DE3786200D1 - Diagnostische verfahren zum nachweis von lymphomen bei menschen. - Google Patents
Diagnostische verfahren zum nachweis von lymphomen bei menschen.Info
- Publication number
- DE3786200D1 DE3786200D1 DE8787305863T DE3786200T DE3786200D1 DE 3786200 D1 DE3786200 D1 DE 3786200D1 DE 8787305863 T DE8787305863 T DE 8787305863T DE 3786200 T DE3786200 T DE 3786200T DE 3786200 D1 DE3786200 D1 DE 3786200D1
- Authority
- DE
- Germany
- Prior art keywords
- translocation
- detecting
- lymphomas
- humans
- diagnostic procedure
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/82—Translation products from oncogenes
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
- C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
- C12Q1/6886—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material for cancer
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/574—Immunoassay; Biospecific binding assay; Materials therefor for cancer
- G01N33/5748—Immunoassay; Biospecific binding assay; Materials therefor for cancer involving oncogenic proteins
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2600/00—Oligonucleotides characterized by their use
- C12Q2600/156—Polymorphic or mutational markers
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2600/00—Oligonucleotides characterized by their use
- C12Q2600/158—Expression markers
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S436/00—Chemistry: analytical and immunological testing
- Y10S436/811—Test for named disease, body condition or organ function
- Y10S436/813—Cancer
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S530/00—Chemistry: natural resins or derivatives; peptides or proteins; lignins or reaction products thereof
- Y10S530/806—Antigenic peptides or proteins
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S530/00—Chemistry: natural resins or derivatives; peptides or proteins; lignins or reaction products thereof
- Y10S530/827—Proteins from mammals or birds
- Y10S530/828—Cancer
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Immunology (AREA)
- Engineering & Computer Science (AREA)
- Organic Chemistry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Molecular Biology (AREA)
- Oncology (AREA)
- Analytical Chemistry (AREA)
- Genetics & Genomics (AREA)
- Pathology (AREA)
- General Health & Medical Sciences (AREA)
- Biochemistry (AREA)
- Hematology (AREA)
- Biomedical Technology (AREA)
- Physics & Mathematics (AREA)
- Zoology (AREA)
- Urology & Nephrology (AREA)
- Microbiology (AREA)
- Medicinal Chemistry (AREA)
- Wood Science & Technology (AREA)
- Hospice & Palliative Care (AREA)
- Biophysics (AREA)
- Biotechnology (AREA)
- General Physics & Mathematics (AREA)
- Gastroenterology & Hepatology (AREA)
- Cell Biology (AREA)
- Food Science & Technology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Engineering & Computer Science (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Saccharide Compounds (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Peptides Or Proteins (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US06/883,687 US5015568A (en) | 1986-07-09 | 1986-07-09 | Diagnostic methods for detecting lymphomas in humans |
Publications (2)
Publication Number | Publication Date |
---|---|
DE3786200D1 true DE3786200D1 (de) | 1993-07-22 |
DE3786200T2 DE3786200T2 (de) | 1993-10-07 |
Family
ID=25383120
Family Applications (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE198787305863T Pending DE252685T1 (de) | 1986-07-09 | 1987-07-02 | Diagnostische verfahren zum nachweis von lymphomen bei menschen. |
