DK1546151T3 - Antidepressive cycloalkylaminderivater af heterocyclus-annellerede benzodioxaner - Google Patents

Antidepressive cycloalkylaminderivater af heterocyclus-annellerede benzodioxaner

Info

Publication number
DK1546151T3
DK1546151T3 DK03795686T DK03795686T DK1546151T3 DK 1546151 T3 DK1546151 T3 DK 1546151T3 DK 03795686 T DK03795686 T DK 03795686T DK 03795686 T DK03795686 T DK 03795686T DK 1546151 T3 DK1546151 T3 DK 1546151T3
Authority
DK
Denmark
Prior art keywords
disorder
benzodioxanes
heterocycle
annealed
anxiety
Prior art date
Application number
DK03795686T
Other languages
Danish (da)
English (en)
Inventor
Gary Paul Stack
Deborah Ann Evrard
Uresh Shantilal Shah
Original Assignee
Wyeth Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Wyeth Corp filed Critical Wyeth Corp
Application granted granted Critical
Publication of DK1546151T3 publication Critical patent/DK1546151T3/da

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D498/00Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D498/02Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
    • C07D498/04Ortho-condensed systems
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D491/00Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
    • C07D491/02Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
    • C07D491/04Ortho-condensed systems
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00Drugs for genital or sexual disorders; Contraceptives
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00Drugs for genital or sexual disorders; Contraceptives
    • A61P15/10Drugs for genital or sexual disorders; Contraceptives for impotence
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/22Anxiolytics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/24Antidepressants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/30Drugs for disorders of the nervous system for treating abuse or dependence
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/30Drugs for disorders of the nervous system for treating abuse or dependence
    • A61P25/32Alcohol-abuse
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/04Anorexiants; Antiobesity agents

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Veterinary Medicine (AREA)
  • Neurosurgery (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Addiction (AREA)
  • Psychiatry (AREA)
  • Reproductive Health (AREA)
  • Endocrinology (AREA)
  • Pain & Pain Management (AREA)
  • Obesity (AREA)
  • Hematology (AREA)
  • Gynecology & Obstetrics (AREA)
  • Diabetes (AREA)
  • Child & Adolescent Psychology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
DK03795686T 2002-09-12 2003-09-11 Antidepressive cycloalkylaminderivater af heterocyclus-annellerede benzodioxaner DK1546151T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US41007202P 2002-09-12 2002-09-12
US10/659,174 US6911445B2 (en) 2002-09-12 2003-09-10 Antidepressant cycloalkylamine derivatives of heterocycle-fused benzodioxans

Publications (1)

Publication Number Publication Date
DK1546151T3 true DK1546151T3 (da) 2006-07-31

Family

ID=31997897

Family Applications (1)

Application Number Title Priority Date Filing Date
DK03795686T DK1546151T3 (da) 2002-09-12 2003-09-11 Antidepressive cycloalkylaminderivater af heterocyclus-annellerede benzodioxaner

Country Status (21)

