DK1556378T3 - Acylderivater af 5-(2-(4-(1,2 benzisothiazol-3-yl)-1piperazinyl)ethyl)-6-chloro-1,3-dihydro-2H-indo-2-on med neuroleptisk aktivitet - Google Patents

Acylderivater af 5-(2-(4-(1,2 benzisothiazol-3-yl)-1piperazinyl)ethyl)-6-chloro-1,3-dihydro-2H-indo-2-on med neuroleptisk aktivitet

Info

Publication number
DK1556378T3
DK1556378T3 DK03751112T DK03751112T DK1556378T3 DK 1556378 T3 DK1556378 T3 DK 1556378T3 DK 03751112 T DK03751112 T DK 03751112T DK 03751112 T DK03751112 T DK 03751112T DK 1556378 T3 DK1556378 T3 DK 1556378T3
Authority
DK
Denmark
Prior art keywords
benzisothiazol
indo
piperazinyl
dihydro
chloro
Prior art date
Application number
DK03751112T
Other languages
Danish (da)
English (en)
Inventor
Timothy Norris
Roberto Colon-Cruz
Original Assignee
Pfizer Prod Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer Prod Inc filed Critical Pfizer Prod Inc
Application granted granted Critical
Publication of DK1556378T3 publication Critical patent/DK1556378T3/da

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing three or more hetero rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Biomedical Technology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Psychiatry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Indole Compounds (AREA)
  • Nitrogen- Or Sulfur-Containing Heterocyclic Ring Compounds With Rings Of Six Or More Members (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
DK03751112T 2002-10-24 2003-10-13 Acylderivater af 5-(2-(4-(1,2 benzisothiazol-3-yl)-1piperazinyl)ethyl)-6-chloro-1,3-dihydro-2H-indo-2-on med neuroleptisk aktivitet DK1556378T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US42084302P 2002-10-24 2002-10-24
PCT/IB2003/004519 WO2004037819A1 (en) 2002-10-24 2003-10-13 Acyl derivatives of 5-(2-(4-(1,2 benzisothiazole-3-yl)-1-piperazinyl)ethyl)-6-chloro-1,3-dihydro-2h-indol-2-one having neuroleptic activity

Publications (1)

Publication Number Publication Date
DK1556378T3 true DK1556378T3 (da) 2008-03-17

Family

ID=32176638

Family Applications (1)

Application Number Title Priority Date Filing Date
DK03751112T DK1556378T3 (da) 2002-10-24 2003-10-13 Acylderivater af 5-(2-(4-(1,2 benzisothiazol-3-yl)-1piperazinyl)ethyl)-6-chloro-1,3-dihydro-2H-indo-2-on med neuroleptisk aktivitet

Country Status (25)

Country Link
US (1) US7019009B2 (ja)
EP (1) EP1556378B1 (ja)
JP (1) JP2006505578A (ja)
KR (1) KR100755625B1 (ja)
CN (1) CN100340557C (ja)
AR (1) AR041695A1 (ja)
AT (1) ATE383357T1 (ja)
AU (1) AU2003269331B2 (ja)
BR (1) BR0315516A (ja)
CA (1) CA2500485C (ja)
CO (1) CO5550441A2 (ja)
CY (1) CY1107300T1 (ja)
DE (1) DE60318602T2 (ja)
DK (1) DK1556378T3 (ja)
ES (1) ES2297200T3 (ja)
HK (1) HK1081185A1 (ja)
MX (1) MXPA05002734A (ja)
NO (1) NO20052475L (ja)
NZ (1) NZ566615A (ja)
PL (1) PL376721A1 (ja)
PT (1) PT1556378E (ja)
RU (1) RU2005112254A (ja)
TW (1) TW200418850A (ja)
WO (1) WO2004037819A1 (ja)
ZA (1) ZA200502109B (ja)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2551346A1 (en) * 2003-12-31 2005-07-21 Warner-Lambert Company Llc N-substituted piperidine and piperazine derivatives
EP2445343B1 (en) * 2009-06-25 2021-08-04 Alkermes Pharma Ireland Limited Prodrugs of nh-acidic compounds
AU2010266018B2 (en) * 2009-06-25 2014-01-09 Alkermes Pharma Ireland Limited Heterocyclic compounds for the treatment of neurological and psychological disorders
NZ604423A (en) * 2010-06-24 2015-01-30 Alkermes Pharma Ireland Ltd Prodrugs of nh-acidic compounds: ester, carbonate, carbamate and phosphonate derivatives
EP2919788A4 (en) 2012-11-14 2016-05-25 Univ Johns Hopkins METHODS AND COMPOSITIONS FOR THE TREATMENT OF SCHIZOPHRENIA
US11273158B2 (en) 2018-03-05 2022-03-15 Alkermes Pharma Ireland Limited Aripiprazole dosing strategy

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5206366A (en) * 1992-08-26 1993-04-27 Pfizer Inc. Process for preparing aryl piperazinyl-heterocyclic compounds
US5312925A (en) * 1992-09-01 1994-05-17 Pfizer Inc. Monohydrate of 5-(2-(4-(1,2-benzisothiazol-3-yl)-1-piperazinyl)-ethyl)-6-chloro-1,3-dihydro-2H-indol-2-one-hydrochloride
EP0790236B1 (en) * 1996-02-13 2003-11-19 Pfizer Inc. Pro-drugs of 5-(2-(4-(1,2-benzisothiazol-3-yl)-1-piperazinyl)ethyl)-6-chloro-1,3-dihydro-2h-indol-2-one
DE69923692T2 (de) * 1998-08-20 2006-03-23 Sumitomo Pharmaceuticals Co., Ltd. Wachstumshormon-freisetzende oxindolderivate

Also Published As

Publication number Publication date
US7019009B2 (en) 2006-03-28
EP1556378A1 (en) 2005-07-27
AU2003269331B2 (en) 2010-02-18
KR20050065618A (ko) 2005-06-29
WO2004037819A1 (en) 2004-05-06
NO20052475D0 (no) 2005-05-23
KR100755625B1 (ko) 2007-09-04
US20040138232A1 (en) 2004-07-15
MXPA05002734A (es) 2005-05-23
ES2297200T3 (es) 2008-05-01
CY1107300T1 (el) 2012-11-21
NZ566615A (en) 2009-08-28
CA2500485A1 (en) 2004-05-06
CA2500485C (en) 2010-03-23
ATE383357T1 (de) 2008-01-15
HK1081185A1 (en) 2006-05-12
DE60318602D1 (de) 2008-02-21
CN100340557C (zh) 2007-10-03
CN1705663A (zh) 2005-12-07
PT1556378E (pt) 2008-02-21
ZA200502109B (en) 2006-05-31
EP1556378B1 (en) 2008-01-09
JP2006505578A (ja) 2006-02-16
TW200418850A (en) 2004-10-01
RU2005112254A (ru) 2006-01-20
NO20052475L (no) 2005-07-25
PL376721A1 (pl) 2006-01-09
CO5550441A2 (es) 2005-08-31
DE60318602T2 (de) 2009-01-15
AU2003269331A1 (en) 2004-05-13
AR041695A1 (es) 2005-05-26
BR0315516A (pt) 2005-08-23

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