DE87305863T Expired - Lifetime DE3786200T2 (de) | 1986-07-09 | 1987-07-02 | Diagnostische Verfahren zum Nachweis von Lymphomen bei Menschen. |
Family Applications Before (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE198787305863T Pending DE252685T1 (de) | 1986-07-09 | 1987-07-02 | Diagnostische verfahren zum nachweis von lymphomen bei menschen. |
Country Status (9)
Country | Link |
---|---|
US (5) | US5015568A (de) |
EP (1) | EP0252685B1 (de) |
JP (1) | JPS63100379A (de) |
AT (1) | ATE90792T1 (de) |
AU (1) | AU602704B2 (de) |
CA (1) | CA1340827C (de) |
DE (2) | DE252685T1 (de) |
ES (1) | ES2003064T3 (de) |
GR (1) | GR880300131T1 (de) |
Families Citing this family (90)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5015568A (en) * | 1986-07-09 | 1991-05-14 | The Wistar Institute | Diagnostic methods for detecting lymphomas in humans |
US6841541B1 (en) | 1992-02-21 | 2005-01-11 | The Trustees Of The University Of Pennsylvania | Regulation of BCL-2-gene expression |
US5831066A (en) | 1988-12-22 | 1998-11-03 | The Trustees Of The University Of Pennsylvania | Regulation of bcl-2 gene expression |
AU5932790A (en) * | 1989-07-03 | 1991-01-17 | Temple University | Tcl-5 gene rearrangement involved in t-cell leukemia and melanoma |
JPH05504476A (ja) * | 1989-12-27 | 1993-07-15 | アメリカ合衆国 | ヒト胃癌検出用診断プローブ |
WO1991013172A1 (en) * | 1990-02-23 | 1991-09-05 | The Board Of Trustees Of The Leland Stanford Junior University | Transcription factors having a pathogenetic role in human neoplasias |
IT1255770B (it) * | 1992-05-22 | 1995-11-15 | Consiglio Nazionale Ricerche | Oligonucleotidi antisenso ad attivita' antitumorale, composizioni farmaceutiche che li comprendono, e loro impieghi |
US6902732B2 (en) | 1992-06-12 | 2005-06-07 | Massachusetts Institute Of Technology | Identification and characterization of a gene which protects cells from programmed cell death and uses therefor |
WO1993025683A1 (en) | 1992-06-12 | 1993-12-23 | Massachusetts Institute Of Technology | A gene which prevents programmed cell death |
US5501952A (en) * | 1992-07-17 | 1996-03-26 | Aprogenex, Inc. | Analogues of reporter groups as background reducers in hybridization assays |
US5641672A (en) * | 1993-06-09 | 1997-06-24 | The Trustees Of Columbia University In The City Of New York | Cloning and uses of the genetic locus bcl-6 |
US5646008A (en) | 1993-06-22 | 1997-07-08 | The Regent Of The University Of Michigan | Vertebrate apoptosis gene: compositions and methods |
US5622852A (en) * | 1994-10-31 | 1997-04-22 | Washington University | Bcl-x/Bcl-2 associated cell death regulator |
US5529925A (en) | 1993-12-03 | 1996-06-25 | St. Jude Children's Research Hospital | Nucleic acid sequences and fusion proteins present in human t(2;5) lymphoma |
US6696548B2 (en) | 1993-12-03 | 2004-02-24 | St. Jude Children's Research Hospital | Antibodies for recognition of alk protein tyrosine/kinase receptor |
US5672686A (en) * | 1994-08-09 | 1997-09-30 | Immunogen, Inc. | Bcl-Y - specific antibodies |
US7175995B1 (en) | 1994-10-27 | 2007-02-13 | Thomas Jefferson University | TCL-1 protein and related methods |
US5985598A (en) * | 1994-10-27 | 1999-11-16 | Thomas Jefferson University | TCL-1 gene and protein and related methods and compositions |
US5789389A (en) * | 1995-03-17 | 1998-08-04 | Board Of Trustees Of University Of Illinois | BCL2 derived genetic elements associated with sensitivity to chemotherapeutic drugs |
