ATE312348T1 - Geneexpression der neurofilamentproteine und nachweis der alzheimeschen erkrankung - Google Patents
Geneexpression der neurofilamentproteine und nachweis der alzheimeschen erkrankungInfo
- Publication number
- ATE312348T1 ATE312348T1 AT94915396T AT94915396T ATE312348T1 AT E312348 T1 ATE312348 T1 AT E312348T1 AT 94915396 T AT94915396 T AT 94915396T AT 94915396 T AT94915396 T AT 94915396T AT E312348 T1 ATE312348 T1 AT E312348T1
- Authority
- AT
- Austria
- Prior art keywords
- disease
- proteins
- directed
- alzheime
- detection
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
- C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
- C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
- C07K14/4701—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
- C07K14/4711—Alzheimer's disease; Amyloid plaque core protein
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
- C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
- C07K14/4701—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
- C07K14/474—Pancreatic thread protein; Reg protein
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
- G01N33/6893—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids related to diseases not provided for elsewhere
- G01N33/6896—Neurological disorders, e.g. Alzheimer's disease
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2600/00—Oligonucleotides characterized by their use
- C12Q2600/158—Expression markers
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2800/00—Detection or diagnosis of diseases
- G01N2800/28—Neurological disorders
- G01N2800/2814—Dementia; Cognitive disorders
- G01N2800/2821—Alzheimer
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Organic Chemistry (AREA)
- Biomedical Technology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Molecular Biology (AREA)
- General Health & Medical Sciences (AREA)
- Neurology (AREA)
- Zoology (AREA)
- Genetics & Genomics (AREA)
- Medicinal Chemistry (AREA)
- Biochemistry (AREA)
- Analytical Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Immunology (AREA)
- Biophysics (AREA)
- Neurosurgery (AREA)
- Pathology (AREA)
- Toxicology (AREA)
- Microbiology (AREA)
- Wood Science & Technology (AREA)
- Gastroenterology & Hepatology (AREA)
- Physics & Mathematics (AREA)
- Hematology (AREA)
- Biotechnology (AREA)
- Urology & Nephrology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Hospice & Palliative Care (AREA)
- General Chemical & Material Sciences (AREA)
- General Engineering & Computer Science (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Cell Biology (AREA)
- Psychiatry (AREA)
- Animal Behavior & Ethology (AREA)
- Food Science & Technology (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US5055993A | 1993-04-20 | 1993-04-20 | |
| PCT/US1994/004321 WO1994023756A1 (en) | 1993-04-20 | 1994-04-20 | Neural thread protein gene expression and detection of alzheimer's disease |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE312348T1 true ATE312348T1 (de) | 2005-12-15 |
Family
ID=21965952
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT94915396T ATE312348T1 (de) | 1993-04-20 | 1994-04-20 | Geneexpression der neurofilamentproteine und nachweis der alzheimeschen erkrankung |
| AT04076254T ATE406444T1 (de) | 1993-04-20 | 1994-04-20 | Geneexpression der neurofilamentproteine und nachweis der alzheimeschen erkrankung |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT04076254T ATE406444T1 (de) | 1993-04-20 | 1994-04-20 | Geneexpression der neurofilamentproteine und nachweis der alzheimeschen erkrankung |
Country Status (11)
| Country | Link |
|---|---|
| EP (2) | EP0697893B1 (de) |
| JP (2) | JP3513859B2 (de) |
| KR (1) | KR100392244B1 (de) |
| AT (2) | ATE312348T1 (de) |
| CA (1) | CA2161097A1 (de) |
| DE (2) | DE69435136D1 (de) |
| DK (2) | DK0697893T3 (de) |
| ES (2) | ES2312913T3 (de) |
| NZ (1) | NZ266072A (de) |
| PT (1) | PT1564293E (de) |
| WO (1) | WO1994023756A1 (de) |
Families Citing this family (19)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5804560A (en) * | 1995-01-06 | 1998-09-08 | Sibia Neurosciences, Inc. | Peptide and peptide analog protease inhibitors |
| US5936078A (en) * | 1995-12-12 | 1999-08-10 | Kyowa Hakko Kogyo Co., Ltd. | DNA and protein for the diagnosis and treatment of Alzheimer's disease |
| KR19980702156A (ko) * | 1995-12-12 | 1998-07-15 | 히라따 다다시 | 신규 dna, 신규 폴리펩티드 및 신규 항체 |
| US7226730B1 (en) | 1997-02-26 | 2007-06-05 | The General Hospital Corporation | Transgenic animals and cell lines for screening drugs effective for the treatment or prevention of Alzheimer's Disease |
| AU749348B2 (en) | 1997-02-26 | 2002-06-27 | General Hospital Corporation, The | Transgenic animals and cell lines for screening drugs effective for the treatment or prevention of Alzheimer's disease |
