DK1558612T3 - Imidazopyridinderivater, fremgangsmåde til fremstilling heraf og farmaceutiske sammensætninger indeholdende disse - Google Patents

Imidazopyridinderivater, fremgangsmåde til fremstilling heraf og farmaceutiske sammensætninger indeholdende disse

Info

Publication number
DK1558612T3
DK1558612T3 DK03767889T DK03767889T DK1558612T3 DK 1558612 T3 DK1558612 T3 DK 1558612T3 DK 03767889 T DK03767889 T DK 03767889T DK 03767889 T DK03767889 T DK 03767889T DK 1558612 T3 DK1558612 T3 DK 1558612T3
Authority
DK
Denmark
Prior art keywords
processes
preparation
pharmaceutical compositions
compositions containing
imidazopyridine derivatives
Prior art date
Application number
DK03767889T
Other languages
Danish (da)
English (en)
Inventor
Sylvain Rault
Jean-Charles Lancelot
Marina Kopp
Daniel-Henri Caignard
Pierre Renard
Jean-Guy Bizot-Espiard
Bruno Pfeiffer
Original Assignee
Servier Lab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Servier Lab filed Critical Servier Lab
Application granted granted Critical
Publication of DK1558612T3 publication Critical patent/DK1558612T3/da

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D471/00Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04Ortho-condensed systems
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/04Anorexiants; Antiobesity agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/06Antihyperlipidemics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/08Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/10Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Diabetes (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Urology & Nephrology (AREA)
  • Vascular Medicine (AREA)
  • Child & Adolescent Psychology (AREA)
  • Emergency Medicine (AREA)
  • Endocrinology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
DK03767889T 2002-11-05 2003-11-04 Imidazopyridinderivater, fremgangsmåde til fremstilling heraf og farmaceutiske sammensætninger indeholdende disse DK1558612T3 (da)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR0213802A FR2846656B1 (fr) 2002-11-05 2002-11-05 Nouveaux derives d'imidazopyridine, leur procede de preparation et les compositions pharmaceutiques qui les contiennent

Publications (1)

Publication Number Publication Date
DK1558612T3 true DK1558612T3 (da) 2006-12-27

Family

ID=32104440

Family Applications (1)

Application Number Title Priority Date Filing Date
DK03767889T DK1558612T3 (da) 2002-11-05 2003-11-04 Imidazopyridinderivater, fremgangsmåde til fremstilling heraf og farmaceutiske sammensætninger indeholdende disse

Country Status (27)