US5695944A (en) * | 1995-05-05 | 1997-12-09 | Thomas Jefferson University | Modulation of bcl-2 phosphorylation |
US6221615B1 (en) * | 1995-05-12 | 2001-04-24 | Apoptosis Technology, Inc. | Peptides and compositions which modulate apoptosis |
US5656725A (en) * | 1995-05-12 | 1997-08-12 | Apoptosis Technology, Inc. | Peptides and compositions which modulate apoptosis |
US5789201A (en) * | 1996-02-23 | 1998-08-04 | Cocensys, Inc. | Genes coding for bcl-y a bcl-2 homologue |
AUPN896596A0 (en) * | 1996-03-27 | 1996-04-26 | Walter And Eliza Hall Institute Of Medical Research, The | Therapeutic molecules |
AU728863B2 (en) * | 1996-03-27 | 2001-01-18 | Walter And Eliza Hall Institute Of Medical Research, The | A novel mammalian gene, bcl-w, belongs to the bcl-2 family of apoptosis-controlling genes |
US5821082A (en) | 1996-05-23 | 1998-10-13 | St. Louis University Health Sciences Center | Anti-proliferation domain of a human Bcl-2 and DNA encoding the same |
US6977244B2 (en) * | 1996-10-04 | 2005-12-20 | Board Of Regents, The University Of Texas Systems | Inhibition of Bcl-2 protein expression by liposomal antisense oligodeoxynucleotides |
US5837838A (en) | 1997-03-14 | 1998-11-17 | The Burnham Institute | Bax inhibitor proteins |
US6337184B1 (en) | 1997-04-01 | 2002-01-08 | Jeffrey B. Miller | Molecular marker for muscle stem cells |
EP0878552A1 (de) * | 1997-05-13 | 1998-11-18 | Erasmus Universiteit Rotterdam | Molekularer Nachweis von chromosomalen Veränderungen |
US6849400B1 (en) | 1997-07-23 | 2005-02-01 | Gen-Probe Incorporated | Methods for detecting and measuring spliced nucleic acids |
US7285288B1 (en) | 1997-10-03 | 2007-10-23 | Board Of Regents, The University Of Texas System | Inhibition of Bcl-2 protein expression by liposomal antisense oligodeoxynucleotides |
US7704962B1 (en) | 1997-10-03 | 2010-04-27 | Board Of Regents, The University Of Texas System | Small oligonucleotides with anti-tumor activity |
US20010041342A1 (en) * | 1998-04-01 | 2001-11-15 | The General Hospital Corporation, A Massachusetts Corporation | Molecular marker for muscle stem cells |
WO1999057309A1 (en) * | 1998-05-04 | 1999-11-11 | Dako A/S | Method and probes for the detection of chromosome aberrations |
EP1247093B1 (de) * | 2000-01-14 | 2005-03-23 | MIGENIX Corp. | Screening-assays unter verwendung von intramitochondrialem kalzium |
WO2001052639A1 (en) * | 2000-01-21 | 2001-07-26 | Beth Israel Deaconess Medical Center | Use of pro-apoptotic factors in treatment of atherosclerosis |
US7795232B1 (en) | 2000-08-25 | 2010-09-14 | Genta Incorporated | Methods of treatment of a bcl-2 disorder using bcl-2 antisense oligomers |
US20030077590A1 (en) * | 2000-09-22 | 2003-04-24 | Pedersen Finn Skou | Methods for diagnosis and treatment of diseases associated with altered expression of neurogranin |
US20030044803A1 (en) * | 2000-09-22 | 2003-03-06 | Pedersen Finn Skou | Methods for diagnosis and treatment of diseases associated with altered expression of JAK1 |
US20040147473A1 (en) * | 2000-11-10 | 2004-07-29 | Warrell Raymond P. | Methods of treatment of a bcl-2 disorder using bcl-2 antisense oligomers |
US20070098728A1 (en) * | 2001-09-24 | 2007-05-03 | Pedersen Finn S | Novel compositions and methods in cancer |
JP2005519624A (ja) * | 2002-03-13 | 2005-07-07 | ジェノミック ヘルス, インコーポレイテッド | 生検腫瘍組織での遺伝子発現プロファイリング |
JP4606879B2 (ja) | 2002-11-15 | 2011-01-05 | ジェノミック ヘルス, インコーポレイテッド | Egfr陽性癌の遺伝子発現プロファイリング |
US20040231909A1 (en) | 2003-01-15 | 2004-11-25 | Tai-Yang Luh | Motorized vehicle having forward and backward differential structure |