Country Link
US (1) US6911445B2 (ko)
EP (1) EP1546151B1 (ko)
JP (1) JP2006503040A (ko)
KR (1) KR20050042187A (ko)
CN (1) CN1309722C (ko)
AT (1) ATE323094T1 (ko)
AU (1) AU2003266029A1 (ko)
BR (1) BR0314430A (ko)
CA (1) CA2498131A1 (ko)
DE (1) DE60304590T2 (ko)
DK (1) DK1546151T3 (ko)
EC (1) ECSP055659A (ko)
ES (1) ES2259776T3 (ko)
HK (1) HK1073849A1 (ko)
MX (1) MXPA05002838A (ko)
NO (1) NO20051770L (ko)
NZ (1) NZ539253A (ko)
PT (1) PT1546151E (ko)
RU (1) RU2005107591A (ko)
SI (1) SI1546151T1 (ko)
WO (1) WO2004024732A1 (ko)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
PE20060373A1 (es) 2004-06-24 2006-04-29 Smithkline Beecham Corp Derivados 3-piperidinil-7-carboxamida-indazol como inhibidores de la actividad cinasa de ikk2
PE20060748A1 (es) 2004-09-21 2006-10-01 Smithkline Beecham Corp Derivados de indolcarboxamida como inhibidores de quinasa ikk2
CA2597616A1 (en) * 2005-02-17 2006-08-24 Wyeth Cycloalkylfused indole, benzothiophene, benzofuran and indene derivatives
US8063071B2 (en) 2007-10-31 2011-11-22 GlaxoSmithKline, LLC Chemical compounds
US20080139546A1 (en) * 2006-09-29 2008-06-12 Wyeth Tetrahydroquinoline, indoline, and related aniline derivatives of heterocycle-fused benzodioxan methylamines
AR065804A1 (es) 2007-03-23 2009-07-01 Smithkline Beecham Corp Compuesto de indol carboxamida, composicion farmaceutica que lo comprende y uso de dicho compuesto para preparar un medicamento
WO2008150848A1 (en) * 2007-05-30 2008-12-11 Wyeth Antidepressant heteroaryl derivatives of heterocycle-fused benzodioxans
WO2010102968A1 (en) 2009-03-10 2010-09-16 Glaxo Group Limited Indole derivatives as ikk2 inhibitors

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9318431D0 (en) * 1993-09-06 1993-10-20 Boots Co Plc Therapeutic agents
US5468767A (en) * 1994-01-06 1995-11-21 Bristol-Myers Squibb Company Antidepressant 3-(aminocycloalkenyl)-indole-5-nitrile derivatives
AR004229A1 (es) * 1995-11-06 1998-11-04 Wyeth Corp Derivados indolalquilo de benzodioxanmetilamina y su uso para preparar medicamentos
GB9627005D0 (en) 1996-12-27 1997-02-12 Knoll Ag Therapeutic agents
GB9704948D0 (en) * 1997-03-11 1997-04-30 Knoll Ag Therapeutic agents
CA2327360A1 (en) * 1998-04-08 1999-10-14 Richard Eric Mewshaw Indol-3-yl-cyclohexyl amine derivatives for the treatment of depression (5-ht1 receptor antagonists)
US6162803A (en) * 1998-04-08 2000-12-19 American Home Products Corp. Indol-3-yl-cyclohexyl amine derivatives for the treatment of depression
WO2002072587A1 (en) 2001-03-14 2002-09-19 Wyeth Antidepressant azaheterocyclymethyl derivatives of 2,3-dihydro-1,4-dioxino[2,3-f]quinoline
ATE279415T1 (de) 2001-04-26 2004-10-15 Wyeth Corp Antidepressiv wirksame azaheterocyclymethyl- derivative von oxaheterocycyl-anellierten (1,4)- benzodioxanen

Also Published As

Publication number Publication date
NO20051770L (no) 2005-06-07
HK1073849A1 (en) 2005-10-21
MXPA05002838A (es) 2005-08-16
PT1546151E (pt) 2006-07-31
CN1309722C (zh) 2007-04-11
SI1546151T1 (sl) 2006-08-31
DE60304590T2 (de) 2007-05-10
RU2005107591A (ru) 2006-01-20
BR0314430A (pt) 2005-09-27
EP1546151B1 (en) 2006-04-12
WO2004024732A1 (en) 2004-03-25
JP2006503040A (ja) 2006-01-26
CN1681821A (zh) 2005-10-12
EP1546151A1 (en) 2005-06-29
ES2259776T3 (es) 2006-10-16
ECSP055659A (es) 2005-07-06
CA2498131A1 (en) 2004-03-25
NZ539253A (en) 2006-09-29
US6911445B2 (en) 2005-06-28
AU2003266029A1 (en) 2004-04-30
DE60304590D1 (de) 2006-05-24
US20040171667A1 (en) 2004-09-02
KR20050042187A (ko) 2005-05-04
ATE323094T1 (de) 2006-04-15

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