-04-25 Incyte Genomics, Inc. Polypeptides and corresponding polynucleotides for diagnostics and therapeutics
US20050095587A1 (en) * 2000-02-24 2005-05-05 Panzer Scott R. Molecules for disease detection and treatment
EP1263949A2 (en) * 2000-02-24 2002-12-11 Incyte Genomics, Inc. Secretory polypeptides and corresponding polynucleotides
EP1368375A2 (en) * 2000-09-05 2003-12-10 Incyte Genomics, Inc. Secretory molecules
EP1364015A2 (en) * 2000-09-05 2003-11-26 Incyte Genomics, Inc. Molecules for diagnostics and therapeutics

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5536637A (en) * 1993-04-07 1996-07-16 Genetics Institute, Inc. Method of screening for cDNA encoding novel secreted mammalian proteins in yeast
WO1997007198A2 (en) * 1995-08-11 1997-02-27 Genetics Institute, Inc. Dna sequences and secreted proteins encoded thereby

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5536637A (en) * 1993-04-07 1996-07-16 Genetics Institute, Inc. Method of screening for cDNA encoding novel secreted mammalian proteins in yeast
WO1997007198A2 (en) * 1995-08-11 1997-02-27 Genetics Institute, Inc. Dna sequences and secreted proteins encoded thereby

Non-Patent Citations (3)

* Cited by examiner, † Cited by third party
Title
Database EMBL, entry EMEST8:HS898325, Accession number N94898 19 April 1996 88% identity with Seq.ID:11 nt.592-916 reverse orientation *
Database EMBL, entry EMEST8:HSA11678, Accession number AA011678 3 August 1996 99% identity with Seq.ID:11 nt.341-758 reverse orientation *
Database EMBL, entry EMEST8:HSA11715, Accession number AA011715 3 August 1996 99% identity with Seq.ID:11 nt.120-601 *

Also Published As

Publication number Publication date Type
CA2286303A1 (en) 1998-10-15 application
EP0974058A2 (en) 2000-01-26 application
WO1998045712A2 (en) 1998-10-15 application
JP2001521383A (en) 2001-11-06 application

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