AU2004211955B2 (en) * | 2003-02-06 | 2009-05-14 | Cedars-Sinai Medical Center | Gene expression markers for response to EGFR inhibitor drugs |
EP1597391B1 (de) * | 2003-02-20 | 2008-10-29 | Genomic Health, Inc. | Benutzung von intronischen rna sequenzen zur quantifizierung der genexpression |
JP2007507222A (ja) * | 2003-05-28 | 2007-03-29 | ゲノミック ヘルス, インコーポレイテッド | 化学療法に対する応答を予測するための遺伝子発現マーカー |
AU2004248140A1 (en) * | 2003-05-30 | 2004-12-23 | Cedars-Sinai Medical Center | Gene expression markers for response to EGFR inhibitor drugs |
PL3470535T3 (pl) * | 2003-06-24 | 2020-08-24 | Genomic Health, Inc. | Prognozowanie prawdopodobieństwa ponownego wystąpienia raka |
US7526387B2 (en) * | 2003-07-10 | 2009-04-28 | Genomic Health, Inc. | Expression profile algorithm and test for cancer prognosis |
DE602004031368D1 (de) * | 2003-12-23 | 2011-03-24 | Genomic Health Inc | Universelle vervielfältigung von fragmentierter rns |
US7871769B2 (en) | 2004-04-09 | 2011-01-18 | Genomic Health, Inc. | Gene expression markers for predicting response to chemotherapy |
CA2573590A1 (en) * | 2004-07-12 | 2006-02-16 | Sbarro Health Research Organization | Methods for determining presence of cancer by analyzing the expression of cdk9 and/or cyclin t1 in lymphoid tissue |
CA2583004A1 (en) * | 2004-10-04 | 2006-04-20 | University Of Washington | Methods of inhibiting cell death or inflammation in a mammal |
CA3061785A1 (en) * | 2004-11-05 | 2006-05-18 | Genomic Health, Inc. | Predicting response to chemotherapy using gene expression markers |
CA2585561C (en) | 2004-11-05 | 2018-07-17 | Genomic Health, Inc. | Esr1, pgr, bcl2 and scube2 group score as indicators of breast cancer prognosis and prediction of treatment response |
CN103866018B (zh) * | 2005-08-01 | 2016-05-25 | 俄亥俄州立大学研究基金会 | 用于乳腺癌的诊断、预后和治疗的基于MicroRNA的方法和组合物 |
CN101296702B (zh) * | 2005-09-12 | 2012-11-28 | 俄亥俄州立大学研究基金会 | 用于诊断或治疗bcl2相关癌症的组合物和方法 |
WO2007044413A2 (en) * | 2005-10-05 | 2007-04-19 | The Ohio State University Research Foundation | Wwox gene, vectors containing the same, and uses in treatment of cancer |
AU2007205257B2 (en) | 2006-01-05 | 2013-07-25 | The Ohio State University Research Foundation | MicroRNA expression abnormalities in pancreatic endocrine and acinar tumors |
EP2502630B1 (de) | 2006-01-05 | 2015-03-11 | The Ohio State University Research Foundation | Verfahren und Zusammensetzungen auf Mikro-RNA-Basis zur Diagnose, Prognose und Behandlung von Lungenkrebs |
ES2527592T3 (es) | 2006-01-05 | 2015-01-27 | The Ohio State University Research Foundation | Métodos basados en microARN para el diagnóstico del cáncer de colon |
EP1996940B1 (de) * | 2006-02-09 | 2011-12-21 | University of South Florida | Nachweis von krebs anhand von erhöhten bcl-2-konzentrationen |
AU2007227423B2 (en) | 2006-03-20 | 2013-11-07 | The Ohio State University Research Foundation | MicroRNA fingerprints during human megakaryocytopoiesis |
AU2007272947B2 (en) * | 2006-07-13 | 2013-06-06 | The Government Of The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services | Micro-RNA-based methods and compositions for the diagnosis and treatment of colon cancer-related diseases |
AU2007346101B2 (en) * | 2006-09-19 | 2013-08-15 | The Ohio State University Research Foundation | TCL1 expression in chronic lymphocytic leukemia (CLL) regulated by miR-29 and miR-181 |
CA2667617A1 (en) | 2006-11-01 | 2008-05-08 | The Ohio State University Research Foundation | Microrna expression signature for predicting survival and metastases in hepatocellular carcinoma |