Country Link
US (1) US7098220B2 (zh)
EP (1) EP1558612B1 (zh)
JP (1) JP2006508111A (zh)
KR (1) KR100717488B1 (zh)
CN (1) CN100335480C (zh)
AR (1) AR041882A1 (zh)
AT (1) ATE337317T1 (zh)
AU (1) AU2003292323A1 (zh)
BR (1) BR0315800A (zh)
CA (1) CA2504008A1 (zh)
CY (1) CY1105752T1 (zh)
DE (1) DE60307875T2 (zh)
DK (1) DK1558612T3 (zh)
EA (1) EA008446B1 (zh)
ES (1) ES2271653T3 (zh)
FR (1) FR2846656B1 (zh)
HK (1) HK1081964A1 (zh)
MA (1) MA27411A1 (zh)
MX (1) MXPA05004791A (zh)
MY (1) MY135191A (zh)
NO (1) NO20052710L (zh)
NZ (1) NZ539599A (zh)
PL (1) PL375373A1 (zh)
PT (1) PT1558612E (zh)
UA (1) UA80579C2 (zh)
WO (1) WO2004043957A1 (zh)
ZA (1) ZA200503234B (zh)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1754483A1 (en) 2005-08-18 2007-02-21 Merck Sante Use of thienopyridone derivatives as AMPK activators and pharmaceutical compositions containing them
FR2903695B1 (fr) 2006-07-13 2008-10-24 Merck Sante Soc Par Actions Si Utilisation de derives d'imidazole activateurs de l'ampk, leur procede de preparation et les compositions pharmaceutiques qui les contiennent
WO2008016730A2 (en) * 2006-08-02 2008-02-07 Targeted Molecular Diagnostics, Llc Compositions and methods for reducing cellular fat
US8163505B2 (en) 2007-05-22 2012-04-24 The Penn State Research Foundation Methods using PBK1 for identifying agents that treat metabolic disorders
US8507473B2 (en) 2008-09-11 2013-08-13 Arena Pharmaceuticals, Inc. 3H-imidazo[4,5-b]pyridin-5-ol derivatives useful in the treatment of GPR81 receptor disorders
EP3924343A1 (en) * 2008-09-26 2021-12-22 Merck Sharp & Dohme Corp. Novel cyclic benzimidazole derivatives useful anti-diabetic agents
EP2348857B1 (en) 2008-10-22 2016-02-24 Merck Sharp & Dohme Corp. Novel cyclic benzimidazole derivatives useful anti-diabetic agents
CA2741672A1 (en) * 2008-10-31 2010-05-06 Merck Sharp & Dohme Corp. Novel cyclic benzimidazole derivatives useful anti-diabetic agents
WO2010103040A1 (en) 2009-03-10 2010-09-16 INSERM (Institut National de la Santé et de la Recherche Médicale) 5'-adenosine monophosphate-activated protein kinase (ampk) activators for treating pulmonary hypertension
JP2013510834A (ja) 2009-11-16 2013-03-28 メリテク [1,5]‐ジアゾシン誘導体
JP2013520502A (ja) 2010-02-25 2013-06-06 メルク・シャープ・エンド・ドーム・コーポレイション 有用な抗糖尿病薬である新規な環状ベンズイミダゾール誘導体
WO2012033149A1 (ja) * 2010-09-10 2012-03-15 塩野義製薬株式会社 Ampk活性化作用を有するヘテロ環縮合イミダゾール誘導体
US8889730B2 (en) 2012-04-10 2014-11-18 Pfizer Inc. Indole and indazole compounds that activate AMPK
EP2906040B1 (en) * 2012-08-22 2021-02-17 Merck Sharp & Dohme Corp. Novel benzimidazole tetrahydropyran derivatives
ES2885424T3 (es) * 2013-03-15 2021-12-13 Knopp Biosciences Llc Imidazo(4,5-B)piridin-2-il amidas como activadores del canal Kv7
US9394285B2 (en) 2013-03-15 2016-07-19 Pfizer Inc. Indole and indazole compounds that activate AMPK
US9481653B2 (en) 2014-09-12 2016-11-01 Knopp Biosciences Llc Benzoimidazol-1,2-yl amides as Kv7 channel activators
WO2023044364A1 (en) 2021-09-15 2023-03-23 Enko Chem, Inc. Protoporphyrinogen oxidase inhibitors

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2707984B1 (fr) * 1993-07-23 1995-09-01 Adir Nouvelles pipérazines substituées, leur procédé de préparation et les compositions les contenant.
MXPA03006730A (es) * 1996-12-11 2003-10-24 Aventis Pharma Inc Preparacion de 4-hidroxi-3-nitro-2(1h)-piridona.
WO2000012089A1 (en) * 1998-08-31 2000-03-09 Merck & Co., Inc. Novel angiogenesis inhibitors
US6271241B1 (en) * 1999-04-02 2001-08-07 Neurogen Corporation Cycloalkyl and aryl fused aminoalkyl-imidazole derivatives: modulators and GLP-1 receptors

Also Published As

Publication number Publication date
US7098220B2 (en) 2006-08-29
UA80579C2 (en) 2007-10-10
JP2006508111A (ja) 2006-03-09
EP1558612B1 (fr) 2006-08-23
DE60307875T2 (de) 2007-04-12
CN100335480C (zh) 2007-09-05
EA200500717A1 (ru) 2005-10-27
FR2846656A1 (fr) 2004-05-07
HK1081964A1 (en) 2006-05-26
KR100717488B1 (ko) 2007-05-14
CN1711261A (zh) 2005-12-21
WO2004043957A1 (fr) 2004-05-27
EA008446B1 (ru) 2007-06-29
ZA200503234B (en) 2006-06-28
DE60307875D1 (de) 2006-10-05
BR0315800A (pt) 2005-09-20
AU2003292323A1 (en) 2004-06-03
ES2271653T3 (es) 2007-04-16
NO20052710L (no) 2005-06-06
EP1558612A1 (fr) 2005-08-03
MXPA05004791A (es) 2005-07-22
CA2504008A1 (fr) 2004-05-27
PT1558612E (pt) 2006-12-29
MA27411A1 (fr) 2005-06-01
ATE337317T1 (de) 2006-09-15
CY1105752T1 (el) 2010-12-22
MY135191A (en) 2008-02-29
NZ539599A (en) 2007-06-29
PL375373A1 (en) 2005-11-28
AR041882A1 (es) 2005-06-01
FR2846656B1 (fr) 2004-12-24
US20060069117A1 (en) 2006-03-30
KR20050084663A (ko) 2005-08-26