| WO1998039967A1 (en) | 1997-03-12 | 1998-09-17 | The General Hospital Corporation | A method for treating or preventing alzheimer's disease |
| BR0209630A (pt) | 2001-05-16 | 2004-03-30 | Nymox Corp | Método de impedir morte de célula usando segmentos de proteìnas em cadeia neurais |
| EP1541166B1 (de) * | 2001-05-16 | 2007-12-19 | Nymox Corporation | Prävention des Zelltodes durch Verwendung von Segmenten der Neurofilamentproteinen |
| US6770797B2 (en) | 2001-06-01 | 2004-08-03 | Rhode Island Hospital | Non-Transgenic nonhuman model for Alzheimer's Disease using a AD7c-NTP nucleic acid |
| EP1714979A3 (de) * | 2001-11-16 | 2007-04-25 | Nymox Corporation | Peptide für die Behandlung von Tumoren und anderen Zuständen, die das entfernen oder zerstören von Zellen erfordern |
| US7317077B2 (en) | 2001-11-16 | 2008-01-08 | Nymox Pharmaceutical Corporation | Peptides effective in the treatment of tumors and other conditions requiring the removal or destruction of cells |
| US8067378B2 (en) | 2006-02-28 | 2011-11-29 | Nymox Pharmaceutical Corporation | Peptides effective in the treatment of tumors and other conditions requiring the removal or destruction of cells |
| US20080027005A1 (en) * | 2006-07-31 | 2008-01-31 | Paul Averback | Peptides effective in the treatment of tumors and other conditions requiring the removal or destruction of cells |
| US11628202B2 (en) | 2015-07-24 | 2023-04-18 | Nymox Corporation | Methods of reducing the need for surgery in patients suffering from benign prostatic hyperplasia |
| US10183058B2 (en) | 2016-06-17 | 2019-01-22 | Nymox Corporation | Method of preventing or reducing the progression of prostate cancer |
| US10172910B2 (en) | 2016-07-28 | 2019-01-08 | Nymox Corporation | Method of preventing or reducing the incidence of acute urinary retention |
| US10532081B2 (en) | 2016-09-07 | 2020-01-14 | Nymox Corporation | Method of ameliorating or preventing the worsening or the progression of symptoms of BPH |
| US10335453B2 (en) | 2017-03-01 | 2019-07-02 | Nymox Corporation | Compositions and methods for improving sexual function |
| WO2023217890A1 (en) * | 2022-05-10 | 2023-11-16 | F. Hoffmann-La Roche Ag | Antisense oligonucleotides targeting cfp-elk1 intergene region |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA2006332C (en) * | 1988-12-21 | 2003-04-08 | Suzanne De La Monte | Method of detecting neurological disease or dysfunction |
-
1994
- 1994-04-20 ES ES04076254T patent/ES2312913T3/es not_active Expired - Lifetime
- 1994-04-20 AT AT94915396T patent/ATE312348T1/de not_active IP Right Cessation
- 1994-04-20 WO PCT/US1994/004321 patent/WO1994023756A1/en active IP Right Grant
- 1994-04-20 CA CA002161097A patent/CA2161097A1/en not_active Abandoned
- 1994-04-20 AT AT04076254T patent/ATE406444T1/de not_active IP Right Cessation
- 1994-04-20 DK DK94915396T patent/DK0697893T3/da active
- 1994-04-20 PT PT04076254T patent/PT1564293E/pt unknown
- 1994-04-20 DK DK04076254T patent/DK1564293T3/da active
- 1994-04-20 NZ NZ266072A patent/NZ266072A/en not_active IP Right Cessation
- 1994-04-20 ES ES94915396T patent/ES2255054T3/es not_active Expired - Lifetime
- 1994-04-20 EP EP94915396A patent/EP0697893B1/de not_active Expired - Lifetime
- 1994-04-20 JP JP52355694A patent/JP3513859B2/ja not_active Expired - Fee Related
- 1994-04-20 DE DE69435136T patent/DE69435136D1/de not_active Expired - Fee Related
- 1994-04-20 KR KR1019950704656A patent/KR100392244B1/ko not_active IP Right Cessation
- 1994-04-20 DE DE69434844T patent/DE69434844T2/de not_active Expired - Fee Related
- 1994-04-20 EP EP04076254A patent/EP1564293B9/de not_active Expired - Lifetime
-
2003
- 2003-10-01 JP JP2003343063A patent/JP2004097227A/ja active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| EP1564293B9 (de) | 2009-08-19 |
| CA2161097A1 (en) | 1994-10-27 |
| DK1564293T3 (da) | 2009-01-12 |
| ES2255054T3 (es) | 2006-06-16 |
| DK0697893T3 (da) | 2006-02-20 |
| EP1564293B1 (de) | 2008-08-27 |
| EP1564293A1 (de) | 2005-08-17 |
| EP0697893A1 (de) | 1996-02-28 |
| JPH08509808A (ja) | 1996-10-15 |
| WO1994023756A1 (en) | 1994-10-27 |
| AU6666994A (en) | 1994-11-08 |
| AU674581B2 (en) | 1997-01-02 |
| DE69435136D1 (de) | 2008-10-09 |
| PT1564293E (pt) | 2008-12-02 |
| DE69434844T2 (de) | 2006-12-14 |
| JP3513859B2 (ja) | 2004-03-31 |
| JP2004097227A (ja) | 2004-04-02 |
| KR100392244B1 (ko) | 2003-11-28 |
| NZ266072A (en) | 1997-07-27 |
| DE69434844D1 (de) | 2006-10-19 |
| ATE406444T1 (de) | 2008-09-15 |
| EP0697893A4 (de) | 1996-12-18 |
| ES2312913T3 (es) | 2009-03-01 |
| EP0697893B1 (de) | 2005-12-07 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| UEP | Publication of translation of european patent specification |
Ref document number: 0697893 Country of ref document: EP |
|
| REN | Ceased due to non-payment of the annual fee |