WO2008094545A2 (en) * | 2007-01-31 | 2008-08-07 | The Ohio State University Research Foundation | Mic orna-based methods and compositions for the treatment of acute myeloid leukemia |
AU2008248319B2 (en) * | 2007-04-30 | 2013-09-05 | The Ohio State University Research Foundation | Methods for differentiating pancreatic cancer from normal pancreatic function and/or chronic pancreatitis |
US8465917B2 (en) * | 2007-06-08 | 2013-06-18 | The Ohio State University Research Foundation | Methods for determining heptocellular carcinoma subtype and detecting hepatic cancer stem cells |
CN101918424A (zh) | 2007-06-15 | 2010-12-15 | 俄亥俄州立大学研究基金会 | 用于靶向由Drosha介导的微小RNA加工的致癌ALL-1融合蛋白 |
CN101809169B (zh) * | 2007-07-31 | 2013-07-17 | 俄亥俄州立大学研究基金会 | 通过靶向dnmt3a和dnmt3b恢复甲基化的方法 |
US8465918B2 (en) | 2007-08-03 | 2013-06-18 | The Ohio State University Research Foundation | Ultraconserved regions encoding ncRNAs |
CA2926831A1 (en) * | 2007-08-22 | 2009-02-26 | The Ohio State University Research Foundation | Methods and compositions for inducing deregulation of epha7 and erk phosphorylation in human acute leukemias |
CA2698771A1 (en) * | 2007-09-06 | 2009-03-12 | The Ohio State University Research Foundation | Microrna signatures in human ovarian cancer |
WO2009049129A1 (en) * | 2007-10-11 | 2009-04-16 | The Ohio State University Research Foundation | Methods and compositions for the diagnosis and treatment of esphageal adenocarcinomas |
EP2201112A4 (de) | 2007-10-26 | 2011-02-02 | Univ Ohio State Res Found | Verfahren zur identifizierung einer fhit-interaktion und verwendung |
CN101918594A (zh) * | 2007-11-30 | 2010-12-15 | 俄亥俄州立大学研究基金会 | 肺癌中外周血中的微rna表达特征谱和靶向 |
AU2009219193A1 (en) * | 2008-02-28 | 2009-09-03 | The Ohio State University Research Foundation | MicroRNA signatures associated with human chronic lymphocytic leukemia (CCL) and uses thereof |
EP2799557B1 (de) * | 2008-02-28 | 2016-09-07 | The Ohio State University Research Foundation | MiR-32 Antagonisten zur Erhöhung der Empfindlichkeit von Prostatakrebszellen für Apoptose |
ES2433940T3 (es) | 2008-06-11 | 2013-12-13 | The Government Of The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services | Uso de la familia miR-26 como marcador predictivo del carcinoma hepatocelular y sensibilidad a la terapia |
US9569912B2 (en) | 2008-06-26 | 2017-02-14 | Shopatm Bv (Sarl) | Article storage and retrieval apparatus and vending machine |
CN102803511A (zh) | 2009-11-23 | 2012-11-28 | 俄亥俄州立大学 | 用于影响肿瘤细胞生长、迁移和侵袭的材料和方法 |
WO2012065049A1 (en) | 2010-11-12 | 2012-05-18 | The Ohio State University Research Foundation | Materials and methods related to microrna-21, mismatch repair, and colorectal cancer |
CA2817982C (en) | 2010-11-15 | 2020-06-30 | The Regents Of The University Of Michigan | Controlled release mucoadhesive systems |
US8664192B2 (en) | 2011-03-07 | 2014-03-04 | The Ohio State University | Mutator activity induced by microRNA-155 (miR-155) links inflammation and cancer |
JP2014530612A (ja) | 2011-10-14 | 2014-11-20 | ジ・オハイオ・ステート・ユニバーシティ | 卵巣がんに関する方法および材料 |
CN104619353A (zh) | 2011-12-13 | 2015-05-13 | 俄亥俄州国家创新基金会 | 与miR-21和miR-29a相关的方法和组合物、外切体抑制和癌症转移 |
WO2013110053A1 (en) | 2012-01-20 | 2013-07-25 | The Ohio State University | Breast cancer biomarker signatures for invasiveness and prognosis |
Family Cites Families (12)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3755086A (en) * | 1971-02-09 | 1973-08-28 | Hoffmann La Roche | Diagnostic method utilizing synthetic deoxyrilionucleotide oligomer template |