Similar Documents

Publication Publication Date Title
DK1163227T3 (da) Bicykliske heterocykliske forbindelser, farmaceutiske præparater indeholdende disse forbindelser og fremgangsmåder til fremstilling deraf
DK1523488T3 (da) Nye thiophenglycosidderivater, fremgangsmåder til deres fremstilling, lægemidler indeholdende disse forbindelser og deres anvendelse
NO20035220D0 (no) Karboksamidsubstituerte fenylureaderivater og fremgangsmåter for fremstilling av disse som legemidler
DK1558612T3 (da) Imidazopyridinderivater, fremgangsmåde til fremstilling heraf og farmaceutiske sammensætninger indeholdende disse
DK1320531T3 (da) Bicyclo-pyrazoler, der er aktive som kinase inhibitorer, fremgangsmåde til fremstilling deraf og farmaceutiske sammensætninger, der indeholder disse
DK1202965T3 (da) Indolderivater, fremgangsmåde til fremstilling deraf, farmaceutiske præparater indeholdende disse og deres medicinske anvendelse
DK1720544T3 (da) Nye azabicykliske derivater, fremstillingsmetode hertil og farmaceutiske sammensætninger indeholdende disse
DK1490062T3 (da) Glukokortikoidmimetika, fremgangsmåder til fremstilling deraf, farmaceutiske sammensætninger og anvendelser deraf
DK1560826T3 (da) Pyridopyrimidinonderivater, fremgangsmåde til fremstiling heraf og farmaceutiske sammensætninger indeholdende disse
DK1845978T3 (da) Substituerede pyrazolopyridiner, sammensætninger, som indeholder disse, fremgangsmåde til fremstilling heraf, og anvendelse heraf
IL169818A0 (en) Adamantane derivatives, processes for their preparation and pharmaceutical composition containing them
DK1448195T3 (da) N-adamantylmethylderivater og mellemprodukter som farmaceutiske præparater og fremgangsmåde til fremstilling deraf
IL164798A0 (en) Benzothiadiazepine derivatives, processes for their preparation and pharmaceutical compositions containing them
IS7798A (is) Efnasambönd, lyfjablöndur og aðferðir
DK1670769T3 (da) Benzimidazol-derivater, sammensætninger indeholdende disse, fremstilling deraf og anvendelser deraf
DK1707564T3 (da) Indanyl-piperazinderivater, fremgangsmåde til fremstilling heraf og farmaceutiske sammensætninger indeholdende disse
DK1322158T3 (da) Farmaceutiske præparater med langvarig frigivelse, som indeholder metformin, og fremgangsmåde til fremstilling deraf
DK1495023T3 (da) Hidtil ukendte derivater af 1,2,3-substitueret indolizin, FGF-inhibitorer, fremgangsmåde for fremstilling og farmaceutiske sammensætninger indeholdende disse
NO20015659D0 (no) Purinderivater, fremstillingsmetode og farmasöytiske preparater inneholdende disse
DK2083007T3 (da) Tiotropiumsalte, fremgangsmåder til deres fremstilling og lægemiddelformuleringer indeholdende disse
DK1655030T3 (da) Benzothiadiazinforbindelser, fremgangsmåde til fremstilling heraf og farmaceutiske sammensætninger, som indeholder disse
DK1122254T3 (da) 4-sulfonamidpiperidinderivater, fremgangsmåde til fremstilling heraf og farmaceutiske sammensætninger indeholdende disse
DK2067779T3 (da) Tiotropiumsalte, fremgangsmåde til deres fremstilling og lægemiddelformuleringer indeholdende disse
NO20016404L (no) Naftyridinderivater, fremgangsmåter for deres fremstilling, deres anvendelse og farmasöytiske preparater omfattende disse
DK1275647T3 (da) Octahydro-1H-pyrido[1,2-a]pyrazinderivater, fremgangsmåde til fremstilling heraf og farmaceutiske sammensætninger indeholdende disse