US4535058A (en) * | 1982-10-01 | 1985-08-13 | Massachusetts Institute Of Technology | Characterization of oncogenes and assays based thereon |
US4661586A (en) * | 1981-11-17 | 1987-04-28 | The Board Of Trustees Of The Leland Stanford Junior University | Monoclonal anti-idiotype antibodies |
US4582788A (en) * | 1982-01-22 | 1986-04-15 | Cetus Corporation | HLA typing method and cDNA probes used therein |
US4513088A (en) * | 1983-03-30 | 1985-04-23 | The Board Of Trustees Of The Leland Stanford Junior University | Assay for monoclonal antibody against surface Ig of a human B cell tumor |
US4798787A (en) * | 1984-09-19 | 1989-01-17 | Cetus Corporation | Peptide antibodies and their use in detecting oncogene products |
US4679918A (en) * | 1984-10-23 | 1987-07-14 | Ace Ronald S | Ophthalmic glass/plastic laminated lens having photochromic characteristics and assembly thereof |
US4701409A (en) * | 1984-11-15 | 1987-10-20 | The Wistar Institute | Detection of B-cell neoplasms |
US4692405A (en) * | 1985-03-05 | 1987-09-08 | Dana-Farber Cancer Institute, Inc. | Monoclonal antibodies to antigen on activated human B-cells and assay therefor, protein antigenic determinant therefor and method of making same |
IL79755A0 (en) * | 1985-08-21 | 1986-11-30 | Oncogene Science Inc | Immunoassay for detection of ras encoded protein |
US5015568A (en) * | 1986-07-09 | 1991-05-14 | The Wistar Institute | Diagnostic methods for detecting lymphomas in humans |
IT1244983B (it) * | 1991-04-29 | 1994-09-13 | Raggio Italgene Spa | Procedimento per rivelare sequenze di acidi nucleici e kit per la sua utilizzazione. |
-
1986
- 1986-07-09 US US06/883,687 patent/US5015568A/en not_active Expired - Lifetime
-
1987
- 1987-07-02 AT AT87305863T patent/ATE90792T1/de not_active IP Right Cessation
- 1987-07-02 EP EP87305863A patent/EP0252685B1/de not_active Expired - Lifetime
- 1987-07-02 DE DE198787305863T patent/DE252685T1/de active Pending
- 1987-07-02 DE DE87305863T patent/DE3786200T2/de not_active Expired - Lifetime
- 1987-07-02 ES ES87305863T patent/ES2003064T3/es not_active Expired - Lifetime
- 1987-07-08 AU AU75328/87A patent/AU602704B2/en not_active Expired
- 1987-07-08 CA CA000541606A patent/CA1340827C/en not_active Expired - Lifetime
- 1987-07-09 JP JP62172023A patent/JPS63100379A/ja active Pending
-
1988
- 1988-12-16 GR GR88300131T patent/GR880300131T1/el unknown
-
1992
- 1992-12-23 US US07/994,941 patent/US5595869A/en not_active Expired - Lifetime
-
1994
- 1994-04-18 US US08/228,704 patent/US5459251A/en not_active Expired - Lifetime
-
1995
- 1995-05-05 US US08/435,181 patent/US5523393A/en not_active Expired - Lifetime
- 1995-05-05 US US08/435,193 patent/US5506344A/en not_active Expired - Lifetime
Also Published As
Publication number | Publication date |
---|---|
US5595869A (en) | 1997-01-21 |
EP0252685A2 (de) | 1988-01-13 |
ES2003064T3 (es) | 1994-09-01 |
JPS63100379A (ja) | 1988-05-02 |
EP0252685A3 (en) | 1990-07-11 |
ATE90792T1 (de) | 1993-07-15 |
AU7532887A (en) | 1988-02-18 |
DE3786200T2 (de) | 1993-10-07 |
EP0252685B1 (de) | 1993-06-16 |
AU602704B2 (en) | 1990-10-25 |
US5015568A (en) | 1991-05-14 |
US5506344A (en) | 1996-04-09 |
ES2003064A4 (es) | 1988-10-16 |
US5459251A (en) | 1995-10-17 |
DE252685T1 (de) | 1988-06-30 |
US5523393A (en) | 1996-06-04 |
CA1340827C (en) | 1999-11-23 |
GR880300131T1 (en) | 1988-12-16 |
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